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■ Abbreviation / Long Form : 11beta-HSD / 11beta-hydroxysteroid dehydrogenase

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Total Number of Papers: 560
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Abbreviation:   11beta-HSD  (>> Co-occurring Abbreviation)
Long Form:   11beta-hydroxysteroid dehydrogenase
 Abbreviation Variation
 Long Form Variation
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No. Year Title Co-occurring Abbreviation
2021 11β-hydroxysteroid dehydrogenases: A growing multi-tasking family. 11betaHSD1L, MetS, RORgamma
2021 Endogenous Glucocorticoid Metabolism in Bone: Friend or Foe. GCs
2021 Modulation of 11β-hydroxysteroid dehydrogenase functions by the cloud of endogenous metabolites in a local microenvironment: The glycyrrhetinic acid-like factor (GALF) hypothesis. GALF, GALFs, GR, MR
2021 Steroid-converting enzymes in human adipose tissues and fat deposition with a focus on AKR1C enzymes. ---
2020 Endogenous urinary glucocorticoid metabolites and mortality in prednisolone-treated renal transplant recipients. RTR, THE
2020 Reciprocal Regulation of HSD11B1 and HSD11B2 Predicts Glucocorticoid Sensitivity in Childhood Acute Lymphoblastic Leukemia. ALL
2020 Significance of glucocorticoid signaling in triple-negative breast cancer patients: a newly revealed interaction with androgen signaling. DEX, DHT, GCs, GR, AR, SGK1, TNBC
2020 Synthesis of Novel 2-(Isopropylamino)thiazol-4(5H)-one Derivatives and Their Inhibitory Activity of 11beta-HSD1 and 11beta-HSD2 in Aspect of Carcinogenesis Prevention. ---
2020 Two new sesquiterpenes from cultures of the fungus Irpex lacteus. ---
10  2020 [Genetic expression differences of 11 beta-hydroxysteroid dehydrogenase in the bone microvascular endothelial cells derived from different regions of the human femoral head]. BMECs, RT-PCR
11  2019 11alpha-Hydroxyprogesterone, a potent 11beta-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5alpha-reductase and cytochrome P450 17alpha-hydroxylase/17,20-lyase to produce C11alpha-derivatives of 21-deoxycortisol and 11-hydroxyandrostenedione in vitro. CYP17A1, SRD5A
12  2019 11beta-Hydroxysteroid dehydrogenases control access of 7beta,27-dihydroxycholesterol to retinoid-related orphan receptor gamma. 7-KC, 7beta-OHC, 7beta27OHC, 7k27OHC, RORgamma
13  2019 A Review of the Pharmacological Efficacy and Safety of Licorice Root from Corroborative Clinical Trial Findings. ---
14  2019 Application of ELISA Technique and Human Microsomes in the Search for 11beta-Hydroxysteroid Dehydrogenase Inhibitors. ---
15  2019 Endocrine modulation of Brucella abortus-infected osteocytes function and osteoclastogenesis via modulation of RANKL/OPG. Cx43, GR
16  2019 Phenotypic flexibility of glucocorticoid signaling in skeletal muscles of a songbird preparing to migrate. CORT, GR, MR
17  2019 Physiological effects of 5alpha-dihydrotestosterone in male mummichog (Fundulus heteroclitus) are dose and time dependent. 11-KT, 17beta-HSD, 3beta-HSD, CYP17A1, DHT, StAR
18  2019 Role of gut metabolism of adrenal corticosteroids and hypertension: clues gut-cleansing antibiotics give us. ---
19  2019 The 11beta-hydroxysteroid dehydrogenase isoforms: pivotal catalytic activities yield potent C11-oxy C19 steroids with 11betaHSD2 favouring 11-ketotestosterone, 11-ketoandrostenedione and 11-ketoprogesterone biosynthesis. ---
20  2019 The impact of early-life stress on corticosteroid carrier protein levels and 11beta-hydroxysteroid dehydrogenase 1 expression in adolescent rats. CBG, ELS, MS
21  2019 [Study on the relationship between 11beta-hydroxysteroid dehydrogenase and glucocorticoid response in nasal polyps]. CRSwNP, insensitive group, ROC, RT-PCR, sensitive group
22  2018 11beta-hydroxysteroid dehydrogenases as targets in the treatment of steroid-associated femoral head necrosis using antler extract. ALP, ANFH, CT, SANFH
23  2018 A new guaiane sesquiterpene from cultures of the fungus Fulvifomes kanehirae. ---
24  2018 A new tremulane sesquiterpenoid from the fungus Irpex lacteus. ---
25  2018 Antenatal exposure to betamethasone induces placental 11beta-hydroxysteroid dehydrogenase type 2 expression and the adult metabolic disorders in mice. IUGR
26  2018 Comparison of steroidogenic gene expression in mummichog (Fundulus heteroclitus) testis tissue following exposure to aromatizable or non-aromatizable androgens. 3beta-HSD, cyp11a1, CYP17A1, DHT, MT
27  2018 Factors impacting on the action of glucocorticoids in patients receiving glucocorticoid therapy. ACTH, AI, GCs, HPA
28  2018 Glucocorticoid activation by 11beta-hydroxysteroid dehydrogenase enzymes in relation to inflammation and glycaemic control in chronic kidney disease: A cross-sectional study. CKD, eGFR, THE
29  2018 Learning pharmacokinetic models for in vivo glucocorticoid activation. ---
30  2018 Monomeric and oligomeric flavanols maintain the endogenous glucocorticoid response in human macrophages in pro-oxidant conditions in vitro. IL, MOF, t-BuOOH
31  2018 Role of tissue-specific steroid metabolism in oral disease: Is there any clinical implication? ---
32  2018 Swimming exercise to control precocious maturation in male seabass (Dicentrarchus labrax). 3-beta-HSD, AMH, BW, fshR, gsdf1, SL, smc1beta
33  2017 11beta-Hydroxysteroid Dehydrogenase Type 1 in Obese Subjects With Type 2 Diabetes Mellitus. ---
34  2017 A maternal high-fat, high-sucrose diet has sex-specific effects on fetal glucocorticoids with little consequence for offspring metabolism and voluntary locomotor activity in mice. HFHS
35  2017 A new cadinane sesquiterpenoid from cultures of the Basidiomycete Panus conchatus. ---
36  2017 Changes in 11beta-Hydroxysteroid Dehydrogenase and Glucocorticoid Receptor Expression in Kawasaki Disease. GR, KD
37  2017 Gastroprotective effect of calealactone B: Lack of involvement of prostaglandins, nitric oxide and sulfhydryls. NO
38  2017 In obese mice, exercise training increases 11beta-HSD1 expression, contributing to glucocorticoid activation and suppression of pulmonary inflammation. 3beta-HSD, GCs, IL, MCP
39  2017 Knotting nets: Molecular junctions of interconnecting endocrine axes identified by application of the adverse outcome pathway concept. AOP, HPA/I, HPG, HPT, StAR
40  2017 Normalisation of surfactant protein -A and -B expression in the lungs of low birth weight lambs by 21 days old. AEC, GR, IUGR, LAMP, LBW, PR, SP
41  2017 Recent advances in the study of 11beta-Hydroxysteroid dehydrogenase type 2 (11beta-HSD2)Inhibitors. AME
42  2017 The Effects of Sertraline on Fathead Minnow (Pimephales promelas) Growth and Steroidogenesis. 20beta-HSD, FHM, TRalpha, TRbeta
43  2017 Transfer and Metabolism of Cortisol by the Isolated Perfused Human Placenta. ---
44  2016 11beta-hydroxysteroid dehydrogenase inhibition as a new potential therapeutic target for alcohol abuse. ---
45  2016 11beta-hydroxysteroid dehydrogenase-1 deficiency alters the gut microbiome response to Western diet. ---
46  2016 Carbenoxolone exposure during late gestation in rats alters placental expressions of p53 and estrogen receptors. dg, IUGR
47  2016 Cortisol metabolism, postnatal depression and weight changes in the first 12 months postpartum. ---
48  2016 Cortisol-Metabolizing Enzymes in Polycystic Ovary Syndrome. 5alpha-R, 5betaR, BMI, GC-MS, PCOS
49  2016 Dysregulation of 11beta-hydroxysteroid dehydrogenases: implications during pregnancy and beyond. ---
50  2016 Expression and regulation of 11beta-hydroxysteroid dehydrogenase type 1 in first trimester human decidua cells: Implication in preeclampsia. ---
51  2016 Intraindividual stability of cortisol and cortisone and the ratio of cortisol to cortisone in saliva, urine and hair. HPA, ICC
52  2016 Local cortisol/corticosterone activation in skin physiology and pathology. 11-DHC, GCs, HPA
53  2015 Determination of seven selected neuro- and immunomodulatory steroids in human cerebrospinal fluid and plasma using LC-MS/MS. CSF, DHEA
54  2015 Determination of the topology of endoplasmic reticulum membrane proteins using redox-sensitive green-fluorescence protein fusions. 17beta-HSD, ER, roGFP
55  2015 Effect of Luteolin on 11Beta-Hydroxysteroid Dehydrogenase in Rat Liver and Kidney. EP, GC
56  2015 Tissue specific regulation of glucocorticoids in severe obesity and the response to significant weight loss following bariatric surgery (BARICORT). BMI, OM
57  2015 Two new sesquiterpenoids from cultures of the basidiomycete Tremella foliacea. ---
58  2014 A mechanism for rapid neurosteroidal regulation of parenting behaviour. CBX
59  2014 Cortisol and cortisone ratio in urine: LC-MS/MS method validation and preliminary clinical application. LLOQ
60  2014 Cross-talk between adipose tissue and the HPA axis in obesity and overt hypercortisolemic states. AT, GC, HPA, V-BFD, WAT
61  2014 Differential expression of 11beta-hydroxysteroid dehydrogenase type 1 and 2 in mild and moderate/severe persistent allergic nasal mucosa and regulation of their expression by Th2 cytokines: asthma and rhinitis. ---
62  2014 Endocrine disruptors and other inhibitors of 11beta-hydroxysteroid dehydrogenase 1 and 2: Tissue-specific consequences of enzyme inhibition. EDs
63  2014 Expression of 11beta-hydroxysteroid dehydrogenase isoforms in canine adrenal glands treated with trilostane. ---
64  2014 Glucocorticoids and renal Na+ transport: implications for hypertension and salt sensitivity. ---
65  2014 Hepatic 11beta-hydroxysteroid dehydrogenase type 1 activity in obesity and type 2 diabetes using a novel triple tracer cortisol technique. D cortisol, LND, OND
66  2014 Insulin, CCAAT/enhancer-binding proteins and lactate regulate the human 11beta-hydroxysteroid dehydrogenase type 2 gene expression in colon cancer cell lines. ---
67  2014 Intrafollicular cortisol levels inversely correlate with cumulus cell lipid content as a possible energy source during oocyte meiotic resumption in women undergoing ovarian stimulation for in vitro fertilization. CC, FF, HSL, IVF, LPL
68  2014 Pharmacophore Model Refinement for 11beta-Hydroxysteroid Dehydrogenase Inhibitors: Search for Modulators of Intracellular Glucocorticoid Concentrations. ---
69  2014 Reductive metabolism of nabumetone by human liver microsomal and cytosolic fractions: exploratory prediction using inhibitors and substrates as marker probes. AKR, CBR, MNBO
70  2014 Simultaneous measurements of cortisol and cortisone in urine and hair for the assessment of 11beta-hydroxysteroid dehydrogenase activity among methadone maintenance treatment patients with LC-ESI-MS/MS. ---
71  2013 11beta-hydroxyandrostenedione, the product of androstenedione metabolism in the adrenal, is metabolized in LNCaP cells by 5alpha-reductase yielding 11beta-hydroxy-5alpha-androstanedione. 11OH-5alpha-dione, CYP11B1, CYP11B2
72  2013 11β-hydroxysteroid dehydrogenases: intracellular gate-keepers of tissue glucocorticoid action. MR
73  2013 7alpha-hydroxylation of dehydroepiandrosterone does not interfere with the activation of glucocorticoids by 11beta-hydroxysteroid dehydrogenase in E(t)C cerebellar neurons. 7alpha-OH-DHEA, DHEA, H6PDH
74  2013 Characteristics of novel hair-based biomarker for the activity assessment of 11beta-hydroxysteroid dehydrogenase. ---
75  2013 Environmental stress-induced testis differentiation: androgen as a by-product of cortisol inactivation. 11-KT, TSD
76  2013 Expression profiles of cortisol-inactivating enzyme, 11beta-hydroxysteroid dehydrogenase-2, in human epidermal tumors and its role in keratinocyte proliferation. BCC, SCC, SK, TPA
77  2013 Main metabolic pathways of TAK-802, a novel drug candidate for voiding dysfunction, in humans: the involvement of carbonyl reduction by 11beta-hydroxysteroid dehydrogenase 1. ---
78  2013 Ovarian 11beta-hydroxysteroid dehydrogenase (11betaHSD) activity is suppressed in women with anovulatory polycystic ovary syndrome (PCOS): apparent role for ovarian androgens. PCO, PCOS
79  2013 Ovarian localization of 11beta-hydroxysteroid dehydrogenase (11betaHSD): effects of ACTH stimulation and its relationship with bovine cystic ovarian disease. COD
80  2013 Primary male osteoporosis is associated with enhanced glucocorticoid availability. MO
81  2013 Regulation of glucocorticoid metabolism in the boar testis and caput epididymidis by the gonadotrophin-cAMP signalling pathway. PKA
82  2013 Remission of hypertension and electrolyte abnormalities following renal transplantation in a patient with apparent mineralocorticoid excess well documented throughout childhood. AME
83  2013 Synthesis of sterically encumbered 11beta-aminoprogesterone derivatives and evaluation as 11beta-hydroxysteroid dehydrogenase inhibitors and mineralocorticoid receptor antagonists. MR
84  2013 The expression of 11beta-HSDs, GR, and H6PDH in subcutaneous adipose tissue from polycystic ovary syndrome subjects. GR, H6PDH, HOMA-IR, HOMA-IS, PCOS, SAT, TNF-alpha
85  2012 11beta-hydroxysteroid dehydrogenase type 1 is expressed in human sebaceous glands and regulates glucocorticoid-induced lipid synthesis and toll-like receptor 2 expression in SZ95 sebocytes. GCs, siRNA, SREBP-1, TLR2
86  2012 Distribution of glucocorticoid receptors and 11beta-hydroxysteroid dehydrogenase isoforms in the human inner ear. GCs, GRs, MD, SV
87  2012 Expression of 11beta-hydroxysteroid dehydrogenase type 1 and glucocorticoid receptors in reproductive tissue of male horses at different stages of sexual maturity. GCR, GCs, IHC, NAD, qRT-PCR
88  2012 Gene expression of ACTH, glucocorticoid receptors, 11betaHSD enzymes, LH-, FSH-, GH receptors and aromatase in equine epididymal and testicular tissue. FSHR, GAPDH, GCs, GHR, LHR, MC2R
89  2012 IL-13-induced changes in endogenous glucocorticoid metabolism in the lung regulate the proasthmatic response. CBX, GC
90  2012 Local amplification of glucocorticoids in the aging brain and impaired spatial memory. GCs, KO
91  2012 Mediastinal adipose tissue expresses a pathogenic profile of 11 beta-hydroxysteroid dehydrogenase Type 1, glucocorticoid receptor, and CD68 in patients with coronary artery disease. CAD, CAD, GCR
92  2012 Steroids and their metabolites in CSF from shunt as potential predictors of further disease progression in patients with hydrocephalus and the importance of 11beta-hydroxysteroid dehydrogenase. CSF
93  2012 The effect of glycyrrhetinic acid on pharmacokinetics of cortisone and its metabolite cortisol in rats. GA
94  2012 The in vitro metabolism of cortisol by ovarian follicles of rainbow trout (Oncorhynchus mykiss): comparison with ovulated oocytes and pre-hatch embryos. GST, YF
95  2012 Validation and application of a highly specific and sensitive ELISA for the estimation of cortisone in saliva, urine and in vitro cell-culture media by using a novel antibody. ---
96  2011 11β-Hydroxysteroid dehydrogenase type 1, but not type 2, deficiency worsens acute inflammation and experimental arthritis in mice. ---
97  2011 Age-related changes in corticosteroid receptor expression and monoamine neurotransmitter concentrations in various brain regions of postnatal pigs. GR, MR
98  2011 Cyclopeptide Alkaloids from Ziziphus apetala. ---
99  2011 Distribution of glucocorticoid receptors and 11 beta-hydroxysteroid dehydrogenase isoforms in the rat inner ear. CN, DCs, GRs, IHCs, OHCs, PCR, RM, SGCs, SLib, SLig, SV, VHCs, VN
100  2011 Elevated glucocorticoid metabolism in placental tissue from first trimester pregnancies at increased risk of pre-eclampsia. ---