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■ Abbreviation / Long Form : 5-HT / 5-hydroxytryptamine

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Abbreviation:   5-HT  (>> Co-occurring Abbreviation)
Long Form:   5-hydroxytryptamine
 Abbreviation Variation
 Long Form Variation
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No. Year Title Co-occurring Abbreviation
2019 5-HT1A autoreceptor in dorsal raphe nucleus mediates sensitization of conditioned place preference to cocaine in mice experienced with chronic pain. DRN
2019 5-Hydroxytryptamine (5-HT)-exacerbated DSS-induced colitis is associated with elevated NADPH oxidase expression in the colon. DSS, IHC, mRNA, qPCR
2019 5-Hydroxytryptamine and Dopamine Neurons in the Cerebellum of the New-Hatching Yangtze Alligator Alligator sinensis. 5-HT-IR, DA, DA-IR
2019 5-Hydroxytryptamine1a receptors on tumour cells induce immune evasion in lung adenocarcinoma patients with depression via autophagy/pSTAT3. 5-HT1aRs, FACS, IHC, STAT3
2019 A neural circuit for comorbid depressive symptoms in chronic pain. CDS, CeA, SOM
2019 Abnormalities of mucosal serotonin metabolism and 5-HT3 receptor subunit 3C polymorphism in irritable bowel syndrome with diarrhoea predict responsiveness to ondansetron. IBS-D, SNPs
2019 Activation and blockade of dorsal hippocampal Serotonin6 receptors regulate anxiety-like behaviors in a unilateral 6-hydroxydopamine rat model of Parkinson's disease. 6-OHDA, DA, dHip, EPM, NA, PD
2019 Alarin in different human intestinal epithelial cell types. AL, Cg, PY, second set, SO, SY
2019 Alkaloids from the rhizomes of Ligusticum striatum exert antimigraine effects through regulating 5-HT1B receptor and c-Jun. PAG, RCX, RCX, TAs
10  2019 Ameliorative effect of Xiaoyao-jieyu-san on post-stroke depression and its potential mechanisms. BDNF, CRF, CUMS, MCAO, NE, PSD, VTA-NAc, XYJY
11  2019 Anti-Migraine Effect of the Herbal Combination of Chuanxiong Rhizoma and Cyperi Rhizoma and UPLC-MS/MS Method for the Simultaneous Quantification of the Active Constituents in Rat Serum and Cerebral Cortex. 5-HIAA, BDPH, beta-EP, CGRP, CRCR, CYP, CYT, ET-1, FA, GABA, LIG, NBP, NKT, NO, NOS, NTG, SA
12  2019 Antiallodynic Effect of Intrathecal Korean Red Ginseng in Cisplatin-Induced Neuropathic Pain Rats. CINP, DHE, KRG
13  2019 Antidepressant effect of helicid in chronic unpredictable mild stress model in rats. BDNF, CORT, CUMS
14  2019 Antidepressant-Like Action of Single Facial Injection of Botulinum Neurotoxin A is Associated with Augmented 5-HT Levels and BDNF/ERK/CREB Pathways in Mouse Brain. BDNF, p-ERK, SRS
15  2019 Antioxidant and Anti-Stress Effects of Taurine Against Electric Foot-Shock-Induced Acute Stress in Rats. 5-HIAA, CAT, DHEAS, GPx, GST
16  2019 Antipsychotics for patients with pain. IASP
17  2019 Anxiolytic Effect of Cedrol on Behavior and Brain Neurotransmitter Levels of Female Mice. 5-HIAA, DA, DOPAC, EPM, i.p, LDB
18  2019 Apparent Correlations Between AMPK Expression and Brain Inflammatory Response and Neurological Function Factors in Rats with Chronic Renal Failure. AMPK, BDNF, BUN, ICAM-1, IL-1, SCr, TNF-alpha
19  2019 Central 5-hydroxytryptamine (5-HT) mediates colonic motility by hypothalamus oxytocin-colonic oxytocin receptor pathway. KO, OT, WT
20  2019 Changes in Cold and Hot Syndrome and Gastrointestinal Bacterial Community Structure in Mice by Intervention with Food of Different Nature. cAMP, cGMP, NE, RW, TSH, TW
21  2019 Changes in gonadal function at different stages of chronic restraint stress-induced depression animals. CRS, OFT
22  2019 Characterization of serotonin following exposure to antibiotics in white-tailed deer. AGP, CTC
23  2019 Chrysin ameliorates ANTU-induced pulmonary edema and pulmonary arterial hypertension via modulation of VEGF and eNOs. ANTU, GGT, LDH, PAH, PE, RV
24  2019 Cytochrome P450 enzymes contribute to the metabolism of LSD to nor-LSD and 2-oxo-3-hydroxy-LSD: Implications for clinical LSD use. LSD, nor-LSD, O-H-LSD
25  2019 Deficiency of ZnT8 Promotes Adiposity and Metabolic Dysfunction by Increasing Peripheral Serotonin Production. ---
26  2019 Distribution and co-expression patterns of specific cell markers of enteroendocrine cells in pig gastric epithelium. ECL, EEC
27  2019 Distributions and relationships of chemically defined enteroendocrine cells in the rat gastric mucosa. EEC, PYY, VIP
28  2019 Dorsal raphe nucleus 5-Hydroxytryptamine 2A receptors are critical for the organisation of panic attack-like defensive behaviour and unconditioned fear-induced antinociception elicited by the chemical stimulation of superior colliculus neurons. dlSC, DRN, NMDA, SC
29  2019 Dual excitatory and smooth muscle-relaxant effect of beta-phenylethylamine on gastric fundus strips in rats. beta-PEA, TAARs
30  2019 Effects of a new magnesium-rich artificial cerebrospinal fluid on contractile 5-hydroxytryptamine and endothelin receptors in rat cerebral arteries. 5-HT1B, CSF, ET-1, ETA, ETB, MACSF, mRNA, PCR, S6c, SAH
31  2019 Effects of chronic mild stress induced depression on synaptic plasticity in mouse hippocampus. CMS, DA
32  2019 Effects of plus-maze experience and chlordiazepoxide on anxiety-like behavior and serotonin neural activity in the dorsal raphe nucleus in rats. DRN, EPM
33  2019 Effects of separate or combined exposure of nonylphenol and octylphenol on central 5-HT system and related learning and memory in the rats. 5-HT1A, 5-HT3A, 5-HT3B, 5-HT4A, 5-HT6A, ERbeta, MAOA, NO, NP, OP, SERT, TPH2, VMAT2
34  2019 Efficacy of ginkgo biloba extract as augmentation of venlafaxine in treating post-stroke depression. ADL, BDNF, HDRS, NIHSS, PSD, SDS
35  2019 Electroacupuncture for chemotherapy-induced anorexia through humoral appetite regulation: A preliminary experimental study. BDNF, CCK, CIA, EA, NTS
36  2019 Embracing diversity in the 5-HT neuronal system. ---
37  2019 Enhancement by Hydrogen Peroxide of Calcium Signals in Endothelial Cells Induced by 5-HT1B and 5-HT2B Receptor Agonists. HUVEC, ROS
38  2019 Evidence for protein kinase involvement in the 5-HT-[Ca2+ ]i -pannexin-1 signalling pathway in type II glial cells of the rat carotid body. CB, I5-HT, Panx-1
39  2019 Fenfluramine-induced PVAT-dependent contraction depends on norepinephrine and not serotonin. NET, PVAT, RA, SMA
40  2019 Fluoxetine adjunct to therapeutic exercise promotes motor recovery in rats with cerebral ischemia: Roles of nucleus accumbens. 5-HT2CR, MCAO, NAc
41  2019 Fluoxetine oral treatment discloses 5-HT1D receptor as vagoinhibitor of the cardiac cholinergic neurotransmission in rat. 5-HT1D agonist
42  2019 Glucagon-Like Peptide-1 (GLP-1) and 5-Hydroxytryptamine 2c (5-HT2c) Receptor Agonists in the Ventral Tegmental Area (VTA) Inhibit Ghrelin-Stimulated Appetitive Reward. 5-HT2c, Ex-4, GLP-1, i.p, PR3, VTA
43  2019 Heat Stress Modulates Brain Monoamines and Their Metabolites Production in Broiler Chickens Co-Infected with Clostridium perfringens Type A and Eimeria spp. 5-HIAA, DA, DOPAC, HPA, HVA, MHPG, NE
44  2019 Hesperidin Improves Colonic Motility in Loeramide-Induced Constipation Rat Model via 5-Hydroxytryptamine 4R/cAMP Signaling Pathway. CREB, STC
45  2019 Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3. ---
46  2019 Influence of Xiaoyaosan on depressive-like behaviors in chronic stress-depressed rats through regulating tryptophan metabolism in hippocampus. CIS, IDO1, NSF, OFT, qRT-PCR, SD, SPT, TPH2
47  2019 Intrahippocampal administration of 5-HT6 receptor drugs on memory consolidation and amnesia protocols. CR
48  2019 Lactobacillus casei Strain Shirota Alleviates Constipation in Adults by Increasing the Pipecolinic Acid Level in the Gut. ACh, LcS, PIPA
49  2019 LC-MS/MS combined with in vivo microdialysis sampling from conscious rat striatum for simultaneous determination of active constituents of Yuanhu- Baizhi herb pair and endogenous neurotransmitters: Application to pharmacokinetic and pharmacodynamic study. DA, Glu, PD, PK, YB
50  2019 LC-MS/MS-based quantification of tryptophan metabolites and neurotransmitters in the serum and brain of mice. 3-HK, 5-HIAA, ACh, CMS, GABA, Glu, Kyn, KYNA, NE, Trp
51  2019 Low-dose bisphenol A exposure impairs learning and memory ability with alterations of neuromorphology and neurotransmitters in rats. BPA, GABA, Glu
52  2019 MDMA modulates 5-HT1-mediated contractile response of the human internal thoracic artery in vitro. ---
53  2019 MK212, a 5-hydroxytryptamine 2C receptor agonist, inhibits conditioned avoidance responses independent of blocking endogenous dopamine release in rats. ---
54  2019 Multi-target design strategies for the improved treatment of Alzheimer's disease. AChE, AD, GSK-3beta, MAOs, NMDA, PDEs
55  2019 Neuroplastin 65 modulates anxiety- and depression-like behavior likely through adult hippocampal neurogenesis and central 5-HT activity. Np65, Np65 KO
56  2019 Neuroprotection by 2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside extracts from Polygonum multiflorum against cerebral ischemia/reperfusion injury through the 5-hydroxytryptamine/5-hydroxytryptamine receptor pathway. 5-HT2A, 5-HTT, I/R, MCAO, TSG, UCP4
57  2019 Nitric oxide plays a critical role in methotrexate-induced hyperplasia of enterochromaffin cells containing 5-hydroxytryptamine in rat small intestine. iNOS, l-NAME, NO
58  2019 Palmatine plays a role in sedation and hypnosis by increasing 5-hydroxytryptamine. ---
59  2019 Peroxidase Sensitive Amplifiable Probe for Molecular Magnetic Resonance Imaging of Pulmonary Inflammation. MRI
60  2019 Physicochemical properties and laxative effects of polysaccharides from Anemarrhena asphodeloides Bge. in loperamide-induced rats. AABP, ELISA, GAS, HPGPC, HPLC, MTL, PCR, SP, VIP
61  2019 Pilose Antler Extracts (PAEs) Protect against Neurodegeneration in 6-OHDA-Induced Parkinson's Disease Rat Models. 5-HIAA, CSF, DA, DOPAC, GAP-43, Glu, HE, HVA, IHC, NF-H, PAEs, PD, SNc, TH
62  2019 PM2.5 upregulates rat mesenteric arteries 5-HT2A receptor via inflammatory-mediated mitogen-activated protein kinases signaling pathway. MAPK
63  2019 Potential Antimigraine Effects of Warfarin: An Exploration of Biological Mechanism with Survey of Patients. MIDAS
64  2019 Prolongation of bronchopulmonary C-fiber-mediated apnea by prenatal nicotinic exposure in rat pups: role of 5-HT3 receptors. 5-HT3R, IR, PCFs, PNE
65  2019 Propofol Relaxes Isolated Rat Aorta through BKCa Activation. PE, RA
66  2019 Quercetin Attenuates Visceral Hypersensitivity and 5-Hydroxytryptamine Availability in Postinflammatory Irritable Bowel Syndrome Rats: Role of Enterochromaffin Cells in the Colon. EC, IBS, PI-IBS, TPH
67  2019 RANKL-induced osteoclastogenesis in bone marrow-derived macrophages is suppressed by cisapride. ALP, BMMs, RANKL, TRAP
68  2019 Reduction of Tryptophan Hydroxylase Expression in the Brain of Medaka Fish After Repeated Heat Stress. Hsp90alpha, TPH
69  2019 Repeated administration of methylphenidate produces reinforcement and downregulates 5-HT-1A receptor expression in the nucleus accumbens. ADHD, CPP, MPD
70  2019 Resveratrol Improves Brain-Gut Axis by Regulation of 5-HT-Dependent Signaling in the Rat Model of Irritable Bowel Syndrome. AWR, BDNF, CACS, IBS, ITM, pCREB
71  2019 Review of antidepressants in clinic and active ingredients of traditional Chinese medicine targeting 5-HT1A receptors. ---
72  2019 Role of Extracellular Calcium and Calcium Sensitization in the Anti-Contractile Effect of Perivascular Adipose Tissue in Pregnant Rat Aorta. PVAT, ROCK
73  2019 Rostral ventromedial medulla-mediated descending facilitation following P2X7 receptor activation is involved in the development of chronic post-operative pain. 5-HT3R, CPSP, P2X7R, RVM, SMIR
74  2019 Serotonergic system, cognition, and BPSD in Alzheimer's disease. 5-HTRs, AD, BPSD
75  2019 Serotonin receptor 3B polymorphisms are associated with type 2 diabetes: The Korean Genome and Epidemiology Study. KoGES, SNPs
76  2019 Spinal 5-HT3 receptor contributes to somatic hyperalgesia induced by sub-chronic stress. FS
77  2019 Stimulatory Effect of 5-Hydroxytryptamine (5-HT) on Rat Capsaicin-Sensitive Lung Vagal Sensory Neurons via Activation of 5-HT3 Receptors. CSLV
78  2019 Structural Modification of the Antidepressant Mianserin Suggests That Its Anti-inflammatory Activity May Be Independent of 5-Hydroxytryptamine Receptors. ---
79  2019 Structure-activity relationship of serotonin derived tocopherol lipids. DOPC, DOPE
80  2019 Synthesis and Evaluation of Antidepressant Activities of 5-Aryl-4,5-dihydrotetrazolo [1,5-a]thieno[2,3-e]pyridine Derivatives. FST, TST
81  2019 TAS-203, an oral phosphodiesterase 4 inhibitor, exerts anti-inflammatory activities in a rat airway inflammation model. AHR, BAL, cAMP, COPD, EGF, IL, MCP-1, PDE4, sRaw
82  2019 The comprehensive pathophysiological changes in a novel rat model of postinflammatory visceral hypersensitivity. 5-HT3AR, CRD, CRHR, CUMS, IBS, TNBS, VH
83  2019 The role of gonadal hormones in the hypoglossal discharge activity of rats exposed to chronic intermittent hypoxia. CIH
84  2019 The Role of Two-Pore Channels in Norepinephrine-Induced [Ca2+]i Rise in Rat Aortic Smooth Muscle Cells and Aorta Contraction. Ang II, NAADP, NE, SMCs, TPCs
85  2019 Therapeutic effects of Erbin inhibitor on spinal cord contusion in mice. ROS
86  2019 Treadmill Exercise Ameliorates Chemotherapy-Induced Muscle Weakness and Central Fatigue by Enhancing Mitochondrial Function and Inhibiting Apoptosis. DOX, TPH
87  2019 Treadmill exercise ameliorates nicotine withdrawal-induced symptoms. BrdU, TPH, TrkB
88  2019 Tropisetron attenuates tumor growth and progression in an experimental model of mouse lung cancer. i.p, IFN-gamma, IL
89  2019 Uncovering pharmacological mechanisms of Zhi-Zi-Hou-Po decoction in chronic unpredictable mild stress induced rats through pharmacokinetics, monoamine neurotransmitter and neurogenesis. CUMS, DA, SERT, TH, TPH2, Trp, Tyr, ZZHPD
90  2019 Urinary and plasmatic metabolomics strategy to explore the holistic mechanism of lignans in S. chinensis in treating Alzheimer's disease using UPLC-Q-TOF-MS. ACh, AD, Asp, GABA, Gly, MWM, NE, UPLC-Q-TOF-MS
91  2019 [Cloning and expression characteristics of tryptophan hydroxylase (TRH) from silkworm, Bombyx mori]. 5-HTP, BmPAH, BmTRH, CNS, ORF, TRH
92  2019 [Effect of otopoint pellet-pressing combined with medication on clinical symptoms of migraine patients and changes of plasma 5-HT and CGRP contents]. CGRP
93  2019 [Electroacupuncture improves insomnia by down-regulating peripheral benzodiazepine receptor expression in hippocampus, and up-regulating 5-HT, 5-HIAA, TNF-alpha and IL-1beta contents in hypothalamus in insomnia rats]. 5-HIAA, EA, i.p, IL, PBR, TNF-alpha
94  2019 [Protective effects on hippocampal neurons and the influence on hippocampal monoamine neurotransmitters with acupuncture for promoting the circulation of the governor vessel and regulating the mental state in rats with post-stroke depression]. DA, NE
95  2019 [Research progress on the mechanism of 5-hydroxytryptamine in sepsis]. SSRIs
96  2018 5-HT2 and 5-HT2B antagonists attenuate pro-fibrotic phenotype in human adult dermal fibroblasts by blocking TGF-beta1 induced non-canonical signaling pathways including STAT3 : implications for fibrotic diseases like scleroderma. alpha-SMA, HADF, TGF-beta1
97  2018 5-HT2A receptor is the predominant receptor mediating contraction of the isolated porcine distal ureter to 5-HT in young and old animals. ---
98  2018 A sensitive method for the determination of the gender difference of neuroactive metabolites in tryptophan and dopamine pathways in mouse serum and brain by UHPLC-MS/MS. 5-HIAA, DA, DNS-Cl, DOPAC, NE, SPE, Trp
99  2018 An Investigation on the Clinical Features and Neurochemical Changes in Parkinson's Disease With Depression. CSF, DA, FS, HAM-D, HAMA, PDD, PIGD
100  2018 Analogous beta-Carboline Alkaloids Harmaline and Harmine Ameliorate Scopolamine-Induced Cognition Dysfunction by Attenuating Acetylcholinesterase Activity, Oxidative Stress, and Inflammation in Mice. ACh, AChE, AD, Ch, ChAT, HAL, HAR, L-Glu, L-Trp