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■ Abbreviation / Long Form : 5-aza / 5-azacytidine

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Total Number of Papers: 218
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Abbreviation:   5-aza  (>> Co-occurring Abbreviation)
Long Form:   5-azacytidine
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No. Year Title Co-occurring Abbreviation
2020 5-Azacitidine Induces NOXA to Prime AML Cells for Venetoclax-Mediated Apoptosis. AML, Bcl-2, ISR
2020 5-Azacytidine inhaled dry powder formulation profoundly improves pharmacokinetics and efficacy for lung cancer therapy through genome reprogramming. ---
2020 Altered ARID1A expression in colorectal cancer. ---
2020 Combination of 5-azaytidine and hanging drop culture convert fat cell into cardiac cell. hADSCs, HD
2020 Direct Conversion of Human Dermal Fibroblasts into Cardiomyocyte-Like Cells Using CiCMC Nanogels Coupled with Cardiac Transcription Factors and a Nucleoside Drug. CMC, NHDFs
2020 DNA Methylation as a Therapeutic Target for Bladder Cancer. BC, DAC, DNMT
2020 DNA methyltransferase inhibitor alleviates bleomycin-induced pulmonary inflammation. ALI, BALF, CBC
2020 Fetal Programming by Methyl Donors Modulates Central Inflammation and Prevents Food Addiction-Like Behavior in Rats. CAF, NAc, SAM
2020 In vitro and in vivo induction of fetal hemoglobin with a reversible and selective DNMT1 inhibitor. DNMT, EPCs
10  2020 Interplay of ERalpha binding and DNA methylation in the intron-2 determines the expression and estrogen regulation of cystatin A in breast cancer cells. ERE
11  2020 Plasma and cerebrospinal fluid pharmacokinetics of the DNA methyltransferase inhibitor, 5-azacytidine, alone and with inulin, in nonhuman primate models. AUC, CSF, ECF, IT-L, ITV, NHP, PK
12  2020 Protective effect of bleomycin on 5-azacitidine induced cytotoxicity and apoptosis in mice hematopoietic stem cells via Bcl-2/Bax and HMGB1 signaling pathway. BLM, HMGB1, HSCs
13  2020 The Thioredoxin-Interacting Protein TXNIP Is a Putative Tumour Suppressor in Cutaneous T-Cell Lymphoma. CTCL, EZH2, TXNIP
14  2020 Transcriptomic Profiles of MV4-11 and Kasumi 1 Acute Myeloid Leukemia Cell Lines Modulated by Epigenetic Modifiers Trichostatin A and 5-Azacytidine. AML, TSA
15  2020 Transdifferentiation of alpha-1,3-galactosyltransferase knockout pig bone marrow derived mesenchymal stem cells into pancreatic beta-like cells by microenvironment modulation. ADMEM, BM-MSCs, GalT-KO, VPA
16  2019 Biomimetic electrical stimulation induces rat bone marrow mesenchymal stem cells to differentiate into cardiomyocyte-like cells via TGF-beta 1 invitro. ACTN2, BMSCs, Cx43, ES, TGF-beta1
17  2019 Comparison of the Cardiomyogenic Potency of Human Amniotic Fluid and Bone Marrow Mesenchymal Stem Cells. AF-MSC, ASA, beta-MHC, BM-MSC, BM-MSC, cTnT
18  2019 Demethylation and epigenetic modification with 5-azacytidine reduces IDH1 mutant glioma growth in combination with temozolomide. 2-HG, GFAP, IDH, PDXs, TMZ, WT
19  2019 Effect of ascorbic acid on differentiation of human amniotic fluid mesenchymal stem cells into cardiomyocyte-like cells. AA, hAF-MSCs, MTT
20  2019 Epigenetic demethylation of sFRPs, with emphasis on sFRP4 activation, leading to Wnt signalling suppression and histone modifications in breast, prostate, and ovary cancer stem cells. CSC, PTM, SFRPs
21  2019 Epigenetic Modifications of the Liver Tumor Cell Line HepG2 Increase Their Drug Metabolic Capacity. EMT, HNF4alpha, PHH
22  2019 Epigenetic therapy of myelodysplastic syndromes connects to cellular differentiation independently of endogenous retroelement derepression. AML, CMML, EREs, HSCs, MDS
23  2019 Generation of new hair cells by DNA methyltransferase (Dnmt) inhibitor 5-azacytidine in a chemically-deafened mouse model. DNMT, OHCs
24  2019 Hyperhomocysteinemia induced endothelial progenitor cells dysfunction through hyper-methylation of CBS promoter. BM, CBS, DNMT1, EPCs, HHcy, HMD
25  2019 Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells. CMV, DAC, DNMTi, DNMTs, EGFP, EMT, UCHL1
26  2019 Identification of predictive factors for overall survival at baseline and during azacitidine treatment in high-risk myelodysplastic syndrome patients treated in the clinical practice. MDS, OS
27  2019 Induction of DNA methyltransferase genes in Helicoverpa armigera following injection of pathogenic bacteria modulates expression of antimicrobial peptides and affects bacterial proliferation. AMPs
28  2019 Infusion of 5-Azacytidine (5-AZA) into the fourth ventricle or resection cavity in children with recurrent posterior Fossa Ependymoma: a pilot clinical trial. AZA, CSF, MRI
29  2019 Tetrahydrocurcumin epigenetically mitigates mitochondrial dysfunction in brain vasculature during ischemic stroke. DNMT1, ECM, I/R, MCAO, MMP-9, THC, tHcy, TIMP-2
30  2019 Transcription factor Tbx5 promotes cardiomyogenic differentiation of cardiac fibroblasts treated with 5-azacytidine. CFs
31  2019 [Expression and prognosis effect of methylation-regulated SLIT3 and SPARCL1 genes in smoking-related lung adenocarcinoma]. LUAD, qPCR
32  2018 5-Aza Exposure Improves Reprogramming Process Through Embryoid Body Formation in Human Gingival Stem Cells. EBs, hGMSCs
33  2018 5-Azacitidine Exerts Prolonged Pro-Apoptotic Effects and Overcomes Cisplatin-Resistance in Non-Seminomatous Germ Cell Tumor Cells. GCTs
34  2018 Differential expression of IL-6/IL-6R and MAO-A regulates invasion/angiogenesis in breast cancer. IDC, MAO
35  2018 Differentiation of brown adipose-derived stem cells into cardiomyocyte-like cells is regulated by a combination of low 5-azacytidine concentration and bone morphogenetic protein 4. ADSCs, BMP4, ERK, rbADSCs
36  2018 Differentiation Therapy by Epigenetic Reconditioning Exerts Antitumor Effects on Liver Cancer Cells. DNMT1, HCC
37  2018 Epigenetic reprogramming using 5-azacytidine promotes an anti-cancer response in pancreatic adenocarcinoma cells. DNMT, GEM, OCT, PDAC, SST, SSTR2
38  2018 Fibrin scaffold could promote survival of the human adipose-derived stem cells during differentiation into cardiomyocyte-like cells. hADSCs
39  2018 Increased cytomegalovirus replication by 5-Azacytidine and viral-induced cytoplasmic expression of DNMT‑1 in medulloblastoma and endothelial cells. HCMV, HUVECs, MBs
40  2018 Insulin-like growth factor-1-mediated regulation of miR-193a expression promotes the migration and proliferation of c-kit-positive mouse cardiac stem cells. CCK-8, CSCs, DNMTs, IGF, PI3K, qPCR
41  2018 Interleukin-17 promotes the production of underglycosylated IgA1 in DAKIKI cells. CCK-8, HAA, IgAN, IL-17, LPS
42  2018 Loss of myogenic potential and fusion capacity of muscle stem cells isolated from contractured muscle in children with cerebral palsy. CP, ITGB1D, TD
43  2018 Pharmacologically upregulated carcinoembryonic antigen-expression enhances the cytolytic activity of genetically-modified chimeric antigen receptor NK-92MI against colorectal cancer cells. CAR, CEA, E/T, HDAC
44  2018 Phase I study of panobinostat and 5-azacitidine in Japanese patients with myelodysplastic syndrome or chronic myelomonocytic leukemia. AE, CMML, MDS, PAN
45  2018 Re-Expression of Bone Marrow Proteoglycan-2 by 5-Azacytidine is associated with STAT3 Inactivation and Sensitivity Response to Imatinib in Resistant CML Cells TSG
46  2018 RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia. RNA, TFs
47  2018 The outcome of patients with high-risk MDS achieving stable disease after treatment with 5-azacytidine: A retrospective analysis of the Hellenic (Greek) MDS Study Group. AML, IPSS, MDS, OS, SD
48  2017 5-Azacytidine-mediated hMSC behavior on electrospun scaffolds for skeletal muscle regeneration. hMSC, PCL
49  2017 Anti-oxidative and anti-inflammatory benefits of the ribonucleoside analogue 5-azacitidine in mice with acetaminophen-induced toxic hepatitis. AST, IL-6, MDA, MPO, NO, TNF-alpha
50  2017 Cell-autonomous cytotoxicity of type I interferon response via induction of endoplasmic reticulum stress. 4-PBA, CHOP, CPX, ER, TUDCA
51  2017 Decoupling of DNA methylation and activity of intergenic LINE-1 promoters in colorectal cancer. L1-ASP, LCT
52  2017 Demethylation Therapy as a Targeted Treatment for Human Papillomavirus-Associated Head and Neck Cancer. HNSCC, MMP
53  2017 Dietary fatty acids modulate adipocyte TNFa production via regulation of its DNA promoter methylation levels. TNFA
54  2017 Differentiation of mesenchymal stem cells into cardiomyocytes is regulated by miRNA-1-2 via WNT signaling pathway. BMSCs
55  2017 Distinct roles and differential expression levels of Wnt5a mRNA isoforms in colorectal cancer cells. CRC
56  2017 Enhanced cardiomyogenic induction of mouse pluripotent cells by cyclic mechanical stretch. CMs, EBs
57  2017 Expression of markers for germ cells and oocytes in cow dermal fibroblast treated with 5-azacytidine and cultured in differentiation medium containing BMP2, BMP4 or follicular fluid. ---
58  2017 Potential of VEGF-encapsulated electrospun nanofibers for in vitro cardiomyogenic differentiation of human mesenchymal stem cells. hMSCs, MI, MSCs, PCL-gelatin, PG, VEGF
59  2017 Successful 5-azacytidine treatment of myeloid sarcoma and leukemia cutis associated with myelodysplastic syndrome: A case report and literature review. AML, HSCT, LC, MDS, MS
60  2017 Synthesis of secondary metabolites by Cladosporium resinae (NRL-6437) under different growth media and chemical inducers and their pharmaceutical activity. CB, CYB, PDB, SAHA, YES
61  2017 The effects of the DNA methyltranfserases inhibitor 5-Azacitidine on ageing, oxidative stress and DNA methylation of adipose derived stem cells. DNMT, MSCs, ROS
62  2017 The role of epigenetic modifiers in extended cultures of functional hepatocyte-like cells derived from human neonatal mesenchymal stem cells. DMSO, HLCs, hnMSCs, hpHeps, TSA
63  2017 Treatment of Myocardial Infarction with Gene-modified Mesenchymal Stem Cells in a Small Molecular Hydrogel. HGF, MI, MSCs, SMH
64  2017 Valproic acid enforces the priming effect of sphingosine-1 phosphate on human mesenchymal stem cells. MSCs, S1P, SDF-1, UC-MSCs, VPA
65  2017 Valproic Acid Induces Decreased Expression of H19 Promoting Cell Apoptosis in A549 Cells. VPA
66  2017 [Regulation and mechanism of miR-148a on cardiomyocyte differentiation induced by 5-aza in mesenchymal stem cells]. DNMT1, hMSCs
67  2016 Adipose-derived stem cells seeded on polyglycolic acid for the treatment of stress urinary incontinence. ADSCs, GFP, LPP, PGA, SUI
68  2016 Antagonist effect of Interleukin 1 receptor on normal thymopoiesis and thymus toxicity of 5-azacytidine in mouse. DN, DP, IL-1, IL-1ra
69  2016 Carcinoembryonic Antigen Expression and Resistance to Radiation and 5-Fluorouracil-Induced Apoptosis and Autophagy. 5-FU, CEA, HDAC
70  2016 Combination of retinoic acid, dimethyl sulfoxide and 5-azacytidine promotes cardiac differentiation of human fetal liver-derived mesenchymal stem cells. DMSO, HFMSCs, MSCs, RA
71  2016 Defective DNA methylation in salivary gland epithelial acini from patients with Sjogren's syndrome is associated with SSB gene expression, anti-SSB/LA detection, and lymphocyte infiltration. Ab, HSG, MSG, MSRE, pSS
72  2016 Differentiation of Bone Marrow Mesenchymal Stem Cells to Cardiomyocyte-Like Cells Is Regulated by the Combined Low Dose Treatment of Transforming Growth Factor-beta1 and 5-Azacytidine. BM-MSCs, TGF-beta1
73  2016 DNA Methyltransferase Inhibitor Promotes Human CD4+CD25hFOXP3+ Regulatory T Lymphocyte Induction under Suboptimal TCR Stimulation. IFN, TCR, TGF, Treg, TSDR
74  2016 DNMT1 Regulates Epithelial-Mesenchymal Transition and Cancer Stem Cells, Which Promotes Prostate Cancer Metastasis. CSCs, DNMT1, EMT, PCa
75  2016 Effect of 5-azacytidine on miRNA expression in human breast cancer cells with different sensitivity to cytostatics. ---
76  2016 Epigenetic DNA Demethylation Causes Inner Ear Stem Cell Differentiation into Hair Cell-Like Cells. DNMT, MUCs
77  2016 Epigenetic Induction of Definitive and Pancreatic Endoderm Cell Fate in Human Fibroblasts. CRM, DNMTi, HDACi, TFs, TSA
78  2016 Epigenetic Therapy for the Treatment of Hypertension-Induced Cardiac Hypertrophy and Fibrosis. SHR
79  2016 Hypermethylation of CpG sites at the promoter region is associated with deregulation of mitochondrial ATPsyn-beta and chemoresistance in acute myeloid leukemia. AML
80  2016 Hypoxia-Induced Changes in DNA Methylation Alter RASAL1 and TGFbeta1 Expression in Human Trabecular Meshwork Cells. COL1A1, DNMT1, GTM, RASAL1, TGF, TM
81  2016 Modifying effects of 5-azacytidine on metal-containing proteins profile in Guerin carcinoma with different sensitivity to cytostatics. ---
82  2016 Rehmannia glutinosa oligosaccharide induces differentiation of bone marrow mesenchymal stem cells into cardiomyocyte-like cells. CK, CK-MB, cTnI, Cx43, MSCs, RGO
83  2016 Role of growth media and chemical enhancers in secondary metabolites production from Aspergillus carbonarius (NRL-369) and their pharmaceutical potentials. SAHA
84  2016 Silencing of miR-1247 by DNA methylation promoted non-small-cell lung cancer cell invasion and migration by effects of STMN1. miRNAs, NSCLC, STMN1
85  2016 Synergistic induction of cardiomyocyte differentiation from human bone marrow mesenchymal stem cells by interleukin 1beta and 5-azacytidine. IL-1beta, MSCs, qPCR
86  2016 Transcriptional activity of acetylcholinesterase gene is regulated by DNA methylation during C2C12 myogenesis. AChE
87  2016 Treatment with 5-Azacytidine improves clinical outcome in high-risk MDS patients in the 'real life' setting: A single center observational study. CR, DeltaWPSS, EFS, HI, MDS, ORR, OS, PD, PR, SD
88  2016 Vitamin C enhances epigenetic modifications induced by 5-azacytidine and cell cycle arrest in the hepatocellular carcinoma cell lines HLE and Huh7. 5hmC, EMT, HCC, IF, LDH, PCNA, TET
89  2015 Aberrant Hypermethylation of SALL3 with HPV Involvement Contributes to the Carcinogenesis of Cervical Cancer. SALL3
90  2015 Beneficial Effects of Hypoxic Preconditioning on Human Umbilical Cord Mesenchymal Stem Cells. HP, hUCMSCs, SP, TnI
91  2015 DNA methyltransferase inhibition accelerates the immunomodulation and migration of human mesenchymal stem cells. DNMT, hMSCs
92  2015 Enhancing SHP-1 expression with 5-azacytidine may inhibit STAT3 activation and confer sensitivity in lestaurtinib (CEP-701)-resistant FLT3-ITD positive acute myeloid leukemia. AML, SH2
93  2015 Expression and significance of DLL4--Notch signaling pathway in the differentiation of human umbilical cord derived mesenchymal stem cells into cardiomyocytes induced by 5-azacytidine. ---
94  2015 Hypomethylation and up-regulation of PD-1 in T cells by azacytidine in MDS/AML patients: A rationale for combined targeting of PD-1 and DNA methylation. HMAs, MDS
95  2015 Imprint of 5-azacytidine on the natural killer cell repertoire during systemic treatment for high-risk myelodysplastic syndrome. KIR, MDS, NK
96  2015 Induction of active demethylation and 5hmC formation by 5-azacytidine is TET2 dependent and suggests new treatment strategies against hepatocellular carcinoma. HCC, hHeps, siRNAs, TET
97  2015 Metabolite diversity in the plant pathogen Alternaria brassicicola: factors affecting production of brassicicolin A, depudecin, phomapyrone A and other metabolites. SAHA, SBHA
98  2015 Porous, Ventricular Extracellular Matrix-Derived Foams as a Platform for Cardiac Cell Culture. DLV, ECM, MCM, pfASCs
99  2015 The DNA methylation inhibitor induces telomere dysfunction and apoptosis of leukemia cells that is attenuated by telomerase over-expression. AML, DNMTis, TERT
100  2015 The effect of two nucleoside antitumor drugs on the proliferation and DNA methylation of human gastric cancer cells. hGCCs