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■ Abbreviation / Long Form : ACT / adenylate cyclase toxin

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Total Number of Papers: 55
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Abbreviation:   ACT  (>> Co-occurring Abbreviation)
Long Form:   adenylate cyclase toxin
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No. Year Title Co-occurring Abbreviation
2018 Evaluation of Adenylate Cyclase Toxoid Antigen in Acellular Pertussis Vaccines by Using a Bordetella pertussis Challenge Model in Mice. RTX, wP
2018 Nucleobase Modified Adefovir (PMEA) Analogues as Potent and Selective Inhibitors of Adenylate Cyclases from Bordetella pertussis and Bacillus anthracis. ANPs, EF, mACs
2018 Synthesis of alpha-Branched Acyclic Nucleoside Phosphonates as Potential Inhibitors of Bacterial Adenylate Cyclases. ANPs, EF
2017 Albumin, in the Presence of Calcium, Elicits a Massive Increase in Extracellular Bordetella Adenylate Cyclase Toxin. FBS
2017 Bordetella adenylate cyclase toxin interacts with filamentous haemagglutinin to inhibit biofilm formation in vitro. FHA, MCD
2017 Fine Epitope Mapping of Two Antibodies Neutralizing the Bordetella Adenylate Cyclase Toxin. RTX
2017 Modulation of Pertussis and Adenylate Cyclase Toxins by Sigma Factor RpoE in Bordetella pertussis. PT
2017 Understanding the Mechanism of Translocation of Adenylate Cyclase Toxin across Biological Membranes. AC
2017 Use of a Toxin Neutralization Assay To Characterize the Serologic Response to Adenylate Cyclase Toxin after Infection with Bordetella pertussis. ELISA, TNA
10  2016 Adenylate cyclase toxin-mediated delivery of the S1 subunit of pertussis toxin into mammalian cells. PT
11  2016 Design and Synthesis of Fluorescent Acyclic Nucleoside Phosphonates as Potent Inhibitors of Bacterial Adenylate Cyclases. AC, CaM, Cl-ANT-ANPs, EF
12  2015 Adenylate Cyclase Toxin promotes bacterial internalisation into non phagocytic cells. ---
13  2015 Bisamidate Prodrugs of 2-Substituted 9-[2-(Phosphonomethoxy)ethyl]adenine (PMEA, adefovir) as Selective Inhibitors of Adenylate Cyclase Toxin from Bordetella pertussis. ---
14  2015 Review of the neutrophil response to Bordetella pertussis infection. LOS, PTX
15  2015 The Bordetella adenylate cyclase repeat-in-toxin (RTX) domain is immunodominant and elicits neutralizing antibodies. RTX
16  2014 Amidate prodrugs of 9-[2-(phosphonomethoxy)ethyl]adenine as inhibitors of adenylate cyclase toxin from Bordetella pertussis. ---
17  2014 Cyclic AMP-mediated suppression of neutrophil extracellular trap formation and apoptosis by the Bordetella pertussis adenylate cyclase toxin. cAMP, NETs
18  2013 Ca2+ influx and tyrosine kinases trigger Bordetella adenylate cyclase toxin (ACT) endocytosis. Cell physiology and expression of the CD11b/CD18 integrin major determinants of the entry route. ---
19  2013 Calpain-Mediated Processing of Adenylate Cyclase Toxin Generates a Cytosolic Soluble Catalytically Active N-Terminal Domain. AC
20  2013 Quantification of the adenylate cyclase toxin of Bordetella pertussis in vitro and during respiratory infection. NPW
21  2012 Contribution of Bordetella filamentous hemagglutinin and adenylate cyclase toxin to suppression and evasion of interleukin-17-mediated inflammation. FHA, IL-17, TNF-alpha
22  2012 Delivery of Bordetella pertussis adenylate cyclase toxin to target cells via outer membrane vesicles. OMV
23  2012 Identification of a CO2 responsive regulon in Bordetella. FHA
24  2012 Role of CD11b/CD18 in the process of intoxication by the adenylate cyclase toxin of Bordetella pertussis. cAMP
25  2012 Transcriptional regulation of murine IL-33 by TLR and non-TLR agonists. IRF3
26  2011 Adenylate cyclase toxin promotes internalisation of integrins and raft components and decreases macrophage adhesion capacity. ---
27  2011 Cell cycle arrest induced by the bacterial adenylate cyclase toxins from Bacillus anthracis and Bordetella pertussis. ---
28  2010 Bordetella adenylate cyclase toxin promotes calcium entry into both CD11b+ and CD11b- cells through cAMP-dependent L-type-like calcium channels. RTX
29  2010 Selective translocation of the Bordetella pertussis adenylate cyclase toxin across the basolateral membranes of polarized epithelial cells. ---
30  2009 Role of neutrophils in response to Bordetella pertussis infection in mice. PT
31  2008 PACAP27 regulates ciliary function in primary cultures of rat brain ependymal cells. CBF, PACAP
32  2007 Bordetella pertussis adenylate cyclase toxin (ACT) induces cyclooxygenase-2 (COX-2) in murine macrophages and is facilitated by ACT interaction with CD11b/CD18 (Mac-1). COX-2, Mac-1
33  2006 Adenylate cyclase influences filamentous haemagglutinin-mediated attachment of Bordetella pertussis to epithelial alveolar cells. FHA
34  2006 Bordetella bronchiseptica modulates macrophage phenotype leading to the inhibition of CD4+ T cell proliferation and the initiation of a Th17 immune response. TTSS
35  2006 Bordetella pertussis inhibition of interleukin-12 (IL-12) p70 in human monocyte-derived dendritic cells blocks IL-12 p35 through adenylate cyclase toxin-dependent cyclic AMP induction. cAMP, D-cAMP, DC, IL-12, IRF-1, MDDC
36  2006 Immunization with a circumsporozoite epitope fused to Bordetella pertussis adenylate cyclase in conjunction with cytotoxic T-lymphocyte-associated antigen 4 blockade confers protection against Plasmodium berghei liver-stage malaria. CSP, MHC
37  2005 Adenylate cyclase toxin (ACT) from Bordetella hinzii: characterization and differences from ACT of Bordetella pertussis. ---
38  2005 Influence of CR3 (CD11b/CD18) expression on phagocytosis of Bordetella pertussis by human neutrophils. FHA, TNF-alpha
39  2005 Pertussis toxin and adenylate cyclase toxin provide a one-two punch for establishment of Bordetella pertussis infection of the respiratory tract. PT
40  2004 Bordetella type III secretion and adenylate cyclase toxin synergize to drive dendritic cells into a semimature state. BMDCs, DCs, TTSS
41  2004 Determination of serum antibody to Bordetella pertussis adenylate cyclase toxin in vaccinated and unvaccinated children and in children and adults with pertussis. DTP vaccines, ELISA
42  2004 Differential inhibition of adenylyl cyclase isoforms and soluble guanylyl cyclase by purine and pyrimidine nucleotides. EF, MANT, sAC, sGC
43  2004 Membrane restructuring by Bordetella pertussis adenylate cyclase toxin, a member of the RTX toxin family. PE
44  2003 Phagocytosis of Bordetella pertussis incubated with convalescent serum. FHA
45  2002 Developments in reduction and replacement of in vivo toxicity and potency tests for pertussis vaccines. AMPT, HIST
46  2002 Protein kinase A translocation and insulin secretion in pancreatic beta-cells: studies with adenylate cyclase toxin from Bordetella pertussis. GLP-1
47  2001 Acylation of lysine 983 is sufficient for toxin activity of Bordetella pertussis adenylate cyclase. Substitutions of alanine 140 modulate acylation site selectivity of the toxin acyltransferase CyaC. A140G
48  2000 Stimulation of Bordetella pertussis adenylate cyclase toxin intoxication by its hemolysin domain. ---
49  1999 In vivo induction of CTL responses by recombinant adenylate cyclase of Bordetella pertussis carrying multiple copies of a viral CD8(+) T-cell epitope. CTL
50  1999 Suppression of platelet aggregation by Bordetella pertussis adenylate cyclase toxin. cAMP
51  1994 Chemical fatty acylation confers hemolytic and toxic activities to adenylate cyclase protoxin of Bordetella pertussis. ---
52  1994 Haemolytic assay for the detection of adenylate cyclase toxin of Bordetella pertussis. ---
53  1993 Antibodies to Bordetella pertussis adenylate cyclase toxin in neonatal and maternal sera. FHA, PT
54  1993 The adenylate cyclase toxin contributes to the survival of Bordetella pertussis within human macrophages. ---
55  1990 Adenylate cyclase toxin of Bordetella pertussis: production, purification, and partial characterization. cAMP