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■ Abbreviation / Long Form : ADAM17 / ADAM metallopeptidase domain 17

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Total Number of Papers: 18
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Abbreviation:   ADAM17  (>> Co-occurring Abbreviation)
Long Form:   ADAM metallopeptidase domain 17
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No. Year Title Co-occurring Abbreviation
2021 Effects of SARS-CoV-2 on Cardiovascular System: The Dual Role of Angiotensin-Converting Enzyme 2 (ACE2) as the Virus Receptor and Homeostasis Regulator-Review. ACE2, ARBs, ARDS, COVID-19, CVDs, RAS, SARS-CoV-2
2021 Estrogen receptors are linked to angiotensin-converting enzyme 2 (ACE2), ADAM metallopeptidase domain 17 (ADAM-17), and transmembrane protease serine 2 (TMPRSS2) expression in the human atrium: insights into COVID-19. ACE2, TMPRSS2
2020 Negatively charged amino acids in the stalk region of membrane proteins reduce ectodomain shedding. ALCAM, ERBB4
2019 Bone Marrow CX3CL1/Fractalkine is a New Player of the Pro-Angiogenic Microenvironment in Multiple Myeloma Patients. ADAM10, BM, CX3CL1, CX3CR1, ECs, MGUS, MM, SMM, TNF-alpha
2019 IL-6 exhibits both cis- and trans-signaling in osteocytes and osteoblasts, but only trans-signaling promotes bone formation and osteoclastogenesis. IL-6, SOCS3, STAT3
2019 Macrophage MerTK Promotes Liver Fibrosis in Nonalcoholic Steatohepatitis. HSCs, MerTK, NASH
2019 MicroRNA-3163 targets ADAM-17 and enhances the sensitivity of hepatocellular carcinoma cells to molecular targeted agents. HCC, miR-3163
2018 Activation of stimulator of interferon genes (STING) induces ADAM17-mediated shedding of the immune semaphorin SEMA4D. IFN, IRF3, STING, TBK1
2017 Elevated semaphorin5A in systemic lupus erythematosus is in association with disease activity and lupus nephritis. CRP, ELISA, mRNA, PBMC, PLT, qPCR, SEMA5A, SLE, SLEDAI
10  2016 In silico approaches and proportional odds model towards identifying selective ADAM17 inhibitors from anti-inflammatory natural molecules. Rg, RMSD, RMSF, SASA
11  2016 MerTK cleavage limits proresolving mediator biosynthesis and exacerbates tissue inflammation. I/R, MerTK, SPMs
12  2015 Loss of ADAM17 is associated with severe multiorgan dysfunction. ---
13  2014 Acute-phase protein alpha1-anti-trypsin: diverting injurious innate and adaptive immune responses from non-authentic threats. AAT, DAMP, IL
14  2014 MicroRNA-26 family is required for human adipogenesis and drives characteristics of brown adipocytes. ---
15  2013 Angiotensin II downregulates ACE2-mediated enhancement of MMP-2 activity in human cardiofibroblasts. Ang II, AT1R, ERK, HCFs, MMPs, RAS
16  2013 Cleavage of pro-tumor necrosis factor alpha by ADAM metallopeptidase domain 17: a fluorescence-based protease assay cleaves its natural protein substrate. proTNFalpha
17  2013 Effects of tetrandrine on glioma cell malignant phenotype via inhibition of ADAM17. CCK-8, EGFR, PI3K, RT-PCR, Tet
18  2010 ADAM metallopeptidase domain 17 (ADAM17) is naturally processed through major histocompatibility complex (MHC) class I molecules and is a potential immunotherapeutic target in breast, ovarian and prostate cancers. EGFR, HLA, MHC