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[Related PubMed/MEDLINE]
Total Number of Papers: 262
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| No. |
Year |
Title |
Co-occurring Abbreviation |
| 1 |
2023 |
Periostin derived from cancer-associated fibroblasts promotes esophageal squamous cell carcinoma progression via ADAM17 activation. |
CAFs, ESCC, POSTN |
| 2 |
2023 |
Phosphate, calcium, and vitamin D signaling, transport, and metabolism in the endometria of cyclic ewes. |
ATP2B4, CYP24, FGFR2, KL, PTHrP, S100g, sGE, TRPV6, VDR |
| 3 |
2022 |
Acute Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Pregnancy Is Associated with Placental Angiotensin-Converting Enzyme 2 Shedding. |
ACE, COVID, SARS-CoV-2 |
| 4 |
2022 |
ADAM17 regulates the proliferation and extracellular matrix of keloid fibroblasts by mediating the EGFR/ERK signaling pathway. |
alpha-SMA, CTGF, ECM, EGFR, ERK, KFs, qRT-PCR, TGF-beta1 |
| 5 |
2022 |
An ADAM17-Neutralizing Antibody Reduces Inflammation and Mortality While Increasing Viral Burden in a COVID-19 Mouse Model. |
ACE2 |
| 6 |
2022 |
An improved Fuzzy based GWO algorithm for predicting the potential host receptor of COVID-19 infection. |
ACE2, ASGR1, CLEC4M, GLCE, GPR78, GWO, IHC, KREMEN1, MS, NDST2, NRG1, PVR, SARS-CoV-2, TMPRSS2 |
| 7 |
2022 |
Analysis of A Disintegrin and Metalloprotease 17 (ADAM17) Expression as a Prognostic Marker in Ovarian Cancer Patients Undergoing First-Line Treatment Plus Bevacizumab. |
--- |
| 8 |
2022 |
Blockade of the protease ADAM17 ameliorates experimental pancreatitis. |
A17pro, IL, NNK, TNF-alpha, WT |
| 9 |
2022 |
Blocking postsynaptic density-93 binding to C-X3-C motif chemokine ligand 1 promotes microglial phenotypic transformation during acute ischemic stroke. |
CX3CL1 |
| 10 |
2022 |
Cardiomyocyte-specific knockout of ADAM17 ameliorates left ventricular remodeling and function in diabetic cardiomyopathy of mice. |
ACE2, DCM, HIF-1alpha, NRCMs |
| 11 |
2022 |
Downregulation of ADAM17 in pediatric immune thrombocytopenia impairs proplatelet formation. |
GPIbalpha, ITP, p-MLC |
| 12 |
2022 |
Endothelial ADAM17 Expression in the Progression of Kidney Injury in an Obese Mouse Model of Pre-Diabetes. |
HFD, TGF-alpha, TNF-alpha |
| 13 |
2022 |
Examination of IgG Fc Receptor CD16A and CD64 Expression by Canine Leukocytes and Their ADCC Activity in Engineered NK Cells. |
ADCC, NK |
| 14 |
2022 |
Galectin-1 orchestrates an inflammatory tumor-stroma crosstalk in hepatoma by enhancing TNFR1 protein stability and signaling in carcinoma-associated fibroblasts. |
CAFs, Gal-1, HCC, HSCs, PAI-2, sh, TNFR1 |
| 15 |
2022 |
Host Cell Receptors Implicated in the Cellular Tropism of BVDV. |
BVDV, HS, LDL |
| 16 |
2022 |
Immune Responses to IAV Infection and the Roles of L-Selectin and ADAM17 in Lymphocyte Homing. |
HEVs, IAV |
| 17 |
2022 |
Implications of Sm22alpha-Cre expression in keratinocytes and unanticipated inflammatory skin lesion in a model of atherosclerosis. |
HFD, LDLR, SMC |
| 18 |
2022 |
Involvement of shedding induced by ADAM17 on the nitric oxide pathway in hypertension. |
ACE2, MasR, NO |
| 19 |
2022 |
PM2.5 induce the defective efferocytosis and promote atherosclerosis via HIF-1alpha activation in macrophage. |
BMDMs, CIMT, HIF-1alpha, MerTK, sMer, VHL |
| 20 |
2022 |
Regulation of autoimmune disease progression by Pik3ip1 through metabolic reprogramming in T cells and therapeutic implications. |
EAE, HIF1alpha, Pik3ip1 |
| 21 |
2022 |
Repurposing of drugs for combined treatment of COVID-19 cytokine storm using machine learning. |
AT1R, JAK1, ML, STAT3 |
| 22 |
2022 |
Shuttle Transfer of mRNA Transcripts via Extracellular Vesicles From Male Reproductive Tract Cells to the Cumulus-Oocyte Complex in Rabbits (Oryctolagus cuniculus). |
COCs, COX2, EVs, IVM, MDK, mRNA, PB, RT-qPCR, VEGFA |
| 23 |
2022 |
The Autism Spectrum Disorder-Associated Bacterial Metabolite p-Cresol Derails the Neuroimmune Response of Microglial Cells Partially via Reduction of ADAM17 and ADAM10. |
ADAM10, ASD, pCG, PCS |
| 24 |
2022 |
The Role of ADAM17 in Inflammation-Related Atherosclerosis. |
--- |
| 25 |
2022 |
TNF or EGFR inhibition equally block AKI-to-CKD transition: opportunities for etanercept treatment. |
EGFR, PTC, TNF, UUO |
| 26 |
2021 |
A New Inhibitor of ADAM17 Composed of a Zinc-Binding Dithiol Moiety and a Specificity Pocket-Binding Appendage. |
TNF-alpha |
| 27 |
2021 |
Abnormal ADAM17 expression causes airway fibrosis in chronic obstructive asthma. |
alpha-SMA, COA, CTGF, si |
| 28 |
2021 |
Activation of ADAM17 by IL-15 Limits Human NK Cell Proliferation. |
IL-15, NK |
| 29 |
2021 |
ADAM17 and NF-kappaB p65 form a positive feedback loop that facilitates human esophageal squamous cell carcinoma cell viability. |
ESCC |
| 30 |
2021 |
ADAM17 Inhibition Increases the Impact of Cisplatin Treatment in Ovarian Cancer Spheroids. |
OvCa |
| 31 |
2021 |
ADAM17 mediates ectodomain shedding of the soluble VLDL receptor fragment in the retinal epithelium. |
sVLDLR, VLDLR |
| 32 |
2021 |
ADAM17, A Key Player of Cardiac Inflammation and Fibrosis in Heart Failure Development During Chronic Catecholamine Stress. |
AREG, beta-ARs, ERKs, p38 MAPKs, sIL-6R, TNF-alpha |
| 33 |
2021 |
ADAM17/MMP inhibition prevents neutrophilia and lung injury in a mouse model of COVID-19. |
ACE2, COVID-19, NLR, RBD-S |
| 34 |
2021 |
Aging-induced impaired endothelial wall shear stress mechanosensing causes arterial remodeling via JAM-A/F11R shedding by ADAM17. |
WSS |
| 35 |
2021 |
Aryl Hydrocarbon Receptor Defect Attenuates Mitogen-Activated Signaling through Leucine-Rich Repeats and Immunoglobulin-like Domains 1 (LRIG1)-Dependent EGFR Degradation. |
AhR, COPD, EGF, EGFR, LRIG1 |
| 36 |
2021 |
Defective Efferocytosis in a Murine Model of Sjogren's Syndrome Is Mediated by Dysfunctional Mer Tyrosine Kinase Receptor. |
ANA, MerKO, SjS, SjSs, sMer, SMG |
| 37 |
2021 |
Diminazen Aceturate Protects Pulmonary Ischemia-Reperfusion Injury via Inhibition of ADAM17-Mediated Angiotensin-Converting Enzyme 2 Shedding. |
ACE2, DIZE, IR |
| 38 |
2021 |
Functionally confirmed compound heterozygous ADAM17 missense loss-of-function variants cause neonatal inflammatory skin and bowel disease 1. |
NISBD1, TNF-alpha |
| 39 |
2021 |
Hypoxia-induced preadipocyte factor 1 expression in human lung fibroblasts through ERK/PEA3/c-Jun pathway. |
AP-1, ERK, HIF-1alpha, OVA, PEA3, Pref-1, si |
| 40 |
2021 |
Identification of novel substrates of a disintegrin and metalloprotease 17 by specific labeling of surface proteins. |
2-DE |
| 41 |
2021 |
Implications of ADAM17 activation for hyperglycaemia, obesity and type 2 diabetes. |
TNF-alpha |
| 42 |
2021 |
Interactions of renin-angiotensin system and COVID-19: the importance of daily rhythms in ACE2, ADAM17 and TMPRSS2 expression. |
ACE2, Ang II, SARS-CoV-2, TMPRSS2 |
| 43 |
2021 |
iRhom1 rescues cognitive dysfunction in multiple sclerosis via preventing myelin injury. |
MS, OL |
| 44 |
2021 |
KIM-1-mediated anti-inflammatory activity is preserved by MUC1 induction in the proximal tubule during ischemia-reperfusion injury. |
IRI, KIM-1, KO, MUC1, PT, WT |
| 45 |
2021 |
MicroRNA-146a-5p enhances T helper 17 cell differentiation via decreasing a disintegrin and metalloprotease 17 level in primary sjogren's syndrome. |
mIL-23R, miR, PBMCs, pSS, Th17 |
| 46 |
2021 |
MicroRNA‑28‑3p inhibits angiotensin‑converting enzyme2 ectodomain shedding in 293T cells treated with the spike protein of severe acute respiratory syndrome coronavirus2 by targeting A disintegrin and metalloproteinase 17. |
ACE2, miR |
| 47 |
2021 |
OM-85 Broncho-Vaxom, a Bacterial Lysate, Reduces SARS-CoV-2 Binding Proteins on Human Bronchial Epithelial Cells. |
ACE2, DPP4, S protein, TMPRSS2 |
| 48 |
2021 |
Redefining the Role of ADAM17 in Renal Proximal Tubular Cells and Its Implications in an Obese Mouse Model of Pre-Diabetes. |
HFD |
| 49 |
2021 |
Regulation of osteoarthritis development by ADAM17/Tace in articular cartilage. |
DMM, EGFR, Mmp13, OA, PMA, TACE |
| 50 |
2021 |
Regulation of Platelet-Derived ADAM17: A Biomarker Approach for Breast Cancer? |
pADAM17 |
| 51 |
2021 |
Restoration of renal TIMP3 levels via genetics and pharmacological approach prevents experimental diabetic nephropathy. |
DN, NOX4 |
| 52 |
2021 |
Roles for ADAM17 in TNF-R1 Mediated Cell Death and Survival in Human U937 and Jurkat Cells. |
TACE |
| 53 |
2021 |
Rosmarinic acid inhibits proliferation and migration, promotes apoptosis and enhances cisplatin sensitivity of melanoma cells through inhibiting ADAM17/EGFR/AKT/GSK3beta axis. |
CIS, EGFR, RA |
| 54 |
2021 |
Secretases in Alzheimer's disease: Novel insights into proteolysis of APP and TREM2. |
AD, ADAM10, APP, BACE1, TREM2 |
| 55 |
2021 |
Shikonin suppresses colon cancer cell growth and exerts synergistic effects by regulating ADAM17 and the IL‑6/STAT3 signaling pathway. |
eIF2alpha, ROS, SKN, STAT3 |
| 56 |
2021 |
Strategies to Target ADAM17 in Disease: From its Discovery to the iRhom Revolution. |
TNF |
| 57 |
2021 |
Targeted truncation of the ADAM17 cytoplasmic domain in mice results in protein destabilization and a hypomorphic phenotype. |
EGFR, IL-6R, TNF-alpha |
| 58 |
2021 |
The -172 A-to-G variation in ADAM17 gene promoter region affects EGR1/ADAM17 pathway and confers susceptibility to septic mortality with sepsis-3.0 criteria. |
ChIP, Egr-1 |
| 59 |
2021 |
The Downregulation of ADAM17 Exerts Protective Effects against Cardiac Fibrosis by Regulating Endoplasmic Reticulum Stress and Mitophagy. |
ER, mCFs |
| 60 |
2021 |
The Synergy of ADAM17-Induced Myocardial Inflammation and Metabolic Lipids Dysregulation During Acute Stress: New Pathophysiologic Insights Into Takotsubo Cardiomyopathy. |
AHA, beta-ARs, TTC |
| 61 |
2021 |
Titanium dioxide nanoparticles impair the inner blood-retinal barrier and retinal electrophysiology through rapid ADAM17 activation and claudin-5 degradation. |
HRECs |
| 62 |
2021 |
[Effect of active component compound of Epimedii Folium,Astragali Radix,and Puerariae Lobatae Radix on expression of ADAM17 in HT22 cells by mediating hepcidin]. |
AD, APP, siRNA |
| 63 |
2020 |
A Bispecific Inhibitor of the EGFR/ADAM17 Axis Decreases Cell Proliferation and Migration of EGFR-Dependent Cancer Cells. |
DARPin, EGFR |
| 64 |
2020 |
ACE2/ADAM17/TMPRSS2 Interplay May Be the Main Risk Factor for COVID-19. |
ACE2, COVID-19, RAS |
| 65 |
2020 |
Activation of Kinin B1R Upregulates ADAM17 and Results in ACE2 Shedding in Neurons. |
ACE2, ADAM, B1R, LDABK |
| 66 |
2020 |
ADAM17-regulated CX3CL1 expression produced by bone marrow endothelial cells promotes spinal metastasis from hepatocellular carcinoma. |
AKT1, BMECs, CX3CL1, CXCR3, HCC, MAPK, PIK3CA, PTK2, RhoA, ROCK2 |
| 67 |
2020 |
Alpha-1-antitrypsin: A possible host protective factor against Covid-19. |
A1AT, NE, TMPRSS2 |
| 68 |
2020 |
Decreased ADAM17 expression in the lungs of alpha-Klotho reduced mouse. |
SMP30 |
| 69 |
2020 |
Distance dependent shedding of IL-6R. |
PS |
| 70 |
2020 |
Excessive ADAM17 activation occurs in uremic patients and may contribute to their immunocompromised status. |
FGF23, HD, HS |
| 71 |
2020 |
IL-33 promotes type 1 cytokine expression via p38 MAPK in human NK cells. |
--- |
| 72 |
2020 |
Influences of miR-708 on cerebral ischemia-reperfusion injury through targeted regulation of ADAM17. |
MCAO, miR, siRNA |
| 73 |
2020 |
Long noncoding RNA SBF2-AS1 contributes to the growth and metastatic phenotypes of NSCLC via regulating miR-338-3p/ADAM17 axis. |
lncRNA, NSCLC, RIP, SBF2-AS1 |
| 74 |
2020 |
Novel Evidence of Acute Kidney Injury in COVID-19. |
AKI, SARS-CoV-2, TMPRSS2 |
| 75 |
2020 |
Palmatine ameliorates Helicobacter pylori-induced chronic atrophic gastritis by inhibiting MMP-10 through ADAM17/EGFR. |
CAG, H. pylori, HB-EGF, IL-8, Pal |
| 76 |
2020 |
Role of iRhoms 1 and 2 in Endochondral Ossification. |
iRhom1, 2 |
| 77 |
2020 |
Shedding Light on COVID-19: ADAM17 the Missing Link? |
COVID-19 |
| 78 |
2020 |
TGF-beta Induced CTGF Expression in Human Lung Epithelial Cells through ERK, ADAM17, RSK1, and C/EBPbeta Pathways. |
ADAM17-siRNA, CTGF, EMT, ERK, FN, RSK1, TGF-beta |
| 79 |
2019 |
ADAM17-deficiency on microglia but not on macrophages promotes phagocytosis and functional recovery after spinal cord injury. |
SCI |
| 80 |
2019 |
ADAM17-Mediated Reduction in CD14++CD16+ Monocytes ex vivo and Reduction in Intermediate Monocytes With Immune Paresis in Acute Pancreatitis and Acute Alcoholic Hepatitis. |
AAH, AP, LPS, PBMCs, TLR |
| 81 |
2019 |
ADAM17: An Emerging Therapeutic Target for Lung Cancer. |
EGFR, LAC, NSCLC, SCLC, sIL-6R, TNF-alpha |
| 82 |
2019 |
Angiotensin II deteriorates advanced atherosclerosis by promoting MerTK cleavage and impairing efferocytosis through the AT1R/ROS/p38 MAPK/ADAM17 pathway. |
ACS, AT1R, MerTK, NAC, ROS, sMer |
| 83 |
2019 |
Circadian Expression of TIMP3 Is Disrupted by UVB Irradiation and Recovered by Green Tea Extracts. |
AQP3, TNF-alpha, UVB, UVR |
| 84 |
2019 |
Feedback loop in miR-449b-3p/ADAM17/NF-kappaB promotes metastasis in nasopharyngeal carcinoma. |
miRNAs, NPC |
| 85 |
2019 |
KDEL Receptor 1 Contributes to Cell Surface Association of Protein Disulfide Isomerases. |
ER, KDELRs, PDIs |
| 86 |
2019 |
L-selectin shedding affects bacterial clearance in the lung: a new regulatory pathway for integrin outside-in signaling. |
--- |
| 87 |
2019 |
Macrophage metabolic reprogramming aggravates aortic dissection through the HIF1alpha-ADAM17 pathway✰. |
CBA, ChIP, ELISA, HIF-1alpha |
| 88 |
2019 |
Potential role of a disintegrin and metalloproteinase-17 (ADAM17) in age-associated ventricular remodeling of rats. |
TNF-alpha |
| 89 |
2019 |
Proximal Tubule-Derived Amphiregulin Amplifies and Integrates Profibrotic EGF Receptor Signals in Kidney Fibrosis. |
EGFR, YAP1 |
| 90 |
2019 |
Rapid and sensitive detection of the activity of ADAM17 using a graphene oxide-based fluorescence sensor. |
CGO |
| 91 |
2019 |
Role of ADAM17 as a regulatory checkpoint of CD16A in NK cells and as a potential target for cancer immunotherapy. |
ADCC |
| 92 |
2019 |
Rutaecarpine prevents hypertensive cardiac hypertrophy involving the inhibition of Nox4-ROS-ADAM17 pathway. |
AAC, Ang II, ERK, NOX4, ROS |
| 93 |
2019 |
Sema4D expression and secretion are increased by HIF-1alpha and inhibit osteogenesis in bone metastases of lung cancer. |
Sema4D |
| 94 |
2019 |
Soluble delta-like 1 homolog decreases in patients with acromegaly following pituitary surgery: A potential mediator of adipogenesis suppression by growth hormone? |
sDlk1, sKlotho |
| 95 |
2019 |
The metalloprotease ADAM17 in inflammation and cancer. |
EGFR, IL-6R, TNF-alpha |
| 96 |
2019 |
TMEM16F inhibition limits pain-associated behavior and improves motor function by promoting microglia M2 polarization in mice. |
SCI, TMEM16F |
| 97 |
2018 |
A novel inhibitor of ADAM17 sensitizes colorectal cancer cells to 5-Fluorouracil by reversing Notch and epithelial-mesenchymal transition in vitro and in vivo. |
EMT |
| 98 |
2018 |
A protective Langerhans cell-keratinocyte axis that is dysfunctional in photosensitivity. |
DTA, EGFR, LC, SLE, UVR |
| 99 |
2018 |
A Reduction in ADAM17 Expression Is Involved in the Protective Effect of the PPAR-alpha Activator Fenofibrate on Pressure Overload-Induced Cardiac Hypertrophy. |
HW/BW, LVAW, LVPW, LVW/BW, PPAR-alpha |
| 100 |
2018 |
ADAM17 inhibition enhances platinum efficiency in ovarian cancer. |
AREG, EGFR, ERK, PMA |
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