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■ Abbreviation / Long Form : APP / APPswe

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Total Number of Papers: 31
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Abbreviation:   APP  (>> Co-occurring Abbreviation)
Long Form:   APPswe
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No. Year Title Co-occurring Abbreviation
2019 Dl-3-n-Butylphthalide Inhibits NLRP3 Inflammasome and Mitigates Alzheimer's-Like Pathology via Nrf2-TXNIP-TrX Axis. AD, Dl-NBP, NLRP3, Nrf2, TrX, TXNIP
2018 A role for APP in Wnt signalling links synapse loss with beta-amyloid production. AD, DKK1
2018 APP promotes osteoblast survival and bone formation by regulating mitochondrial function and preventing oxidative stress. AD, NAC, OB, ROS
2018 Endosomal-Lysosomal Cholesterol Sequestration by U18666A Differentially Regulates Amyloid Precursor Protein (APP) Metabolism in Normal and APP-Overexpressing Cells. EL, FBS
2016 Generation of aggregation prone N-terminally truncated amyloid beta peptides by meprin beta depends on the sequence specificity at the cleavage site. AD, KO
2015 Differential regulation of the high-affinity choline transporter by wild-type and Swedish mutant amyloid precursor protein. CHT
2015 Nicorandil inhibits oxidative stress and amyloid-beta precursor protein processing in SH-SY5Y cells overexpressing APPsw. AD
2013 Effects of nicorandil in neuroprotective activation of PI3K/AKT pathways in a cellular model of Alzheimer's disease. ---
2013 Hypoxia-triggered m-calpain activation evokes endoplasmic reticulum stress and neuropathogenesis in a transgenic mouse model of Alzheimer's disease. AD, ER, GSK3beta, UPR
10  2013 Swedish mutant APP suppresses osteoblast differentiation and causes osteoporotic deficit, which are ameliorated by N-acetyl-L-cysteine. AD, BMSCs, NAC, OBs, OCN, OCs, ROS
11  2012 Ginsenoside Rg1 promotes nonamyloidgenic cleavage of APP via estrogen receptor signaling to MAPK/ERK and PI3K/Akt. AD, ER, ERK/MAPK, PI3K, PKC, sAPPalpha
12  2012 Low PiB PET retention in presence of pathologic CSF biomarkers in Arctic APP mutation carriers. eoFAD, FDG, HCs, PiB, PSEN1, SAD
13  2011 APPswe/Abeta regulation of osteoclast activation and RAGE expression in an age-dependent manner. AD, BMMs, OC, RAGE, sRAGE
14  2011 Suppression of Alzheimer's disease-related phenotypes by expression of heat shock protein 70 in mice. AD
15  2010 beta-Secretase inhibitor potency is decreased by aberrant beta-cleavage location of the "Swedish mutant" amyloid precursor protein. AD, BSIs
16  2010 Increased amyloidogenic processing of transgenic human APP in X11-like deficient mouse brain. X11L, X11L2
17  2009 Allele-specific RNAi mitigates phenotypic progression in a transgenic model of Alzheimer's disease. AD, rAAV, RNAi, shRNA, tRNA
18  2009 alpha-secretase mediated conversion of the amyloid precursor protein derived membrane stub C99 to C83 limits Abeta generation. ---
19  2009 Effect of amyloid beta on capacitive calcium entry in neural 2a cells. CCE
20  2009 Oxidative stress induces macroautophagy of amyloid beta-protein and ensuing apoptosis. AD
21  2007 Endoplasmic reticulum chaperones inhibit the production of amyloid-beta peptides. AD, ER, GRP78
22  2006 Effects of endogenous beta-amyloid overproduction on tau phosphorylation in cell culture. cdk-5, GSK-3, PHF, PKC
23  2006 Fermented papaya preparation attenuates beta-amyloid precursor protein: beta-amyloid-mediated copper neurotoxicity in beta-amyloid precursor protein and beta-amyloid precursor protein Swedish mutation overexpressing SH-SY5Y cells. AD, FPP, NO, ROS
24  2006 Induction of silencing effect of Swedish mutant amyloid precursor protein by RNA interference. GFP, siRNAs
25  2006 Nicotine attenuates beta-amyloid-induced neurotoxicity by regulating metal homeostasis. AD
26  2004 Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase. AD, FAD
27  2001 The protease inhibitor, MG132, blocks maturation of the amyloid precursor protein Swedish mutant preventing cleavage by beta-Secretase. AEBSF
28  1994 Calcium and neuronal injury in Alzheimer's disease. Contributions of beta-amyloid precursor protein mismetabolism, free radicals, and metabolic compromise. AD, Ca
29  1994 Secreted forms of beta-amyloid precursor protein protect against ischemic brain injury. ---
30  1994 Secreted forms of beta-amyloid precursor protein protect hippocampal neurons against amyloid beta-peptide-induced oxidative injury. ---
31  1993 Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein. ---