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■ Abbreviation / Long Form : AREs / AU-rich elements

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Total Number of Papers: 238
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Abbreviation:   AREs  (>> Co-occurring Abbreviation)
Long Form:   AU-rich elements
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No. Year Title Co-occurring Abbreviation
2019 A natural "GA" insertion mutation in the sequence encoding the 3'UTR of CXCL12/SDF-1alpha: Identification, characterization, and functional impact on mRNA splicing. MTI
2019 Bi-phased regulation of the post-transcriptional inflammatory response by Tristetraprolin levels. TTP
2019 Oncolytic potential of an E4-deficient adenovirus that can recognize the stabilization of AU-rich element containing mRNA in cancer cells. ELAV
2019 RNA-binding proteins distinguish between similar sequence motifs to promote targeted deadenylation by Ccr4-Not. PREs
2019 The 3'UTR of human MAVS mRNA contains multiple regulatory elements for the control of protein expression and subcellular localization. MAVS, VSV
2019 The ELAV family of RNA-binding proteins in synaptic plasticity and long-term memory. RBPs
2019 The KH-type splicing regulatory protein (KSRP) regulates type III interferon expression post-transcriptionally. 3'-UTR, IFNL3, IFNs, KSRP
2019 Tristetraprolin specifically regulates the expression and alternative splicing of immune response genes in HeLa cells. TTP
2018 ARE-mediated decay controls gene expression and cellular metabolism upon oxygen variations. AMD
10  2018 AUF1 modulates TGF-beta signal in renal tubular epithelial cells via post-transcriptional regulation of Nedd4L expression. UUO
11  2018 MiR-155-5p controls colon cancer cell migration via post-transcriptional regulation of Human Antigen R (HuR). CRC, HuR
12  2018 Post-transcriptional regulation of cytokine expression and signaling. GREs
13  2018 Translational repression of pre-formed cytokine-encoding mRNA prevents chronic activation of memory T cells. 3'UTR
14  2018 Yeast Cth2 protein represses the translation of ARE-containing mRNAs in response to iron deficiency. CTD, NTD, TZF
15  2017 3'-UTR SNP rs2229611 in G6PC1 affects mRNA stability, expression and Glycogen Storage Disease type-Ia risk. GSD-Ia, LD
16  2017 3'UTR AU-Rich Elements (AREs) and the RNA-Binding Protein Tristetraprolin (TTP) Are Not Required for the LPS-Mediated Destabilization of Phospholipase-Cbeta-2 mRNA in Murine Macrophages. LPS, PLCbeta-2, TTP, WT
17  2017 A novel mechanism for variable phenotypic expressivity in Mendelian diseases uncovered by an AU-rich element (ARE)-creating mutation. ARE
18  2017 ACTH Action on Messenger RNA Stability Mechanisms. RNA-BP
19  2017 Hallmarks of cancer and AU-rich elements. ---
20  2017 Hsp70's RNA-binding and mRNA-stabilizing activities are independent of its protein chaperone functions. ---
21  2017 Inflammation-regulated mRNA stability and the progression of vascular inflammatory diseases. RBPs
22  2017 KSRP suppresses cell invasion and metastasis through miR-23a-mediated EGR3 mRNA degradation in non-small cell lung cancer. KSRP, NSCLC
23  2017 Post-transcriptional regulation of cytokine and growth factor signaling in cancer. GREs
24  2017 PTEN expression is upregulated by a RNA-binding protein RBM38 via enhancing its mRNA stability in breast cancer. 3'-UTR, PI3K, RBM38, RBP, siRNA
25  2017 RNA Binding Protein Regulation and Cross-Talk in the Control of AU-rich mRNA Fate. PTMs, RBPs
26  2017 RNPC1 enhances progesterone receptor functions by regulating its mRNA stability in breast cancer. 3'-UTR, PR, RNPC1
27  2017 The role of c-Myc-RBM38 loop in the growth suppression in breast cancer. 3'-UTR, RBPs, RRM
28  2016 Genome-wide identification of Wig-1 mRNA targets by RIP-Seq analysis. RBPs, RIP-Seq
29  2016 Impact of HuR inhibition by the small molecule MS-444 on colorectal cancer cell tumorigenesis. CRC
30  2016 Induction of Glucocorticoid-induced Leucine Zipper (GILZ) Contributes to Anti-inflammatory Effects of the Natural Product Curcumin in Macrophages. GILZ
31  2016 Interrogating the degradation pathways of unstable mRNAs with XRN1-resistant sequences. mRNAs, NMD, xrFrag
32  2016 Negative Feed-forward Control of Tumor Necrosis Factor (TNF) by Tristetraprolin (ZFP36) Is Limited by the Mitogen-activated Protein Kinase Phosphatase, Dual-specificity Phosphatase 1 (DUSP1): IMPLICATIONS FOR REGULATION BY GLUCOCORTICOIDS. DUSP1, IL1B, TNF, ZFP36
33  2016 Recruitment of the 4EHP-GYF2 cap-binding complex to tetraproline motifs of tristetraprolin promotes repression and degradation of mRNAs with AU-rich elements. MEFs, TTP
34  2016 Targeted mRNA Decay by RNA Binding Protein AUF1 Regulates Adult Muscle Stem Cell Fate, Promoting Skeletal Muscle Integrity. ---
35  2016 The MK2/HuR signaling pathway regulates TNF-alpha-induced ICAM-1 expression by promoting the stabilization of ICAM-1 mRNA. ActD, ALI, ARDS, HPMECs, HuR, ICAM-1, IL-8, MAPK, TNF-alpha
36  2015 Deletion of AU-rich elements within the Bcl2 3'UTR reduces protein expression and B cell survival in vivo. 3'UTR, RBPs
37  2015 Exercise, skeletal muscle and inflammation: ARE-binding proteins as key regulators in inflammatory and adaptive networks. ---
38  2015 Expression of leukemia inhibitory factor in Muller glia cells is regulated by a redox-dependent mRNA stability mechanism. ILF3, KHSRP, LIF
39  2015 Identification of novel post-transcriptional features in olfactory receptor family mRNAs. Olfr, uORFs
40  2015 Identification of Small-Molecule Inhibitors of the HuR/RNA Interaction Using a Fluorescence Polarization Screening Assay Followed by NMR Validation. HTS, HuR, STD, UTR
41  2015 Integrin alpha3beta1 signaling through MEK/ERK determines alternative polyadenylation of the MMP-9 mRNA transcript in immortalized mouse keratinocytes. 3'-UTR, ERK, MAPK, MMP-9, SCC
42  2015 PARN deadenylase is involved in miRNA-dependent degradation of TP53 mRNA in mammalian cells. 3'UTRs, Ago-2, miRISC, miRNA, PARN
43  2015 Proteomics and Transcriptomics of BJAB Cells Expressing the Epstein-Barr Virus Noncoding RNAs EBER1 and EBER2. EBV
44  2015 Resveratrol Induces Glioma Cell Apoptosis through Activation of Tristetraprolin. TTP
45  2015 Viral activation of stress-regulated Rho-GTPase signaling pathway disrupts sites of mRNA degradation to influence cellular gene expression. ECs, KSHV, PBs
46  2014 CNOT7/hCAF1 is involved in ICAM-1 and IL-8 regulation by tristetraprolin. 3'-UTR, HPMEC, ICAM-1, IL-8, TNF-alpha, TTP
47  2014 Control of pro-angiogenic cytokine mRNA half-life in cancer: the role of AU-rich elements and associated proteins. TTP
48  2014 hnRNP F complexes with tristetraprolin and stimulates ARE-mRNA decay. RBPs
49  2014 Mutational and structural analysis of the tandem zinc finger domain of tristetraprolin. TNF, TTP, TZF, UTRs
50  2014 Physiological networks and disease functions of RNA-binding protein AUF1. 3'-UTR, AUBP, HNRNPD, mRNA
51  2014 Post-transcriptional regulation of cytokine signaling by AU-rich and GU-rich elements. GREs
52  2014 Post-transcriptional up-regulation of PDGF-C by HuR in advanced and stressed breast cancer. 3'-UTR, PDGF-C, pTNM
53  2014 Posttranscriptional control of the chemokine receptor CXCR4 expression in cancer cells. 3'-UTR, mRNA
54  2014 Reduction of TLR4 mRNA stability and protein expressions through inhibiting cytoplasmic translocation of HuR transcription factor by E₂ and/or ERalpha in LPS-treated H9c2 cardiomyoblast cells. 3'UTR, AUF1, Dox, ERalpha, HuR, LPS, TLR4, TNF-alpha, TTP
55  2014 Sustained stabilization of Interleukin-8 mRNA in human macrophages. ---
56  2014 The Arabidopsis thaliana tandem zinc finger 1 (AtTZF1) protein in RNA binding and decay. AtTZF1
57  2014 The Drosophila Tis11 protein and its effects on mRNA expression in flies. ---
58  2014 Translational regulation of specific mRNAs controls feedback inhibition and survival during macrophage activation. LPS
59  2014 Wig-1 regulates cell cycle arrest and cell death through the p53 targets FAS and 14-3-3sigma. si
60  2013 A novel high throughput biochemical assay to evaluate the HuR protein-RNA complex formation. ---
61  2013 Activation of p38 signaling increases utrophin A expression in skeletal muscle via the RNA-binding protein KSRP and inhibition of AU-rich element-mediated mRNA decay: implications for novel DMD therapeutics. DMD
62  2013 Crustacean hyperglycemic hormone precursor transcripts in the hemocytes of the crayfish Procambarus clarkii: novel sequence characteristics relating to gene splicing pattern and transcript stability. CHH
63  2013 DEAD box protein DDX1 regulates cytoplasmic localization of KSRP. ARE-BPs, KSRP
64  2013 Hsp27 and F-box protein beta-TrCP promote degradation of mRNA decay factor AUF1. MAP
65  2013 Hsp70 is a novel posttranscriptional regulator of gene expression that binds and stabilizes selected mRNAs containing AU-rich elements. 3'UTRs, VEGF
66  2013 Involvement of post-transcriptional regulation of FOXO1 by HuR in 5-FU-induced apoptosis in breast cancer cells. 5-FU, FOXO, HuR, UTR
67  2013 Multiple functions of the RNA-binding protein HuR in cancer progression, treatment responses and prognosis. ---
68  2013 Negative feedback regulation of the yeast CTH1 and CTH2 mRNA binding proteins is required for adaptation to iron deficiency and iron supplementation. 3'UTRs
69  2013 Nucleolin mediates microRNA-directed CSF-1 mRNA deadenylation but increases translation of CSF-1 mRNA. miRNA, PABPC, RRMs
70  2013 Protein segregase meddles in remodeling of mRNA-protein complexes. ---
71  2013 Regulation of ARE-mRNA Stability by Cellular Signaling: Implications for Human Cancer. ---
72  2013 Structural basis for the recruitment of the human CCR4-NOT deadenylase complex by tristetraprolin. TTP
73  2013 The structure of the ARE-binding domains of Hu antigen R (HuR) undergoes conformational changes during RNA binding. FPA, HuR, HuR, RRM
74  2012 Altered stability of mRNAs associated with glaucoma progression in human trabecular meshwork cells following oxidative stress. HTM, HuR, MMP
75  2012 AU-rich element-mediated mRNA decay can occur independently of the miRNA machinery in mouse embryonic fibroblasts and Drosophila S2-cells. ---
76  2012 AU-rich elements in the 3'-UTR regulate the stability of the 141 amino acid isoform of parathyroid hormone-related protein mRNA. PTHrP, TTP
77  2012 AU-rich-element-dependent translation repression requires the cooperation of tristetraprolin and RCK/P54. TNF-alpha, TTP, UTR
78  2012 AUF1/hnRNP D is a novel protein partner of the EBER1 noncoding RNA of Epstein-Barr virus. AUF1, EBER, EBV, SILAC, UTR
79  2012 Characterization of 3'-untranslated region of the mouse GDNF gene. 3'-UTR, GDNF
80  2012 Control of cytokine mRNA expression by RNA-binding proteins and microRNAs. 3'UTRs
81  2012 Drosophila eyes absent is a novel mRNA target of the tristetraprolin (TTP) protein DTIS11. eya, EYA2, TTP
82  2012 Evaluating posttranscriptional regulation of cytokine genes. UTR
83  2012 Genome-wide assessment of AU-rich elements by the AREScore algorithm. UTR
84  2012 HuR post-transcriptionally regulates TNF-alpha-induced IL-6 expression in human pulmonary microvascular endothelial cells mainly via tristetraprolin. 3'-UTRs, HPMECs, IL-6, RIP, TNF-alpha, TTP
85  2012 HuR posttranscriptionally regulates early growth response-1 (Egr-1) expression at the early stage of T cell activation. Egr-1, mRNP
86  2012 HuR protein attenuates miRNA-mediated repression by promoting miRISC dissociation from the target RNA. 3'-UTR, miRNA
87  2012 Kaposi's sarcoma-associated herpesvirus G-protein-coupled receptor prevents AU-rich-element-mediated mRNA decay. KSHV, PBs, vGPCR
88  2012 MK2 posttranscriptionally regulates TNF-alpha-induced expression of ICAM-1 and IL-8 via tristetraprolin in human pulmonary microvascular endothelial cells. 3'-UTR, HPMECs, ICAM-1, IL-8, MAPK, TNF-alpha, TTP
89  2012 Roles of promoter and 3' untranslated motifs in expression of the human C5a receptor. C5aR, EGFP, GPCR, UTR
90  2012 The mRNA-binding protein Zfp36 is upregulated by beta-adrenergic stimulation and represses IL-6 production in 3T3-L1 adipocytes. 3'-UTR, cAMP, DEX, IL-6, ISO, LPS, RA, Zfp36
91  2012 The protein Zfand5 binds and stabilizes mRNAs with AU-rich elements in their 3'-untranslated regions. ---
92  2012 Tristetraprolin impairs myc-induced lymphoma and abolishes the malignant state. AUBPs
93  2011 Chenodeoxycholic acid stabilization of LDL receptor mRNA depends on 3'-untranslated region and AU-rich element-binding protein. 3'-UTR, CDCA, LDLR, MAPK
94  2011 Different modes of interaction by TIAR and HuR with target RNA and DNA. RRMs
95  2011 Global assessment of GU-rich regulatory content and function in the human transcriptome. GREs
96  2011 Interleukin-1 activates synthesis of interleukin-6 by interfering with a KH-type splicing regulatory protein (KSRP)-dependent translational silencing mechanism. IL, KH, KSRP
97  2011 Not1 mediates recruitment of the deadenylase Caf1 to mRNAs targeted for degradation by tristetraprolin. CCR4, mRNA, TTP
98  2011 Phosphorylation of tristetraprolin by MK2 impairs AU-rich element mRNA decay by preventing deadenylase recruitment. MAPK, TTP
99  2011 Post-transcriptional gene regulation following exposure of osteoarthritic human articular chondrocytes to hyperosmotic conditions. 3'UTR, HAC, IPA, MAPK, miRNA, TGF-beta
100  2011 Posttranscriptional control of type I interferon genes by KSRP in the innate immune response against viral infection. KSRP