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■ Abbreviation / Long Form : ATF3 / activating transcription factor 3

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Total Number of Papers: 525
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Abbreviation:   ATF3  (>> Co-occurring Abbreviation)
Long Form:   activating transcription factor 3
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No. Year Title Co-occurring Abbreviation
2020 Activating Transcription Factor 3 (ATF3) Protects Retinal Ganglion Cells and Promotes Functional Preservation After Optic Nerve Crush. ONC, PTEN, rAAVs, RBPMS, RGC
2020 Activating transcription factor 3 modulates the macrophage immune response to Mycobacterium tuberculosis infection via reciprocal regulation of inflammatory genes and lipid body formation. LBs, TFs
2020 Activation of ATF3/AP-1 signaling pathway is required for P2X3-induced endometriosis pain. ADP, AP, ATP, ChIP, CSOSA, DRG, LPs, P2X3
2020 ATF3 promotes erastin-induced ferroptosis by suppressing system Xc. ---
2020 CRLS1 ameliorates nonalcoholic steatohepatitis through ATF3 transcriptional inactivation. CRLS1, HFD, HFHC, NASH
2020 Epstein-Barr virus-positive gastric cancer involves enhancer activation through activating transcription factor 3. EBNA1, EBV, FAIRE, GC, TFs
2020 Hepatic IRF2BP2 Mitigates Nonalcoholic Fatty Liver Disease by Directly Repressing the Transcription of ATF3. IRF2BP2, NAFLD
2020 Potential Molecular Mechanism and Biomarker Investigation for Spinal Cord Injury Based on Bioinformatics Analysis. CRH, DEG, GEO, NTS, PPI, SCI, TH
2020 Secretome-Mediated Interactions with Intestinal Epithelial Cells: A Role for Secretome Components from Lactobacillus rhamnosus R0011 in the Attenuation of Salmonella enterica Serovar Typhimurium Secretome and TNF-alpha-Induced Proinflammatory Responses. DUSP1, MIF, STS, TRIB3
10  2020 Steroidogenic Factor 1 (NR5A1) Activates ATF3 Transcriptional Activity. SUMO
11  2020 Targeting SGK1 enhances the efficacy of radiotherapy in locally advanced rectal cancer. IHC, LARC, non-pCR, RT, SGK1
12  2020 The mRNA levels of heat shock factor 1 are regulated by thermogenic signals via the cAMP-dependent transcription factor ATF3. HSF1
13  2020 Up-Regulation of Activating Transcription Factor 3 in Human Fibroblasts Inhibits Melanoma Cell Growth and Migration Through a Paracrine Pathway. HDFs
14  2019 Activating transcription factor 3 modulates protein kinase C epsilon activation in diabetic peripheral neuropathy. Bcl-xL, DPN
15  2019 An ATF3-CreERT2 Knock-In Mouse for Axotomy-Induced Genetic Editing: Proof of Principle. PTEN
16  2019 Anti-inflammatory effects of naturally occurring retinoid X receptor agonists isolated from Sophora tonkinensis Gagnep. via retinoid X receptor/liver X receptor heterodimers. AD, IL, LXR, mRNA, NF-kappaB, RXR
17  2019 Assessment of potential neuropathic changes in cattle after cautery disbudding. GFAP, TH
18  2019 ATF3 and JDP2 deficiency in cancer associated fibroblasts promotes tumor growth via SDF-1 transcription. bZIP, JDP2, SDF-1, WT
19  2019 Circ_0001742 promotes tongue squamous cell carcinoma progression via miR-431-5p/ATF3 axis. ceRNA, circRNAs, EMT, MTT, qRT-PCR, RIP, TSCC
20  2019 Contribution of Inflammation and Bone Destruction to Pain in Arthritis: A Study in Murine Glucose-6-Phosphate Isomerase-Induced Arthritis. G6PI, ZA
21  2019 Electroacupuncture downregulates P2X3 receptor expression in dorsal root ganglia of the spinal nerve-ligated rat. P2X3Rs
22  2019 Histone deacetylase 6 negatively regulated microRNA-199a-5p induces the occurrence of preeclampsia by targeting VEGFA in vitro. DNM3os, HDAC6, miRNAs, PE, PlGF, VEGF-A
23  2019 Inhibitory effects of pirfenidone on fibroblast to myofibroblast transition in rheumatoid arthritis-associated interstitial lung disease via the downregulation of activating transcription factor 3 (ATF3). FMT, IPF, KD, PFD, phLFs, RA-ILD
24  2019 JDP2 and ATF3 deficiencies dampen maladaptive cardiac remodeling and preserve cardiac function. dKO, KO, TAC, WT
25  2019 LncRNA-MTA2TR functions as a promoter in pancreatic cancer via driving deacetylation-dependent accumulation of HIF-1alpha. lncRNA, MTA2, OS, PC
26  2019 Mitochondrial oxidative stress-induced transcript variants of ATF3 mediate lipotoxic brain microvascular injury. HBMECs, HTS, ROS, TGRL, TL, VaD
27  2019 Nicorandil prevents doxorubicin-induced human umbilical vein endothelial cell apoptosis. DOX, HO-1, HUVECs, Nrf2
28  2019 Overexpression of activating transcription factor 3 exerts suppressive effects in HepG2 cells. LV
29  2019 Prostaglandin E2 down-regulates sirtuin 1 (SIRT1), leading to elevated levels of aromatase, providing insights into the obesity-breast cancer connection. ASCs, EP2, HIF-1alpha, PGE2, SIRT1
30  2019 Sensory Neurons of the Dorsal Root Ganglia Become Hyperexcitable in a T-Cell-Mediated MOG-EAE Model of Multiple Sclerosis. DRG, EAE, MOG, MS
31  2019 Stimulation of ATF3 interaction with Smad4 via TGF-beta1 for matrix metalloproteinase 13 gene activation in human breast cancer cells. MMP13, TGF-beta1
32  2019 Sulfuretin Prevents Obesity and Metabolic Diseases in Diet Induced Obese Mice. ---
33  2019 The Association of Neuronal Stress with Activating Transcription Factor 3 in Dorsal Root Ganglion of in vivo and in vitro Models of Bortezomib- Induced Neuropathy. BTZ, DRG, ER, siRNA
34  2019 The mechanism of ATF3 repression of epithelial-mesenchymal transition and suppression of cell viability in cholangiocarcinoma via p53 signal pathway. CC, EMT, qRT-PCR
35  2019 The MRVI1-AS1/ATF3 signaling loop sensitizes nasopharyngeal cancer cells to paclitaxel by regulating the Hippo-TAZ pathway. lncRNA, NPC
36  2019 The role of ATF3 in ZnO nanoparticle-induced genotoxicity and cytotoxicity in bronchial epithelial cells. HBE, Nrf2, ZnO NP
37  2019 Transcriptional factor ATF3 protects against colitis by regulating follicular helper T cells in Peyer's patches. TFH
38  2019 [Expression of KCNA2 in the dorsal root ganglia of rats with osteoarthritis pain induced by monoiodoacetate]. DRG, iNOS, OA, PWMT
39  2018 Activating transcription factor 3 promotes intestinal epithelial cell apoptosis in Crohn's disease. CD, IBD, IEC, TNBS
40  2018 Activating transcription factor 3, an early cellular adaptive responder in ischemia/reperfusion-induced injury. I/R
41  2018 Activation of ERK/CREB pathway in noradrenergic neurons contributes to hypernociceptive phenotype in H4 receptor knockout mice after nerve injury. CREB, DbetaH, SNI
42  2018 Advances in Experimental Medicine and Biology: Intrafascicular Local Anesthetic Injection Damages Peripheral Nerve-Induced Neuropathic Pain. DRG, LA, PNB, SDH
43  2018 Atf3 deficiency promotes genome instability and spontaneous tumorigenesis in mice. DDR, MEFs
44  2018 Atf3 induction is a therapeutic target for obesity and metabolic diseases. CD, HFD, KO, WT
45  2018 ATF3 inhibits the tumorigenesis and progression of hepatocellular carcinoma cells via upregulation of CYR61 expression. ChIP, CYR61, HCC, TMAs
46  2018 Atf3 links loss of epithelial polarity to defects in cell differentiation and cytoarchitecture. JNK
47  2018 ATF3 mediates the inhibitory action of TNF-alpha on osteoblast differentiation through the JNK signaling pathway. JNK, TNF
48  2018 ATF3 Regulates the Expression of AChE During Stress. AChE, INL, ONL
49  2018 ATF3 represses PINK1 gene transcription in lung epithelial cells to control mitochondrial homeostasis. IPF, ISR, PINK1
50  2018 ATF3 Stimulates IL-17A by Regulating Intracellular Ca2+/ROS-Dependent IL-1beta Activation During Streptococcus pneumoniae Infection. ---
51  2018 ATF3 Sustains IL-22-Induced STAT3 Phosphorylation to Maintain Mucosal Immunity Through Inhibiting Phosphatases. AMP, IBD, PTPs
52  2018 Axonal Injury Induces ATF3 in Specific Populations of Sacral Preganglionic Neurons in Male Rats. HSP25
53  2018 Blockade of anoctamin-1 in injured and uninjured nerves reduces neuropathic pain. SNL, SNT
54  2018 Botanical Formulation HX109 Ameliorates TP-Induced Benign Prostate Hyperplasia in Rat Model and Inhibits Androgen Receptor Signaling by Upregulating Ca2+/CaMKKbeta and ATF3 in LNCaP Cells. AR, BPH, CaMKKbeta, HPLC, TP
55  2018 Camel whey protein protects lymphocytes from apoptosis via the PI3K-AKT, NF-kappaB, ATF-3, and HSP-70 signaling pathways in heat-stressed male mice. CWP, HS, IL, ROS
56  2018 Cardiac Fibroblast-Specific Activating Transcription Factor 3 Promotes Myocardial Repair after Myocardial Infarction. CFs, MI, qRT-PCR
57  2018 Carnosol suppresses interleukin-6 production in mouse lungs injured by ischemia-reperfusion operation and in RAW264.7 macrophages treated with lipopolysaccharide. IL-6
58  2018 Cytokine-induced cysteine- serine-rich nuclear protein-1 (CSRNP1) selectively contributes to MMP1 expression in human chondrocytes. AP-1, CSRNP1, MMPs
59  2018 Distinct TrkA and Ret modulated negative and positive neuropathic behaviors in a mouse model of resiniferatoxin-induced small fiber neuropathy. 4-MC, DRG, RTX
60  2018 Drug-Induced HSP90 Inhibition Alleviates Pain in Monoarthritic Rats and Alters the Expression of New Putative Pain Players at the DRG. 17-DMAG, DRG, GFAP, Hsp90, MA, SGC
61  2018 Early Gene Expression Profile in Retinal Ganglion Cell Layer After Optic Nerve Crush in Mice. Lcn2, ONC, RGC, Tnfrsf12a
62  2018 Effects of extracellular orotic acid on acute contraction-induced adaptation patterns in C2C12 cells. AMPK, Egr-1, EPS, mTOR, NR4A3, OA
63  2018 Evaluation of the neonatal streptozotocin model of diabetes in rats: Evidence for a model of neuropathic pain. DRG, SGC
64  2018 Genetic variants with gene regulatory effects are associated with diisocyanate-induced asthma. CDH17, DA, NGS, SNPs, TACR1, ZBTB16
65  2018 Inducible ATF3-NFAT axis aggravates podocyte injury. HG, LPS
66  2018 Loss of ATF3 exacerbates liver damage through the activation of mTOR/p70S6K/ HIF-1alpha signaling pathway in liver inflammatory injury. BMMs, HIF, HMGB1, IRI, KO, mTOR, PHD1
67  2018 MicroRNA-488 inhibits tongue squamous carcinoma cell invasion and EMT by directly targeting ATF3. EMT, miRNA, TSCC
68  2018 miR-342-3p promotes osteogenic differentiation via targeting ATF3. EVL, miRNAs
69  2018 NDRG1 Downregulates ATF3 and Inhibits Cisplatin-Induced Cytotoxicity in Lung Cancer A549 Cells. NDRG1
70  2018 Nerve Injury Increases the Expression of Alpha-2/Delta-1 Subunit of L-Type Calcium Channel in Sensory Neurons of Rat Spinal and Trigeminal Nerves. DRGs, TG
71  2018 Neuroinflammation after Traumatic Brain Injury Is Enhanced in Activating Transcription Factor 3 Mutant Mice. CNS, PNS, RAG, TBI, TFs
72  2018 Perlecan/HSPG2: Signaling role of domain IV in chondrocyte clustering with implications for Schwartz-Jampel Syndrome. ACAN, CDKN1C, COJ, HSPG2, mRNA, PCM
73  2018 Prolonged-duration pulsed radiofrequency is associated with increased neuronal damage without further antiallodynic effects in neuropathic pain model rats. DRG, HCN, PRF, SNL
74  2018 Protein kinase D3 modulates MMP1 and MMP13 expression in human chondrocytes. AP-1, ECM, IL-1, MMP1, OSM, PKC, PKD, STAT3
75  2018 Regulation of the ATF3 gene by a single promoter in response to amino acid availability and endoplasmic reticulum stress in human primary hepatocytes and hepatoma cells. ---
76  2018 RNA-Seq revealed ATF3-regulated inflammation induced by silica. DAVID, STRING
77  2018 Role of activating transcription factor 3 and its interacting proteins under physiological and pathological conditions. AP-1, PTM
78  2018 Role of activating transcription factor 3 in fructose-induced metabolic syndrome in mice. KO, SBP
79  2018 Serum and Adipose Tissue mRNA Levels of ATF3 and FNDC5/Irisin in Colorectal Cancer Patients With or Without Obesity. CRC, FNDC5, NW, OW/OB, ROC
80  2018 The Activating Transcription Factor 3 (Atf3) Homozygous Knockout Mice Exhibit Enhanced Conditioned Fear and Down Regulation of Hippocampal GELSOLIN. ---
81  2018 TLR-induced secretion of novel cytokine IL-27 is defective in newly diagnosed type-2 diabetic subjects. HLA-DR, NGT, TLRs
82  2018 Transcription factor ATF3 mediates the radioresistance of breast cancer. ---
83  2017 Acidosis Activates Endoplasmic Reticulum Stress Pathways through GPR4 in Human Vascular Endothelial Cells. ECs, ER, GPR4, HUVEC, UPR, XBP1
84  2017 Activating transcription factor 3 (ATF3) protects against lipopolysaccharide-induced acute lung injury via inhibiting the expression of TL1A. ALI, KO, LPS, WT
85  2017 Activating transcription factor 3 in immune response and metabolic regulation. CREB
86  2017 Activating transcription factor 3 is a target molecule linking hepatic steatosis to impaired glucose homeostasis. NAFLD, T2D, ZDF
87  2017 Activating transcription factor 3 is crucial for antitumor activity and to strengthen the antiviral properties of Onconase. ---
88  2017 Activating Transcription Factor 3 Is Essential for Cigarette Smoke-Induced Mucin Expression via Interaction with Activator Protein-1. CS, MUC5AC
89  2017 Activating Transcription Factor 3 Is Reduced in Preeclamptic Placentas and Negatively Regulates sFlt-1 (Soluble fms-Like Tyrosine Kinase 1), Soluble Endoglin, and Proinflammatory Cytokines in Placenta. ---
90  2017 Activating transcription factor 3 promotes embryo attachment via up-regulation of leukemia inhibitory factor in vitro. FER, IF, IHC, LIF, MPA, qRT-PCR, RIF
91  2017 Activating transcription factor 3 promotes loss of the acinar cell phenotype in response to cerulein-induced pancreatitis in mice. PDAC
92  2017 Activating transcription factor 3 promotes malignance of lung cancer cells in vitro. ---
93  2017 Activating transcription factor 3 promotes spinal cord regeneration of adult zebrafish. CNS, IL-1beta, MO, qPCR, SCI, TNF-alpha
94  2017 Activating transcription factor 3 protects mice against pseudomonas aeruginosa-induced acute lung injury by interacting with lipopolysaccharide binding protein. ALI, Co-ip, KO, WT
95  2017 Activating transcription factor 3 represses cigarette smoke-induced IL6 and IL8 expression via suppressing NF-kappaB activation. BALF, COPD, CS, CSE, HBE, IL-6, IL-8, NF-kappaB
96  2017 ATF3 inhibits the inflammation induced by Mycoplasma pneumonia in vitro and in vivo. Egr-1, MP
97  2017 ATF3 modulates calcium signaling in osteoclast differentiation and activity by associating with c-Fos and NFATc1 proteins. BMMs, NFATc1, TRAP
98  2017 ATF3 promotes migration and M1/M2 polarization of macrophages by activating tenascin‑C via Wnt/beta‑catenin pathway. CD, TN-C, Wnt
99  2017 ATF3 reduces migration capacity by regulation of matrix metalloproteinases via NFkappaB and STAT3 inhibition in glioblastoma. ---
100  2017 ATF3-Dependent Regulation of EGR1 in vitro and in vivo. Egr-1, MOCs