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■ Abbreviation / Long Form : BCRP / breast cancer resistance protein

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Total Number of Papers: 1089
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Abbreviation:   BCRP  (>> Co-occurring Abbreviation)
Long Form:   breast cancer resistance protein
 Abbreviation Variation
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No. Year Title Co-occurring Abbreviation
2020 A Combination of Clioquinol, Zinc and Copper Increases the Abundance and Function of Breast Cancer Resistance Protein in Human Brain Microvascular Endothelial Cells. BBB, BP, CQ, P-gp
2020 Abundant Expression of OCT2, MATE1, OAT1, OAT3, PEPT2, BCRP, MDR1, and xCT Transporters in Blood-Arachnoid Barrier of Pig and Polarized Localizations at CSF- and Blood-Facing Plasma Membranes. BAB, BCSFB, CSF, GLUT1, MATE1, MCT, MDR1, MRP, OAT, OATP, OCT, PEPT
2020 Assessment of contribution of BCRP to intestinal absorption of various drugs using portal-systemic blood concentration difference model in mice. AQ, NCEs, P-gp, P-S, WT
2020 Assessment of Transporter Polymorphisms as a Factor in a BCRP Drug Interaction Study With Lanabecestat. AUC, PK, Tmax
2020 Assessment of transporter-mediated efflux of nintedanib using in vitro cell line models of idiopathic pulmonary fibrosis. MDR1, MRP1, TGF-beta1
2020 beta-Sitosterol Reverses Multidrug Resistance via BCRP Suppression by Inhibiting the p53-MDM2 Interaction in Colorectal Cancer. CRC, NF-kappaB, OXA
2020 Bile duct ligation enhances AZT CNS toxicity partly by impairing the expression and function of BCRP in rat brain. ABC, AUC, BDL, SO
2020 Bleomycin Induces Drug Efflux in Lungs. A Pitfall for Pharmacological Studies of Pulmonary Fibrosis. ABC, BLM, IPF
2020 Cannabidiol Effects on Phospholipid Metabolism in Keratinocytes from Patients with Psoriasis Vulgaris. CBD, MDR, PEA, ROS
10  2020 Description of Druglike Properties of Safranal and Its Chemistry behind Low Oral Exposure. P-gp
11  2020 Dysfunction of ABC transporters at the blood-brain barrier: Role in neurological disorders. ABC, BBB, CNS, MPRs, P-gp
12  2020 Effect of GenX on P-Glycoprotein, Breast Cancer Resistance Protein, and Multidrug Resistance-Associated Protein 2 at the Blood-Brain Barrier. BBB, MRP2, P-gp, PPARgamma
13  2020 Effects of Multiple-Dose Administration of Aprocitentan on the Pharmacokinetics of Rosuvastatin. ---
14  2020 Elevated system exposures of baicalin after combinatory oral administration of rhein and baicalin: Mainly related to breast cancer resistance protein (ABCG2), not UDP-glucuronosyltransferases. TCM, UGTs
15  2020 Estimating Efflux Transporter-Mediated Disposition of Molecules beyond the Rule of Five (bRo5) Using Transporter Gene Knockout Rats. P-gp
16  2020 Expression and Cellular Distribution of P-Glycoprotein and Breast Cancer Resistance Protein in Amyotrophic Lateral Sclerosis Patients. ABC, ALS, P-gp, SC
17  2020 Extrahepatic metabolism of ibrutinib. MRP, P-gp
18  2020 Gestational Age-Dependent Abundance of Human Placental Transporters as Determined by Quantitative Targeted Proteomics. OATP, OCT, P-gp
19  2020 Identification of Functional Transcriptional Binding Sites within Chicken Abcg2 Gene Promoter and Screening Its Regulators. ABC, LMH, LPS
20  2020 Identification of structural fingerprints for ABCG2 inhibition by using Monte Carlo optimization, Bayesian classification, and structural and physicochemical interpretation (SPCI) analysis. ABC, SPCI
21  2020 Imbalance of Drug Transporter-CYP450s Interplay by Diabetes and Its Clinical Significance. CYP450s, MCTs, MRPs, OATPs, OATs, OCTs, P-gp, PepTs, UGTs
22  2020 In vitro assessment of P-gp and BCRP transporter-mediated drug-drug interactions of riociguat with direct oral anticoagulants. CTEPH, DOACs, P-gp, VKAs
23  2020 In-Depth Characterization of EpiIntestinal Microtissue as a Model for Intestinal Drug Absorption and Metabolism in Human. CES, CYP3A4, P-gp, UGT
24  2020 Induction of Human Intestinal and Hepatic Organic Anion Transporting Polypeptides: Where Is the Evidence for Its Relevance in Drug-Drug Interactions? CBZ, CPI, CYP3A4, MRP2, OATPs, P-gp, PK, RIF
25  2020 Investigation of MDR1-overexpressing cell lines to derive a quantitative prediction approach for brain disposition using in vitro efflux activities. CFR, ER, WT
26  2020 Malaria in pregnancy regulates P-glycoprotein (P-gp/Abcb1a) and ABCA1 efflux transporters in the Mouse Visceral Yolk Sac. GD, IL, IUGR, MiP, PTL
27  2020 Metabolism and disposition of corylifol A from Psoralea corylifolia: metabolite mapping, isozyme contribution, species differences and identification of efflux transporters for corylifol A-O-glucuronide in HeLa1A1 cells. CA, MRPs, UGTs
28  2020 Overcoming Multidrug Resistance: Flavonoid and Terpenoid Nitrogen-Containing Derivatives as ABC Transporter Modulators. ABC, MDR, MRP1, P-gp
29  2020 Pharmacokinetic Drug-Drug Interaction of Apalutamide, Part 1: Clinical Studies in Healthy Men and Patients with Castration-Resistant Prostate Cancer. OATP, P-gp
30  2020 Placental transporter-mediated drug interactions and offspring congenital anomalies. P-gp
31  2020 Poncirin downregulates ATP-binding cassette transporters to enhance cisplatin sensitivity in cisplatin-resistant osteosarcoma cells. MDR1, OS, PI3K
32  2020 Quantitative Prediction of Interactions Mediated by Transporters and Cytochromes: Application to Organic Anion Transporting Polypeptides, Breast Cancer Resistance Protein and Cytochrome 2C8. AUC, CRs, DDIs, IMSM, OATP
33  2020 Quercetin Is a Flavonoid Breast Cancer Resistance Protein Inhibitor with an Impact on the Oral Pharmacokinetics of Sulfasalazine in Rats. HeLa cells
34  2020 Regulation of breast cancer resistance protein and P-glycoprotein by ezrin, radixin and moesin in lung, intestinal and renal cancer cell lines. Ezr, MSN, RDX, Rho123
35  2020 Role of Elevated SFLT-1 on the Regulation of Placental Transporters in Women With Pre-Eclampsia. PE
36  2020 Short-chain fatty acids exert opposite effects on the expression and function of p-glycoprotein and breast cancer resistance protein in rat intestine. P-gp, p-p65, SCFAs
37  2020 Study of the Characterization of Side Population Cells in Endometrial Cancer Cell Lines: Chemoresistance, Progestin Resistance, and Radioresistance. EC, SP
38  2020 Talazoparib nanoparticles for overcoming multidrug resistance in triple-negative breast cancer. SLNs, TNBC
39  2020 The dual orexin receptor antagonist daridorexant does not affect the pharmacokinetics of the BCRP substrate rosuvastatin. DDI, GMRs, OD, PK
40  2020 The impact of breast cancer resistant protein (BCRP/ABCG2) on drug transport across Caco-2 cell monolayers. AQ, ER, P AB, P-gp
41  2020 The influence of the coadministration of the p-glycoprotein modulator elacridar on the pharmacokinetics of lapatinib and its distribution in the brain and cerebrospinal fluid. ABC, BC, BP, BT, CSF, HER2
42  2020 The p53-53BP1-Related Survival of A549 and H1299 Human Lung Cancer Cells after Multifractionated Radiotherapy Demonstrated Different Response to Additional Acute X-ray Exposure. DSB, IR, MFR, NHEJ, NSCLC, pATM
43  2020 The Pyrazolo[3,4-d]pyrimidine Derivative, SCO-201, Reverses Multidrug Resistance Mediated by ABCG2/BCRP. ABC
44  2020 Transport mechanism and affinity of [99mTc]mercaptoacetyltriglycine ([99mTc]MAG3) on the apical membrane of renal proximal tubule cells. ABC, EHBR, MDR1, MRP, OAT, SPECT
45  2020 Usefulness of novobiocin as a selective inhibitor of intestinal breast cancer resistance protein (Bcrp) in rats. OATP, P-gp
46  2019 ABC Transporters in Extrahepatic Tissues: Pharmacological Regulation in Heart and Intestine. ABC, MRP1 and 2, P-gp
47  2019 Aryl hydrocarbon receptor ligands increase ABC transporter activity and protein expression in killifish (Fundulus heteroclitus) renal proximal tubules. AhR, BNF, P-gp, TCDD
48  2019 Astragali radix and its main bioactive compounds activate the Nrf2-mediated signaling pathway to induce P-glycoprotein and breast cancer resistance protein. ARE, AS-IV, CS, FMNT, HDIs, P-gp
49  2019 ATP-binding Cassette Transporters Substantially Reduce Estimates of ALDH-positive Cancer Cells based on Aldefluor and AldeRed588 Assays. ABC, ALDH, MDR1, MRP
50  2019 Brain Distribution and Active Efflux of Three panRAF Inhibitors: Considerations in the Treatment of Melanoma Brain Metastases. BBB, MAPK, P-gp
51  2019 Brain region-specific regulation of histone acetylation and efflux transporters in mice. HDAC, MDR1, VPA
52  2019 Breast Cancer Resistance Protein (BCRP/ABCG2) Inhibits Extra Villous Trophoblast Migration: The Impact of Bacterial and Viral Infection. EVT, IUGR, LPS, PE, ssRNA
53  2019 Breast Cancer Resistance Protein and Multidrug Resistance Protein 2 Determine the Disposition of Esculetin-7-O-Glucuronide and 4-Methylesculetin-7-O-Glucuronide. 4-Me, 4-ME-G, ET, MRP2
54  2019 Breast cancer resistance protein is the enemy of hypericin accumulation and toxicity of hypericin-mediated photodynamic therapy. ABC, HY, MRP1, P-gp, PDD, PDT
55  2019 Chemo-sensitizing activity of natural cadinanes from Heterotheca inuloides in human uterine sarcoma cells and their in silico interaction with ABC transporters. MRP1
56  2019 Cloning, expression of the truncation of recombinant peroxidase derived from millet bran and its reversal effects on 5-Fu resistance in colorectal cancer. MRP1, P-gp, pMal-s
57  2019 Comparative pharmacokinetics of tedizolid in rat plasma and cerebrospinal fluid. P-gp
58  2019 Comparison of LC-MS/MS-based targeted proteomics and conventional analytical methods for monitoring breast cancer resistance protein expression. ABC, RT-PCR, WB
59  2019 Concomitant febuxostat enhances methotrexate-induced hepatotoxicity by inhibiting breast cancer resistance protein. FAERS, FBX, HDMTX, MTX
60  2019 Contributions of Drug Transporters to Blood-Placental Barrier. MATE1, OAT4, OCT3, P-gp
61  2019 Cytosolic phospholipase A2 is a key regulator of blood-brain barrier function in epilepsy. CE, cPLA2, P-gp, SE
62  2019 Cytotoxicity of cucurbitacin E from Citrullus colocynthis against multidrug-resistant cancer cells. CuE, EGFR, P-gp
63  2019 Development of a Ternary Solid Dispersion Formulation of LW6 to Improve the In Vivo Activity as a BCRP Inhibitor: Preparation and In Vitro/In Vivo Characterization. DSC, FTIR, SD, SEM, XRPD
64  2019 Development of Human in vitro Brain-blood Barrier Model from Induced Pluripotent Stem Cell-derived Endothelial Cells to Predict the in vivo Permeability of Drugs. BBB, hiPSC, iPSC, P-gp, TEER
65  2019 Development of precision medicine approaches based on inter-individual variability of BCRP/ABCG2. ---
66  2019 Downregulation of cytokeratin 18 enhances BCRP-mediated multidrug resistance through induction of epithelial-mesenchymal transition and predicts poor prognosis in breast cancer. CK18, EMT, MDR
67  2019 Downregulation of organic cation transporter 1 and breast cancer resistance protein with the induction of Pregnane X receptor in rat kidney impaired by doxorubicin. DOX, OCT1, PXR
68  2019 Drug-Drug Interaction Potential of Darolutamide: In Vitro and Clinical Studies. AR, DDI, nmCRPC, OAT, OATP, P-gp
69  2019 Effect of Macitentan on the Pharmacokinetics of the Breast Cancer Resistance Protein Substrates, Rosuvastatin and Riociguat, in Healthy Male Subjects. AUC, Cmax, DDIs, PAH
70  2019 Effect of Stereochemical Configuration on the Transport and Metabolism of Catechins from Green Tea across Caco-2 Monolayers. CG, EC, ECG, EGC, EGCG, GCG, GTCs, MRP2
71  2019 Effects of P-gp and Bcrp as brain efflux transporters on the uptake of [18 F]FPEB in the murine brain. P-gp
72  2019 Evaluation of inhibitory effects of flavonoids on breast cancer resistance protein (BCRP): From library screening to biological evaluation to structure-activity relationship. ---
73  2019 Ex vivo resistance in childhood acute lymphoblastic leukemia: Correlations between BCRP, MRP1, MRP4 and MRP5 ABC transporter expression and intracellular methotrexate polyglutamate accumulation. ALL, MRP1-5, MTX, TSIA
74  2019 F127 poloxamer effect on cytotoxicity induction of tumour cell cultures treated with doxorubicin. ---
75  2019 Genome-Wide Association and Functional Studies Reveal Novel Pharmacological Mechanisms for Allopurinol. UA
76  2019 Guajadial reverses multidrug resistance by inhibiting ABC transporter expression and suppressing the PI3K/Akt pathway in drug-resistant breast cancer cells. ABC, ADR, P-gp, PTX
77  2019 Identification and Characterization of Efflux Transporters That Modulate the Subtoxic Disposition of Diclofenac and Its Metabolites. DCF, DCF-AG, KO, MRP, WT
78  2019 Identification of UGTs and BCRP as potential pharmacokinetic determinants of the natural flavonoid alpinetin. HeLa1A1, pHIM, pHLM, UGTs
79  2019 Imaging of hepatic drug transporters with [131I]6-beta-iodomethyl-19-norcholesterol. ABC, MRP, OATP, SPECT
80  2019 Impact of Zn2+ on ABC Transporter Function in Intact Isolated Rat Brain Microvessels, Human Brain Capillary Endothelial Cells, and in Rat in Vivo. BBB, ETB, MRP2, mTOR, NOS, P-gp, PI3K, PKC, SGK1, Zn
81  2019 Improved In vivo Effect of Chrysin as an Absorption Enhancer Via the Preparation of Ternary Solid Dispersion with BrijL4 and Aminoclay. SDs
82  2019 In Vitro Evaluation of the Drug Interaction Potential of Doravirine. BSEP, CYP3A, DDIs, MATE1, OAT1, OATP1B1, OCT2
83  2019 In Vitro Mechanistic Study of the Distribution of Lascufloxacin into Epithelial Lining Fluid. ELF, P-gp, PhS
84  2019 In-vitro and insitu assessment of the efflux of five antidepressants by breast cancer resistance protein. BBB, NER, WT
85  2019 Influence of OATP1B1 and BCRP polymorphisms on the pharmacokinetics and pharmacodynamics of rosuvastatin in elderly and young Korean subjects. AUC, IF, PDs, PKs
86  2019 Inhibition of MALAT1 reduces tumor growth and metastasis and promotes drug sensitivity in colorectal cancer. ABC, CRC, MALAT1
87  2019 Intestinal Absorption of Isoalantolactone and Alantolactone, Two Sesquiterpene Lactones from Radix Inulae, Using Caco-2 Cells. MRPs
88  2019 Intestinal breast cancer resistance protein (BCRP) requires Janus kinase 3 activity for drug efflux and barrier functions in obesity. ABC, CLGI, JAK3
89  2019 Lysosomal P-gp-MDR1 Confers Drug Resistance of Brentuximab Vedotin and Its Cytotoxic Payload Monomethyl Auristatin E in Tumor Cells. ABC, ADCs, MMAE, MRP
90  2019 Mechanism of the efflux transport of demethoxycurcumin-O-glucuronides in HeLa cells stably transfected with UDP-glucuronosyltransferase 1A1. DMC, MRPs, UGT1A1
91  2019 Metabolism, Transport and Drug-Drug Interactions of Silymarin. ---
92  2019 Metabolome Analysis Reveals Dermal Histamine Accumulation in Murine Dermatitis Provoked by Genetic Deletion of P-Glycoprotein and Breast Cancer Resistance Protein. P-gp
93  2019 MicroRNA‑302a upregulation mediates chemo‑resistance in prostate cancer cells. miRNAs
94  2019 Modulation of hepatic ABC transporters by Eruca vesicaria intake: Potential diet-drug interactions. CP, MRP2
95  2019 Modulation of the spacer in N,N-bis(alkanol)amine aryl ester heterodimers led to the discovery of a series of highly potent P-glycoprotein-based multidrug resistance (MDR) modulators. MDR, MRP1, PBS
96  2019 Molecular transport through primary human small intestinal monolayers by culture on a collagen scaffold with a gradient of chemical cross-linking. ECM, MRP2
97  2019 Multiple Drug Transporters Contribute to the Placental Transfer of Emtricitabine. CNTs, ENTs, MDR1, MRPs, OCTN1, OCTs, PHTCs, siRNAs
98  2019 Muscle to Brain Partitioning as Measure of Transporter-Mediated Efflux at the Rat Blood-Brain Barrier and Its Implementation into Compound Optimization in Drug Discovery. BBB, CNS
99  2019 Nilotinib Alters the Efflux Transporter-Mediated Pharmacokinetics of Afatinib in Mice. P-gp, TKIs
100  2019 Novel 3,4-Dihydroisocoumarins Inhibit Human P-gp and BCRP in Multidrug Resistant Tumors and Demonstrate Substrate Inhibition of Yeast Pdr5. ABC, MDR, MRP1, P-gp