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■ Abbreviation / Long Form : BH / Bcl-2 homology

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Total Number of Papers: 87
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Abbreviation:   BH  (>> Co-occurring Abbreviation)
Long Form:   Bcl-2 homology
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No. Year Title Co-occurring Abbreviation
2019 BCL-2 family isoforms in apoptosis and cancer. ---
2019 BCL-2 family proteins in apoptosis and its regulation. Bcl-2
2019 Heterogeneous Pattern of Dependence on Anti-Apoptotic BCL-2 Family Proteins upon CHOP Treatment in Diffuse Large B-Cell Lymphoma. Bcl-2, DLBCL
2019 The small molecule Bcl-2/Mcl-1 inhibitor TW-37 shows single-agent cytotoxicity in neuroblastoma cell lines. ---
2018 B cell lymphoma 2 (Bcl-2) residues essential for Bcl-2's apoptosis-inducing interaction with Nur77/Nor-1 orphan steroid receptors. Bcl-2
2018 BH4 domain peptides derived from Bcl-2/Bcl-XL as novel tools against acute pancreatitis. AP, Bcl, PACs, RyR, TLC-S
2018 Contribution of BH3-domain and Transmembrane-domain to the Activity and Interaction of the Pore-forming Bcl-2 Proteins Bok, Bak, and Bax. ---
2017 APG-1252-12A induces mitochondria-dependent apoptosis through inhibiting the antiapoptotic proteins Bcl-2/Bcl-xl in HL-60 cells. AML, Bcl-2
2017 Apoptotic properties of the type 1 interferon induced family of human mitochondrial membrane ISG12 proteins. ISGs
10  2017 Extra-mitochondrial prosurvival BCL-2 proteins regulate gene transcription by inhibiting the SUFUtumour suppressor. OMM, Sufu
11  2017 The BH4 domain of Bcl-2 orthologues from different classes of vertebrates can act as an evolutionary conserved inhibitor of IP3 receptor channels. Bcl-2, ER, IICR
12  2016 Affinity purification-mass spectrometry analysis of bcl-2 interactome identified SLIRP as a novel interacting protein. mRNA
13  2016 BH4 domain of Bcl-2 as a novel target for cancer therapy. Bcl-2
14  2016 Targeting BCL-2-like Proteins to Kill Cancer Cells. Bcl, Mcl
15  2015 Bcl-2 and FKBP12 bind to IP3 and ryanodine receptors at overlapping sites: the complexity of protein-protein interactions for channel regulation. Bcl-2, RyRs
16  2015 HA14-1 potentiates apoptosis in B-cell cancer cells sensitive to a peptide disrupting IP 3 receptor / Bcl-2 complexes. B-CLL, Bcl-2, DLBCL, ER
17  2015 Identification and functional characterization of two Bcl-2 family protein genes in Zhikong scallop Chlamys farreri. aa, nt
18  2015 Mapping the BH3 Binding Interface of Bcl-xL, Bcl-2, and Mcl-1 Using Split-Luciferase Reassembly. ---
19  2015 MCL-1 and BCL-xL-dependent resistance to the BCL-2 inhibitor ABT-199 can be overcome by preventing PI3K/AKT/mTOR activation in lymphoid malignancies. ABT199-R, CLL, NHL
20  2015 Regulation of the ryanodine receptor by anti-apoptotic Bcl-2 is independent of its BH3-domain-binding properties. Bcl-2, ER, RyRs
21  2015 Ryanodine receptors are targeted by anti-apoptotic Bcl-XL involving its BH4 domain and Lys87 from its BH3 domain. Bcl-2, MAPPIT, RyRs, SPR
22  2015 The Bcl-2 family: structures, interactions and targets for drug discovery. Bcl-2, MOMP
23  2014 A dual role for the anti-apoptotic Bcl-2 protein in cancer: mitochondria versus endoplasmic reticulum. CLL, DLBCL, ER
24  2014 High-quality NMR structure of human anti-apoptotic protein domain Mcl-1(171-327) for cancer drug design. hMcl-1
25  2014 Regulation of hepatic energy metabolism and gluconeogenesis by BAD. BAD
26  2014 The use of a neutral peptide aptamer scaffold to anchor BH3 peptides constitutes a viable approach to studying their function. Bad, Bak, Bax, Bcl-2, Bim
27  2013 Evolution of Bcl-2 homology motifs: homology versus homoplasy. ---
28  2013 Minor cell-death defects but reduced tumor latency in mice lacking the BH3-only proteins Bad and Bmf. ---
29  2013 Polyubiquitination and proteasomal turnover controls the anti-apoptotic activity of Bcl-B. ---
30  2013 Prophylactic treatment with the BH3 mimetic ABT-737 impedes Myc-driven lymphomagenesis in mice. ---
31  2013 The selective BH4-domain biology of Bcl-2-family members: IP3Rs and beyond. ER
32  2013 Two molluscan BCL-2 family members from Manila clam, Ruditapes philippinarum: molecular characterization and immune responses. ---
33  2012 Bcl-2 family member Bcl-G is not a proapoptotic protein. ---
34  2012 Bcl-rambo induces apoptosis via interaction with the adenine nucleotide translocator. ANT
35  2012 Design of novel BH3 mimetics for the treatment of chronic lymphocytic leukemia. CLL
36  2012 Disruption of the VDAC2-Bak interaction by Bcl-x(S) mediates efficient induction of apoptosis in melanoma cells. Bcl, VDAC2
37  2012 Mcl-1 Phosphorylation defines ABT-737 resistance that can be overcome by increased NOXA expression in leukemic B cells. ---
38  2012 Molecular dynamics simulations of the Bcl-2 protein to predict the structure of its unordered flexible loop domain. ED, FLD, MD, PMDB, TM
39  2012 The restricted binding repertoire of Bcl-B leaves Bim as the universal BH3-only prosurvival Bcl-2 protein antagonist. Bcl-2
40  2011 Evidence that inhibition of BAX activation by BCL-2 involves its tight and preferential interaction with the BH3 domain of BAX. ---
41  2011 In vivo contributions of BH3-only proteins to neuronal death following seizures, ischemia, and traumatic brain injury. ---
42  2011 The Differential Effect of Toxoplasma Gondii Infection on the Stability of BCL2-Family Members Involves Multiple Activities. ---
43  2010 Cardiolipin, phosphatidylserine, and BH4 domain of Bcl-2 family regulate Ca2+/H+ antiporter activity of human Bax inhibitor-1. BI-1, CL, PC, PS
44  2010 Characterization and expression analyses of anti-apoptotic Bcl-2-like genes NR-13, Mcl-1, Bcl-X1, and Bcl-X2 in Atlantic cod (Gadus morhua). ASAL, ESTs, i.p, MMP, pIC, QPCR, TM
45  2010 Vaccinia virus F1L interacts with Bak using highly divergent Bcl-2 homology domains and replaces the function of Mcl-1. ---
46  2009 Small-molecule BH3 mimetics to antagonize Bcl-2-homolog survival functions in cancer. ---
47  2008 BH3-only proteins and their roles in programmed cell death. ---
48  2008 Differentially expressed pro- and anti-apoptogenic genes in response to benzene exposure: Immunohistochemical localization of p53, Bag, Bad, Bax, Bcl-2, and Bcl-w in lung epithelia. ---
49  2008 Iridovirus Bcl-2 protein inhibits apoptosis in the early stage of viral infection. Bcl, GIV, GK
50  2008 Synthesis and biophysical characterization of stabilized alpha-helices of BCL-2 domains. ---
51  2007 Apoptosis-based dual molecular targeting by INNO-406, a second-generation Bcr-Abl inhibitor, and ABT-737, an inhibitor of antiapoptotic Bcl-2 proteins, against Bcr-Abl-positive leukemia. ---
52  2007 Bcl-2 overexpression in thyroid carcinoma cells increases sensitivity to Bcl-2 homology 3 domain inhibition. ---
53  2007 Vaccinia virus N1L protein resembles a B cell lymphoma-2 (Bcl-2) family protein. Bcl-2
54  2006 A membrane-targeted BID BCL-2 homology 3 peptide is sufficient for high potency activation of BAX in vitro. tBid
55  2006 Auto-activation of the apoptosis protein Bax increases mitochondrial membrane permeability and is inhibited by Bcl-2. ---
56  2006 Mcl-1 interacts with truncated Bid and inhibits its induction of cytochrome c release and its role in receptor-mediated apoptosis. tBid
57  2005 An anti-apoptosis gene of the Bcl-2 family from Marine Birnavirus inhibiting apoptosis of insect cells infected with baculovirus. EGFP, MABV
58  2005 Apolipoprotein l6, a novel proapoptotic Bcl-2 homology 3-only protein, induces mitochondria-mediated apoptosis in cancer cells. ApoL6
59  2005 C-terminal region of Bfl-1 induces cell death that accompanies caspase activation when fused with GFP. GFP
60  2005 Combined loss of proapoptotic genes Bak or Bax with Bim synergizes to cause defects in hematopoiesis and in thymocyte apoptosis. ---
61  2005 Constitutive proteasome-mediated turnover of Bfl-1/A1 and its processing in response to TNF receptor activation in FL5.12 pro-B cells convert it into a prodeath factor. CHX, TNF
62  2005 Solution structure of prosurvival Mcl-1 and characterization of its binding by proapoptotic BH3-only ligands. Bcl-2, Mcl-1
63  2004 Proteins of the bcl-2 family in apoptosis signalling: from mechanistic insights to therapeutic opportunities. ---
64  2003 Bcl-2 proteins: targets and tools for chemosensitisation of tumor cells. ---
65  2003 Bfl-1S, a novel alternative splice variant of Bfl-1, localizes in the nucleus via its C-terminus and prevents cell death. STS
66  2003 Comparative analysis of apoptosis and inflammation genes of mice and humans. CARD, DD, DED, IAPs, TNF, TNFR
67  2003 Deletion of the BH1 domain of Bcl-2 accelerates apoptosis by acting in a dominant negative fashion. ---
68  2003 Targeting BCL-2-related proteins in cancer therapy. ---
69  2002 Bcl-XL protects BimEL-induced Bax conformational change and cytochrome C release independent of interacting with Bax or BimEL. DeltaC
70  2002 Direct addition of BimL to mitochondria does not lead to cytochrome c release. ---
71  2002 IPNV VP5, a novel anti-apoptosis gene of the Bcl-2 family, regulates Mcl-1 and viral protein expression. ---
72  2002 Phosphatidylinositol 3-kinase p85 adaptor function in T-cells. Co-stimulation and regulation of cytokine transcription independent of associated p110. Deltap85, PI3K
73  2002 The carboxy terminal C-tail of BNip3 is crucial in induction of mitochondrial permeability transition in isolated mitochondria. CsA, MPT, PTP, rBNip3, TM
74  2001 Bcl-B, a novel Bcl-2 family member that differentially binds and regulates Bax and Bak. TM
75  2001 Bcl-G, a novel pro-apoptotic member of the Bcl-2 family. ---
76  2001 Bcl-rambo, a novel Bcl-2 homologue that induces apoptosis via its unique C-terminal extension. ---
77  2001 Neuron-specific Bcl-2 homology 3 domain-only splice variant of Bak is anti-apoptotic in neurons, but pro-apoptotic in non-neuronal cells. NGF
78  2000 MCL-1S, a splicing variant of the antiapoptotic BCL-2 family member MCL-1, encodes a proapoptotic protein possessing only the BH3 domain. Mcl-1, MCL-1L, MCL-1S
79  2000 Simian virus 40 large T antigen binds a novel Bcl-2 homology domain 3-containing proapoptosis protein in the cytoplasm. Tag
80  2000 Tissue-specific Bcl-2 protein partners in apoptosis: An ovarian paradigm. Apaf
81  1999 The SH3 and BH domains of the p85alpha adapter subunit play a critical role in regulating class Ia phosphoinositide 3-kinase function. ---
82  1998 A splicing variant of the Bcl-2 member Bok with a truncated BH3 domain induces apoptosis but does not dimerize with antiapoptotic Bcl-2 proteins in vitro. ---
83  1998 Bcl-2-family proteins: the role of the BH3 domain in apoptosis. ---
84  1997 Bok is a pro-apoptotic Bcl-2 protein with restricted expression in reproductive tissues and heterodimerizes with selective anti-apoptotic Bcl-2 family members. Bok
85  1997 Expression and function of a proapoptotic Bcl-2 family member Bcl-XL/Bcl-2-associated death promoter (BAD) in rat ovary. Bad, mRNA
86  1996 Adenovirus E1B 19-kDa death suppressor protein interacts with Bax but not with Bad. ---
87  1996 bfl-1, a bcl-2 homologue, suppresses p53-induced apoptosis and exhibits potent cooperative transforming activity. ---