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■ Abbreviation / Long Form : BrM / Bruch's membrane

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Total Number of Papers: 67
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Abbreviation:   BrM  (>> Co-occurring Abbreviation)
Long Form:   Bruch's membrane
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No. Year Title Co-occurring Abbreviation
2021 AMD-Like Substrate Causes Epithelial Mesenchymal Transition in iPSC-Derived Retinal Pigment Epithelial Cells Wild Type but Not C3-Knockout. AMD, ECM, EMT, iPSC, RPE
2021 Hyperspectral autofluorescence characterization of drusen and sub-RPE deposits in age-related macular degeneration. AF, BLinD, LF, MLF, NMF
2021 Peptide-based immunotherapy against oxidized elastin ameliorates pathology in mouse model of smoke-induced ocular injury. AMD, PIT, SIOP
2021 Towards an In Vitro Retinal Model to Study and Develop New Therapies for Age-Related Macular Degeneration. AMD, BMSF, PCL, RPE
2020 Altered photoreceptor metabolism in mouse causes late stage age-related macular degeneration-like pathologies. AMD, DHA, GA, mTORC1, POS, PRs, RPE
2020 High-density lipoproteins are a potential therapeutic target for age-related macular degeneration. AMD, ApoA1, HDL, RPE
2020 Immunization Against Oxidized Elastin Exacerbates Structural and Functional Damage in Mouse Model of Smoke-Induced Ocular Injury. AMD, EL, RPE, SIOP
2020 Measurement of Diurnal Variation in Rod Outer Segment Length In Vivo in Mice With the OCT Optoretinogram. OCT, RIS, ROS, ROST
2019 A lasered mouse model of retinal degeneration displays progressive outer retinal pathology providing insights into early geographic atrophy. GA, RPE
10  2019 Abdominal obesity linked to a longer cone-mediated dark-adaptation recovery time in healthy eyes. BMI, CoR, cpd, CT, DA, WC, WHtR
11  2019 Loss-of-Function Mutations in the CFH Gene Affecting Alternatively Encoded Factor H-like 1 Protein Cause Dominant Early-Onset Macular Drusen. AMD, CFH, EOMD, FH, FHL1, MAF
12  2019 Role of the Choroid in Age-related Macular Degeneration: A Current Review. AMD, RPE
13  2019 Selective Retina Therapy Reduces Bruch's Membrane Thickness and Retinal Pigment Epithelium Pathology in Age-Related Macular Degeneration Mouse Models. AMD, RPE, SRT
14  2018 A convenient protocol for establishing a human cell culture model of the outer retina. RPE
15  2018 Alterations in Extracellular Matrix/Bruch's Membrane Can Cause the Activation of the Alternative Complement Pathway via Tick-Over. AMD, ECM, RPE
16  2018 Amyloid beta deposition related retinal pigment epithelium cell impairment and subretinal microglia activation in aged APPswePS1 transgenic mice. APP, Iba1, NTG, RPE, TEM, ZO-1
17  2018 Bruch's Membrane Compartmentalizes Complement Regulation in the Eye with Implications for Therapeutic Design in Age-Related Macular Degeneration. AMD
18  2018 Calcified nodules in retinal drusen are associated with disease progression in age-related macular degeneration. AMD, HIRD, OCT, RPE
19  2018 Characterization of Human iPSC-RPE on a Prosthetic Bruch's Membrane Manufactured From Silk Fibroin. BMSF, hiPSC
20  2018 Retinal Basal Laminar Deposits in Complement fH/fP Mouse Model of Dense Deposit Disease. AP, BLamD, DDD, ERG, FH, fP, GBM
21  2018 Thermal Stimulation of the Retina Reduces Bruch's Membrane Thickness in Age Related Macular Degeneration Mouse Models. AMD, FLA, OCT, TEM, TS-R
22  2017 Bioengineered Bruch's-like extracellular matrix promotes retinal pigment epithelial differentiation. ECM, RPE
23  2017 Changes in extracellular matrix cause RPE cells to make basal deposits and activate the alternative complement pathway. AMD, ECM, hf, hfRPE, RPE
24  2017 Complement factor H in AMD: Bridging genetic associations and pathobiology. AMD, CFH, MAC, RPE
25  2017 Ex-vivo models of the Retinal Pigment Epithelium (RPE) in long-term culture faithfully recapitulate key structural and physiological features of native RPE. RPE
26  2017 Serum starvation of ARPE-19 changes the cellular distribution of cholesterol and Fibulin3 in patterns reminiscent of age-related macular degeneration. ACAT, AMD, apoB, CoA, EC, Fib3, RPE, UC
27  2017 The Effect of Retinal Melanin on Optical Coherence Tomography Images. OCT, RPE
28  2016 AMD-like retinopathy associated with intravenous iron. AMD, NSR, RPE
29  2016 Detecting Abeta deposition and RPE cell senescence in the retinas of SAMP8 mice. AMD, ERG, OS, RPE, SAMP8
30  2016 Investigation of the Etiology of Central Serous Chorioretinopathy Using En-Face Optical Coherence Tomography and Indocyanine Green Angiography. CSC, ICGA, OCT
31  2016 Spatial and Spectral Characterization of Human Retinal Pigment Epithelium Fluorophore Families by Ex Vivo Hyperspectral Autofluorescence Imaging. RPE
32  2015 Extracellular Matrix Alterations and Deposit Formation in AMD. AMD, ECM, RPE
33  2014 Age-dependent changes in heparan sulfate in human Bruch's membrane: implications for age-related macular degeneration. AMD, CFH, HS
34  2014 Age-related changes of cystatin C expression and polarized secretion by retinal pigment epithelium: potential age-related macular degeneration links. AD, AGEs, hfRPE
35  2014 Detection of esterified cholesterol in murine Bruch's membrane wholemounts with a perfringolysin O-based cholesterol marker. EC, GFP, PFO
36  2014 Subretinal injection of amyloid-beta peptide accelerates RPE cell senescence and retinal degeneration. AMD, cSLO, ERG, FAF, IL, IS, OS, PFA, RPE
37  2013 Alternative complement pathway deficiency ameliorates chronic smoke-induced functional and morphological ocular injury. AMD, AP, CE, RPE, WT
38  2013 Anti-angiogenic effect of the basement membrane protein nidogen-1 in a mouse model of choroidal neovascularization. BM, CNV, ILM, RPE, WT
39  2012 Adhesion failures determine the pattern of choroidal neovascularization in the eye: a computer simulation study. CNV
40  2012 Alterations in basement membrane immunoreactivity of the diabetic retina in three diabetic mouse models. BM, ILM, IR, IRS-1, STZ
41  2012 Cyclic intensive light exposure induces retinal lesions similar to age-related macular degeneration in APPswe/PS1 bigenic mice. CILE, CNV, OCL, RPE, VEGF
42  2011 A rat model for studying the biological effects of circulating LDL in the choriocapillaris-BrM-RPE complex. AMD, LDL, oxLDL
43  2011 Heat treatment of retinal pigment epithelium induces production of elastic lamina components and antiangiogenic activity. AMD, CC, CNV, PEDF, RPE, TSP-1
44  2011 Lipids, lipoproteins, and age-related macular degeneration. AMD, LDL
45  2011 Passage of low-density lipoproteins through Bruch's membrane and choroid. LDL, PBS, RPE, SEM
46  2009 Aging, age-related macular degeneration, and the response-to-retention of apolipoprotein B-containing lipoproteins. ARMD, CAD, RPE
47  2009 An essential role for RPE-derived soluble VEGF in the maintenance of the choriocapillaris. CC, ERG, GA, RPE
48  2009 Apolipoprotein B-containing lipoproteins in retinal aging and age-related macular degeneration. ARMD, RPE
49  2009 Bruch's membrane and choroidal macrophages in early and advanced age-related macular degeneration. AMD, iNOS
50  2009 Bruch's membrane changes in transgenic mice overexpressing the human biglycan and apolipoprotein b-100 genes. AMD, apoB-100, RPE, TEM
51  2009 Esterified cholesterol is highly localized to Bruch's membrane, as revealed by lipid histochemistry in wholemounts of human choroid. EC-F, UC-F
52  2009 Expression of reverse cholesterol transport proteins ATP-binding cassette A1 (ABCA1) and scavenger receptor BI (SR-BI) in the retina and retinal pigment epithelium. ABCA1, AMD, POS, RCT, RPE, RT-PCR, SR-BI
53  2009 Histochemistry and lipid profiling combine for insights into aging and age-related maculopathy. ARM, EC
54  2008 Lipid and fatty acid profile of the retina, retinal pigment epithelium/choroid, and the lacrimal gland, and associations with adipose tissue fatty acids in human subjects. CEs, LDLs, PLs, RPE
55  2008 Morphometric analysis of lipoprotein-like particle accumulation in aging human macular Bruch's membrane. EL, ICL, LLPs, OCL, RPE
56  2007 Age-related changes in human macular Bruch's membrane as seen by quick-freeze/deep-etch. ARM, EL, ICL, LLPs, OCL, RPE, SGs
57  2007 Comparison of morphology of human macular and peripheral Bruch's membrane in older eyes. LLPs, OTAP, QFDE
58  2006 Distribution of laminins in the developing human eye. BMs, DM, ILM, LN, WG
59  2006 Repetitive nonlethal oxidant injury to retinal pigment epithelium decreased extracellular matrix turnover in vitro and induced sub-RPE deposits in vivo. BrdU, ECM, GFP, HQ, MMP, TIMP
60  2006 Retinal pigment epithelial cells synthesize laminins, including laminin 5, and adhere to them through alpha3- and alpha6-containing integrins. ECM, RPE
61  2005 Increased expression of vascular endothelial growth factor associated with accumulation of lipids in Bruch's membrane of LDL receptor knockout mice. ARM, HF, LDL, pTC
62  2005 Lipoprotein-like particles and cholesteryl esters in human Bruch's membrane: initial characterization. apo, Ch, LLPs
63  2005 Retina expresses microsomal triglyceride transfer protein: implications for age-related maculopathy. apoB, ARM, EC, MTP, RPE
64  2003 Apolipoprotein B in cholesterol-containing drusen and basal deposits of human eyes with age-related maculopathy. apoB, ARM, RPE
65  2003 Basal laminar deposit formation in APO B100 transgenic mice: complex interactions between dietary fat, blue light, and vitamin E. BLD, OTO, TEM
66  2003 Female gender, estrogen loss, and Sub-RPE deposit formation in aged mice. MMP
67  1997 Morphology of early choroidal neovascularisation in age-related macular degeneration: correlation with activity. BsM, CNV, RPE