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■ Abbreviation / Long Form : CAN / canrenone

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Total Number of Papers: 12
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Abbreviation:   CAN  (>> Co-occurring Abbreviation)
Long Form:   canrenone
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No. Year Title Co-occurring Abbreviation
2019 Reliable and easy-to-use LC-MS/MS-method for simultaneous determination of the antihypertensives metoprolol, amlodipine, canrenone and hydrochlorothiazide in patients with therapy-refractory arterial hypertension. AML, BP, DDIs, HCT, MET, PK, SRM, TDM
2009 Aldosterone blockade and left ventricular dysfunction: a systematic review of randomized clinical trials. CIs, EF, EP, MI, RRs, SP
2005 Hypothalamus-pituitary-adrenal hyperactivity in human aging is partially refractory to stimulation by mineralocorticoid receptor blockade. AUCs, DHEA, HPA
2003 Conventional and micellar liquid chromatography method development for danazol and validation in capsules. CLC, DZ, MLC
2002 The stimulatory effect of canrenoate, a mineralocorticoid antagonist, on the activity of the hypothalamus-pituitary-adrenal axis is abolished by alprazolam, a benzodiazepine, in humans. DHEA, GABA, HPA, MR
2001 Mineralocorticoid receptor blockade by canrenoate increases both spontaneous and stimulated adrenal function in humans. AVP, DHEA, HPA, MR
1994 Binding of spironolactone metabolites in vivo to renal mineralocorticoid receptors in guinea pigs. SL, TH, TM
1994 Hepatic metabolism of spironolactone. Production of 3-hydroxy-thiomethyl metabolites. SP, TM
1993 Identification of spironolactone metabolites in plasma and target organs of guinea pigs. SL, TH, TM
10  1990 [Pharmacokinetics in healthy subjects of althiazide and spironolactone in a fixed combination for 2 doses]. ALT, MRT, SPI
11  1988 Difference in metabolic profile of potassium canrenoate and spironolactone in the rat: mutagenic metabolites unique to potassium canrenoate. PC, SP
12  1983 Metabolism of spirolactones by the rat testis in vitro. DHC, SPIR