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■ Abbreviation / Long Form : CCT / chaperonin containing TCP-1

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Total Number of Papers: 58
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Abbreviation:   CCT  (>> Co-occurring Abbreviation)
Long Form:   chaperonin containing TCP-1
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No. Year Title Co-occurring Abbreviation
2019 HNRNP Q suppresses polyglutamine huntingtin aggregation by post-transcriptional regulation of vaccinia-related kinase 2. hnRNP Q, TRiC, VRK2
2019 TRiC/CCT chaperonins are essential for organ growth by interacting with insulin/TOR signaling in Drosophila. ---
2018 Elucidation of Therapeutic Peptide Binding Partners from Isolated Mitochondria. biotin-CT20p, SDS-PAGE
2018 Mutation in the Zebrafish cct2 Gene Leads to Abnormalities of Cell Cycle and Cell Death in the Retina: A Model of CCT2-Related Leber Congenital Amaurosis. dpf, LCA
2018 The structure and evolution of eukaryotic chaperonin-containing TCP-1 and its mechanism that folds actin into a protein spring. LECA
2017 PSMA-Targeted Theranostic Nanocarrier for Prostate Cancer. ---
2017 Targeting chaperonin containing TCP1 (CCT) as a molecular therapeutic for small cell lung cancer. SCLC
2016 Chaperonin Containing TCP-1 Protein Level in Breast Cancer Cells Predicts Therapeutic Application of a Cytotoxic Peptide. ---
2015 Expression, purification, crystallization and X-ray diffraction studies of the molecular chaperone prefoldin from Homo sapiens. PFD
10  2015 Structures of the Gbeta-CCT and PhLP1-Gbeta-CCT complexes reveal a mechanism for G-protein beta-subunit folding and Gbetagamma dimer assembly. PhLP1
11  2014 Caenorhabditis elegans chaperonin CCT/TRiC is required for actin and tubulin biogenesis and microvillus formation in intestinal epithelial cells. ---
12  2014 Chaperonin-containing TCP-1 complex directly binds to the cytoplasmic domain of the LOX-1 receptor. oxLDL
13  2012 Chaperone-mediated assembly of G protein complexes. PhLP1
14  2012 Comprehensive mapping of the bull sperm surface proteome. ---
15  2012 Exploring the role of topological frustration in actin refolding with molecular simulations. PFD
16  2012 New insights into the functions and localization of nuclear CCT protein complex in K562 leukemia cells. BN-PAGE
17  2011 Involvement of multimeric protein complexes in mediating the capacitation-dependent binding of human spermatozoa to homologous zonae pellucidae. BN-PAGE
18  2010 Association of the influenza virus RNA polymerase subunit PB2 with the host chaperonin CCT. FKBP5, STIP1
19  2010 Equivalent mutations in the eight subunits of the chaperonin CCT produce dramatically different cellular and gene expression phenotypes. ---
20  2010 Proteomic analysis reveals CCT is a target of Fragile X mental retardation protein regulation in Drosophila. dFMRP, FMRP, FXS
21  2010 Sirt1’s beneficial roles in neurodegenerative diseases - a chaperonin containing TCP-1 (CCT) connection? ---
22  2010 Subunits of the chaperonin CCT interact with F-actin and influence cell shape and cytoskeletal assembly. ---
23  2009 Activities of the chaperonin containing TCP-1 (CCT): implications for cell cycle progression and cytoskeletal organisation. ---
24  2009 Global analysis of protein damage by the lipid electrophile 4-hydroxy-2-nonenal. HNE
25  2009 p90 ribosomal S6 kinase and p70 ribosomal S6 kinase link phosphorylation of the eukaryotic chaperonin containing TCP-1 to growth factor, insulin, and nutrient signaling. MAPK, PI3K, S6K
26  2009 The role of molecular chaperones in human misfolding diseases. TRiC
27  2009 Yeast phosducin-like protein 2 acts as a stimulatory co-factor for the folding of actin by the chaperonin CCT via a ternary complex. ---
28  2008 Development of free-energy-based models for chaperonin containing TCP-1 mediated folding of actin. ---
29  2008 Prefoldin 6 is required for normal microtubule dynamics and organization in Arabidopsis. PFD
30  2008 The interaction network of the chaperonin CCT. ---
31  2008 The structure of CCT-Hsc70 NBD suggests a mechanism for Hsp70 delivery of substrates to the chaperonin. ---
32  2007 Down-regulation of glutaminase C in human hepatocarcinoma cell by diphenylarsinic acid, a degradation product of chemical warfare agents. ALDH1, DPAA, GAC, PAG
33  2006 Characterization of the cytoplasmic chaperonin containing TCP-1 from the Antarctic fish Notothenia coriiceps. ---
34  2005 Sequential ATP-induced allosteric transitions of the cytoplasmic chaperonin containing TCP-1 revealed by EM analysis. ---
35  2005 Unfolding energetics of G-alpha-actin: a discrete intermediate can be re-folded to the native state by CCT. ---
36  2004 Identification of chaperonin CCT gamma subunit as a determinant of retinotectal development by whole-genome subtraction cloning from zebrafish no tectal neuron mutant. RDA, RGC, TMP
37  2003 The cytosolic chaperonin CCT associates to cytoplasmic microtubular structures during mammalian spermiogenesis and to heterochromatin in germline and somatic cells. ---
38  2001 Microtubule cytoskeleton perturbation induced by taxol and colchicine affects chaperonin containing TCP-1 (CCT) subunit gene expression in Tetrahymena cells. ---
39  2001 Nested allosteric interactions in the cytoplasmic chaperonin containing TCP-1. ---
40  2000 Defining the eukaryotic cytosolic chaperonin-binding sites in human tubulins. ---
41  2000 Individual subunits of the eukaryotic cytosolic chaperonin mediate interactions with binding sites located on subdomains of beta-actin. ---
42  2000 Upregulation of cytosolic chaperonin CCT subunits during recovery from chemical stress that causes accumulation of unfolded proteins. ---
43  1999 Eukaryotic type II chaperonin CCT interacts with actin through specific subunits. ---
44  1999 Structures and co-regulated expression of the genes encoding mouse cytosolic chaperonin CCT subunits. ---
45  1999 The cytosolic class II chaperonin CCT recognizes delineated hydrophobic sequences in its target proteins. ---
46  1999 Transcriptional activation of mouse cytosolic chaperonin CCT subunit genes by heat shock factors HSF1 and HSF2. HSFs
47  1998 The chaperone cofactor Hop/p60 interacts with the cytosolic chaperonin-containing TCP-1 and affects its nucleotide exchange and protein folding activities. ---
48  1998 The chaperonin containing TCP-1 (CCT) displays a single-ring mediated disassembly and reassembly cycle. ---
49  1997 Developmental and light-dependent changes of the cytosolic chaperonin containing TCP-1 (CCT) subunits in maize seedlings, and the localization in coleoptiles. ---
50  1997 Subunit characterization of the Caenorhabditis elegans chaperonin containing TCP-1 and expression pattern of the gene encoding CCT-1. ---
51  1997 Tissue-specific subunit of the mouse cytosolic chaperonin-containing TCP-1. ---
52  1996 Analysis of chaperonin-containing TCP-1 subunits in the human keratinocyte two-dimensional protein database: further characterisation of antibodies to individual subunits. ---
53  1996 Cloning and expression of Xenopus CCT gamma, a chaperonin subunit developmentally regulated in neural-derived and myogenic lineages. ---
54  1996 Cofactor A is a molecular chaperone required for beta-tubulin folding: functional and structural characterization. ---
55  1996 Peptide mass fingerprinting of chaperonin-containing TCP-1 (CCT) and copurifying proteins. ---
56  1995 Antibody characterisation of two distinct conformations of the chaperonin-containing TCP-1 from mouse testis. ---
57  1995 Molecular analysis of Caenorhabditis elegans tcp-1, a gene encoding a chaperonin protein. Ce
58  1995 The chaperonin containing t-complex polypeptide 1 (TCP-1). Multisubunit machinery assisting in protein folding and assembly in the eukaryotic cytosol. RBP, TCP-1, TF55