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■ Abbreviation / Long Form : CDA / calcium-dependent antibiotic

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Total Number of Papers: 39
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Abbreviation:   CDA  (>> Co-occurring Abbreviation)
Long Form:   calcium-dependent antibiotic
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No. Year Title Co-occurring Abbreviation
2019 Genome-wide analysis of the role of the antibiotic biosynthesis regulator AbsA2 in Streptomyces coelicolor A3(2). ---
2018 SCO5351 is a pleiotropic factor that impacts secondary metabolism and morphological development in Streptomyces coelicolor. ACT
2017 Metabolic engineering of Streptomyces coelicolor for enhanced prodigiosins (RED) production. ACT, BGCs
2017 Metabolic perturbation to enhance polyketide and nonribosomal peptide antibiotic production using triclosan and ribosome-targeting drugs. NRP
2015 Effects of simulated microgravity and spaceflight on morphological differentiation and secondary metabolism of Streptomyces coelicolor A3(2). ACT, CPK, MMY, SMG
2015 Tryptophan promotes morphological and physiological differentiation in Streptomyces coelicolor. qRT-PCR
2013 An efficient procedure for marker-free mutagenesis of S. coelicolor by site-specific recombination for secondary metabolite overproduction. ACT
2013 Crystal structures of the first condensation domain of CDA synthetase suggest conformational changes during the synthetic cycle of nonribosomal peptide synthetases. NRPSs
2013 The ROK family regulator Rok7B7 pleiotropically affects xylose utilization, carbon catabolite repression, and antibiotic production in streptomyces coelicolor. CCR
10  2012 Crp is a global regulator of antibiotic production in streptomyces. ACT, crp
11  2012 Identification of glucose kinase-dependent and -independent pathways for carbon control of primary metabolism, development and antibiotic production in Streptomyces coelicolor by quantitative proteomics. CCR, Glk
12  2012 Introduction of a non-natural amino acid into a nonribosomal peptide antibiotic by modification of adenylation domain specificity. NRPS
13  2012 Tryptophan catabolism via kynurenine production in Streptomyces coelicolor: identification of three genes coding for the enzymes of tryptophan to anthranilate pathway. KFA, KYN, TDO
14  2011 An orphan histidine kinase, OhkA, regulates both secondary metabolism and morphological differentiation in Streptomyces coelicolor. ACCase, ACT, HK, malonyl-CoA, MS, RT-PCR
15  2010 Deletion of the elongation factor 4 gene (lepA) in Streptomyces coelicolor enhances the production of the calcium-dependent antibiotic. ---
16  2010 Repression of antibiotic production and sporulation in Streptomyces coelicolor by overexpression of a TetR family transcriptional regulator. ACT
17  2009 afsQ1-Q2-sigQ is a pleiotropic but conditionally required signal transduction system for both secondary metabolism and morphological development in Streptomyces coelicolor. ACT, MM
18  2008 Biosynthesis and genetic engineering of lipopeptide antibiotics related to daptomycin. NRPS
19  2008 Harnessing the chemical activation inherent to carrier protein-bound thioesters for the characterization of lipopeptide fatty acid tailoring enzymes. ACP
20  2008 Non-ribosomal peptide synthetase module fusions to produce derivatives of daptomycin in Streptomyces roseosporus. NRPSs
21  2007 An asparagine oxygenase (AsnO) and a 3-hydroxyasparaginyl phosphotransferase (HasP) are involved in the biosynthesis of calcium-dependent lipopeptide antibiotics. AsnO, HasP
22  2007 Mechanistic and structural basis of stereospecific Cbeta-hydroxylation in calcium-dependent antibiotic, a daptomycin-type lipopeptide. ---
23  2007 Stereospecific enzymatic transformation of alpha-ketoglutarate to (2S,3R)-3-methyl glutamate during acidic lipopeptide biosynthesis. 3-MeGlu, alpha-KG, SAM
24  2006 Combinatorial biosynthesis of lipopeptide antibiotics in Streptomyces roseosporus. NRPS
25  2006 Heterologous production of daptomycin in Streptomyces lividans. ---
26  2006 The lipopeptide antibiotic A54145 biosynthetic gene cluster from Streptomyces fradiae. NRPS
27  2005 Fluorescence resonance energy transfer as a probe of peptide cyclization catalyzed by nonribosomal thioesterase domains. FRET, NRPS, TE, Tyc
28  2005 Natural products to drugs: daptomycin and related lipopeptide antibiotics. ---
29  2004 Active-site modifications of adenylation domains lead to hydrolysis of upstream nonribosomal peptidyl thioester intermediates. NRPS
30  2004 Chemo- and regioselective peptide cyclization triggered by the N-terminal fatty acid chain length: the recombinant cyclase of the calcium-dependent antibiotic from Streptomyces coelicolor. CoA, SNAC
31  2004 Metabolic flux analysis for calcium dependent antibiotic (CDA) production in Streptomyces coelicolor. ---
32  2004 Synthesis and derivatization of daptomycin: a chemoenzymatic route to acidic lipopeptide antibiotics. NRPS
33  2002 Activation of antibiotic biosynthesis by specified mutations in the rpoB gene (encoding the RNA polymerase beta subunit) of Streptomyces lividans. ACT
34  2002 Regulation of the Streptomyces coelicolor calcium-dependent antibiotic by absA, encoding a cluster-linked two-component system. ---
35  2002 Structure, biosynthetic origin, and engineered biosynthesis of calcium-dependent antibiotics from Streptomyces coelicolor. ---
36  2001 Genetic and transcriptional analysis of absA, an antibiotic gene cluster-linked two-component system that regulates multiple antibiotics in Streptomyces coelicolor. phospho-AbsA2
37  1998 Physical identification of a chromosomal locus encoding biosynthetic genes for the lipopeptide calcium-dependent antibiotic (CDA) of Streptomyces coelicolor A3(2). ---
38  1996 afsR is a pleiotropic but conditionally required regulatory gene for antibiotic production in Streptomyces coelicolor A3(2). ACT, Red
39  1983 CDA is a new chromosomally-determined antibiotic from Streptomyces coelicolor A3(2). ---