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■ Abbreviation / Long Form : CLP / cecal ligation and puncture

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Total Number of Papers: 2405
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Abbreviation:   CLP  (>> Co-occurring Abbreviation)
Long Form:   cecal ligation and puncture
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No. Year Title Co-occurring Abbreviation
2019 A novel role for programmed cell death receptor ligand 2 in sepsis-induced hepatic dysfunction. PD
2019 Acetic acid alleviates the inflammatory response and liver injury in septic mice by increasing the expression of TRIM40. NF-kappaB, TLR, TRIM
2019 Adipose-derived mesenchymal stem cells ameliorate the inflammatory reaction in CLP-induced septic acute lung injury rats via sTNFR1. ADMSCs, ALI, IL-10, SC, siRNA, sTNFR1
2019 alpha-Mangostin suppresses NLRP3 inflammasome activation via promoting autophagy in LPS-stimulated murine macrophages and protects against CLP-induced sepsis in mice. ALT, AST, Cr, IFN-gamma, IL-10, IL-1beta, LPS, TNF-alpha
2019 Ameliorative effect of gossypin against acute lung injury in experimental sepsis model of rats. ALI, GOS, NF-kappaB
2019 Amitriptyline Treatment Mitigates Sepsis-Induced Tumor Necrosis Factor Expression and Coagulopathy. AMIT
2019 Application of Deacetylated Poly-N-Acetyl Glucosamine Nanoparticles for the Delivery of miR-126 for the Treatment of Cecal Ligation and Puncture-Induced Sepsis. DEAC-pGlcNAc, miR-126
2019 Attenuation of Sepsis-Induced Cardiomyopathy by Regulation of MicroRNA-23b Is Mediated Through Targeting of MyD88-Mediated NF-kappaB Activation. LPS, miR-23b, qPCR
2019 Autophagy Activation Improves Lung Injury and Inflammation in Sepsis. ALI/ARDS, Baf, BALF, CQ, HMGB, IL, LAMP2, LC3II, MCP, MPO, PMN, TNF
10  2019 Basophil-derived tumor necrosis factor can enhance survival in a sepsis model in mice. TNF
11  2019 beta-Casomorphin-7 Ameliorates Sepsis-Induced Acute Kidney Injury by Targeting NF-kappaB Pathway. AKI, beta-CM-7, BUN, Cre, IL-10, KIM-1, MDA, NF, NGAL, SOD, TNF-alpha
12  2019 Biological effects of autophagy in mice with sepsis-induced acute kidney injury. AKI, BUN, Cr
13  2019 Bone Marrow Cells Transplant in Septic Mice Modulates Systemic Inflammatory Response via Cell-Cell Contact. BMDMCs
14  2019 Budding Uninhibited by Benzimidazole-1 Insufficiency Prevents Acute Renal Failure in Severe Sepsis by Maintaining Anticoagulant Functions of Vascular Endothelial Cells. ARF, Bub1, Bub1, HAEC, LPS, siBub1, TF, TM
15  2019 Chemically synthesized Secoisolariciresinol diglucoside (LGM2605) improves mitochondrial function in cardiac myocytes and alleviates septic cardiomyopathy. OCR, ROS, SDG
16  2019 Delayed Remote Ischemic Preconditioning ConfersRenoprotection against Septic Acute Kidney Injury via Exosomal miR-21. AKI, HIF-1alpha, LPS, MTECs, RIPC
17  2019 Dexmedetomidine Attenuates Lung Injury by Promoting Mitochondrial Fission and Oxygen Consumption. ---
18  2019 Dihydromyricetin Alleviates Sepsis-Induced Acute Lung Injury through Inhibiting NLRP3 Inflammasome-Dependent Pyroptosis in Mice Model. ALI, BALF, DHM, IL, MPO
19  2019 Downregulation of TIMP2 attenuates sepsis-induced AKI through the NF-kappab pathway. AKI, HK-2, LPS, NF, TIMP2
20  2019 Effects of early administration of insulin-like growth factor-1 on cognitive function in septic encephalopathy. IGF-1, SE, TNFR
21  2019 Effects of End-Tidal Carbon Dioxide-Guided Fluid Resuscitation on Outcomes in a Cecal Ligation and Puncture Induced Rat Model of Sepsis. CO, FR, MAP, MFI, PSVD
22  2019 Exercise training modifies gut microbiota with attenuated host responses to sepsis in wild-type mice. ---
23  2019 Ferritin Light Chain Confers Protection Against Sepsis-Induced Inflammation and Organ Injury. FTH
24  2019 Glucosamine improves survival in a mouse model of sepsis and attenuates sepsis-induced lung injury and inflammation. GlcN, iNOS, LPS, MAPK, OGA
25  2019 Gpr174-deficient regulatory T cells decrease cytokine storm in septic mice. CTLA-4, GPR174, IL, LPS, TNF-alpha
26  2019 Hepatoprotective Effect of Echinochrome Pigment in Septic Rats. Ech
27  2019 Herpes Virus Entry Mediator (HVEM) Expression Promotes Inflammation/ Organ Injury in Response to Experimental Indirect-Acute Lung Injury. ALI, BALF, HEM, HVEM, iALI
28  2019 Honokiol alleviates sepsis-induced acute kidney injury in mice by targeting the miR-218-5p/heme oxygenase-1 signaling pathway. AKI, GMC, HO-1, LPS, PAS
29  2019 Hydrogen gas inhalation attenuates sepsis-induced liver injury in a FUNDC1-dependent manner. AST, FUDNC1, MODS, RCR
30  2019 Hydrogen gas reduces HMGB1 release in lung tissues of septic mice in an Nrf2/HO-1-dependent pathway. CAT, ELISA, HE, HMGB1, HO-1, IL-10, IL-6, MDA, Nrf2, Nrf2-KO, SOD, TNF-alpha, WT
31  2019 IL-22/IL-22R1 axis is involved in myocardial injury of a mouse cecal ligation and puncture model. ---
32  2019 Increased expression of Toll-like receptors 2, 3, 4 and 7 mRNA in the kidney and intestine of a septic mouse model. TLRs
33  2019 Inhibition of Aerobic Glycolysis Promotes Neutrophil to Influx to The Infectious Site via CXCR2 In Sepsis. 2-DG, ERK, GRK2, LPS
34  2019 Intestinal Microbiota Mediates the Susceptibility to Polymicrobial Sepsis-Induced Liver Injury by Granisetron Generation in Mice. AST, FMT, LPS, p-p38
35  2019 JH-4 reduces HMGB1-mediated septic responses and improves survival rate in septic mice. HMGB1
36  2019 Klotho deficiency aggravates sepsis-related multiple organ dysfunction. AKI
37  2019 Lactobacillus rhamnosus GG treatment improves intestinal permeability and modulates microbiota dysbiosis in an experimental model of sepsis. LGG
38  2019 LDK378 improves micro- and macro-circulation via alleviating STING-mediated inflammatory injury in a Sepsis rat model induced by Cecal ligation and puncture. MAP, TBK1
39  2019 Methane alleviates sepsis-induced injury by inhibiting pyroptosis and apoptosis in vivo and in vitro experiments. ATP, LPS, MRM, MRS, NLRP
40  2019 Milk fat globule-epidermal growth factor 8 (MFG-E8) attenuates sepsis-induced acute kidney injury by inhibiting NF-kappaB signaling pathway1. MFG-E8, rmMFG-E8, SAKI
41  2019 miR-146a targeted to splenic macrophages prevents sepsis-induced multiple organ injury. LPS, miRNAs, NF-kappaB
42  2019 Necrostatin-1 accelerates time to death in a rat model of cecal ligation and puncture and massively increases hepatocyte caspase-3 cleavage. Nec-1
43  2019 NLRP3/Caspase-1 Pathway-Induced Pyroptosis Mediated Cognitive Deficits in a Mouse Model of Sepsis-Associated Encephalopathy. NLRP3, SAE
44  2019 Novel Chitohexaose Analog Protects Young and Aged mice from CLP Induced Polymicrobial Sepsis. CFU, CRP
45  2019 Oxidative stress in the choroid plexus contributes to blood-cerebrospinal fluid barrier disruption during sepsis development. BCSFB, CP, N/N
46  2019 Pelargonidin Protects Against Renal Injury in a Mouse Model of Sepsis. BUN, GSH-Px, PEL, SOD
47  2019 Peroxiredoxin 6 knockout aggravates cecal ligation and puncture-induced acute lung injury. ALI, BALF, CAT, GSH-Px, IL, MDA, MMP, MPO, NF, PRDX, SOD, T-AOC, XOD
48  2019 Phagocytosis by Fibrocytes as a Mechanism to Decrease Bacterial Burden and Increase Survival in Sepsis. ---
49  2019 Probenecid Relieves Cerebral Dysfunction of Sepsis by Inhibiting Pannexin 1-Dependent ATP Release. IL, Panx1, PRB, TNF-alpha
50  2019 Protective Effect of Hesperidin Against Sepsis-Induced Lung Injury by Inducing the Heat-Stable Protein 70 (Hsp70)/Toll-Like Receptor 4 (TLR4)/ Myeloid Differentiation Primary Response 88 (MyD88) Pathway. Hsp70, MyD88, TLR4
51  2019 Protective effects of carbon monoxide releasing molecule‑2 on pancreatic function in septic mice. CO, MPO
52  2019 Protective effects of PNU‑282987 on sepsis‑induced acute lung injury in mice. BALF, LPS
53  2019 Rapid onset of severe septic shock in the pregnant mouse†. LPS
54  2019 Rg6, a rare ginsenoside, inhibits systemic inflammation through the induction of interleukin-10 and microRNA-146a. BMDMs, IL, LPS, TLR
55  2019 Sepsis Induced by Cecal Ligation and Puncture. ---
56  2019 Short-Term Effects of Sepsis and the Impact of Aging on the Transcriptional Profile of Different Brain Regions. SAE
57  2019 SIRT1 activation by butein attenuates sepsis-induced brain injury in mice subjected to cecal ligation and puncture via alleviating inflammatory and oxidative stress. SIRT1
58  2019 Sodium Butyrate Ameliorates Intestinal Injury and Improves Survival in a Rat Model of Cecal Ligation and Puncture-Induced Sepsis. HDAC
59  2019 Suppressive activities of KC1-3 on HMGB1-mediated septic responses. HMGB1, HUVECs, LPS
60  2019 Suppressive Effects of Ginsenoside Rh1 on HMGB1-Mediated Septic Responses. ERK, HMGB1, HUVECs, IL, LPS, NF, TNF
61  2019 Tanshinone IIA attenuates sepsis-induced immunosuppression and improves survival rate in a mice peritonitis model. IL, TSN
62  2019 The inhibitor of interleukin-3 receptor protects against sepsis in a rat model of cecal ligation and puncture. IL-10, IL-1beta, IL-3, IL-6, JAK2, MAP, STAT5, TNF-alpha
63  2019 The Protective Effects and the Involved Mechanisms of Tanshinone IIA on Sepsis-Induced Brain Damage in Mice. DEX group, Sham group
64  2019 Ulinastatin attenuates liver injury and inflammation in a cecal ligation and puncture induced sepsis mouse model. UTI
65  2019 Urotensin receptors as a new target for CLP induced septic lung injury in mice. UII, UTR
66  2019 [beta1 receptor blocker decreases the myocardial inflammation in the sepsis adult rats through inhibition of TLR4/NF-KappaB signaling pathway]. CI, cTnI, E5564 group, ELISA, ES group, IL-1beta, S group, TNF-alpha
67  2019 [Blockade of programmed death-ligand 1 attenuates indirect acute lung injury in mice through targeting endothelial cells but not epithelial cells]. BALF, ELISA, iALI, IL-6, MCP-1, MIP-2, MPO, PBS, PD-L1, siRNA, TNF-alpha
68  2019 [Effects of histone methyltransferase inhibitor on the polarization of peritoneal macrophages in septic mice]. 3-DZNeP, HE, IL-6, iNOS, PPARgamma, Sham group, TNF-alpha
69  2019 [Protective effects of Klotho protein on acute kidney injury in septic mice and its mechanism]. AKI, Cyt C, HE, MDA, NOS, SCr, Sham group
70  2019 [Study on the expression and roles of nucleolin in cardiac injury in septic mice]. CK-MB, cTnI, MDA, ROS, Tg mice
71  2018 6% Hydroxyethyl starch (HES 130/0.4) diminishes glycocalyx degradation and decreases vascular permeability during systemic and pulmonary inflammation in mice. LPS
72  2018 A cold-inducible RNA-binding protein (CIRP)-derived peptide attenuates inflammation and organ injury in septic mice. CIRP
73  2018 A disintegrin and metalloproteinase 15-mediated glycocalyx shedding contributes to vascular leakage during inflammation. ADAM15, ECs, LPS, TER
74  2018 A Novel Mechanism of Mesenchymal Stromal Cell-Mediated Protection against Sepsis: Restricting Inflammasome Activation in Macrophages by Increasing Mitophagy and Decreasing Mitochondrial ROS. BMDMs, BMSCs, ICU, MSCs
75  2018 Accelerated Autophagy of Cecal Ligation and Puncture-Induced Myocardial Dysfunction and Its Correlation with Mammalian Target of Rapamycin Pathway in Rats. LC3-II, mTOR, p-mTOR, PS6K1, SHAM
76  2018 Activation of AMP-Activated Protein Kinase by A769662 Ameliorates Sepsis-Induced Acute Lung Injury in Adult Mice. AMPK, LC
77  2018 Activation of Central Alpha 7 Nicotinic Acetylcholine Receptor Reverses Suppressed Immune Function of T Lymphocytes and Protects Against Sepsis Lethality. alpha7nAChR, CAP, ICU, Th
78  2018 Activation of M1 macrophages in sepsis-induced acute kidney injury in response to heparin-binding protein. Arg-1, HBP, IL-6, iNOS, TNF-alpha
79  2018 Adiponectin alleviates blood hypercoagulability via inhibiting endothelial cell apoptosis induced by oxidative stress in septic rats. APTT, MDA, PT, TF
80  2018 Adiponectin is protective against endoplasmic reticulum stress-induced apoptosis of endothelial cells in sepsis. CHOP, ER, HUVECs, IRE1alpha, LPS, MDA, ROS
81  2018 Adipose-derived mesenchymal stem cell-derived exosomes alleviate overwhelming systemic inflammatory reaction and organ damage and improve outcome in rat sepsis syndrome. ADMSC, SC, SS
82  2018 Alterations in hypothalamic synaptophysin and death markers may be associated with vasopressin impairment in sepsis survivor rats. AVP
83  2018 Amantadine attenuates sepsis-induced cognitive dysfunction possibly not through inhibiting toll-like receptor 2. TLR2, TLRs
84  2018 Angiotensin-(1-7) attenuates organ injury and mortality in rats with polymicrobial sepsis. Ang
85  2018 Annexin A1 Mimetic Peptide AC2-26 Inhibits Sepsis-induced Cardiomyocyte Apoptosis through LXA4/PI3K/AKT Signaling Pathway. ANXA1, HE, LXA4, PI3K, TEM, TUNEL
86  2018 Anti-sepsis protection of Xuebijing injection is mediated by differential regulation of pro- and anti-inflammatory Th17 and T regulatory cells in a murine model of polymicrobial sepsis. XBJ
87  2018 Antiseptic Activity of Ethnomedicinal Xuebijing Revealed by the Metabolomics Analysis Using UHPLC-Q-Orbitrap HRMS. MVA, XBJ
88  2018 Apelin protects against sepsis‑induced cardiomyopathy by inhibiting the TLR4 and NLRP3 signaling pathways. NLRP3, SICM, TLR4
89  2018 Assessment of clinical sepsis-associated biomarkers in a septic mouse model. IL, MIP
90  2018 Atorvastatin and diacerein reduce insulin resistance and increase disease tolerance in rats with sepsis. G6Pase
91  2018 Azithromycin in Combination with Ceftriaxone Reduces Systemic Inflammation and Provides Survival Benefit in a Murine Model of Polymicrobial Sepsis. IL-6, MPO
92  2018 B-1a cells protect mice from sepsis-induced acute lung injury. ALI, ARDS, MPO
93  2018 Berberine Exerts a Protective Effect on Gut-Vascular Barrier via the Modulation of the Wnt/Beta-Catenin Signaling Pathway During Sepsis. AJ, GVB, LPS, RIMECs, TEER, TJ
94  2018 BML-111 Reduces Neuroinflammation and Cognitive Impairment in Mice With Sepsis via the SIRT1/NF-kappaB Signaling Pathway. IL, SIRT1, TNF-alpha
95  2018 BMSCs ameliorate septic coagulopathy by suppressing inflammation in cecal ligation and puncture-induced sepsis. BMSC, LPS
96  2018 Body temperature and mouse scoring systems as surrogate markers of death in cecal ligation and puncture sepsis. M-CASS, MGS, MSS
97  2018 Brain-Defective Insulin Signaling Is Associated to Late Cognitive Impairment in Post-Septic Mice. CREB, CREBpSer133, GluA1pSer845, IA, IRS-1pSer636, NOR, TNF-alpha
98  2018 Cannabinoid CB1 Receptor Antagonist Rimonabant Decreases Levels of Markers of Organ Dysfunction and Alters Vascular Reactivity in Aortic Vessels in Late Sepsis in Rats. AVP
99  2018 Cardioprotective and functional effects of levosimendan and milrinone in mice with cecal ligation and puncture-induced sepsis. LV
100  2018 Cardioprotective effects of irbesartan in polymicrobial sepsis : The role of the p38MAPK/NF-kappaB signaling pathway. cTnI, IL, LV, MCP-1, NF, TNF