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■ Abbreviation / Long Form : CN / calcineurin

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Total Number of Papers: 322
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Abbreviation:   CN  (>> Co-occurring Abbreviation)
Long Form:   calcineurin
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No. Year Title Co-occurring Abbreviation
2019 Calcineurin inhibitors reduce NFAT-dependent expression of antifungal pentraxin-3 by human monocytes. ---
2019 Expression of calcineurin in relation to the embryonic diapause process in the silkworm, Bombyx mori. CNA
2019 Identification of a targeting-delivery peptide based on rhCNB. CnB, rhCNB
2019 Impaired Cu-Zn Superoxide Dismutase (SOD1) and Calcineurin (Cn) Interaction in ALS: A Presumed Consequence for TDP-43 and Zinc Aggregation in Tg SOD1G93A Rodent Spinal Cord Tissue. ALS, Ser, Zn
2019 Neurite atrophy and apoptosis mediated by PERK signaling after accumulation of GM2-ganglioside. CHOP, ER, PKR, UPR
2018 A novel research model for evaluating sunscreen protection in the UV-A1. HDF-N, UVR
2018 AKAP150 involved in paclitaxel-induced neuropathic pain via inhibiting CN/NFAT2 pathway and downregulating IL-4. AKAP150, DRG, IL-4, NFAT2
2018 Alzheimer's Disease, Dendritic Spines, and Calcineurin Inhibitors: A New Approach? AD
2018 Astrocyte Activation and the Calcineurin/NFAT Pathway in Cerebrovascular Disease. NFATs
10  2018 Ca2+, Astrocyte Activation and Calcineurin/NFAT Signaling in Age-Related Neurodegenerative Diseases. ADs, TBI
11  2018 Calcineurin B in CD4+ T Cells Prevents Autoimmune Colitis by Negatively Regulating the JAK/STAT Pathway. NFAT
12  2018 Calcineurin: directing the damage in Alzheimer disease: An Editorial for 'Neuronal calcineurin transcriptional targets parallel changes observed in Alzheimer disease brain' on page 24. AD
13  2018 Cyclosporine A-Mediated IL-6 Expression Promotes Neural Induction in Pluripotent Stem Cells. CsA, PSCs
14  2018 Isx9 Regulates Calbindin D28K Expression in Pancreatic beta Cells and Promotes beta Cell Survival and Function. CREB, D28K, NFAT
15  2018 Neuronal calcineurin transcriptional targets parallel changes observed in Alzheimer disease brain. AD
16  2018 Paxillin-Mediated Recruitment of Calcineurin to the Contractile Ring Is Required for the Correct Progression of Cytokinesis in Fission Yeast. CAR
17  2018 Pharmacokinetics and Pharmacodynamics of Once-Daily Tacrolimus Compared With Twice-Daily Tacrolimus in the Early Stage After Living Donor Liver Transplantation. AUC0-24, LDLT, OD, TD
18  2018 Regulator of Calcineurin 1 helps coordinate whole-body metabolism and thermogenesis. NST, RCAN1, SLN
19  2018 TAR DNA Binding Protein-43 Loss of Function Induced by Phosphorylation at S409/410 Blocks Autophagic Flux and Participates in Secondary Brain Injury After Intracerebral Hemorrhage. ICH, SBI, TDP-43
20  2018 The interaction between calcineurin and alpha-synuclein is regulated by calcium and calmodulin. alpha-syn, mDA, NFAT, TG
21  2018 The Transcription Factor NFATc1 Supports the Rejection of Heterotopic Heart Allografts. CsA, NFATs
22  2017 Calcineurin/NFAT Signaling in Activated Astrocytes Drives Network Hyperexcitability in Abeta-Bearing Mice. AD, NFAT4
23  2017 Cyclosporin derivatives inhibit hepatitis B virus entry without interfering with NTCP transporter activity. CsA, Cyps, HBV
24  2017 Identification of three signaling molecules required for calcineurin-dependent monopolar growth induced by the DNA replication checkpoint in fission yeast. MT, NETO
25  2017 Inhibition of calcineurin by FK506 stimulates germinal vesicle breakdown of mouse oocytes in hypoxanthine-supplemented medium. CNA, CnB, DOs, GV, GVBD, HX
26  2017 Mitochondrial stress-induced p53 attenuates HIF-1alpha activity by physical association and enhanced ubiquitination. Glut1-4, HIF-1alpha, mtDNA, MtRS
27  2017 Molecular targeting of cell-permeable peptide inhibits pancreatic ductal adenocarcinoma cell proliferation. C16orf74, DN, PBS, PDAC
28  2017 Peptide 11R-VIVIT stimulates osteoblastogenesis through regulating the expression of nuclear factor of activated T cells cytoplasmic 1. ARS, NFAT, OC, OP, OPN, RC, WT
29  2017 Peptides derived from transcription factor EB bind to calcineurin at a similar region as the NFAT-type motif. NFATc1-YLAVP, TFEB
30  2017 Risk of Myopathy in Patients in Therapy with Statins: Identification of Biological Markers in a Pilot Study. PKCtheta, WB
31  2016 Blockade of Astrocytic Calcineurin/NFAT Signaling Helps to Normalize Hippocampal Synaptic Function and Plasticity in a Rat Model of Traumatic Brain Injury. AAV, CCI
32  2016 Calcineurin and GSK-3 inhibition sensitizes T-cell acute lymphoblastic leukemia cells to apoptosis through X-linked inhibitor of apoptosis protein degradation. GSK-3beta, T-ALL, XIAP
33  2016 Calcineurin beta protects brain after injury by activating the unfolded protein response. GFAP, PERK, TBI, UPR
34  2016 Calcineurin complex isolated from T-cell acute lymphoblastic leukemia (T-ALL) cells identifies new signaling pathways including mTOR/AKT/S6K whose inhibition synergize with calcineurin inhibition to promote T-ALL cell death. T-ALL
35  2016 Cooperative autoinhibition and multi-level activation mechanisms of calcineurin. AID, AIS
36  2016 Discovery of a latent calcineurin inhibitory peptide from its autoinhibitory domain by docking, dynamic simulation, and in vitro methods. AID, HPLC, MD, MM/GBSA
37  2016 Effect of the knockdown of Cabin1 on p53 in glomerular podocyte. Ang II, Cabin1
38  2016 Expression of nuclear factor of activated T cells (NFAT) and downstream muscle-specific proteins in ground squirrel skeletal and heart muscle during hibernation. CaM, DPI, Ea, EC, ELISAs, ER, LA, LT, NFAT
39  2016 Investigating the human Calcineurin Interaction Network using the piɸLxVP SLiM. PSPs, SLiMs
40  2016 Molecular Machines Determining the Fate of Endocytosed Synaptic Vesicles in Nerve Terminals. ARF, Cdk5, SV
41  2016 NFATc1 releases BCL6-dependent repression of CCR2 agonist expression in peritoneal macrophages from Saccharomyces cerevisiae infected mice. IM
42  2016 Phosphoproteomics analyses show subnetwork systems in T-cell receptor signaling. TCR
43  2016 Quercetin targets the interaction of calcineurin with LxVP-type motifs in immunosuppression. CaM, CsA, CyP
44  2016 Resistance to pathologic cardiac hypertrophy and reduced expression of CaV1.2 in Trpc3-depleted mice. BP, Trpc, WT
45  2016 Role of calcineurin (CN) in kidney glomerular podocyte: CN inhibitor ameliorated proteinuria by inhibiting the redistribution of CN at the slit diaphragm. SD
46  2016 Sumoylation-independent activation of Calcineurin-NFAT-signaling via SUMO2 mediates cardiomyocyte hypertrophy. ---
47  2016 Suplatast tosilate alleviates nasal symptoms through the suppression of nuclear factor of activated T-cells-mediated IL-9 gene expression in toluene-2,4-diisocyanate-sensitized rats. H1R, NFAT, TDI
48  2016 The 1p36 Tumor Suppressor KIF 1Bbeta Is Required for Calcineurin Activation, Controlling Mitochondrial Fission and Apoptosis. Drp1
49  2016 The Sur1-Trpm4 channel regulates NOS2 transcription in TLR4-activated microglia. LPS, NFAT, NO, TLR4
50  2016 Yeast Ca(2+)-signal transduction inhibitors isolated from Dominican amber prevent the degranulation of RBL-2H3 cells through the inhibition of Ca(2+)-influx. GSK-3beta, HR, RBL
51  2015 A novel role for an RCAN3-derived peptide as a tumor suppressor in breast cancer. CIC, NFATc, RCAN
52  2015 Binding of calmodulin changes the calcineurin regulatory region to a less dynamic conformation. CaM, FT-IR, ITC
53  2015 Enzymatic and thermodynamic analysis of calcineurin inhibition by RCAN1. DeltaV314, ITC
54  2015 Gq signaling causes glomerular injury by activating TRPC6. FSGS, PAN, TRPC6
55  2015 Identification and characterization of the cDNAs encoding the two subunits of Chinese mitten crab (Eriocheir sinensis) calcineurin: their implications in stress and immune response. ---
56  2015 Identification of small-molecule inhibitors of calcineurin-NFATc signaling that mimic the PxIxIT motif of calcineurin binding partners. CsA
57  2015 Intra-CA1 administration of FK-506 (tacrolimus) in rat impairs learning and memory in an inhibitory avoidance paradigm. IA
58  2015 Neuromodulatory effect of Galphas- or Galphaq-coupled G-protein-coupled receptor on NMDA receptor selectively activates the NMDA receptor/Ca2+/calcineurin/cAMP response element-binding protein-regulated transcriptional coactivator 1 pathway to effectively induce brain-derived neurotrophic factor expression in neurons. CRTC1, IEGs, PACAP, PKA
59  2015 NMR resonance assignments of the catalytic domain of human serine/threonine phosphatase calcineurin in unligated and PVIVIT-peptide-bound states. NFATs
60  2015 Ongoing controversies surrounding cardiac remodeling: is it black and white-or rather fifty shades of gray? CaMKII, PKA
61  2015 RCAN 1 and 3 proteins regulate thymic positive selection. RCAN
62  2015 Strategies to make protein serine/threonine (PP1, calcineurin) and tyrosine phosphatases (PTP1B) druggable: achieving specificity by targeting substrate and regulatory protein interaction sites. PP1
63  2015 The role of three calcineurin subunits and a related transcription factor (Crz1) in conidiation, multistress tolerance and virulence in Beauveria bassiana. MAPK, UV
64  2014 A calcineurin- and NFAT-dependent pathway is involved in alpha-synuclein-induced degeneration of midbrain dopaminergic neurons. CsA, mDA, NFATs, PD
65  2014 Calcineurin Abeta regulates NADPH oxidase (Nox) expression and activity via nuclear factor of activated T cells (NFAT) in response to high glucose. NFAT, NOX
66  2014 Calcineurin activity assay measurement by liquid chromatography-tandem mass spectrometry in the multiple reaction monitoring mode. CNIs, LC-MRM-MS, PBMCs
67  2014 Calcineurin and glial signaling: neuroinflammation and beyond. ---
68  2014 Calcineurin determines toxic versus beneficial responses to alpha-synuclein. ---
69  2014 Calcineurin-mediated YB-1 dephosphorylation regulates CCL5 expression during monocyte differentiation. PMA, Ser-102, YB
70  2014 Calcineurin/Nfatc1 signaling links skin stem cell quiescence to hormonal signaling during pregnancy and lactation. CsA, HF, NFATc1, PRL, PRLR, SC
71  2014 Changing the paradigm for myoglobin: a novel link between lipids and myoglobin. Mb
72  2014 Cloning and characterization of two subunits of calcineurin cDNA in naked carp (Gymnocypris przewalskii) from Lake Qinghai, China. ---
73  2014 Direct evidence for calcineurin binding to the exon-7 loop of the sodium-bicarbonate cotransporter NBCn1. Cn-Is, MTAL, RTA, SPR
74  2014 Excitatory GABA induces BDNF transcription via CRTC1 and phosphorylated CREB-related pathways in immature cortical cells. BDNF, Bdnf-pIV, CaMK, CRE, CRTC1, MAPK
75  2014 FK506 protects against articular cartilage collagenous extra-cellular matrix degradation. ECM, OA
76  2014 miR-23a is decreased during muscle atrophy by a mechanism that includes calcineurin signaling and exosome-mediated export. DEX, miRs, MuRF1, NFATc3
77  2014 Mitochondrial retrograde signaling induces epithelial-mesenchymal transition and generates breast cancer stem cells. EMT, HMECs
78  2014 Pharmacokinetic evaluation of topical calcineurin inhibitors for treatment of allergic conjunctivitis. ---
79  2014 Probing the Ca2+/CaM-induced secondary structural and conformational changes in calcineurin. ---
80  2014 Protein kinase Cepsilon-calcineurin cosignaling downstream of toll-like receptor 4 downregulates fibrosis and induces wound healing gene expression in cardiac myofibroblasts. ChIP, COX-2, CTGF, IL-6, iNOS, LCN2, PKCepsilon, TIMP-1, TLR4
81  2014 Specific calcineurin targeting in macrophages confers resistance to inflammation via MKP-1 and p38. CsA
82  2014 The LxVP and PxIxIT NFAT motifs bind jointly to overlapping epitopes on calcineurin's catalytic domain distant to the regulatory domain. CnA, NFATs
83  2014 The serine-threonine phosphatase calcineurin is a regulator of endothelial store-operated calcium entry. CiP, PAECs, SOC, STIM1, TRPC
84  2014 Towards gene therapy for EBV-associated posttransplant lymphoma with genetically modified EBV-specific cytotoxic T cells. CTLs, EBV, SCT
85  2014 Transient receptor potential channels contribute to pathological structural and functional remodeling after myocardial infarction. MI, TRPC
86  2013 Cyclophilin inhibitors as antiviral agents. CsA, Cyps
87  2013 Identification of alkylbenzene sulfonate surfactants leaching from an acrylonitrile butadiene rubber as novel inhibitors of calcineurin activity. CaM
88  2013 Isogarcinol is a new immunosuppressant. Con A, CsA, DTH, MLR
89  2013 Leukemia-initiating cell activity requires calcineurin in T-cell acute lymphoblastic leukemia. T-ALL
90  2013 Modulation of calcineurin activity in mouse brain by chronic oral administration of cyclosporine A. CsA
91  2013 NFATc3 promotes Ca(2+) -dependent MMP3 expression in astroglial cells. Ast-NSC, BzATP, CsA, IO, MMP-3, NFAT, TIMP
92  2013 Release from meiotic arrest in ascidian eggs requires the activity of two phosphatases but not CaMKII. ---
93  2013 The molecular mechanism of substrate engagement and immunosuppressant inhibition of calcineurin. CsA
94  2013 Trypanosoma cruzi infection and endothelin-1 cooperatively activate pathogenic inflammatory pathways in cardiomyocytes. ANP, COX2, EDN1, ET-1, NFAT, Nppa
95  2013 Voclosporin food effect and single oral ascending dose pharmacokinetic and pharmacodynamic studies in healthy human subjects. PK, VCS
96  2013 [Cnb1 involved in cytokinesis in Schizosaccharomyces pombe]. ---
97  2012 A proteomic interrogation of Cryptococcus neoformans: interaction networks for calcineurin in a heated environment. CnA, CnB
98  2012 Ca(2+) influx through L-type Ca(2+) channels and transient receptor potential channels activates pathological hypertrophy signaling. AFVMs, NFAT, NRVMs, TRP
99  2012 Calcineurin and Akt expression in hypertrophied bladder in STZ-induced diabetic rat. DMC
100  2012 Calcineurin B subunit acts as a potential agent for preventing cardiac ischemia/reperfusion injury. CnB, I/R