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■ Abbreviation / Long Form : CPA / N6-cyclopentyladenosine

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Total Number of Papers: 370
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Abbreviation:   CPA  (>> Co-occurring Abbreviation)
Long Form:   N6-cyclopentyladenosine
 Abbreviation Variation
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No. Year Title Co-occurring Abbreviation
2018 Activation of A1 and A2a adenosine receptors promotes neural progenitor cell proliferation. CNS, DPCPA, ERK, NPCs
2018 Adenosine A1 receptor: A neuroprotective target in light induced retinal degeneration. CI, DPCPX, ERG, GFAP, LIRD, WB
2018 Mechanisms of acetylcholinesterase protection against sarin and soman by adenosine A1 receptor agonist N6-cyclopentyladenosine. ACh, AChE, NAs
2018 Role of transglutaminase 2 in A1 adenosine receptor- and beta2-adrenoceptor-mediated pharmacological pre- and post-conditioning against hypoxia-reoxygenation-induced cell death in H9c2 cells. siRNA, TG2
2017 Electroacupuncture Attenuates CFA-induced Inflammatory Pain by suppressing Nav1.8 through S100B, TRPV1, Opioid, and Adenosine Pathways in Mice. CFA, DRG, EA, EM, GFAP, RAGE, SCDH, TRPV1
2017 Electroacupuncture Attenuates Induction of Inflammatory Pain by Regulating Opioid and Adenosine Pathways in Mice. CFA, EA, EM
2017 Hypothermia in mouse is caused by adenosine A1 and A3 receptor agonists and AMP via three distinct mechanisms. AMP, AR, CHA
2017 Role of A1 and A2A adenosine receptor agonists in adipose tissue inflammation induced by obesity in mice. NECA
2017 Targeting ASIC3 for Relieving Mice Fibromyalgia Pain: Roles of Electroacupuncture, Opioid, and Adenosine. DRG, EA, EM, FM, SC
10  2017 The Adenosine A1 Receptor Antagonist DPCPX Inhibits Tumor Progression via the ERK/JNK Pathway in Renal Cell Carcinoma. A1R, DPCPX, RCC
11  2016 Adenosine-A1 receptor agonist induced hyperalgesic priming type II. MOR, PGE2, PKA
12  2016 Contractile effects and receptor analysis of adenosine-receptors in human detrusor muscle from stable and neuropathic bladders. NECA
13  2016 Evaluation of acetylcholine, seizure activity and neuropathology following high-dose nerve agent exposure and delayed neuroprotective treatment drugs in freely moving rats. ACh
14  2016 The effect of adenosine A1 receptor agonist and antagonist on p53 and caspase 3, 8, and 9 expression and apoptosis rate in MCF-7 breast cancer cell line. DPCPX
15  2015 Caffeine ameliorates hemodynamic derangements and portosystemic collaterals in cirrhotic rats. PH, PP, PSS, VEGF
16  2015 Role of adenosine signaling on pentylenetetrazole-induced seizures in zebrafish. ADA, DPCPX, EHNA, NBTI, NT, PTZ
17  2014 G-protein-coupled inward rectifier potassium current contributes to ventricular repolarization. ACh, APD, KO
18  2014 Interaction of the adenosine A1 receptor agonist N6-cyclopentyladenosine and kappa-opioid receptors in rat spinal cord nociceptive reflexes. ---
19  2014 Purinergic control of hippocampal circuit hyperexcitability in Dravet syndrome. A1R, E/I, FS and aFS, FSLEs, mSMEI, SMEI, VSDI
20  2014 Regulation of Gbetagammai-dependent PLC-beta3 activity in smooth muscle: inhibitory phosphorylation of PLC-beta3 by PKA and PKG and stimulatory phosphorylation of Galphai-GTPase-activating protein RGS2 by PKG. PI, PKA
21  2013 3-Mercaptopropionic acid-induced repetitive seizures increase GluN2A expression in rat hippocampus: a potential neuroprotective role of cyclopentyladenosine. MP, NMDAR
22  2013 GIRK channel activation via adenosine or muscarinic receptors has similar effects on rat atrial electrophysiology. ACh, ERP, GIRK, RMP
23  2013 Interaction of the adenosine A1 receptor agonist N6-cyclopentyladenosine (CPA) and opioid receptors in spinal cord nociceptive reflexes. CPT
24  2013 Nodose ganglia-modulatory effects on respiration. ---
25  2013 [Anticonvulsant and neuroprotective effects of cyclopentyladenosine on the model of convulsive status in rats]. ---
26  2012 Neuromuscular transmission modulation by adenosine upon aging. CADO, ITU, MEPPs
27  2011 Decreased purinergic inhibition of synaptic activity in a mouse model of Niemann-Pick disease type C. fEPSP, LTP, NPC
28  2010 3-mercaptopropionic acid-induced seizures decrease NR2B expression in Purkinje cells: cyclopentyladenosine effect. MP, NMDARs
29  2010 A novel highly selective adenosine A1 receptor agonist VCP28 reduces ischemia injury in a cardiac cell line and ischemia-reperfusion injury in isolated rat hearts at concentrations that do not affect heart rate. SI
30  2010 Adenosinergic modulation of neuronal activity in the pond snail Lymnaea stagnalis. AP, DPCPX
31  2010 Cooperative cardioprotection through adenosine A1 and A2A receptor agonism in ischemia-reperfused isolated mouse heart. A2AKO
32  2010 Differential effects of adenosine A1 receptor on pain-related behavior in normal and nerve-injured rats. A1R, LTP, SNL
33  2009 Cardioprotection induced by adenosine A1 receptor agonists in a cardiac cell ischemia model involves cooperative activation of adenosine A2A and A2B receptors by endogenous adenosine. SI
34  2009 Functional interaction between purinergic system and opioid withdrawal: in vitro evidence. 8-PT, DMPX
35  2009 Protein phosphatase 2A contributes to the cardiac dysfunction induced by endotoxemia. cTnI, LPS, PP2A
36  2009 [Effect of cyclopentyladenosine on the orientation, exploratory, and emotional behavior of rats with model brain injury]. ---
37  2009 [Importance of selective A1 agonists for the protection of brain and heart against injuring factors]. EGTA, NECA
38  2008 Activation of adenosine A1 receptor-induced neural stem cell proliferation via MEK/ERK and Akt signaling pathways. DPCPA, ERK, MEK, NSCs
39  2008 Adenosine A1 receptor activation mediates NMDA receptor activity in a pertussis toxin-sensitive manner during normoxia but not anoxia in turtle cortical neurons. A1R, NMDAR, PTX
40  2008 Adenosine modulates alpha2-adrenergic receptors within specific subnuclei of the nucleus tractus solitarius in normotensive and spontaneously hypertensive rats. A1R, Adr2R, NTS, SHR
41  2008 Effect of n6-cyclopentyladenosine on ouabain-induced toxicity in isolated Guinea pig atria. ---
42  2008 Functional expression of the adenosine A1 receptor in rabbit lacrimal gland. ---
43  2008 Homeostatic action of adenosine A3 and A1 receptor agonists on proliferation of hematopoietic precursor cells. ---
44  2008 Solid lipid microparticles for the stability enhancement of the polar drug N6-cyclopentyladenosine. SLMs
45  2007 A1 adenosine receptor activation promotes angiogenesis and release of VEGF from monocytes. AR, CAM
46  2007 Adenosine deaminase inhibition enhances the inotropic response mediated by A1 adenosine receptor in hyperthyroid guinea pig atrium. ADA, EHNA
47  2007 Differential expression of cerebellar metabotropic glutamate receptors mGLUR2/3 and mGLUR4a after the administration of a convulsant drug and the adenosine analogue cyclopentyladenosine. mGluR, MP
48  2007 Distinct KATP channels mediate the antihypertrophic effects of adenosine receptor activation in neonatal rat ventricular myocytes. AR, ATP, mitoK ATP, PE, sarcK ATP
49  2007 Influence of hyperthyroidism on the effect of adenosine transport blockade assessed by a novel method in guinea pig atria. ADO, NBTI
50  2007 Stimulation of adenosine A1 receptors decreases in vivo dopamine D1 receptor binding of [11C]SCH23390 in the cat striatum revealed by positron emission tomography. PET
51  2006 A novel role for protein phosphatase 2A in receptor-mediated regulation of the cardiac sarcolemmal Na+/H+ exchanger NHE1. ARVM
52  2006 Adenosine inhibits ENaC via cytochrome P-450 epoxygenase-dependent metabolites of arachidonic acid. 11,12-EET, AA, CCD, CHA, CYP, ENaC, MS-PPOH
53  2006 Allosteric modulation, thermodynamics and binding to wild-type and mutant (T277A) adenosine A1 receptors of LUF5831, a novel nonadenosine-like agonist. cAMP, DPCPX, WT
54  2006 Effect of nucleoside transport blockade on the interstitial adenosine level characterized by a novel method in guinea pig atria. ADO, NT, RRM
55  2006 Mechanism of adenosine-induced airways obstruction in allergic guinea pigs. AMP, DPCPX
56  2006 Nanoparticle formulation may affect the stabilization of an antiischemic prodrug. Oct-CPA
57  2006 p38 mitogen-activated protein kinase contributes to adenosine A1 receptor-mediated synaptic depression in area CA1 of the rat hippocampus. MAPK, phospho-p38
58  2006 Polymeric nanoparticles as drug controlled release systems: a new formulation strategy for drugs with small or large molecular weight. BSA, PLA, PLGA
59  2006 Potentiation of adenosine A1 receptor agonist CPA-induced antinociception by paeoniflorin in mice. PF
60  2006 The effect of an adenosine A1 receptor agonist in the treatment of experimental subarachnoid hemorrhage-induced cerebrovasospasm. eNOS, iNOS, NO, SAH
61  2005 Acute effects of guarana (Paullinia cupana Mart.) on mouse behaviour in forced swimming and open field tests. ---
62  2005 Development and characterization of biodegradable nanospheres as delivery systems of anti-ischemic adenosine derivatives. Oct-CPA
63  2005 Effects of single and long-term theophylline treatment on the threshold of mechanical nociception: contribution of adenosine A1 and alpha2-adrenoceptors. ---
64  2005 Enhancement of wind-up by the combined administration of adenosine A1 receptor ligands on spinalized rats with carrageenan-induced inflammation. CPT
65  2005 N6-cyclopentyladenosine inhibits proliferation of murine haematopoietic progenitor cells in vivo. CFC-GM
66  2005 Role of central and peripheral adenosine receptors in the cardiovascular responses to intraperitoneal injections of adenosine A1 and A2A subtype receptor agonists. 8-SPT, CPT, i.p
67  2005 The antinociceptive effects of the systemic adenosine A1 receptor agonist CPA in the absence and in the presence of spinal cord sensitization. ---
68  2004 A1 and A2A adenosine receptor modulation of alpha 1-adrenoceptor-mediated contractility in human cultured prostatic stromal cells. HCPSC, NECA, PE
69  2004 Adenosine receptors involved in modulation of noradrenaline release in isolated rat tail artery. DPCPX, NECA
70  2004 Allosteric modulation and constitutive activity of fusion proteins between the adenosine A1 receptor and different 351Cys-mutated Gi alpha-subunits. CPT, DPCPX
71  2004 Atrial natriuretic peptide modulates the hyperpolarization-activated current (If) in human atrial myocytes. DeltaVh, GC, HuAM, PTX
72  2004 Cardiovascular effects of the adenosine A1 receptor agonist N6-cyclopentyladenosine (CPA) decisive for its therapeutic efficacy in sarin poisoning. ---
73  2004 Comparative analysis of putative agonist-binding modes in the human A1 adenosine receptor. CCPA, LIE, NECA
74  2004 Concentration estimation via curve fitting: quantification of negative inotropic agents by using a simple mathematical method in guinea pig atria. ---
75  2004 Effect of the K+(ATP) channel opener, KCO912, on baseline and allergen induced airway hyperresponsiveness in allergic rabbits. ---
76  2004 Partial A(1) adenosine receptor agonists from a molecular perspective and their potential use as chronic ventricular rate control agents during atrial fibrillation (AF). AF, SAR
77  2004 Pharmacological manipulations of ATP-dependent potassium channels and adenosine A1 receptors do not impact hippocampal ischemic preconditioning in vivo: evidence in a highly quantitative gerbil model. DPCPX
78  2004 Spinal vs. supraspinal antinociceptive activity of the adenosine A(1) receptor agonist cyclopentyl-adenosine in rats with inflammation. ---
79  2003 Activation of adenosine A1 receptor attenuates cardiac hypertrophy and prevents heart failure in murine left ventricular pressure-overload model. CADO, TAC
80  2003 Adenosine A(1) receptor-mediated presynaptic inhibition at the calyx of Held of immature rats. CPT, EPSCs
81  2003 Decrease of adenosine A1 receptor density and of adenosine neuromodulation in the hippocampus of kindled rats. ATP, fEPSP
82  2003 Individual and combined effects of N6-cyclopentyladenosine, flunarizine and diazepam on aminophylline-induced recurrent generalized seizures in mice. AMPH, FLN
83  2003 Involvement of adenosine A1 and A2A receptors in the adenosinergic modulation of the discriminative-stimulus effects of cocaine and methamphetamine in rats. CPT, MSX-3
84  2003 Modulation of protein phosphatase 2a by adenosine A1 receptors in cardiomyocytes: role for p38 MAPK. PP2a
85  2003 Oligodendrocytes express functional A1 adenosine receptors that stimulate cellular migration. A1ARs, NECA, OLGs, OPCs
86  2003 Positive inotropic effect of the inhibition of cyclic GMP-stimulated 3',5'-cyclic nucleotide phosphodiesterase (PDE2) on guinea pig left atria in eu- and hyperthyroidism. ---
87  2003 Pressure effects on the GTPase activity of brain membrane G proteins of deep-living marine fishes. G proteins
88  2003 Rho-kinase inhibition blunts renal vasoconstriction induced by distinct signaling pathways in vivo. GBF, MLC, MLCP, ROK
89  2003 Species comparison of adenosine A1 receptors in isolated mammalian atrial and ventricular myocardium. ADO, ISO, LA, RA
90  2003 Synergistic effects of adenosine A1 and P2Y receptor stimulation on calcium mobilization and PKC translocation in DDT1 MF-2 cells. PKC
91  2003 [Protective effect of A-agonists in a minimum invasive model of spinal cord ischemia in rats]. CHA, SCI
92  2002 A1 adenosine receptor activation induces ventriculomegaly and white matter loss. 8-SPT, A1ARs
93  2002 Adenosine A(3) receptor-mediated potentiation of mucociliary transport and epithelial ciliary motility. IB-MECA
94  2002 Adenosine receptor ligands and cocaine in conditioned place preference (CPP) test in rats. CPP, CPT, NECA
95  2002 Adenosine-mediated cardioprotection in ischemic-reperfused mouse heart. ---
96  2002 Blockade of adenosine A1 receptors in the posterior cingulate cortex facilitates memory in rats. DPCPX
97  2002 Characterization of adenosine receptors mediating the vasodilator effects of adenosine receptor agonists in the microvasculature of the hamster cheek pouch in vivo. 2-CADO, 8-SPT, DPCPX, NECA
98  2002 Cocaine-induced hyperactivity is more influenced by adenosine receptor agonists than amphetamine-induced hyperactivity. NECA
99  2002 Effects of adenosine agonists on consumptive behaviour and body temperature. NECA
100  2002 Effects of adenosine receptor agonists on guinea-pig isolated working hearts and the role of endothelium and NO. L-NOARG, NO, NOS