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■ Abbreviation / Long Form : CYP1A1 / cytochrome P450 1A1

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Total Number of Papers: 760
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Abbreviation:   CYP1A1  (>> Co-occurring Abbreviation)
Long Form:   cytochrome P450 1A1
 Abbreviation Variation
 Long Form Variation
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No. Year Title Co-occurring Abbreviation
2020 Anticancer effects of NSC‑631570 (Ukrain) in head and neck cancer cells: Invitro analysis of growth, invasion, angiogenesis and gene expression. HUVECs
2020 Biochemical properties of human full-length aryl hydrocarbon receptor (AhR). AhR, XRE
2020 Cytochrome P450 1A1 enhances Arginase-1 expression, which reduces LPS-induced mouse peritonitis by targeting JAK1/STAT6. AhR, Arg-1, NO, PMs
2020 Florfenicol induces oxidative stress and hepatocyte apoptosis in broilers via Nrf2 pathway. ALB, ALP, AST, CAT, FFC, HO-1, MDA, NQO-1, Nrf2, PLT, RBC, RGB, SOD, TP, WBC
2020 Genetic Polymorphisms of the Human Cytochrome P450 1A1 (CYP1A1) and Cervical Cancer Susceptibility among Northeast Thai Women. SCCA
2020 Human CYP1A1 inhibition by flavonoids. 3HF, 5HF, EROD, PAHs
2020 Human Cytochrome P450 1A1 Adapts Active Site for Atypical Nonplanar Substrate. ---
2020 In vitro and in vivo approaches for identifying the role of aryl hydrocarbon receptor in the development of nonalcoholic fatty liver disease. AhR, BaP, BMI, NAFLD, PPARalpha, SREBP-1c
2020 Serotonin Modulates AhR Activation by Interfering with CYP1A1-Mediated Clearance of AhR Ligands. AhR, EROD, FICZ, IECs, SERT, Trp
10  2019 A highly selective ratiometric fluorescent probe based on naphthalimide for detection and imaging of CYP1A1 in living cells and zebrafish. ---
11  2019 AhR regulates the expression of human cytochrome P450 1A1 (CYP1A1) by recruiting Sp1. AhR, Sp1, XRE
12  2019 Alpha-naphthoflavone attenuates non-alcoholic fatty liver disease in oleic acid-treated HepG2 hepatocytes and in high fat diet-fed mice. AhR, ANF, HFD, IR, NAFLD, OA, TNF-alpha
13  2019 Alteration of benzo(a)pyrene biotransformation by resveratrol in ApcMin/+ mouse model of colon carcinogenesis. BaP, GST, RVT
14  2019 Antagonizing Effects of Clematis apiifolia DC. Extract against Benzo[a]pyrene-Induced Damage to Human Keratinocytes. AhR, ARE, CAE, HO-1, ROS
15  2019 Anti-Colorectal Cancer Mechanisms of Formononetin Identified by Network Pharmacological Approach. ABCG2, ALS, CRC, CYP3A4, DAVID, EGFR, ERBB2, FN, HIT, MAPK, PPI, TNF, TP53
16  2019 Anti-tumor properties of methoxylated analogues of resveratrol in malignant MCF-7 but not in non-tumorigenic MCF-10A mammary epithelial cell lines. AhR, TMS, TMS
17  2019 Aromatic hydrocarbon receptor provides a link between smoking and rheumatoid arthritis in peripheral blood mononuclear cells. AHR, AHRR, CSE, PBMCs, RA, TCDD
18  2019 Association between polymorphisms in the CYP1A1, CYP2E1 and GSTM1 genes, and smoking, alcohol and upper digestive tract carcinomas in a high-incidence area of northern China. CIs, CYP2E1, EC, GAC, GCC, GSTM1, ORs, UDTC
19  2019 Association of CYP1A1 M2 (A2455G) Polymorphism with Susceptibility to Breast Cancer in Mazandaran Province, Northern Iran: A Case-control Study. SNPs
20  2019 Biochemical and molecular biomarkers in integument biopsies of free-ranging coastal bottlenose dolphins from southern Brazil. AhR, ARNT, GLMs, GPx, GR, GST, IL-1alpha, LES, MHC-II, MT2A, PLE, POPs, SOD
21  2019 CYP1A1 methylation mediates the effect of smoking and occupational polycyclic aromatic hydrocarbons co-exposure on oxidative DNA damage among Chinese coke-oven workers. OR, PAH
22  2019 CYP1A1, GSTT1, IL-6 and IL-8 transcription and IL-6 secretion on umbilical endothelial cells from hypertensive pregnant women: Preliminary results. GSTT1, HD, IL-6, PW
23  2019 Cytotoxicity of hexahelicene and its effect on the aryl hydrocarbon receptor pathway. AhR
24  2019 Expression of CYP and GST in human normal and colon tumor tissues. GSTP1
25  2019 Gene-gene-environment interactions of prenatal exposed to environmental tobacco smoke, CYP1A1 and GSTs polymorphisms on full-term low birth weight: relationship of maternal passive smoking, gene polymorphisms, and FT-LBW. ETS, FT-LBW, GSTs
26  2019 Highly sensitive fluorescent bioassay of 2,3,7,8-tetrachloro-dibenzo-p-dioxin based on abnormal expression of cytochrome P450 1A2 in human cells. 7-ER, CYP1A2, HBMN
27  2019 Human placental extract ameliorates cytokine and cytokine receptor signaling in the rat hippocampus upon Benzo[a]Pyrene exposure. HPE
28  2019 Hypopharyngeal cancer risk in Japanese: Genetic polymorphisms related to the metabolism of alcohol- and tobacco-associated carcinogens. ADH1B, ALDH2, GST, HC, OR
29  2019 Impact of CH223191-Induced Mitochondrial Dysfunction on Its Aryl Hydrocarbon Receptor Agonistic and Antagonistic Activities. AhR, BSO, FICZ, NAC, ROS
30  2019 Impact of crude oil and the dispersant Corexit™ EC9500A on capelin (Mallotus villosus) embryo development. CEWAF, WAF
31  2019 Inflammatory marker and aryl hydrocarbon receptor-dependent responses in human macrophages exposed to emissions from biodiesel fuels. AhR, CARB, COX, IL
32  2019 Liposome mediated-CYP1A1 gene silencing nanomedicine prepared using lipid film-coated proliposomes as a potential treatment strategy of lung cancer. PAHs
33  2019 Myclobutanil accumulation, transcriptional alteration, and tissue injury in lizards (Eremias argus) treated with myclobutanil enantiomers. ---
34  2019 Oroxylin A, a methylated metabolite of baicalein, exhibits a stronger inhibitory effect than baicalein on the CYP1B1-mediated carcinogenic estradiol metabolite formation. CYP1B1
35  2019 Primary endometrial 3D co-cultures: A comparison between human and rat endometrium. AhR, TCDD
36  2019 Staphylococcus epidermidis Activates Aryl Hydrocarbon Receptor Signaling in Human Keratinocytes: Implications for Cutaneous Defense. AhR
37  2019 T-2 toxin upregulates the expression of human cytochrome P450 1A1 (CYP1A1) by enhancing NRF1 and Sp1 interaction. AhR
38  2019 The role of phase I and II genetic polymorphisms, smoking, alcohol and cancer family history, in the risk of developing testicular cancer. GSTs, TCa, UGT
39  2019 [Non aromatic hydrocarbon receptor dependent regulatory mechanism of cytochrome P4501A1 and its role in infection and inflammation]. AhR
40  2018 27-Deoxyactein prevents 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced cellular damage in MC3T3-E1 osteoblastic cells. AhR, ALP, BSP, ERK, MMP, NF-kappaB, ROS, SOD, TCDD
41  2018 4-(3-Alkyl-2-oxoimidazolidin-1-yl)-N-phenylbenzenesulfonamides as new antimitotic prodrugs activated by cytochrome P450 1A1 in breast cancer cells. PAIB-SAs, PAIB-SOs
42  2018 Adiponectin attenuates kidney injury and fibrosis in deoxycorticosterone acetate-salt and angiotensin II-induced CKD mice. Ang II, ApN, CKD, DOCA, I3C, WT
43  2018 Aryl hydrocarbon receptor inhibits inflammation in DSS‑induced colitis via the MK2/p‑MK2/TTP pathway. AhR, DSS, IBD, LPS, TTP
44  2018 Bacterial mutagenicity of selected procarcinogens in the presence of recombinant human or rat cytochrome P4501A1. ---
45  2018 Biochemical responses of Gammarus pulex to malachite green solutions decolorized by Coriolus versicolor as a biosorbent under batch adsorption conditions optimized with response surface methodology. CAT, GPx, GST, MDA, MG, RSM, SOD
46  2018 Curcumin and its derivatives inhibit 2,3,7,8,-tetrachloro-dibenzo-p-dioxin-induced expression of drug metabolizing enzymes through aryl hydrocarbon receptor-mediated pathway. AhR, HO-1, NQO1, Nrf2, TCDD
47  2018 CYP1A1 Relieves Lipopolysaccharide-Induced Inflammatory Responses in Bovine Mammary Epithelial Cells. INEs
48  2018 Cytochrome P450 1A1 (CYP1A1) Catalyzes Lipid Peroxidation of Oleic Acid-Induced HepG2 Cells. BaP, NAFLD, OA
49  2018 Cytochrome P450 1A1 (CYP1A1) protects against nonalcoholic fatty liver disease caused by Western diet containing benzo[a]pyrene in mice. BaP, NAFLD
50  2018 Cytochrome P450 1A1 gene polymorphisms and cervical cancer risk: A systematic review and meta-analysis. CI, ORs
51  2018 Dietary L-Tryptophan Modulates the Structural and Functional Composition of the Intestinal Microbiome in Weaned Piglets. AhR, IL-8, SCFAs, TNF-alpha, Trp, ZO
52  2018 Effects of dietary crude oil exposure on molecular and physiological parameters related to lipid homeostasis in polar cod (Boreogadus saida). ---
53  2018 Furanoflavones pongapin and lanceolatin B blocks the cell cycle and induce senescence in CYP1A1-overexpressing breast cancer cells. PAHs
54  2018 Galangin, a dietary flavonol inhibits tumor initiation during experimental pulmonary tumorigenesis by modulating xenobiotic enzymes and antioxidant status. LPO
55  2018 GSH/GSSG redox couple plays central role in aryl hydrocarbon receptor-dependent modulation of cytochrome P450 1A1. AhR, BSO, FICZ, NAC
56  2018 Hyperoxia-mediated transcriptional activation of cytochrome P4501A1 (CYP1A1) and decreased susceptibility to oxygen-mediated lung injury in newborn mice. BPD, Luc, WT
57  2018 Identification and characterization of long non-coding RNAs in porcine granulosa cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin. AhR, DELs, lncRNAs, TCDD
58  2018 Modulations of TCDD-mediated induction of zebrafish cyp1a1 and the AHR pathway by administering Cd2+invivo. TCDD
59  2018 Renal toxicity through AhR, PXR, and Nrf2 signaling pathway activation of ochratoxin A-induced oxidative stress in kidney cells. AhR, KIM-1, Nrf2, OTA, PXR
60  2018 Serotonin is an endogenous regulator of intestinal CYP1A1 via AhR. AhR, ARNT, SERT
61  2018 Sp1, Instead of AhR, Regulates the Basal Transcription of Porcine CYP1A1 at the Proximal Promoter. XRE
62  2018 Structures of human cytochrome P450 1A1 with bergamottin and erlotinib reveal active-site modifications for binding of diverse ligands. ---
63  2018 The aryl hydrocarbon receptor-cytochrome P450 1A1 pathway controls lipid accumulation and enhances the permissiveness for hepatitis C virus assembly. AhR, HCV, LDs
64  2018 The impact of chemotherapeutic drugs on the CYP1A1-catalysed metabolism of the environmental carcinogen benzo[a]pyrene: Effects in human colorectal HCT116 TP53(+/+), TP53(+/-) and TP53(-/-) cells. BaP
65  2018 Transcriptional inhibition of TCDD-mediated induction of cytochrome P450 1A1 and alteration of protein expression in a zebrafish hepatic cell line following the administration of TCDD and Cd2. arnt2b, ZFL
66  2018 Urolithin A Is a Dietary Microbiota-Derived Human Aryl Hydrocarbon Receptor Antagonist. AhR, IL-6, PTGS2, TCDD
67  2017 Application of CRS-PCR-RFLP to identify CYP1A1 gene polymorphism. CRS-PCR
68  2017 Aryl hydrocarbon receptor signaling modifies Toll-like receptor-regulated responses in human dendritic cells. AhR, CDX2, DCs, FICZ, I3C, IL, KYN, moDCs, TCDD, TLR
69  2017 Association of prenatal passive smoking and metabolic gene polymorphisms with child growth from birth to 3years of age in the Hokkaido Birth Cohort Study on Environment and Children's Health. EPHX1, NAT2
70  2017 Biochemical characterization of variants of canine CYP1A1 using heterologous expression. EROD
71  2017 Biotransformation of Chrysin to Baicalein: Selective C6-Hydroxylation of 5,7-Dihydroxyflavone Using Whole Yeast Cells Stably Expressing Human CYP1A1 Enzyme. ---
72  2017 CYP1A1 Ile462Val Polymorphism Is Associated with Cervical Cancer Risk in Caucasians Not Asians: A Meta-Analysis. CNKI, ORs
73  2017 Cytochrome P450 1A1 (CYP1A1) Gene Polymorphisms and Susceptibility to Breast Cancer: a Meta-Analysis in the Chinese Population. CIs, ORs
74  2017 Echinocystic acid ameliorates hyperhomocysteinemia-induced vascular endothelial cell injury through regulating NF-kappaB and CYP1A1. EA, Hcy, Hhcy, MC, NC, NF, VC
75  2017 Effects of berberine on the secretion of cytokines and expression of genes involved in cell cycle regulation in THP-1 monocytic cell line. AhR, AML, BBR, CDK2, IL-1 beta, PMA
76  2017 Effects of human blood levels of two PAH mixtures on the AHR signalling activation pathway and CYP1A1 and COMT target genes in granulosa non-tumor and granulosa tumor cell lines. AhR, AHRR, ARNT, COMT, PAHs
77  2017 From the Cover: High Susceptibility of Lrig1 Sebaceous Stem Cells to TCDD in Mice. AhR, LRIG1, TCDD
78  2017 Gene variants of CYP1A1 and CYP2D6 and the risk of childhood acute lymphoblastic leukaemia; outcome of a case control study from Kashmir, India. ALL, ORs
79  2017 Gene-gene interaction between PPARG and CYP1A1 gene on coronary artery disease in the Chinese Han Population. CAD, PPAR-G, SNPs
80  2017 Involvement of the cytokine-IDO1-AhR loop in zinc oxide nanoparticle-induced acute pulmonary inflammation. AhR, IDO, KYN, NPs, ZnO NPs
81  2017 Mitochondrial activity and oxidative stress functions are influenced by the activation of AhR-induced CYP1A1 overexpression in cardiomyocytes. AhR, KD, PBMCs, ROS
82  2017 Modulation of Benzo[a]Pyrene Induced Anxiolytic-Like Behavior by Retinoic Acid in Zebrafish: Involvement of Oxidative Stress and Antioxidant Defense System. PGZ, RA
83  2017 Modulation of benzo[a]pyrene-DNA adduct formation by CYP1 inducer and inhibitor. AhR, BaP, BPDE, TCDD
84  2017 The detoxification responses, damage effects and bioaccumulation in the scallop Chlamys farreri exposed to single and mixtures of benzo[a]pyrene and chrysene. AhR, ARNT, BaP, CAT, Chr, EROD, GPx, GST, Hsp90, LPO, P-gp, PC, SOD, SULT, UGT
85  2017 The highly bioactive molecule and signal substance 6-formylindolo[3,2-b]carbazole (FICZ) plays bi-functional roles in cell growth and apoptosis in vitro. AhR, FICZ
86  2017 Tissue-specific bioconcentration and biotransformation of cypermethrin and chlorpyrifos in a native fish (Jenynsia multidentata) exposed to these insecticides singly and in mixtures. GST, P-gp
87  2016 AHR/CYP1A1 interplay triggers lymphatic barrier breaching in breast cancer spheroids by inducing 12(S)-HETE synthesis. AhR, LEC
88  2016 Antioxidant and antitumor efficacy of Luteolin, a dietary flavone on benzo(a)pyrene-induced experimental lung carcinogenesis. CAT, CEA, GPx, GR, GST, LPO, NF-kappaB, NSE, PCNA, SOD
89  2016 Aryl hydrocarbon receptor negatively regulates lipid synthesis and involves in cell differentiation of SZ95 sebocytes invitro. AhR, BaP, EMA, PPAR, TCDD
90  2016 Association of CYP1A1, GSTM1 and GSTT1 gene polymorphisms with risk of non-small cell lung cancer in Andhra Pradesh region of South India. GSTM1
91  2016 Association of oxidative stress gene polymorphisms with presbycusis. GST
92  2016 Associations between CYP1A1 rs1048943 A > G and rs4646903 T > C genetic variations and colorectal cancer risk: Proof from 26 case-control studies. CRC, PB
93  2016 Benzo(a)pyrene induces interleukin (IL)-6 production and reduces lipid synthesis in human SZ95 sebocytes via the aryl hydrocarbon receptor signaling pathway. AhR, BaP, IL
94  2016 Characterization of differences in substrate specificity among CYP1A1, CYP1A2 and CYP1B1: an integrated approach employing molecular docking and molecular dynamics simulations. ---
95  2016 Combination effect of cytochrome P450 1A1 gene polymorphisms on uterine leiomyoma: A case-control study. UL
96  2016 CYP1A1 mediates the suppression of major inflammatory cytokines in pulmonary alveolar macrophage (PAM) cell lines caused by Mycoplasma hyponeumoniae. PAM
97  2016 Cytochrome P450 1A1 gene polymorphisms and digestive tract cancer susceptibility: a meta-analysis. CIs, DTC, ORs
98  2016 Deleterious effects of incense smoke exposure on kidney function and architecture in male albino rats. BUN, IL-4, MDA, PAHs, TEM, TNF-alpha, VOCs
99  2016 Dietary Omega-3 Polyunsaturated Fatty Acids Prevent Vascular Dysfunction and Attenuate Cytochrome P4501A1 Expression by 2,3,7,8-Tetrachlorodibenzo-P-Dioxin. AA, AhR, TCDD, TP
100  2016 Effect of CYP1A1 gene polymorphism and psychological distress on seminal analysis parameters. HADS