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■ Abbreviation / Long Form : DXR / doxorubicin

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Abbreviation:   DXR  (>> Co-occurring Abbreviation)
Long Form:   doxorubicin
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No. Year Title Co-occurring Abbreviation
2020 Doxorubicin Inhibits Phosphatidylserine Decarboxylase and Modifies Mitochondrial Membrane Composition in HeLa Cells. PE, PS, PSD
2020 Levosimendan prevents doxorubicin-induced cardiotoxicity in time- and dose-dependent manner: implications for inotropy. BC, eNOS, L-NAME, LEVO, PLN
2019 Anti-Tumor Effect of Inhibition of DNA Damage Response Proteins, ATM and ATR, in Endometrial Cancer Cells. ATM-Chk2, ATR-Chk1, DDR
2019 Caffeic acid phenethyl ester potentiates gastric cancer cell sensitivity to doxorubicin and cisplatin by decreasing proteasome function. CAPE
2019 Chrysin enhances anticancer drug-induced toxicity mediated by the reduction of claudin-1 and 11 expression in a spheroid culture model of lung squamous cell carcinoma cells. CLDNs, PDK1, SCC
2019 Development of Long-Circulating and Fusogenic Liposomes Co-encapsulating Paclitaxel and Doxorubicin in Synergistic Ratio for the Treatment of Breast Cancer. CI, IC50, PTX
2019 Different sensitivities of senescent breast cancer cells to immune cell-mediated cytotoxicity. ---
2019 Increased myocardial 18F-FDG uptake as a marker of Doxorubicin-induced oxidative stress. H6PD, NB
2019 Investigation of the antitumor activity and toxicity of long-circulating and fusogenic liposomes co-encapsulating paclitaxel and doxorubicin in a murine breast cancer animal model. BC, PTX
10  2019 Isolation of senescent cells by iodixanol (OptiPrep) density gradient-based separation. HCC
11  2019 Liposomes targeted to MHC-restricted antigen improve drug delivery and antimelanoma response. MAGE-A1, TCR
12  2019 Modification of fliposomes with a polycation can enhance the control of pH-induced release. ---
13  2019 Short and Long-Term Effects of the Exposure of Breast Cancer Cell Lines to Different Ratios of Free or Co-Encapsulated Liposomal Paclitaxel and Doxorubicin. BC, PTX
14  2019 Silymarin Enriched Extract (Silybum marianum) Additive Effect on Doxorubicin-Mediated Cytotoxicity in PC-3 Prostate Cancer Cells. SEE
15  2019 Synergistic therapeutic effects of Vitis vinifera extract and Silymarin on experimentally induced cardiorenal injury: The pertinent role of Nrf2. ---
16  2019 Synergistically Enhanced Inhibitory Effects of Pullulan Nanoparticle-Mediated Co-Delivery of Lovastatin and Doxorubicin to Triple-Negative Breast Cancer Cells. DS, FTIR, LV, PLV, TNBC
17  2019 Ten-year follow-up results of perioperative chemotherapy with doxorubicin and ifosfamide for high-grade soft-tissue sarcoma of the extremities: Japan Clinical Oncology Group study JCOG0304. IFM, PFS, STS
18  2019 Therapeutic effect of valsartan against doxorubicin-induced renal toxicity in rats. BUN, GPx, MDA, NO, NOS, SCr, SD, SOD
19  2019 Therapeutic Effects of Liraglutide, Oxytocin and Granulocyte Colony-Stimulating Factor in Doxorubicin-Induced Cardiomyopathy Model: An Experimental Animal Study. i.p
20  2018 Asiatic Acid Ameliorates Doxorubicin-Induced Cardiac and Hepato-Renal Toxicities with Nrf2 Transcriptional Factor Activation in Rats. AA
21  2018 Chemoprotective effects of curcumin on doxorubicin-induced nephrotoxicity in wistar rats: by modulating inflammatory cytokines, apoptosis, oxidative stress and oxidative DNA damage. CMN
22  2018 Cocoplum (Chrysobalanus icaco L.) decreases doxorubicin-induced DNA damage and downregulates Gadd45a, Il-1beta, and Tnf-alpha in vivo. ---
23  2018 Complete genome sequence of Streptomyces peucetius ATCC 27952, the producer of anticancer anthracyclines and diverse secondary metabolites. DNR, NRPS
24  2018 Curcumin ameliorates doxorubicin-induced cardiotoxicity by abrogation of inflammation, apoptosis, oxidative DNA damage, and protein oxidation in rats. ---
25  2018 Decrease in paracellular permeability and chemosensitivity to doxorubicin by claudin-1 in spheroid culture models of human lung adenocarcinoma A549 cells. CLDN1, PI3K, ZO
26  2018 Disulfiram reduces metastatic osteosarcoma tumor burden in an immunocompetent Balb/c or-thotopic mouse model. DSF, Hi DSF, ICG, Lo DSF, OS
27  2018 Dose-dependent effects of frutalin on in vitro maturation and fertilization of pig oocytes. COCs, FTL, IVM
28  2018 Doxorubicin Expands in Vivo Secretion of Circulating Exosome in Mice. ---
29  2018 Doxorubicin-induced renal inflammation in rats: Protective role of Plantago major. MCP-1, P. major, TNF-alpha
30  2018 Effect of short- and medium-term toxicity of doxorubicin on spermatogenesis in adult Wistar rats. ---
31  2018 Effects of doxorubicin on sperm DNA methylation in mouse models of testicular toxicity. ---
32  2018 Effects of folic acid on the antiproliferative efficiency of doxorubicin, camptothecin and methyl methanesulfonate in MCF-7 cells by mRNA endpoints. CPT, FA, MMS
33  2018 Elevation of sensitivity to anticancer agents of human lung adenocarcinoma A549 cells by knockdown of claudin-2 expression in monolayer and spheroid culture models. CMFDA
34  2018 Enhanced doxorubicin production by Streptomyces peucetius using a combination of classical strain mutation and medium optimization. ARTP
35  2018 Ethanolic Extracts from Azadirachta indica Leaves Modulate Transcriptional Levels of Hormone Receptor Variant in Breast Cancer Cell Lines. BC, DCM, EA, EENL
36  2018 Genome-guided exploration of metabolic features of Streptomyces peucetius ATCC 27952: past, current, and prospect. BCGs, DNR, ETS, GE, GM, GT, MT, NRPS
37  2018 HPLC Method Development for Quantification of Doxorubicin in Cell Culture and Placental Perfusion Media. HPLC
38  2018 Increase in resistance to anticancer drugs involves occludin in spheroid culture model of lung adenocarcinoma A549 cells. OCLN, PI3K
39  2018 Melatonin improves cardiac and mitochondrial function during doxorubicin-induced cardiotoxicity: A possible role for peroxisome proliferator-activated receptor gamma coactivator 1-alpha and sirtuin activity? ---
40  2018 Necrosis of osteosarcoma cells induces the production and release of high-mobility group box 1 protein. HMGB1
41  2018 Reduction of doxorubicin-induced genotoxicity by Handroanthus impetiginosus in mouse bone marrow revealed by micronucleus assay. MNPCEs, NCE, NEU, PCE, THI
42  2018 Spheroid-based 3D cell cultures identify salinomycin as a promising drug for the treatment of chondrosarcoma. CS, SAL
43  2018 Sustained Delivery of Doxorubicin via Acetalated Dextran Scaffold Prevents Glioblastoma Recurrence after Surgical Resection. Ace-DEX, GBM, PLA
44  2018 <Editors' Choice> Effect of postoperative doxorubicin administration on ischemic wound healing. ---
45  2017 A Score-Based Approach to 18F-FDG PET Images as a Tool to Describe Metabolic Predictors of Myocardial Doxorubicin Susceptibility. ECG, SUV
46  2017 Cellular glycosylation affects Herceptin binding and sensitivity of breast cancer cells to doxorubicin and growth factors. ---
47  2017 Comparative plasma and tissue distribution of Sun Pharma's generic doxorubicin HCl liposome injection versus Caelyx (doxorubicin HCl liposome injection) in syngeneic fibrosarcoma-bearing BALB/c mice and Sprague-Dawley rats. HCl
48  2017 Comparison between Radionuclide Ventriculography and Echocardiography for Quantification of Left Ventricular Systolic Function in Rats Exposed to Doxorubicin. ECHO, LVSF, RV
49  2017 DnrI of Streptomyces peucetius binds to the resistance genes, drrAB and drrC but is activated by daunorubicin. DNR, SARP
50  2017 Doxorubicin-induced mitophagy contributes to drug resistance in cancer stem cells from HCT8 human colorectal cancer cells. CSCs
51  2017 Drug Loaded Gingival Mesenchymal Stromal Cells (GinPa-MSCs) Inhibit In Vitro Proliferation of Oral Squamous Cell Carcinoma. GCB, MSCs, PTX
52  2017 Electrosprayed Myocet-like Liposomes: An Alternative to Traditional Liposome Production. ---
53  2017 Fasting regulates EGR1 and protects from glucose- and dexamethasone-dependent sensitization to chemotherapy. AMPK, ANP, BNP, DEXA, Egr-1, GR, PKA, RAPA
54  2017 High pemetrexed sensitivity of docetaxel-resistant A549 cells is mediated by TP53 status and downregulated thymidylate synthase. DOC, GGH, NSCLC, PEM, TS, VCR
55  2017 Induction of Apoptosis in Human Oral Keratinocyte by Doxorubicin. ---
56  2017 Lipodox (generic doxorubicin hydrochloride liposome injection): in vivo efficacy and bioequivalence versus Caelyx (doxorubicin hydrochloride liposome injection) in human mammary carcinoma (MX-1) xenograft and syngeneic fibrosarcoma (WEHI 164) mouse models. CIs, HCl
57  2017 Modulatory effects of metformin on mutagenicity and epithelial tumor incidence in doxorubicin-treated Drosophila melanogaster. MET
58  2017 Novel 5-oxo-hexahydroquinoline derivatives: design, synthesis, in vitro P-glycoprotein-mediated multidrug resistance reversal profile and molecular dynamics simulation study. MDR, P-gp, Rh123
59  2017 Prevention of tumor seeding during needle biopsy by chemotherapeutic-releasing gelatin sticks. GDSs
60  2017 Protective effects of the exopolysaccharide Lasiodiplodan against DNA damage and inflammation induced by doxorubicin in rats: Cytogenetic and gene expression assays. LS, MN
61  2017 Short-term and long-term models of doxorubicin-induced cardiomyopathy in rats: A comparison of functional and histopathological changes. DCM, HF, i.p, LT, ST
62  2017 Therapeutic effects of protein kinase N3 small interfering RNA and doxorubicin combination therapy on liver and lung metastases. PKN3, siRNA
63  2016 A CD13 inhibitor, ubenimex, synergistically enhances the effects of anticancer drugs in hepatocellular carcinoma. CSCs, ROS, SOR
64  2016 Altered pH gradient at the plasma membrane of osteosarcoma cells is a key mechanism of drug resistance. OS, P-gp
65  2016 Amelioration of Doxorubicin-Induced Cardiac and Renal Toxicity by Oxycarotenoid Lutein and Its Mechanism of Action. ---
66  2016 Down-Regulation of AKT Signalling by Ursolic Acid Induces Intrinsic Apoptosis and Sensitization to Doxorubicin in Soft Tissue Sarcoma. UA
67  2016 Elevated cardiac 3-deoxyglucosone, a highly reactive intermediate in glycation reaction, in doxorubicin-induced cardiotoxicity in rats. 3-DG, cTnI, TBARS
68  2016 Enhancement of Cytotoxicity of Three Apoptosis-inducing Agents Against Human Oral Squamous Cell Carcinoma Cell Line by Benzoxazinotropone. OSCC, TS
69  2016 Fraction of Auxemma oncocalyx and Oncocalyxone A Affects the In Vitro Survival and Development of Caprine Preantral Follicles Enclosed in Ovarian Cortical Tissue. AgNOR, BMP-15, DMSO, onco A, PCNA, TUNEL
70  2016 In situ cultured preantral follicles is a useful model to evaluate the effect of anticancer drugs on caprine folliculogenesis. POF, PTX
71  2016 Influence of dose reduction of vincristine in R-CHOP on outcomes of diffuse large B cell lymphoma. ARDI, CPM, DI, DLBCL, DLT, RDI, VCR
72  2016 Mitochondrial nucleoid clusters protect newly synthesized mtDNA during Doxorubicin- and Ethidium Bromide-induced mitochondrial stress. EB, mtDNA, mtSSB
73  2016 Modulating effect of losartan potassium on the mutagenicity and recombinogenicity of doxorubicin in somatic cells of Drosophila melanogaster. SMART, ST and HB
74  2016 Modulating effect of simvastatin on the DNA damage induced by doxorubicin in somatic cells of Drosophila melanogaster. SMART, ST
75  2016 Modulatory Effect of Betulinic Acid on the Genotoxicity Induced by Different Mutagens in V79 Cells. BA, CPT, MMS
76  2016 Monitoring the effects of doxorubicin on 3D-spheroid tumor cells in real-time. ---
77  2016 Myostatin as a Marker for Doxorubicin Induced Cardiac Damage. ---
78  2016 Ozone Ameliorates Doxorubicine-Induced Skin Necrosis - results from an animal model. DMSO, GSH-Px, IL-1 beta, MDA, SOD, TNF-alpha
79  2016 Quantitative Structure-cytotoxicity Relationship of 3-Benzylidenechromanones. 5-FU, QSAR, TS
80  2015 Acridine Orange is an Effective Anti-Cancer Drug that Affects Mitochondrial Function in Osteosarcoma Cells. AO, MDR, OS
81  2015 Antimutagenicity and induction of antioxidant defense by flavonoid rich extract of Myrcia bella Cambess. in normal and tumor gastric cells. ---
82  2015 Assessment of the genotoxic/clastogenic potential of coumarin derivative 6,7-dihydroxycoumarin (aesculetin) in multiple mouse organs. ---
83  2015 Cardiac troponin-I, brain natriuretic peptide and endothelin-1 levels in a rat model of doxorubicin-induced cardiac injury. BNP, cTnI, ET-1, HDD, LDD
84  2015 Dexrazoxane abrogates acute doxorubicin toxicity in marmoset ovary. ---
85  2015 Dexrazoxane Diminishes Doxorubicin-Induced Acute Ovarian Damage and Preserves Ovarian Function and Fecundity in Mice. ---
86  2015 Dexrazoxane exacerbates doxorubicin-induced testicular toxicity. DEX
87  2015 Effects of vitamin D on kidney histology and trpv1 channels in doxorubicin-induced nephropathy. i.p, MDA, RT-PCR
88  2015 Genotoxic and Antigenotoxic Potential of Momordica charantia Linn (Cucurbitaceae) in the Wing Spot Test of Drosophila melanogaster. HB, ST
89  2015 Hydrogel Based 3-Dimensional (3D) System for Toxicity and High-Throughput (HTP) Analysis for Cultured Murine Ovarian Follicles. FA-IPN, HTP
90  2015 In vitro enhancement of doxorubicin genotoxic activities and interference with cell cycle delay by Plumbago indica root ethanolic extract in human lymphocytes. EEPIR, SCE
91  2015 In vivo evaluation of the genetic toxicity of Rubus niveus Thunb. (Rosaceae) extract and initial screening of its potential chemoprevention against doxorubicin-induced DNA damage. ---
92  2015 Interactions of chromatin context, binding site sequence content, and sequence evolution in stress-induced p53 occupancy and transactivation. REs, TE
93  2015 Investigation of factors affecting in vitro doxorubicin release from PEGylated liposomal doxorubicin for the development of in vitro release testing conditions. ---
94  2015 Mechanistic model and analysis of doxorubicin release from liposomal formulations. ---
95  2015 Modulation of gene expression and cell cycle by botryosphaeran, a (1→3)(1→6)-beta-d-glucan in human lymphocytes. ---
96  2015 Preclinical studies of pegylated- and non-pegylated liposomal forms of doxorubicin as radiosensitizer on orthotopic high-grade glioma xenografts. ---
97  2015 Recombinogenic activity of Pantoprazole() in somatic cells of Drosophila melanogaster. BH, HB, MH, PPIs, SMART, ST
98  2015 Synergistic Genotoxic Effects and Modulation of Cell Cycle by Ginger Ethanolic Extracts in Adjunct to Doxorubicin in Human Lymphocytes In Vitro. EEZOR, SCE
99  2015 The ALDH1⁺ subpopulation of the human NMFH-1 cell line exhibits cancer stem-like characteristics. ALDH1, CSCs, MFH
100  2015 The alpha2beta1 binding domain of chondroadherin inhibits breast cancer-induced bone metastases and impairs primary tumour growth: a preclinical study. CHAD