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■ Abbreviation / Long Form : Egr-1 / early growth response protein 1

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Total Number of Papers: 95
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Abbreviation:   Egr-1  (>> Co-occurring Abbreviation)
Long Form:   early growth response protein 1
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No. Year Title Co-occurring Abbreviation
2020 Donepezil Prevents ox-LDL-Induced Attachment of THP-1 Monocytes to Human Aortic Endothelial Cells (HAECs). HAECs, ICAM-1, IL-6, LOX-1, oxLDL, TF, TNF-alpha
2020 Loss of EGR-1 uncouples compensatory responses of pancreatic beta cells. ---
2020 Nuclear Factor Kappa B Signaling Complexes in Acute Inflammation. AP-1, CREB, IL-6, NF-kappaB, Nrf2, PGC-1alpha, PIR, RPS3, STAT3
2020 Soluble Klotho regulates bone differentiation by upregulating expression of the transcription factor EGR-1. sKl
2020 Transcription factor EGR-1 transactivates the MMP1 gene promoter in response to TNFalpha in HaCaT keratinocytes. AP-1, MMP-1, NF-kappaB, TNF-alpha
2019 Cathepsin L activated by mutant p53 and Egr-1 promotes ionizing radiation-induced EMT in human NSCLC. CTSL, EMT, IR, mutp53, NSCLC
2019 Involvement of the Akt-dependent CREB signaling pathway in hydrogen-peroxide-induced early growth response protein-1 expression in rat vascular smooth muscle cells 1. CREB, VSMCs
2019 Long noncoding RNA NONHSAG053901 promotes diabetic nephropathy via stimulating Egr-1/TGF-beta-mediated renal inflammation. DN, lncRNA, MCs, TGF-beta
2019 Oral crocetin administration suppressed refractive shift and axial elongation in a murine model of lens-induced myopia. ---
10  2019 Sustained Egr-1 Response via p38 MAP Kinase Signaling Modulates Early Immune Responses of Dendritic Cells Parasitized by Toxoplasma gondii. DCs
11  2018 Effects of the combination of As2O3 and AZT on proliferation inhibition and apoptosis induction of hepatoma HepG2 cells following silencing of Egr-1. AZT, CI
12  2018 Egr-1 Maintains NSC Proliferation and Its Overexpression Counteracts Cell Cycle Exit Triggered by the Withdrawal of Epidermal Growth Factor. NSCs, SVZ
13  2018 Honey bee foraging induces upregulation of early growth response protein 1, hormone receptor 38 and candidate downstream genes of the ecdysteroid signalling pathway. DopEcR, EcR, HR38
14  2018 Identification of target gene and prognostic evaluation for lung adenocarcinoma using gene expression meta-analysis, network analysis and neural network algorithms. AURKA, CDK1, DEGs, ES, HNF4A, LUAD, NSCLC, TFs
15  2018 MMP-12 activates protease-activated receptor-1, upregulates placenta growth factor, and leads to pulmonary emphysema. COPD, MMPs, NE, PAR-1, PGF
16  2017 ATF3 inhibits the inflammation induced by Mycoplasma pneumonia in vitro and in vivo. ATF3, MP
17  2017 cAMP attenuates angiotensin-II-induced Egr-1 expression via PKA-dependent signaling pathway in vascular smooth muscle cells. Ang II, CREB, FSK, ISO, VASP
18  2017 Expression and clinical significance of EGR-1 and PTEN in the pituitary tumors of elderly patients. PTEN
19  2017 Inhibition of dipeptidyl peptidase-4 ameliorates cardiac ischemia and systolic dysfunction by up-regulating the FGF-2/EGR-1 pathway. FGF-2
20  2017 Maturation, Behavioral Activation, and Connectivity of Adult-Born Medium Spiny Neurons in a Striatal Song Nucleus. MSNs
21  2017 Necrostatin-1 Protects Against D-Galactosamine and Lipopolysaccharide-Induced Hepatic Injury by Preventing TLR4 and RAGE Signaling. DAMP, FHF, HMGB1, IL, LPS, PRR, RAGE, RIP
22  2016 Angiopoietin-like protein 1 antagonizes MET receptor activity to repress sorafenib resistance and cancer stemness in hepatocellular carcinoma. ANGPTL1, EMT, ERK/AKT, HCC
23  2016 Discovery of an artificial peptide agonist to the fibroblast growth factor receptor 1c/betaKlotho complex from random peptide T7 phage display. FGF21, FGFR1c, PEG
24  2016 Early Growth Response Protein-1 Expression by Insulin-Like Growth Factor-1 Requires ROS-Dependent Activation of ERK1/2 and PKB Pathways in Vascular Smooth Muscle Cells. CVD, DPI, IGF-1, ROS, VSMC
25  2016 Enhanced expression of immediate-early genes in mouse hippocampus after trimethyltin treatment. Arc, CA, DG, IEGs, TMT
26  2016 Expression analysis of Egr-1 ortholog in metamorphic brain of honeybee (Apis mellifera L.): Possible evolutionary conservation of roles of Egr in eye development in vertebrates and insects. BrdU, IEGs
27  2016 Neural and neuroendocrine processing of a non-photic cue in an opportunistically breeding songbird. GnIH, GnRH
28  2016 NF-kappaB-dependent increase in tissue factor expression is responsible for hypoxic podocyte injury. CD2AP, HIF-1alpha, NF-kappaB, PDTC, siRNA, TF, TFPI
29  2016 PDGF induces SphK1 expression via Egr-1 to promote pulmonary artery smooth muscle cell proliferation. HPASMCs, PAH, PASMCs, PDGF, S1P, SphK1
30  2016 Src tyrosine kinase mediates endothelin-1-induced early growth response protein-1 expression via MAP kinase-dependent pathways in vascular smooth muscle cells. ERK, ET-1, JNK, MAPK, MEFs, nrPTK, PKB, VSMCs
31  2016 [Expression of Egr-1, Nab2 and Cav-1 and its relationship with scar hyperplasia]. Cav-1
32  2015 C2238/alphaANP modulates apolipoprotein E through Egr-1/miR199a in vascular smooth muscle cells in vitro. APOE, NPR-C, VSMCs
33  2015 Hydrogen gas inhalation protects against liver ischemia/reperfusion injury by activating the NF-kappaB signaling pathway. AST, Bcl-2, HO-1, I/R, IL, NF-kappaB, qPCR, TNF
34  2015 Id1 expression in endothelial cells of the colon is required for normal response to injury. CREB, Id
35  2015 Involvement of dopaminergic and cholinergic systems in social isolation-induced deficits in social affiliation and conditional fear memory in mice. GH, MPH, p-CaMKII, SI
36  2015 STAT3 and its phosphorylation are involved in HIV-1 Tat-induced transactivation of glial fibrillary acidic protein. GFAP, HIV-1, STAT3
37  2014 Activating transcription factor 3-mediated chemo-intervention with cancer chemokines in a noncanonical pathway under endoplasmic reticulum stress. ATF3, ER
38  2014 Angiogenesis in gastric mucosa: an important component of gastric erosion and ulcer healing and its impairment in aging. PTEN, VEGF
39  2014 Changes of T-lymphocyte subpopulation and differential expression pattern of the T-bet and GATA-3 genes in diffuse large B-cell lymphoma patients after chemotherapy. DLBCL, GATA-3, IFN, IL, PBMCs, TGF
40  2014 Effects of prenatal cocaine exposure on social development in mice. BDNF, mPFC, PCE, PCOC, PD, SI, USVs
41  2014 Egr-1 participates in abnormally high gdnf gene transcription mediated by histone hyperacetylation in glioma cells. gdnf
42  2014 Expression Pattern of Early Growth Response Gene 1 during Olive Flounder (Paralichthys olivaceus) Embryonic Development. dah, RT-PCR
43  2014 Expression Pattern of Early Growth Response Gene 1 during Olive Flounder (Paralichthys olivaceus) Embryonic Development. dah, RT-PCR
44  2014 Involvement of the early growth response protein 1 in vascular pathophysiology: an overview. ---
45  2014 Protein kinase C-induced early growth response protein-1 binding to SNAIL promoter in epithelial-mesenchymal transition of human embryonic stem cells. EMT, FGF, hES, hPS, PKC
46  2014 Ribonucleotide reductase M2B inhibits cell migration and spreading by early growth response protein 1-mediated phosphatase and tensin homolog/Akt1 pathway in hepatocellular carcinoma. EMT, HCC, PTEN, RR, shRNA
47  2014 [Comparison of the expression profiles of cell death factors in articular cartilage between Kashin-Beck disease and osteoarthritis]. KBD, PDCD5
48  2013 5-Hydroxytryptamine 1A and 2B serotonin receptors in neurite outgrowth: involvement of early growth response protein 1. 5-HT1A
49  2013 Connectivity maps for biosimilar drug discovery in venoms: the case of Gila monster venom and the anti-diabetes drug Byetta. ATF-3, CMap, GLP-1, RASD1
50  2013 Induction of Transcription Factor Early Growth Response Protein 1 during HSV-1 Infection Promotes Viral Replication in Corneal Cells. ChIP, IE
51  2013 Insulin-like growth-factor-1-induced PKB signaling and Egr-1 expression is inhibited by curcumin in A-10 vascular smooth muscle cells. Ang II, ET-1, GSK-3beta, IGF-1, IGF-1R, PKB, VSMC
52  2013 Mechanisms by which the orexigen NPY regulates anorexigenic alpha-MSH and TRH. alpha-MSH, ARC, NPY, PC2, POMC, PVN, TRH
53  2013 Novel regulatory action of ribosomal inactivation on epithelial Nod2-linked proinflammatory signals in two convergent ATF3-associated pathways. ATF3, Nod2
54  2012 Early growth response protein-1 promoter-mediated synergistic antitumor effect of hTERTC27 gene therapy and 5-Flurorouracil on nasopharyngeal carcinoma. 5-FU
55  2012 FH535 potentiation of cigarette smoke condensate cytotoxicity is associated with changes in beta-catenin and EGR-1 signaling. CSC, EMT
56  2012 Molecular mechanisms of early growth response protein-1 (EGR-1) expression by quercetin in INS-1 beta-cells. SRE, SRF
57  2012 Nutritional aspects of epigenetic inheritance. AP-1, FFA, NF-kappaB, PUFAs
58  2012 Resveratrol inhibits the release of soluble fms-like tyrosine kinase (sFlt-1) from human placenta. sFlt
59  2012 Transcriptional response to calcium-sensing receptor stimulation. AP-1, Elk-1
60  2011 A circadian clock entrained by melatonin is ticking in the rat fetal adrenal. StAR
61  2011 Egr-1 expression during neointimal development in flow-associated pulmonary hypertension. PAH
62  2010 Airway injury from initiating ventilation in preterm sheep. BALF, HSP70, MCP-1
63  2010 Early growth response protein-1 (Egr-1) is preferentially expressed in T helper type 2 (Th2) cells and is involved in acute transcription of the Th2 cytokine interleukin-4. IL-4, TCR
64  2010 EGR-1 activation by EGF inhibits MMP-9 expression and lymphoma growth. EGF, MMP
65  2010 Expression of early growth response protein 1 in vasopressin neurones of the rat anterior olfactory nucleus following social odour exposure. AON
66  2010 Identification of early growth response protein 1 (EGR-1) as a novel target for JUN-induced apoptosis in multiple myeloma. MM
67  2010 Regulatory effect of acetyl-l-carnitine on expression of lenticular antioxidant and apoptotic genes in selenite-induced cataract. ALCAR, COXI, GAPDH
68  2010 The role of thymidine phosphorylase in the induction of early growth response protein-1 and thrombospondin-1 by 5-fluorouracil in human cancer carcinoma cells. 5-FU, FdUMP, PD-ECGF, TP, TS, TSP-1
69  2009 Estradiol promotes pituitary cell proliferation and gonadotroph differentiation at different doses and with different mechanisms in chick embryo. ERs, LH, PCNA
70  2009 Induction of mPer1 expression by GnRH in pituitary gonadotrope cells involves EGR-1. GnRH, LHbeta
71  2007 Hyperbaric oxygen induces basic fibroblast growth factor and hepatocyte growth factor expression, and enhances blood perfusion and muscle regeneration in mouse ischemic hind limbs. bFGF, HBO, HGF, VEGF
72  2006 Involvement of Egr-1 in lens epithelial cell death induced by selenite. ---
73  2006 Sustained expression of early growth response protein-1 blocks angiogenesis and tumor growth. bFGF, VEGF
74  2006 The transcription factor Egr-1 is a regulator of the human TopBP1 gene. TopBP1
75  2005 Behavioral testing upregulates pCaMKII, BDNF, PSD-95 and egr-1 in hippocampus of FVB/N mice. BDNF, PSD-95, TrkB
76  2005 Essential interaction of Egr-1 at an islet-specific response element for basal and gastrin-dependent glucagon gene transactivation in pancreatic alpha-cells. CCK2
77  2005 Molecular and immunohistological characterization of human cartilage two years following autologous cell transplantation. SOX9
78  2004 Control of phosphatase and tensin homolog (PTEN) gene expression in normal and neoplastic thyroid cells. PTEN
79  2004 The cAMP signaling system regulates LHbeta gene expression: roles of early growth response protein-1, SP1 and steroidogenic factor-1. LHbeta, PKC, SF-1
80  2003 Extracellular ATP stimulates the early growth response protein 1 (Egr-1) via a protein kinase C-dependent pathway in the human osteoblastic HOBIT cell line. ---
81  2003 The colon mitosis-inhibitor pyroglutamyl-histidyl-glycine alters expression of immediate-early cancer-related genes in HT-29 cells. pEHG
82  2002 GnRH regulates early growth response protein 1 transcription through multiple promoter elements. SREs
83  2002 Interaction of early growth response protein 1 (Egr-1), specificity protein 1 (Sp1), and cyclic adenosine 3'5'-monophosphate response element binding protein (CREB) at a proximal response element is critical for gastrin-dependent activation of the chromogranin A promoter. CgA, CREB, CREB, MEK1, Sp1
84  2001 A single Pitx1 binding site is essential for activity of the LHbeta promoter in transgenic mice. SF-1
85  2001 Androgen suppression of GnRH-stimulated rat LHbeta gene transcription occurs through Sp1 sites in the distal GnRH-responsive promoter region. DHT, Sp1
86  2000 Differential expression of egr-1 in osteoarthritic compared to normal adult human articular cartilage. ---
87  2000 Induction of early growth response protein-1 gene expression in the rat ovary in response to an ovulatory dose of human chorionic gonadotropin. eCG
88  2000 Sp1, steroidogenic factor 1 (SF-1), and early growth response protein 1 (egr-1) binding sites form a tripartite gonadotropin-releasing hormone response element in the rat luteinizing hormone-beta gene promoter: an integral role for SF-1. SF-1
89  2000 The nuclear, 75 kDa form of early growth response protein-1/nerve growth factor-induced A protein is primarily restricted to LH beta-subunit-expressing cells in rat anterior pituitary. ---
90  1999 Cloning of a long HIV-1 readthrough transcript and detection of an increased level of early growth response protein-1 (Egr-1) mRNA in chronically infected U937 cells. ---
91  1999 Suppression of tumor necrosis factor (TNF-alpha) gene expression by prostaglandin E(2). Role Of early growth response protein-1 (Egr-1). ---
92  1998 Egr-1 and Sp1 interact functionally with the 5-lipoxygenase promoter and its naturally occurring mutants. 5-LO
93  1998 Steroidogenic factor-1 and early growth response protein 1 act through two composite DNA binding sites to regulate luteinizing hormone beta-subunit gene expression. GSE, LHbeta, SF-1
94  1996 Casein kinase II associates with Egr-1 and acts as a negative modulator of its DNA binding and transcription activities in NIH 3T3 cells. CKII
95  1995 Early growth response protein 1 (Egr-1): prototype of a zinc-finger family of transcription factors. ---