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■ Abbreviation / Long Form : FGFR3 / fibroblast growth factor receptor 3

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Total Number of Papers: 668
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Abbreviation:   FGFR3  (>> Co-occurring Abbreviation)
Long Form:   fibroblast growth factor receptor 3
 Abbreviation Variation
 Long Form Variation
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No. Year Title Co-occurring Abbreviation
2020 Clinical and Radiologic Evaluation of an Individual with Hypochondroplasia and a Novel FGFR3 Mutation. HCH
2020 Clinical characterisation of sensory neuropathy with anti-FGFR3 autoantibodies. DRG, SNs
2020 Clinical characteristics of fibroblast growth factor receptor 3 antibody-related polyneuropathy: a retrospective study. ---
2020 Cryptogenic small-fiber neuropathies: Serum autoantibody binding to trisulfated heparan disaccharide and fibroblast growth factor receptor-3. IgG, IgM, SFN, TS-HDS
2020 Diagnostic and Prognostic Potential of Biomarkers CYFRA 21.1, ERCC1, p53, FGFR3 and TATI in Bladder Cancers. ERCC1, TATI, TP53
2020 Distinct Molecular Landscape of Epstein-Barr Virus Associated Pulmonary Lymphoepithelioma-Like Carcinoma Revealed by Genomic Sequencing. EBV, LELC, NSCLC, PD-L1
2020 DNA and RNA sequencing identified a novel oncogene VPS35 in liver hepatocellular carcinoma. HBV, LIHC, VPS35
2020 Endocytosis, trafficking and exocytosis of intact full-length botulinum neurotoxin type a in cultured rat neurons. HC/A, LC/A
2020 Fgfr3 Is a Positive Regulator of Osteoblast Expansion and Differentiation During Zebrafish Skull Vault Development. ---
10  2020 Fgfr3 mutation disrupts chondrogenesis and bone ossification in zebrafish model mimicking CATSHL syndrome partially via enhanced Wnt/beta-catenin signaling. ---
11  2020 FGFR3 Mutation Status and FGFR3 Expression in a Large Bladder Cancer Cohort Treated by Radical Cystectomy: Implications for Anti-FGFR3 Treatment?†. BC, DSS
12  2020 Fibroblast growth factor receptor 3 activates a network of profibrotic signaling pathways to promote fibrosis in systemic sclerosis. CREB, SSc
13  2020 Fibroblast Growth Factor Receptor 3 Alteration Status is Associated with Differential Sensitivity to Platinum-based Chemotherapy in Locally Advanced and Metastatic Urothelial Carcinoma. FGFR3alt, FGFR3wt, MIBCs, mUCs, NAC, OS, PFS
14  2020 Fluoride regulates the expression of extracellular matrix HSPG and related signaling pathways FGFR3 and Ihh/PTHrP feedback loop during endochondral ossification. EXT1, GAGs, GPC6, HS, HSPG, Ihh, PTHrP, STAT1
15  2020 HSP90 overexpression potentiates the B-cell receptor and fibroblast growth factor receptor survival signals in chronic lymphocytic leukemia cells. BCR, BTK, CLL, PLC
16  2020 Hyperphosphatemia Secondary to the Selective Fibroblast Growth Factor Receptor 1-3 Inhibitor Infigratinib (BGJ398) Is Associated with Antitumor Efficacy in Fibroblast Growth Factor Receptor 3-altered Advanced/Metastatic Urothelial Carcinoma. CI, FGFR, mUC
17  2020 Interaction of FGF9 with FGFR3-IIIb/IIIc, a putative driver of growth and aggressive behaviour of hepatocellular carcinoma. HCC
18  2020 LncRNA KCNQ1OT1 accelerates fracture healing via modulating miR-701-3p/FGFR3 axis. lncRNA, miRNAs
19  2020 Macrocerebellum in Achondroplasia: A Further CNS Manifestation of FGFR3 Mutations? ---
20  2020 MiR-132/212 promotes the growth of precartilaginous stem cells (PCSCs) by regulating Ihh/PTHrP signaling pathway. Ihh, PCSCs, Ptch1, PTHrP
21  2020 New developments in the management of achondroplasia. FGF, MAPK, natriuretic peptide receptor B
22  2020 Novel therapeutic approaches for the treatment of achondroplasia. ---
23  2020 p.Ser348Cys mutation in FGFR3 gene leads to "Mild ACH /Severe HCH" phenotype. ACH, AN, HCH, TK1, TM
24  2020 Pharmacokinetics and safety after once and twice a day doses of meclizine hydrochloride administered to children with achondroplasia. ACH, PK
25  2020 Phosphorylation of the Human Papillomavirus E2 Protein at Tyrosine 138 Regulates Episomal Replication. CTM, PV
26  2020 Polymorphous low-grade neuroepithelial tumor of the young: case report and review focus on the radiological features and genetic alterations. BRAF, CT, MR, PLNTY
27  2020 Role of the N-Terminal Transmembrane Helix Contacts in the Activation of FGFR3. G380R, NMR, TM, WT
28  2020 Severe achondroplasia due to two de novo variants in the transmembrane domain of FGFR3 on the same allele: A case report. ACH
29  2020 Structure-based drug design of 1,3,5-triazine and pyrimidine derivatives as novel FGFR3 inhibitors with high selectivity over VEGFR2. SBDD, VEGFR2
30  2020 TERT Promoter Mutation as a Potential Predictive Biomarker in BCG-Treated Bladder Cancer Patients. BC, BCG, TERTp
31  2020 Urine cytology suspicious for urothelial carcinoma: Prospective follow-up of cases using cytology and urine biomarker-based ancillary techniques. AUCs, FISH, GEC, HG, TERT, UC
32  2020 Whole Exome Sequencing with Comprehensive Gene Set Analysis Identified a Biparental-Origin Homozygous c.509G>A Mutation in PPIB Gene Clustered in Two Taiwanese Families Exhibiting Fetal Skeletal Dysplasia during Prenatal Ultrasound. COL1A1, DTDST, OI IX, PPIB, SD, SOX9, trio-WES
33  2020 Zoledronate inhibits the differentiation potential of adipose-derived stem cells into osteoblasts in repairing jaw necrosis. ADSCs, CTSK, ZOL
34  2020 [Exploring the clinical genetic characteristics and height for age growth curve of 210 patients with achondroplasia in China]. ACH
35  2019 Acanthosis nigricans in a Chinese girl with FGFR3 K650 T mutation: a case report and literature review. AN
36  2019 Benzyl isothiocyanate suppresses IGF1R, FGFR3 and mTOR expression by upregulation of miR-99a-5p in human bladder cancer cells. BC, BITC, IGF1R, mTOR, qPCR, RT
37  2019 Clinical Characteristics and Prognosis of MAF Deletion in Chinese Patients With Multiple Myeloma. IgH, MM
38  2019 Clinical features and molecular genetic analysis of thanatophoric dysplasia type I in a neonate with a de novo c.2419 T > C (p. Ter807Arg) (X807R) mutation in FGFR3. TDI
39  2019 Construction and characterization of immunoliposomes targeting fibroblast growth factor receptor 3. scFv
40  2019 Deleting Suppressor of Cytokine Signaling-3 in chondrocytes reduces bone growth by disrupting mitogen-activated protein kinase signaling. FGF18, GP, MAPK, micro-CT, PZ, SOCS
41  2019 Detection of Known and Novel FGFR Fusions in Non-Small Cell Lung Cancer by Comprehensive Genomic Profiling. BAG4, FGFR, FGFR1, FGFR2, FGFR4, LZTFL1, MET
42  2019 Dog as a Model for Osteoarthritis: The FGF4 Retrogene Insertion May Matter. CD, COX-2, FGF4, NCD, OA
43  2019 Ensemble-Based Replica Exchange Alchemical Free Energy Methods: The Effect of Protein Mutations on Inhibitor Binding. TIES
44  2019 ETV5 links the FGFR3 and Hippo signalling pathways in bladder cancer. UC
45  2019 FGFR3 promotes the growth and malignancy of melanoma by influencing EMT and the phosphorylation of ERK, AKT, and EGFR. CMM, EGFR, EMT, ERK
46  2019 FGFR3S249C mutation promotes chemoresistance by activating Akt signaling in bladder cancer cells. BCa
47  2019 Human Articular Chondrocytes Retain Their Phenotype in Sustained Hypoxia While Normoxia Promotes Their Immunomodulatory Potential. ALK1, FC, MSCs
48  2019 Identification of a novel mutation of FGFR3 gene in a large Chinese pedigree with hypochondroplasia by next-generation sequencing: A case report and brief literature review. HCH, NGS
49  2019 Imbalanced development of anterior and posterior thorax is a causative factor triggering scoliosis. AIS, CT
50  2019 In vitro antitumor effects of FGFR and PI3K inhibitors on human papillomavirus positive and negative tonsillar and base of tongue cancer cell lines. PIK3CA
51  2019 Interaction between TP53 and XRCC1 increases susceptibility to cervical cancer development: a case control study. MAMA-PCR, SNP-SNP, TP53, XRCC1
52  2019 Mutation of chromatin regulators and focal hotspot alterations characterize human papillomavirus-positive oropharyngeal squamous cell carcinoma. CREBBP, CTCF, EP300, HNSCC, HPV, NSD1, OPSCC, PIK3CA
53  2019 Neurological Manifestations of Achondroplasia. ---
54  2019 Optimal non-invasive diagnosis of fetal achondroplasia combining ultrasonography with circulating cell-free fetal DNA analysis. cffDNA, HRM, NIPT
55  2019 Phosphorylation of a Conserved Tyrosine in the Papillomavirus E2 Protein Regulates Brd4 Binding and Viral Replication. aa, Brd4, CTD, HPVs, PV, WT
56  2019 Prenatal diagnosis of fetal skeletal dysplasia using targeted next-generation sequencing: an analysis of 30 cases. CHRNG, FLNB, SOX9, TP63
57  2019 Reducing the risk of misdiagnosis of indirect ELISA by normalizing serum-specific background noise: The example of detecting anti-FGFR3 autoantibodies. ELISA, SSBN
58  2019 The Effects of Fluvastatin on Indian Hedgehog Pathway in Endochondral Ossification. Ihh, PTHrP
59  2019 Transient Redirection of SVZ Stem Cells to Oligodendrogenesis by FGFR3 Activation Promotes Remyelination. OL, SVZ
60  2019 Tumor‑infiltrating M2macrophages driven by specific genomic alterations are associated with prognosis in bladder cancer. mi, MIBC
61  2018 A novel S269C mutation in fibroblast growth factor receptor 3 in a Japanese child with hypochondroplasia. HCH
62  2018 A phase III study of INCB054828 as adjuvant therapy in patients (pts) with high-risk urothelial carcinoma (UC) harboring fibroblast growth factor receptor 3 (FGFR3) genomic alterations. pts, UC
63  2018 A Survey of Molecular Heterogeneity in Hepatocellular Carcinoma. CSF1R, FLT3, HCC, PDGFRA, PTEN, Smo, TP53
64  2018 Characterization of metastatic urothelial carcinoma via comprehensive genomic profiling of circulating tumor DNA. ARID1A, ERBB2, GAs, mUC, NGS, PIK3CA, TP53
65  2018 Comprehensive molecular screening by next generation sequencing reveals a distinctive mutational profile of KIT/PDGFRA genes and novel genomic alterations: results from a 20-year cohort of patients with GIST from north-western Greece. GIST, PDGFRA, PIK3CA
66  2018 Constitutively-active FGFR3 disrupts primary cilium length and IFT20 trafficking in various chondrocyte models of achondroplasia. ACH, IFT, mTOR, PC, TD
67  2018 Familial acanthosis nigricans with the FGFR3 mutation: Differences of pigmentation between male and female patients. ---
68  2018 FGFR3 Antibodies in Neuropathy: What to Do With Them? ---
69  2018 FGFR3-TACC3 is an oncogenic fusion protein in respiratory epithelium. LSL-F3T3, NSCLC, TACC3
70  2018 Fibroblast growth factor receptor 3 (FGFR3) aberrations in muscle-invasive urothelial carcinoma. UC
71  2018 Fibroblast growth factor receptor 3-mediated reactivation of ERK signaling promotes head and neck squamous cancer cell insensitivity to MEK inhibition. HNSCC
72  2018 High CDKN2A/p16 and Low FGFR3 Expression Predict Progressive Potential of Stage pT1 Urothelial Bladder Carcinoma. CDKN2A, LR, PFS, UBC
73  2018 Homeostasis and Disorder of Musculoskeletal System.Diagnosis and Treatment of Congenital Musculoskeletal Diseases. TGF
74  2018 Hotspot Mutations Detectable by Next-generation Sequencing in Exhaled Breath Condensates from Patients with Lung Cancer. APC, DDR2, EBC, EGFR, ERBB4, FBXW7, FGFR1, KRAS, MET, NGS, PIK3CA, PTEN, RET, SMAD4, STK11, TP53
75  2018 Low-grade neuroepithelial tumor: Unusual presentation in an adult without history of seizures. ATRX, EMA, GFAP, IDH1, LGNT, MRI, OLIG2, PLNTY, WHO
76  2018 miR-24-3p/FGFR3 Signaling as a Novel Axis Is Involved in Epithelial-Mesenchymal Transition and Regulates Lung Adenocarcinoma Progression. ---
77  2018 Mutant FGFR3 associated with SADDAN disease causes cytoskeleton disorganization through PLCgamma1/Src-mediated paxillin hyperphosphorylation. ER, SADDAN, TDII
78  2018 Nicotine upregulates FGFR3 and RB1 expression and promotes non-small cell lung cancer cell proliferation and epithelial-to-mesenchymal transition via downregulation of miR-99b and miR-192. EMT, NSCLC, RB1
79  2018 Noninvasive prenatal test for FGFR3-related skeletal dysplasia based on next-generation sequencing and plasma cell-free DNA: Test performance analysis and feasibility exploration. ACH, gDNA, NGS, TDI
80  2018 Novel and Recurrent Mutations in the FGFR3 Gene and Double Heterozygosity Cases in a Cohort of Brazilian Patients with Skeletal Dysplasia. ACH, HCH, HRM
81  2018 Novel phenotype of achondroplasia due to biallelic FGFR3 pathogenic variants. ACH
82  2018 Overexpression of FGFR3 in HPV-positive Tonsillar and Base of Tongue Cancer Is Correlated to Outcome. CAST-PCR, DFS, IHC
83  2018 Papillomavirus E2 protein is regulated by specific fibroblast growth factor receptors. PV
84  2018 Pilot study of dovitinib in patients with von Hippel-Lindau disease. AE, ccRCC, FGF, HBs, SD, TKI, VHL
85  2018 Proteomic analyses of signalling complexes associated with receptor tyrosine kinase identify novel members of fibroblast growth factor receptor 3 interactome. RTKs
86  2018 Receptor Tyrosine Kinase Fusions and BRAF Kinase Fusions are Rare but Actionable Resistance Mechanisms to EGFR Tyrosine Kinase Inhibitors. ALK, NTRK1, RET, RTK, TKIs
87  2018 Skeletal Characterization of the Fgfr3 Mouse Model of Achondroplasia Using Micro-CT and MRI Volumetric Imaging. micro-CT, MRI, WT
88  2018 Suppression of FGFR3- and MYC-dependent oncogenesis by tubacin: association with HDAC6-dependent and independent activities. HDAC6
89  2018 Temporal Lobe Malformations in Achondroplasia: Expanding the Brain Imaging Phenotype Associated with FGFR3-Related Skeletal Dysplasias. ---
90  2018 Transforming growth factor-beta1 (TGF-beta1) induces mouse precartilaginous stem cell differentiation through TGFRII-CK1epsilon-beta-catenin signalling. CK1epsilon, GSK3beta, PSC, PSCs, TGF-beta1, TGFRII
91  2018 Two cases of seborrheic keratosis of the external ear canal: involvement of PIK3CA and FGFR3 genes. HPV, SK, UV
92  2017 Acanthosis nigricans in a Japanese boy with hypochondroplasia due to a K650T mutation in FGFR3. AN, HCH
93  2017 Achondroplasia and Biliary Atresia: A Rare Association and Review of Literature. ACH, BA, FGF21, FGF23
94  2017 Achondroplasia: Development, pathogenesis, and therapy. ACH, HCH, SADDAN, TD
95  2017 Activated FGFR3 promotes bone formation via accelerating endochondral ossification in mouse model of distraction osteogenesis. ACH, DO
96  2017 Analysis of papillary urothelial carcinomas of the bladder with grade heterogeneity: supportive evidence for an early role of CDKN2A deletions in the FGFR3 pathway. PLGUC
97  2017 Circulatory CNP Rescues Craniofacial Hypoplasia in Achondroplasia. CNP
98  2017 Clinical dosage of meclozine promotes longitudinal bone growth, bone volume, and trabecular bone quality in transgenic mice with achondroplasia. ACH, AUC
99  2017 Dephosphorylation is the mechanism of fibroblast growth factor inhibition of guanylyl cyclase-B. ---
100  2017 Exploring the FGFR3-related oncogenic mechanism in bladder cancer using bioinformatics strategy. DEGs, miRNAs, PPI, TFs