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■ Abbreviation / Long Form : FLG / filaggrin

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Total Number of Papers: 192
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Abbreviation:   FLG  (>> Co-occurring Abbreviation)
Long Form:   filaggrin
 Abbreviation Variation
 Long Form Variation
 Pair(Abbreviation/Long Form) Variation
No. Year Title Co-occurring Abbreviation
2019 Age-specific changes in the molecular phenotype of patients with moderate-to-severe atopic dermatitis. AD, LOR
2019 Dupilumab progressively improves systemic and cutaneous abnormalities in patients with atopic dermatitis. AD, LOR
2019 Filaggrin null mutations are associated with altered circulating Tregs in atopic dermatitis. AD, EASI
2019 Invitro anti-inflammatory and skin protective properties of Virgin coconut oil. AQP3, INV, RHE, VCO
2019 Refined Immunochemical Characterization in Healthy Dog Skin of the Epidermal Cornification Proteins, Filaggrin, and Corneodesmosin. CDSN, mAbs
2019 The atopic march and atopic multimorbidity: Many trajectories, many pathways. AD
2019 Transient epidermal barrier deficiency and lowered allergic threshold in filaggrin-hornerin (FlgHrnr-/- ) double-deficient mice. HRNR, NMFs
2018 Association of filaggrin gene mutations and childhood eczema and wheeze with phthalates and phosphorus flame retardants in house dust: The Hokkaido study on Environment and Children's Health. CIs, DINP, ORs, PFRs
2018 Enhanced Expression of Genes Related to Xenobiotic Metabolism in the Skin of Patients with Atopic Dermatitis but Not with Ichthyosis Vulgaris. AD
10  2018 Epidermal lipid composition, barrier integrity, and eczematous inflammation are associated with skin microbiome configuration. AD
11  2018 Epistasis between FLG and IL4R Genes on the Risk of Allergic Sensitization: Results from Two Population-Based Birth Cohort Studies. IL-4R, IOW, MAAS
12  2018 Evaluation of skin- or sweat-characteristic mRNAs for inferring the human origin of touched contact traces. CDSN, LCE1C
13  2018 Exacerbation of ichthyosis vulgaris phenotype by co-inheritance of STS and FLG mutations in a Chinese family with ichthyosis: a case report. STS, XLI
14  2018 Fibroblast and keratinocyte gene expression following exposure to extracts of neem plant (Azadirachta indica). AQP3, bFGF, CERS3, COL1A1, COX-2, ELOVL1, ELOVL4, FGF7, HAS1, HAS2, HYAL1, HYAL2, IL-1 alpha, ITGA6, KRT1, MMP1, TGF-beta, TGM1, VEGF
15  2018 Fibroblast and keratinocyte gene expression following exposure to the extracts of holy basil plant (Ocimum tenuiflorum), malabar nut plant (Justicia adhatoda), and emblic myrobalan plant (Phyllanthus emblica). AQP3, bFGF, CERS3, COL1A1, COX-2, ELOVL1, ELOVL4, FGF7, HAS1, HAS2, HYAL1, HYAL2, IL-1 alpha, ITGA6, KRT1, MMP1, TGF-beta, TGM1, VEGF
16  2018 Filaggrin and tight junction proteins are crucial for IL-13-mediated esophageal barrier dysfunction. ALI, EoE, HEECs, TEER, TJ
17  2018 Genome-wide association study and meta-analysis in multiple populations identifies new loci for peanut allergy and establishes C11orf30/EMSY as a genetic risk factor for food allergy. ANGPT4, CTNNA3, EXOC4, ITGA6, MMP12, PA, SKAP1, SNPs
18  2018 High Order Formation and Evolution of Hornerin in Primates. HRNR
19  2018 Individuals with filaggrin-related eczema and asthma have increased long-term medication and hospital admission costs. CI, IRR
20  2018 Mechanism for initiation of food allergy: Dependence on skin barrier mutations and environmental allergen costimulation. ---
21  2018 Patients with Atopic Dermatitis Colonized with Staphylococcus aureus Have a Distinct Phenotype and Endotype. AD, LDH, TEWL
22  2018 Peptide nucleic acid (PNA) probe-based analysis to detect filaggrin mutations in atopic dermatitis patients. AD, FMCA, PNA
23  2018 Peptidylarginine deiminase is involved in maintaining the cornified oral mucosa of rats. PAD
24  2018 Sensitive skin is highly frequent in extrinsic atopic dermatitis and correlates with disease severity markers but not necessarily with skin barrier impairment. AD, HS, LAST, LDH, TEWL, VAS
25  2018 T Cell Leukemia/Lymphoma 1A is essential for mouse epidermal keratinocytes proliferation promoted by insulin-like growth factor 1. B-CLL, CFE, ESC, IGF1, IVL, KCs, T-PLL
26  2018 The role of the OVOL1-OVOL2 axis in normal and diseased human skin. AD
27  2018 Tiled array-based sequencing identifies enrichment of loss-of-function variants in the highly homologous filaggrin gene in African-American children with severe atopic dermatitis. AA, AD, LOF
28  2018 Upregulation of FLG, LOR, and IVL Expression by Rhodiola crenulata Root Extract via Aryl Hydrocarbon Receptor: Differential Involvement of OVOL1. AhR, IVL, LOR, OVOL1, RCE
29  2018 [Study on the mutation of Filaggrin gene in nasal polyps]. PCR
30  2017 Adiponectin Upregulates Filaggrin Expression via SIRT1-Mediated Signaling in Human Normal Keratinocytes. ARNT
31  2017 Anti-allergic and Profilaggrin (ProFLG)-mRNA expression modulatory effects of sacran. AD, CBA, CS, DME, DNFB, PD, proFLG
32  2017 Antioxidant Artemisia princeps Extract Enhances the Expression of Filaggrin and Loricrin via the AHR/OVOL1 Pathway. AhR, APE, LOR, OVOL1
33  2017 Aryl hydrocarbon receptor activation restores filaggrin expression via OVOL1 in atopic dermatitis. AD, AhR, FICZ, NHEKs, OVOL1
34  2017 Atopic Dermatitis: Disease Background and Risk Factors. AD, ADHD, ASD
35  2017 Filaggrin and Periostin Expression Is Altered in Eosinophilic Esophagitis and Normalized With Treatment. EoE, GERD, POSTN
36  2017 Filaggrin loss-of-function mutations as a predictor for atopic eczema, allergic sensitization and eczema-associated asthma in Polish children population. OR
37  2017 Filaggrin mutations and Molluscum contagiosum skin infection in patients with atopic dermatitis. AD
38  2017 IL-1beta induces thymic stromal lymphopoietin and an atopic dermatitis-like phenotype in reconstructed healthy human epidermis. AD, RHE, TSLP
39  2017 Imiquimod-induced psoriasis-like inflammation in differentiated Human keratinocytes: Its evaluation using curcumin. IMQ, INV
40  2017 Increased filaggrin-metabolizing enzyme activity in atopic skin: a pilot study using a canine model of atopic dermatitis. ---
41  2017 Intragenic Copy Number Variation in the Filaggrin Gene in Ethiopian Patients with Atopic Dermatitis. AD
42  2017 Methyl-beta-cyclodextrin treatment combined to incubation with interleukin-4 reproduces major features of atopic dermatitis in a 3D-culture model. AD, HAS3, IL, LOR, MbetaCD, NELL2, RHE
43  2017 P38/ERK MAPK signaling pathways are involved in the regulation of filaggrin and involucrin by IL‑17. AD, ERK, IL, IVL, MAPK
44  2017 PAX6 regulates human corneal epithelium cell identity. ALDH3A1, ANGPTL7, Cas9, CECs, CLU, CRISPR, IVL, TKT
45  2017 Phytosphingosine enhances moisture level in human skin barrier through stimulation of the filaggrin biosynthesis and degradation leading to NMF formation. NMF, PHS
46  2017 Proteomic analysis of filaggrin deficiency identifies molecular signatures characteristic of atopic eczema. AE, KLK7, LSE, shNT
47  2017 Serum peptides as putative modulators of inflammation in psoriasis. AD, DMVECs, FPAdA, HC, PsA, PV
48  2017 SPINK5 is associated with early-onset and CHI3L1 with late-onset atopic dermatitis. ---
49  2017 Study protocol to investigate the environmental and genetic aetiology of atopic dermatitis: the Indonesian Prospective Study of Atopic Dermatitis in Infants (ISADI). AD, ISADI, LCPUFA
50  2017 TSLP is a direct trigger for T cell migration in filaggrin-deficient skin equivalents. AD, TSLP
51  2017 [The formation of skin barrier and defective barrier-associated skin diseases]. AD
52  2016 Acefylline activates filaggrin deimination by peptidylarginine deiminases in the upper epidermis. PADs
53  2016 Association between domestic water hardness, chlorine, and atopic dermatitis risk in early life: Apopulation-based cross-sectional study. AD, AOR
54  2016 Association of a Single Nucleotide Polymorphism in a Late Cornified Envelope-like Proline-rich 1 Gene (LELP1) with Atopic Dermatitis. HRNR, LELP1, LELP1
55  2016 Atopic Dermatitis Susceptibility Variants in Filaggrin Hitchhike Hornerin Selective Sweep. HRNR, LOF
56  2016 Clinical characteristics of Korean patients with filaggrin-related atopic dermatitis. AD
57  2016 Contact dermatitis in the construction industry: the role of filaggrin loss-of-function mutations. CD, CI, OR
58  2016 Distinct molecular signatures of mild extrinsic and intrinsic atopic dermatitis. AD
59  2016 Filaggrin and Skin Barrier Function. AD, SC
60  2016 Filaggrin-null mutations are associated with increased maturation markers on Langerhans cells. AD, APC, UCA
61  2016 FLG single nucleotide polymorphisms in chronic idiopathic urticaria. CIU, SNPs
62  2016 Genetic and epigenetic studies of atopic dermatitis. AD, GWAS
63  2016 Human melanomas and ovarian cancers overexpressing mechanical barrier molecule genes lack immune signatures and have increased patient mortality risk. TACSTD2
64  2016 Protective and therapeutic effects of fucoxanthin against sunburn caused by UV irradiation. Cdx1, FX, NAC, RA, ROS, UV
65  2016 Role of environmental exposures and filaggrin mutations on associations of ethnic origin with risk of childhood eczema. The Generation R Study. ---
66  2016 Skin Barrier Function Is Not Impaired and Kallikrein 7 Gene Polymorphism Is Frequently Observed in Korean X-linked Ichthyosis Patients Diagnosed by Fluorescence in Situ Hybridization and Array Comparative Genomic Hybridization. KLK7, SC, XLI
67  2016 T Helper 1 and T Helper 2 Cytokines Differentially Modulate Expression of Filaggrin and its Processing Proteases in Human Keratinocytes. AD, IFN-gamma, IL, LEKTI
68  2016 The tight junction gene Claudin-1 is associated with atopic dermatitis among Ethiopians. AD, WES
69  2016 Update on Epidemiology, Diagnosis, and Disease Course of Atopic Dermatitis. AD, TEWL
70  2015 Anatomical patterns of dermatitis in adult filaggrin mutation carriers. AD
71  2015 Explant cultures of atopic dermatitis biopsies maintain their epidermal characteristics in vitro. AD, Ex-HSE, HSEs
72  2015 Filaggrin deficiency promotes the dissemination of cutaneously inoculated vaccinia virus. AD, WT
73  2015 FLG P478S polymorphisms and environmental risk factors for the atopic march in Taiwanese children: a prospective cohort study. AD
74  2015 Genetic susceptibility for cow's milk allergy in Dutch children: the start of the allergic march? CMA, IL-2, SNP, TLR6
75  2015 Hypoxia-inducible factors regulate filaggrin expression and epidermal barrier function. HIFs
76  2015 Loss of sirtuin 1 (SIRT1) disrupts skin barrier integrity and sensitizes mice to epicutaneous allergen challenge. AD, SIRT1
77  2015 Loss-of-function mutations in the gene encoding filaggrin underlie a Japanese family with food-dependent exercise-induced anaphylaxis. FDEIA
78  2015 Skin barrier dysfunction measured by transepidermal water loss at 2 days and 2 months predates and predicts atopic dermatitis at 1 year. AD, TEWL
79  2015 The effect of phthalate exposure and filaggrin gene variants on atopic dermatitis. AD
80  2015 The hand eczema proteome: imbalance of epidermal barrier proteins. CHE, KLK
82  2014 Atopic dermatitis and disease severity are the main risk factors for food sensitization in exclusively breastfed infants. AD, CI, OR, SCORAD, TEWL
83  2014 Coherent somatic mutation in autoimmune disease. STR, TPO
84  2014 Epistasis between serine protease inhibitor Kazal-type 5 (SPINK5) and thymic stromal lymphopoietin (TSLP) genes contributes to childhood asthma. SPINK5, TSLP
85  2014 Evidence That Loss-of-Function Filaggrin Gene Mutations Evolved in Northern Europeans to Favor Intracutaneous Vitamin D3 Production. UVB, VD3
86  2014 Filaggrin deficiency leads to impaired lipid profile and altered acidification pathways in a 3D skin construct. PCA, sPLA2, UCA
87  2014 Filaggrin loss-of-function mutations are not a predisposing factor for atopic dermatitis in an Ishigaki Island under subtropical climate. AD, KIDS, SC
88  2014 Filaggrin single nucleotide polymorphisms in atopic dermatitis. AD
89  2014 Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis. AD
90  2014 Induction of a chloracne phenotype in an epidermal equivalent model by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is dependent on aryl hydrocarbon receptor activation and is not reproduced by aryl hydrocarbon receptor knock down. AhR, beta-NF, INV, ITE, NHEK, TCDD, TGM-1
91  2014 Mechanisms of abnormal lamellar body secretion and the dysfunctional skin barrier in patients with atopic dermatitis. AD, flg-2, hrn
92  2014 Mutations in the filaggrin gene and food allergy. AD
93  2014 Peanut allergy: effect of environmental peanut exposure in children with filaggrin loss-of-function mutations. CRD, SPT
94  2014 Possible new therapeutic strategy to regulate atopic dermatitis through upregulating filaggrin expression. AD, HaCaT
95  2014 Recombinant filaggrin is internalized and processed to correct filaggrin deficiency. AD, RHE
96  2014 Reduced filaggrin expression is accompanied by increased Staphylococcus aureus colonization of epidermal skin models. AMPs, FLG-KD, NEMs
97  2014 Severe skin inflammation and filaggrin mutation similarly alter the skin barrier in patients with atopic dermatitis. AD, SCORAD
98  2014 Staphylococcus aureus inhibits terminal differentiation of normal human keratinocytes by stimulating interleukin-6 secretion. IL, KRT10, LOR, NHKs, RHE, S. aureus, SC
99  2014 [Mouse models for spontaneous dermatitis due to impaired skin barrier formation]. ---
100  2013 Advances in allergic skin disease, anaphylaxis, and hypersensitivity reactions to foods, drugs, and insects in 2012. ---