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■ Abbreviation / Long Form : FOXO1 / forkhead box O1

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Total Number of Papers: 383
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Abbreviation:   FOXO1  (>> Co-occurring Abbreviation)
Long Form:   forkhead box O1
 Abbreviation Variation
 Long Form Variation
 Pair(Abbreviation/Long Form) Variation
No. Year Title Co-occurring Abbreviation
2020 Aging is associated with increased TRB3, ER stress, and hepatic glucose production in the liver of rats. BiP, CHOP, ER stress, G6Pase, p-PERK, PEPCK
2020 Bone marrow mesenchymal stem cells inhibit cardiac hypertrophy by enhancing FoxO1 transcription. AMPK, BMSCs, ISO
2020 Calcium relieves fluoride-induced bone damage through the PI3K/AKT pathway. ALP, Anxa5, Bax, Bcl-2, BIM, Ca, FAK, PDK1, PI3K, TGM2
2020 Chronic Timed Sleep Restriction Attenuates LepRb-Mediated Signaling Pathways and Circadian Clock Gene Expression in the Rat Hypothalamus. IRS, JAK2, PI3K, STAT3
2020 Circular RNA HIPK3 contributes to hyperglycemia and insulin homeostasis by sponging miR-192-5p and upregulating transcription factor forkhead box O1. circHIPK3, FSK/DEX, G6Pase, PEPCK, TG
2020 Depletion of hepatic forkhead box O1 does not affect cholelithiasis in male and female mice. ---
2020 Differential sensitivity of human islets from obese versus lean donors to chronic high glucose or palmitate. ---
2020 Doxorubicin induces cardiomyocyte apoptosis and atrophy through cyclin-dependent kinase 2-mediated activation of forkhead box O1. Bim, CDK2, DOX, MuRF1
2020 Effect of dapagliflozin, a sodium-glucose co-transporter-2 inhibitor, on gluconeogenesis in proximal renal tubules. CREB, G6Pase, PEPCK, PGC-1alpha, SGLT2
10  2020 Effect of Sleeve Gastrectomy on Glycometabolism via Forkhead Box O1 (FoxO1)/Lipocalin-2 (LCN2) Pathway. LCN2, MC4R, SG
11  2020 Expression of MALAT1 Promotes Trastuzumab Resistance in HER2 Overexpressing Breast Cancers. ChIP, MALAT1
12  2020 Fermented Feed Modulates Meat Quality and Promotes the Growth of Longissimus Thoracis of Late-Finishing Pigs. IR, LT, MAFbx, MyHC-I, MyoD
13  2020 FOXO1 inhibition prevents renal ischemia-reperfusion injury via cAMP-response element binding protein/PPAR-gamma coactivator-1alpha-mediated mitochondrial biogenesis. CREB, I/R, PGC-1alpha
14  2020 FoxO1 overexpression reduces Abeta production and tau phosphorylation in vitro. AD, APP, WT
15  2020 Garcinol Promotes Hepatic Gluconeogenesis by Inhibiting P300/CBP-Associated Factor in Late Pregnant Sows. ADFI, BW
16  2020 Genome‑wide analysis of DNA methylation and gene expression changes in an ovalbumin‑induced asthma mouse model. APP, DMRs, OVA, RUNX1, SP1
17  2020 High stretch cycling inhibits the morphological and biological decidual process in human endometrial stromal cells. 8-Br-cAMP, HESCs, IGFBP-1, MPA, PRL
18  2020 Imbalanced insulin substrate-1 and insulin substrate-2 signaling trigger hepatic steatosis in vitamin D deficient rats: 8-methoxypsoralen, a vitamin D receptor ligand with a promising anti-steatotic action. 8-MOP, IRS2, NAFLD, NASH, VDD
19  2020 Insulin‑receptor substrate 1 protects against injury inendothelial cell models of ox‑LDL‑induced atherosclerosis by inhibiting ER stress/oxidative stress‑mediated apoptosis and activating the Akt/FoxO1 signaling pathway. EC, G6PC, PCK1, ROS
20  2020 Investigating the role and mechanism of microRNA-196a in oral squamous cell carcinoma by targeting FOXO1. OSCC, RT-qPCR
21  2020 Long non-coding RNA plasmacytoma variant translocation 1 linked to hypoxia-induced cardiomyocyte injury of H9c2 cells by targeting miR-135a-5p/forkhead box O1 axis. lncRNAs, PVT1
22  2020 METTL14 aggravates endothelial inflammation and atherosclerosis by increasing FOXO1 N6-methyladeosine modifications. m6A, METTL14, RIP
23  2020 miR-421 promotes the viability of A549 lung cancer cells by targeting forkhead box O1. miR
24  2020 MiR-542-5p Inhibits Hyperglycemia and Hyperlipoidemia by Targeting FOXO1 in the Liver. FSK/DEX
25  2020 Overexpressed ITGA2 contributes to paclitaxel resistance by ovarian cancer cells through the activation of the AKT/FoxO1 pathway. ---
26  2020 Oxidized Oils and Oxidized Proteins Induce Apoptosis in Granulosa Cells by Increasing Oxidative Stress in Ovaries of Laying Hens. ADFI, ERK, FO, OO
27  2020 Polymerase independent repression of FoxO1 transcription by sequence-specific PARP1 binding to FoxO1 promoter. KO, PARP1, PARPis
28  2020 Prdx6 Plays a Main Role in the Crosstalk Between Aging and Metabolic Sarcopenia. DM, MuRF1, NCDs, Prdx6, SIRT1, T2DM
29  2020 Propofol inhibits proliferation and cisplatin resistance in ovarian cancer cells through regulating the microRNA‑374a/forkhead box O1 signaling axis. miR
30  2020 Reduced methylation of PP2Ac promotes ethanol-induced lipid accumulation through FOXO1 phosphorylation in vitro and in vivo. ALD, PP2A, PP2Ac
31  2020 Resistance exercise with anti-inflammatory foods attenuates skeletal muscle atrophy induced by chronic inflammation. CI, ERK, GAS, p70S6K, PG-PS, RE
32  2020 Selective inhibition of CBP/p300 HAT by A-485 results in suppression of lipogenesis and hepatic gluconeogenesis. CBP, G6PC, HFD, NCD, WAT
33  2020 The metabolic suppressor 3-iodothyronamine enhances lipolysis in 3T3-L1 adipocytes via activation of the adenosine monophosphate-activated protein kinase/forkhead box O1 signaling pathway. ACC, ATGL, CPT1, FFAs, MGL, pAMPK, TG
34  2020 Transmembrane protein 106C promotes the development of hepatocellular carcinoma. HCC, qRT-PCR, TMEM106C
35  2020 Trimetazidine improves hepatic lipogenesis and steatosis in non‑alcoholic fatty liver disease via AMPK‑ChREBP pathway. AMPK, ChREBP, HFD, NAFLD, TMZ
36  2020 Trimetazidine Inhibits Renal Tubular Epithelial Cells to Mesenchymal Transition in Diabetic Rats via Upregulation of Sirt1. AKI, CKD, DN, EMT, STZ, TMZ
37  2020 Uncovering the potential differentially expressed miRNAs as diagnostic biomarkers for hepatocellular carcinoma based on machine learning in The Cancer Genome Atlas database. EDNRB, FHL2, IL6ST, NR4A3, SFRP1
38  2020 Using ESTIMATE algorithm to establish an 8-mRNA signature prognosis prediction system and identify immunocyte infiltration-related genes in Pancreatic adenocarcinoma. CA9, CXCL9, DEGs, GIMAP7, PAAD
39  2020 [Advance in research of microRNA-21-5p regulate autophagy by targeting gene]. HALI, MAPK/ERK, miR-21-5p, TGF-beta
40  2019 A New Way for Beta Cell Neogenesis: Transdifferentiation from Alpha Cells Induced by Glucagon-Like Peptide 1. DM, GLP-1, MafA, PDX-1, PI3K, STZ
41  2019 Active pyruvate dehydrogenase and impaired gluconeogenesis in orthotopic hepatomas of rats. PC, PDH, PDK, TCA
42  2019 Altered FoxO1 and PPARgamma interaction in age-related ER stress-induced hepatic steatosis. ER
43  2019 Association of the polymorphisms in FOXO1 gene and diabetic nephropathy risk. DN, ORs, PCR-RFLP, SNPs
44  2019 Atrasentan alleviates high glucose-induced podocyte injury by the microRNA-21/forkhead box O1 axis. Atr, DN, HG, miR-21, miRNAs
45  2019 Camptothecin activates SIRT1 to promote lipid catabolism through AMPK/FoxO1/ATGL pathway in C2C12 myogenic cells. AMPK, ATGL, NAD, SIRT1
46  2019 Cellular stressors may alter islet hormone cell proportions by moderation of alternative splicing patterns. GCG, INS, SST, T1D, T2D
47  2019 Central administration of insulin and refeeding lead to the phosphorylation of AKT, but not FOXO1, in the hypothalamus of broiler chicks. i.c.v
48  2019 Chondrocytes Promote Vascularization in Fracture Healing Through a FOXO1-Dependent Mechanism. VEGF-A
49  2019 Circadian misalignment alters insulin sensitivity during the light phase and shifts glucose tolerance rhythms in female mice. GSIS, IPGTT, IPITT, ZT
50  2019 circRNA_0006393 promotes osteogenesis inglucocorticoid‑induced osteoporosis by sponging miR‑145‑5p and upregulating FOXO1. circRNAs, GIOP, miR
51  2019 Crucial lncRNAs associated with adipocyte differentiation from human adipose-derived stem cells based on co-expression and ceRNA network analyses. ASCs, ceRNA, DEGs, ESR1, lncRNAs, MIAT, PIK3R1, PPI, PTPRB
52  2019 Dietary Bile Acids Enhance Growth, and Alleviate Hepatic Fibrosis Induced by a High Starch Diet via AKT/FOXO1 and cAMP/AMPK/SREBP1 Pathway in Micropterus salmoides. BA, HSI, SREBP1, WGR
53  2019 Diverse inhibition of forkhead box O1 activity by linoleic acid isomers - potential role in lipid metabolism in HepG2 cells and livers of C57BL/6J mice. CLA, ORO
54  2019 Down-regulation of MicroRNA-592 in obesity contributes to hyperglycemia and insulin resistance. ---
55  2019 Effect of divergence in residual feed intake on expression of lipid metabolism-related genes in the liver of meat-type ducks1. ACC, ACOX1, ADFI, CPT1A, FAS, FCR, HRFI, LRFI, PPARgamma, RFI, SIRT1, SREBP-1c
56  2019 Effect of microRNA-370 on coronary atherosclerosis and its underlying mechanism. miRs
57  2019 Eriodictyol inhibits survival and inflammatory responses and promotes apoptosis in rheumatoid arthritis fibroblast-like synoviocytes through AKT/FOXO1 signaling. Akt, IL-6, RA-FLS
58  2019 Forced FoxO1:S249V expression suppressed glioma cell proliferation through G2/M cell cycle arrests and increased apoptosis. CDK
59  2019 Forkhead box O1 (FOXO1) controls the migratory response of Toll-like receptor (TLR3)-stimulated human mesenchymal stromal cells. hMSCs, MSCs, TLR3
60  2019 Forkhead box O1 as an indicator of prognosis is inactivated in urothelial carcinoma of the upper urinary tract. CC, p-FOXO1, UUT-UC
61  2019 FoxO1 controls the expansion of pre-B cells by regulating the expression of interleukin 7 receptor alpha chain and its signal pathway. IL-7Ralpha
62  2019 FOXO1 functions in the regulation of nicotinamide phosphoribosyltransferase (Nampt) expression. PI3K
63  2019 FoxO1 is a critical regulator of hepatocyte lipid deposition in chronic stress mice. NAFLD
64  2019 FoxO1-mediated inhibition of STAT1 alleviates tubulointerstitial fibrosis and tubule apoptosis in diabetic kidney disease. 3aFoxO1-KI, DKD, EMT, FoxO1-KD, TIF
65  2019 FXR activation alleviates tacrolimus-induced post-transplant diabetes mellitus by regulating renal gluconeogenesis and glucose uptake. FXR, GLUT2, PEPCK, PGC1alpha, PTDM
66  2019 Gegen Qinlian Decoction Ameliorates Hepatic Insulin Resistance by Silent Information Regulator1 (SIRT1)-Dependent Deacetylation of Forkhead Box O1 (FOXO1). GGQLD, HFD, IR, SIRT1
67  2019 Genetic variants in Forkhead box O1 associated with predisposition to sepsis in a Chinese Han population. SNPs
68  2019 Geniposide Improves Glucose Homeostasis via Regulating FoxO1/PDK4 in Skeletal Muscle. PDK4
69  2019 Glucose regulates the histone acetylation of gene promoters in decidualizing stromal cells. ESCs, H3K27ac, IGFBP-1, PRL
70  2019 Glutathione prevents chronic oscillating glucose intake-induced beta-cell dedifferentiation and failure. LOsG, ROS
71  2019 HBx-K130M/V131I Promotes Liver Cancer in Transgenic Mice via AKT/FOXO1 Signaling Pathway and Arachidonic Acid Metabolism. AA, FAH, HBV, HBx, HCC, SB, Trp53, WT
72  2019 High hydrostatic pressure induces apoptosis of retinal ganglion cells via regulation of the NGF signalling pathway. ASK1, CREB, HP, NGF, RGC
73  2019 Investigation of the clinical significance and molecular mechanism of miR-21-5p in hepatocellular carcinoma: A systematic review based on 24 studies and bioinformatics investigation. AUC, ESR1, GEO, GO, HCC, KEGG, miR-21-5p, PPI
74  2019 LIPUS promotes FOXO1 accumulation by downregulating miR-182 to enhance osteogenic differentiation in hPDLCs. ALP, hPDLCs, LIPUS
75  2019 LncRNA MEG3 accelerates apoptosis of hypoxic myocardial cells via FoxO1 signaling pathway. ATP, CCK-8, lncRNA, MEG3, qRT-PCR, TUNEL
76  2019 Metformin Protects the Heart Against Hypertrophic and Apoptotic Remodeling After Myocardial Infarction. BNP, I/R
77  2019 Micro-RNA-27a/b negatively regulates hepatic gluconeogenesis by targeting FOXO1. miRNAs
78  2019 MicroRNA Let-7f-1-3p attenuates smoke-induced apoptosis in bronchial and alveolar epithelial cells in vitro by targeting FOXO1. Bcl-2, FasL, HPAEpiC, HSAEC, miRNA, TRAIL
79  2019 MicroRNA-21-5p targeting PDCD4 suppresses apoptosis via regulating the PI3K/AKT/FOXO1 signaling pathway in tongue squamous cell carcinoma. miRNA, TSCC
80  2019 MicroRNA-223 is essential for maintaining functional beta-cell mass during diabetes through inhibiting both FOXO1 and SOX6 pathways. KO, miR-223, NKX6.1, PDX-1, SOX6, TNF-alpha, UCN3
81  2019 miR-135b Delivered by Gastric Tumor Exosomes Inhibits FOXO1 Expression in Endothelial Cells and Promotes Angiogenesis. GC, miR-135b, miRNAs
82  2019 miR-216a-5p promotes mesangial cell proliferation by targeting FoxO1 in diabetic nephropathy. CCK-8, CDK4, DN, HMC, miRNAs, PI, qRT-PCR, WB
83  2019 MiR-223-3p promotes the growth and invasion of neuroblastoma cell via targeting FOXO1. CCK-8, miRNAs, NB
84  2019 Molecular mechanisms of FOXO1 in adipocyte differentiation. ---
85  2019 Oleic acid increases the transcriptional activity of FoxO1 by promoting its nuclear translocation and beta-catenin binding in pancreatic beta-cells. SCD1
86  2019 Overexpression of Hes1 is involved in sensitization of K562 cells to Imatinib. CML, Hes1, TKI
87  2019 Oxaliplatin reverses the GLP-1R-mediated promotion of intrahepatic cholangiocarcinoma by altering FoxO1 signaling. GLP-1R, ICC
88  2019 Phosphorylation of Forkhead Protein FoxO1 at S253 Regulates Glucose Homeostasis in Mice. HGP
89  2019 Propofol Alleviates DNA Damage Induced by Oxygen Glucose Deprivation and Reperfusion via FoxO1 Nuclear Translocation in H9c2 Cells. AMPK, I/R, OGD/R, ROS
90  2019 Quxie Capsule Inhibits Colon Tumor Growth Partially Through Foxo1-Mediated Apoptosis and Immune Modulation. QX
91  2019 Resveratrol Promotes Diabetic Wound Healing via SIRT1-FOXO1-c-Myc Signaling Pathway-Mediated Angiogenesis. HUVECs, RES, SIRT1, TUNEL
92  2019 Salidroside protects against ox-LDL-induced endothelial injury by enhancing autophagy mediated by SIRT1-FoxO1 pathway. CCK-8, HUVECs, LDH, MDA, NAM, oxLDL, qRT-PCR, Sal, SOD
93  2019 Sirtuin 3 suppresses the formation of renal calcium oxalate crystals through promoting M2 polarization of macrophages. KS, SIRT3, TUNEL
94  2019 Targeting Wnt/EZH2/microRNA-708 signaling pathway inhibits neuroendocrine differentiation in prostate cancer. CDK1, EZH2, NE, NEPC, PC, TCF4
95  2019 Trichostatin A activates FOXO1 and induces autophagy in osteosarcoma. HDACIs, mTOR, siRNA, TSA
96  2019 Understanding the perspectives of forkhead transcription factors in delayed wound healing. FOXO
97  2019 Up-regulated ADP-Ribosylation factor 3 promotes breast cancer cell proliferation through the participation of FOXO1. ARF3
98  2019 Vitamin B5 inhibit RANKL induced osteoclastogenesis and ovariectomy induced osteoporosis by scavenging ROS generation. FoxO2, Nrf2, PI3K-AKT, pOCs, TRAP
99  2019 Zbtb7c is a critical gluconeogenic transcription factor that induces glucose-6-phosphatase and phosphoenylpyruvate carboxykinase 1 genes expression during mice fasting. G6PC, HDAC3, IREs, PCK1
100  2018 A novel mouse model of testicular granulosa cell tumors. AMHR2, FOXL2, GrCTs, H and E, INHA, TGFB, TGFBR1