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[Related PubMed/MEDLINE]
Total Number of Papers: 239
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| No. |
Year |
Title |
Co-occurring Abbreviation |
| 1 |
2020 |
AKT2 regulates endothelial-mediated coagulation homeostasis and promotes intrathrombotic recanalization and thrombus resolution in a mouse model of venous thrombosis. |
IVC, TF, TM, VTE, WT |
| 2 |
2020 |
Angiotensin II-upregulated MAP kinase phosphatase-3 modulates FOXO1 and p21 in adrenocortical H295R cells. |
Ang II, MAPK, MKP |
| 3 |
2020 |
Caffeine Upregulates Hepatic Sex Hormone-Binding Globulin Production by Increasing Adiponectin Through AKT/FOXO1 Pathway in White Adipose Tissue. |
AKT, SHBG |
| 4 |
2020 |
Comparative Analyses of mTOR/Akt and Muscle Atrophy-Related Signaling in Aged Respiratory and Gastrocnemius Muscles. |
--- |
| 5 |
2020 |
Epigallocatechin-3-Gallate (EGCG)-Inducible SMILE Inhibits STAT3-Mediated Hepcidin Gene Expression. |
EGCG, IL-6, SMILE, STAT3 |
| 6 |
2020 |
Fluoxetine regulates glucose and lipid metabolism via the PI3K‑AKT signaling pathway in diabetic rats. |
G6PC, PEPCK, STZ |
| 7 |
2020 |
FOXO1 contributes to diabetic cardiomyopathy via inducing imbalanced oxidative metabolism in type 1 diabetes. |
--- |
| 8 |
2020 |
FOXO1 promotes tumor progression by increased M2 macrophage infiltration in esophageal squamous cell carcinoma. |
ChIP, CSF-1, ESCC, qRT-PCR, TME |
| 9 |
2020 |
FOXO1 regulates developmental lymphangiogenesis by upregulating CXCR4 in the mouse-tail dermis. |
CXCL12, CXCR4, LECs |
| 10 |
2020 |
FOXO1 suppresses PGC-1beta gene expression in skeletal muscles. |
PGC-1beta |
| 11 |
2020 |
Genomic Binding Patterns of Forkhead Box Protein O1 Reveal Its Unique Role in Cardiac Hypertrophy. |
Pol II |
| 12 |
2020 |
GLP-1/GLP-1R Signaling Regulates Ovarian PCOS-Associated Granulosa Cells Proliferation and Antiapoptosis by Modification of Forkhead Box Protein O1 Phosphorylation Sites. |
GCs, PCOS |
| 13 |
2020 |
Hyperoside exhibits anticancer activity in non‑small cell lung cancer cells with T790M mutations by upregulating FoxO1 via CCAT1. |
CCAT1, EGFR, lncRNA, NSCLC |
| 14 |
2020 |
Knockdown of SGK1 alleviates the IL-1beta-induced chondrocyte anabolic and catabolic imbalance by activating FoxO1-mediated autophagy in human chondrocytes. |
IL-1beta, OA, SGK1 |
| 15 |
2020 |
Lignan from Alnus japonica Inhibits Adipocyte Differentiation via Cell Cycle and FOXO1 Regulation. |
--- |
| 16 |
2020 |
LncRNA GUSBP5-AS promotes EPC migration and angiogenesis and deep vein thrombosis resolution by regulating FGF2 and MMP2/9 through the miR-223-3p/FOXO1/Akt pathway. |
DVT, EPCs, FGF-2, lncRNAs |
| 17 |
2020 |
Luteolin-loading of Her-2-poly (lactic-co-glycolic acid) nanoparticles and proliferative inhibition of gastric cancer cells via targeted regulation of forkhead box protein O1. |
Her-2-NPs, NPs |
| 18 |
2020 |
Matrix Metalloproteinase-11 Promotes Early Mouse Mammary Gland Tumor Growth through Metabolic Reprogramming and Increased IGF1/AKT/FoxO1 Signaling Pathway, Enhanced ER Stress and Alteration in Mitochondrial UPR. |
ECM, HR-MAS, IGF-1, MMP11, MMTV, PyMT |
| 19 |
2020 |
MSC-Secreted Exosomal H19 Promotes Trophoblast Cell Invasion and Migration by Downregulating let-7b and Upregulating FOXO1. |
Akt, MSCs, PE |
| 20 |
2020 |
Multi-omics analysis identifies FoxO1 as a regulator of macrophage function through metabolic reprogramming. |
--- |
| 21 |
2020 |
N1-Methylnicotinamide Improves Hepatic Insulin Sensitivity via Activation of SIRT1 and Inhibition of FOXO1 Acetylation. |
MNAM, PA, SIRT1, T2DM |
| 22 |
2020 |
PDK4-Deficiency Reprograms Intrahepatic Glucose and Lipid Metabolism to Facilitate Liver Regeneration in Mice. |
AMPK, PDK4 |
| 23 |
2020 |
Red Pepper (Capsicum annuum L.) Seed Extract Improves Glycemic Control by Inhibiting Hepatic Gluconeogenesis via Phosphorylation of FOXO1 and AMPK in Obese Diabetic db/db Mice. |
AMPK, G6Pase, IL-6, ObD, PEPCK, RPSE, TNF-alpha |
| 24 |
2020 |
Resveratrol improves left ventricular remodeling in chronic kidney disease via Sirt1-mediated regulation of FoxO1 activity and MnSOD expression. |
CKD, MnSOD, RSV, SIRT1 |
| 25 |
2020 |
Role and mechanism of PI3K/AKT/FoxO1/PDX-1 signaling pathway in functional changes of pancreatic islets in rats after severe burns. |
ELISA, PDX-1, PI3K, TBSA, TEM |
| 26 |
2020 |
Statins induce skeletal muscle atrophy via GGPP depletion-dependent myostatin overexpression in skeletal muscle and brown adipose tissue. |
BAT, GGPP, IRF4 |
| 27 |
2020 |
Supplementary Oral Anamorelin Mitigates Anorexia and Skeletal Muscle Atrophy Induced by Gemcitabine Plus Cisplatin Systemic Chemotherapy in a Mouse Model. |
5-ALA, GC |
| 28 |
2020 |
Targeting Histone Deacetylase 6 Reprograms Interleukin-17-Producing Helper T Cell Pathogenicity and Facilitates Immunotherapies for Hepatocellular Carcinoma. |
HCC, HDAC6, IL-17, RORgammat |
| 29 |
2020 |
Targeting the PLK1-FOXO1 pathway as a novel therapeutic approach for treating advanced prostate cancer. |
PCa, Plk1 |
| 30 |
2020 |
The cleft palate candidate gene BAG6 supports FoxO1 acetylation to promote FasL-mediated apoptosis during palate fusion. |
BAG6, FasL, MEE, WES |
| 31 |
2020 |
The role and molecular mechanism of FoxO1 in mediating cardiac hypertrophy. |
--- |
| 32 |
2020 |
Up-regulation of FoxO1 contributes to adverse vascular remodelling in type 1 diabetic rats. |
STZ, T1DM |
| 33 |
2019 |
AKT as a Therapeutic Target for Cancer. |
AKT, GSK3beta, PDK |
| 34 |
2019 |
Alcohol dysregulates miR-148a in hepatocytes through FoxO1, facilitating pyroptosis via TXNIP overexpression. |
AH, ALD, miRNAs, TXNIP |
| 35 |
2019 |
AMPK and AKT protein kinases hierarchically phosphorylate the N-terminus of the FOXO1 transcription factor, modulating interactions with 14-3-3 proteins. |
AMPK |
| 36 |
2019 |
AMPK/FOXO1 signaling pathway is indispensable in visfatin-regulated myosin heavy chain expression in C2C12 myotubes. |
AMP, MHC |
| 37 |
2019 |
Aspalathin-Enriched Green Rooibos Extract Reduces Hepatic Insulin Resistance by Modulating PI3K/AKT and AMPK Pathways. |
AMPK, CPT1, GRE, INSR, IRS-1 and IRS-2, OBIR |
| 38 |
2019 |
Baicalin ameliorates neuroinflammation-induced depressive-like behavior through inhibition of toll-like receptor 4 expression via the PI3K/AKT/FoxO1 pathway. |
CUMS, IL-1beta, IL-6, LPS, PI3K, TLR4, TNF-alpha |
| 39 |
2019 |
Biochemical and molecular evidence on the role of vaspin in early detection of the insulin resistance in a rat model of high-fat diet and use of diazinon. |
ChE, DZN, FBG, HFD, HOMA-IR, OGTT, PTEN, ROS, TNF-alpha |
| 40 |
2019 |
Combination of Soy Protein, Amylopectin, and Chromium Stimulates Muscle Protein Synthesis by Regulation of Ubiquitin-Proteasome Proteolysis Pathway after Exercise. |
FOXO3, FSR, IGF-1, MAFbx, SAC |
| 41 |
2019 |
Decreased PKG transcription mediated by PI3K/Akt/FoxO1 pathway is involved in the development of nitroglycerin tolerance. |
NTG, PI3K, ROS |
| 42 |
2019 |
Differential Control of iNKT Cell Effector Lineage Differentiation by the Forkhead Box Protein O1 (Foxo1) Transcription Factor. |
iNKT |
| 43 |
2019 |
Expression of REGgamma in atherosclerotic plaques and promotes endothelial cells apoptosis via the cyclophilin A pathway indicates functional implications in atherogenesis. |
CyPA, ECs, HUVECs, PKAcalpha |
| 44 |
2019 |
Fibroblast growth factor 21 protects the heart from angiotensin II-induced cardiac hypertrophy and dysfunction via SIRT1. |
AMPK, Ang II, CAT, FGF21, i.p, LKB1, NRCMs, ROS, SIRT1, SIRT1-iKO |
| 45 |
2019 |
Fisetin supplementation prevents high fat diet-induced diabetic nephropathy by repressing insulin resistance and RIP3-regulated inflammation. |
FIS, GSK, HFD, IL-6, KIM-1, NCD, NF-kappaB, NLRP3, PAL, TNF-alpha |
| 46 |
2019 |
Forkhead box protein O1 (FOXO1) and paired box gene 3 (PAX3) overexpression is associated with poor prognosis in patients with cervical cancer. |
IHC, PAX3, TMA |
| 47 |
2019 |
Forkhead box protein O1 (FoxO1) regulates hepatic serine protease inhibitor B1 (serpinB1) expression in a non-cell-autonomous fashion. |
LIRKO, serpinB1 |
| 48 |
2019 |
FOXO1 associated with sensitivity to chemotherapy drugs and glial-mesenchymal transition in glioma. |
GBM, GMT |
| 49 |
2019 |
FoxO1 localizes to mitochondria of adipose tissue and is affected by nutrient stress. |
ROS |
| 50 |
2019 |
FoxO1 Overexpression Ameliorates TNF-alpha-Induced Oxidative Damage and Promotes Osteogenesis of Human Periodontal Ligament Stem Cells via Antioxidant Defense Activation. |
ECM, hPDLSCs, MDA, ROS |
| 51 |
2019 |
FoxO1 regulates leptin-induced mood behavior by targeting tyrosine hydroxylase. |
DA, STAT3, TH |
| 52 |
2019 |
FoxO1 Suppresses Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication and Controls Viral Latency. |
KS, KSHV, NAC, ROS |
| 53 |
2019 |
HDAC4 mutations cause diabetes and induce beta-cell FoxO1 nuclear exclusion. |
--- |
| 54 |
2019 |
Hypoxia-Activated PI3K/Akt Inhibits Oxidative Stress via the Regulation of Reactive Oxygen Species in Human Dental Pulp Cells. |
hDPCs, PI3K, ROS |
| 55 |
2019 |
Identification of entacapone as a chemical inhibitor of FTO mediating metabolic regulation through FOXO1. |
FTO |
| 56 |
2019 |
KY-226 Protects Blood-brain Barrier Function Through the Akt/FoxO1 Signaling Pathway in Brain Ischemia. |
BBB, ERK, PTP1B, TJ, tMCAO |
| 57 |
2019 |
LINC01018 confers a novel tumor suppressor role in hepatocellular carcinoma through sponging microRNA-182-5p. |
HCC, lncRNAs, miR-182-5p |
| 58 |
2019 |
Liver kinase B1 overexpression controls mycobacterial infection in macrophages via FOXO1/Wnt5a signaling. |
IL, LKB1, Mtb, TB |
| 59 |
2019 |
LncRNA ADAMTS9-AS2 inhibits cell proliferation and decreases chemoresistance in clear cell renal cell carcinoma via the miR-27a-3p/FOXO1 axis. |
ccRCC |
| 60 |
2019 |
lncRNA MEG3 promotes hepatic insulin resistance by serving as a competing endogenous RNA of miR-214 to regulate ATF4 expression. |
ATF4, ceRNA, HFD, MEG3, miR |
| 61 |
2019 |
Lysophosphatidylcholine-induced mitochondrial fission contributes to collagen production in human cardiac fibroblasts. |
COX-2, Drp1, HCFs, LPC, mitoROS, PGE2, PKC |
| 62 |
2019 |
Menin Upregulates FOXO1 Protein Stability by Repressing Skp2-Mediated Degradation in beta Cells. |
Skp2 |
| 63 |
2019 |
Methylphenidate alters Akt-mTOR signaling in rat pheochromocytoma cells. |
ADHD, CREB, GSK-3beta, MPH |
| 64 |
2019 |
MicroRNA-145 Regulates the Differentiation of Adipose Stem Cells Toward Microvascular Endothelial Cells and Promotes Angiogenesis. |
ASCs, ECs, vWF |
| 65 |
2019 |
miR-486-5p Inhibits Inflammatory Response, Matrix Degradation and Apoptosis of Nucleus Pulposus Cells through Directly Targeting FOXO1 in Intervertebral Disc Degeneration. |
ECM, IDD, LPS, miR-486-5p, NP |
| 66 |
2019 |
Paclitaxel alleviates monocrotaline-induced pulmonary arterial hypertension via inhibition of FoxO1-mediated autophagy. |
MCT, PAH, PASMCs, RVSP |
| 67 |
2019 |
PAR2 promotes M1 macrophage polarization and inflammation via FOXO1 pathway. |
BMDM, PAR2, qRT-PCR |
| 68 |
2019 |
Polydatin inhibits hepatocellular carcinoma via the AKT/STAT3-FOXO1 signaling pathway. |
AKT, EMT, FITC, HCC, PI, STAT3 |
| 69 |
2019 |
Poorly controlled diabetes during pregnancy and lactation activates the Foxo1 pathway and causes glucose intolerance in adult offspring. |
G6PC, PCK1, STZ |
| 70 |
2019 |
Prognostic implications of forkhead box protein O1 (FOXO1) and paired box 3 (PAX3) in epithelial ovarian cancer. |
EOC, PAX3 |
| 71 |
2019 |
Protective Effects of Dioscin Against Doxorubicin-Induced Hepatotoxicity Via Regulation of Sirt1/FOXO1/NF-kappab Signal. |
ALT, AML12, AST, BAX, BCL-2, DOX, GSH-Px, HO-1, IL-1beta, IL-6, Keap1, MDA, NF-kappaB, Nrf2, ROS, SIRT1, SOD, TNF-alpha |
| 72 |
2019 |
Radix Tetrastigma flavonoid ameliorates inflammation and prolongs the lifespan of Caenorhabditis elegans through JNK, p38 and Nrf2 pathways. |
C. elegans, COX-2, iNOS, JNK, NO, Nrf2, PQ |
| 73 |
2019 |
Regulation of programmed cell death ligand 1 expression by atypical protein kinase C lambda/iota in cutaneous angiosarcoma. |
aPKClamda, CAS, pSer218 FoxO1 |
| 74 |
2019 |
Resveratrol affects hepatic gluconeogenesis via histone deacetylase 4. |
G6PC, HDAC4, PA, PCK1, REV |
| 75 |
2019 |
SIRT1 mediates the role of RNA-binding protein QKI 5 in the synthesis of triglycerides in non-alcoholic fatty liver disease mice via the PPARalpha/FoxO1 signaling pathway. |
NAFLD, NAS, PPAR, Qki5, SIRT1, TG |
| 76 |
2019 |
The effects of SIRT1/FoxO1 on LPS induced INS-1 cells dysfunction. |
ac-FoxO1, LPS, MDA, RSV, SIRT1, SOD, TLR4 |
| 77 |
2019 |
Tomatidine Reduces Palmitate-Induced Lipid Accumulation by Activating AMPK via Vitamin D Receptor-Mediated Signaling in Human HepG2 Hepatocytes. |
ACC1, AMPK, ATGL, FAS, NAFLD, SREBP-1c |
| 78 |
2019 |
Young Blood Rescues the Cognition of Alzheimer's Model Mice by Restoring the Hippocampal Cholinergic Circuit. |
AD, REST |
| 79 |
2018 |
ADAR1 attenuates allogeneic graft rejection by suppressing miR-21 biogenesis in macrophages and promoting M2 polarization. |
--- |
| 80 |
2018 |
Cep55 overexpression causes male-specific sterility in mice by suppressing Foxo1 nuclear retention through sustained activation of PI3K/Akt signaling. |
CEP55, Egr4, ESCRT, Gfra1, PLZF, Sohlh1, TEX14 |
| 81 |
2018 |
CK2 Controls Th17 and Regulatory T Cell Differentiation Through Inhibition of FoxO1. |
--- |
| 82 |
2018 |
Dendrobium mixture regulates hepatic gluconeogenesis in diabetic rats via the phosphoinositide-3-kinase/protein kinase B signaling pathway. |
ALT, AST, DMix, FBG, G6Pase, GSP, INSR, PEPCK, PI3K, TCH, TG |
| 83 |
2018 |
Effects of intravenous AICAR (5-aminoimidazole-4-carboximide riboside) administration on insulin signaling and resistance in premature baboons, Papio sp. |
ACC, AMPK, aPKC, ERK, FBP1, G6Pase, GLUT4, INSR, IRS-1, PEPCK, PGC1alpha, SHP |
| 84 |
2018 |
Exosome-mediated transfer of lncRNA RP11‑838N2.4 promotes erlotinib resistance in non-small cell lung cancer. |
lncRNAs, NSCLC |
| 85 |
2018 |
Expression and phosphorylation of FOXO1 influences cell proliferation and apoptosis in the gastrointestinal stromal tumor cell line GIST-T1. |
Bcl-2, GISTs, MAPK, PI3K |
| 86 |
2018 |
FoxO1 Is Required for Most of the Metabolic and Hormonal Perturbations Produced by Hepatic Insulin Receptor Deletion in Male Mice. |
--- |
| 87 |
2018 |
FoxO1, A2M, and TGF-beta1: three novel genes predicting depression in gene X environment interactions are identified using cross-species and cross-tissues transcriptomic and miRNomic analyses. |
A2M, PNS, TGF-beta1 |
| 88 |
2018 |
Fusion status in patients with lymph node-positive (N1) alveolar rhabdomyosarcoma is a powerful predictor of prognosis: Experience of the European Paediatric Soft Tissue Sarcoma Study Group (EpSSG). |
ARMS, EpSSG |
| 89 |
2018 |
Galangin Inhibits Thrombin-Induced MMP-9 Expression in SK-N-SH Cells via Protein Kinase-Dependent NF-kappaB Phosphorylation. |
Akt, JNK, MAPK, MMPs, mTOR, PKC, Pyk2 |
| 90 |
2018 |
High-intensity eccentric training ameliorates muscle wasting in colon 26 tumor-bearing mice. |
CNT, ECC, ES, mTORC, MuRF-1, REDD |
| 91 |
2018 |
Inhibition of BRD4 suppresses tumor growth in prostate cancer via the enhancement of FOXO1 expression. |
Bcl-2, BRD4, PCa |
| 92 |
2018 |
Inhibitory Effect of Idelalisib, a Selective Phosphatidylinositol 3-Kinase delta Inhibitor, on Adipogenesis in an In Vitro Model of Graves' Orbitopathy. |
C/EBP, GO, mTOR, PI3K, PPARgamma |
| 93 |
2018 |
Insulin suppresses the production of fibroblast growth factor 23 (FGF23). |
FGF23, IGF-1, PI3K, PKB, PTH |
| 94 |
2018 |
Intermittent Hypoxia Disrupts Glucose Homeostasis in Liver Cells in an Insulin-Dependent and Independent Manner. |
GSK-3beta, IH, JNK, PEPCK |
| 95 |
2018 |
Leptin suppresses microRNA-122 promoter activity by phosphorylation of foxO1 in hepatic stellate cell contributing to leptin promotion of mouse liver fibrosis. |
HSC, miR-122 |
| 96 |
2018 |
Liraglutide ameliorates early renal injury by the activation of renal FoxO1 in a type 2 diabetic kidney disease rat model. |
BUN, FN, GBM, MnSOD, SCr, STZ, TGF-beta1 |
| 97 |
2018 |
Long Noncoding RNA LINC01619 Regulates MicroRNA-27a/Forkhead Box Protein O1 and Endoplasmic Reticulum Stress-Mediated Podocyte Injury in Diabetic Nephropathy. |
DN, ER, lncRNAs, miR-27a |
| 98 |
2018 |
miR15a regulates NLRP3 inflammasome proteins in the retinal vasculature. |
IL-1beta, NLRP3, REC |
| 99 |
2018 |
Pulsed electromagnetic fields alleviate streptozotocin‑induced diabetic muscle atrophy. |
Akt, DM, DP, DT, MSTN, mTOR, NC, PEMFs, SD, STZ |
| 100 |
2018 |
Qing Gan Zi Shen Tang alleviates adipose tissue dysfunction with up-regulation of SIRT1 in spontaneously hypertensive rat. |
eWAT, FABP4, HFD, MAP, PPARgamma, PTP1B, QGZST, SBP, SHR, SIRT1 |
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