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■ Abbreviation / Long Form : FPD / Familial platelet disorder

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Total Number of Papers: 11
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Abbreviation:   FPD  (>> Co-occurring Abbreviation)
Long Form:   Familial platelet disorder
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No. Year Title Co-occurring Abbreviation
2020 Distinctive phenotypes in two children with novel germline RUNX1 mutations - one with myeloid malignancy and increased fetal hemoglobin. MM
2019 RUNX1-targeted therapy for AML expressing somatic or germline mutation in RUNX1. AML, EMs, HPCs, mtRUNX1
2018 Human NOTCH4 is a key target of RUNX1 in megakaryocytic differentiation. iPSCs, MKs
2016 Application of iPS cells derived from congenital myelodysplastic syndrome for research of nomal hematopoesis and hematological malignancies. iPSCs, MDS
2016 Evaluation of Patients and Families With Concern for Predispositions to Hematologic Malignancies Within the Hereditary Hematologic Malignancy Clinic (HHMC). AML, HCS, HHMC, LFS
2014 Impaired hematopoietic differentiation of RUNX1-mutated induced pluripotent stem cells derived from FPD/AML patients. AML, iPSCs, WT
2014 Recurrent CDC25C mutations drive malignant transformation in FPD/AML. AML
2013 RUNX1, but not its familial platelet disorder mutants, synergistically activates PF4 gene expression in combination with ETS family proteins. CBFbeta, Ets-1, FLI1, PF4
2010 T cell acute lymphoblastic leukemia arising from familial platelet disorder. ALL, AML
10  2009 High frequency of RUNX1 biallelic alteration in acute myeloid leukemia secondary to familial platelet disorder. AL, AML
11  1997 CBFA2, frequently rearranged in leukemia, is not responsible for a familial leukemia syndrome. ALL, AML, SSCP