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â–  Abbreviation / Long Form : FUS / fused in sarcoma

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Total Number of Papers: 297
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Abbreviation:   FUS  (>> Co-occurring Abbreviation)
Long Form:   fused in sarcoma
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No. Year Title Co-occurring Abbreviation
2020 Altered Mitochondrial Dynamics in Motor Neuron Disease: An Emerging Perspective. ALS, FTD, LIG3, MNDs, TDP
2020 Amyloid-Forming Segment Induces Aggregation of FUS-LC Domain from Phase Separation Modulated by Site-Specific Phosphorylation. FUS-LC, NMR
2020 Analysis of FUS, PFN2, TDP-43, and PLS3 as potential disease severity modifiers in spinal muscular atrophy. PFN2, PLS3, SMA, TDP-43
2020 Cdc48/VCP and Endocytosis Regulate TDP-43 and FUS Toxicity and Turnover. ALS, TDP-43
2020 Characteristic Features of FUS Inclusions in Spinal Motor Neurons of Sporadic Amyotrophic Lateral Sclerosis. ALS, SALS, TDP-43
2020 Chorea is a pleiotropic clinical feature of mutated fused-in-sarcoma in amyotrophic lateral sclerosis. ALS
2020 Conditional depletion of Fus in oligodendrocytes leads to motor hyperactivity and increased myelin deposition associated with Akt and cholesterol activation. cKO, FALS, FTLD, OL
2020 Cytoplasmic functions of TDP-43 and FUS and their role in ALS. RBPs, TDP-43
2020 Development of disease-modifying drugs for frontotemporal dementia spectrum disorders. FTD, TAF15, TDP-43
10  2020 Extensive splicing changes in an ALS/FTD transgenic mouse model overexpressing cytoplasmic fused in sarcoma. ALS, FTD, RBPs, TDP-43, Tg
11  2020 Frontotemporal Dementia: Correlations Between Psychiatric Symptoms and Pathology. C9orf72, FTLD, TDP-43
12  2020 FUS P525L mutation causing amyotrophic lateral sclerosis and movement disorders. ALS
13  2020 FUS Recognizes G Quadruplex Structures Within Neuronal mRNAs. 3'-UTR, FMRP, mRNA, PSD-95, RGG
14  2020 Inactivation of Hippo and cJun-N-terminal Kinase (JNK) signaling mitigate FUS mediated neurodegeneration in vivo. ALS, hpo, JNK
15  2020 MiR-133a-5p inhibits androgen receptor (AR)-induced proliferation in prostate cancer cells via targeting FUsed in Sarcoma (FUS) and AR. AR, KMplot
16  2020 miR-4319 inhibited the development of thyroid cancer by modulating FUS-stabilized SMURF1. EMT, SMURF1
17  2020 Parkin expression reverses mitochondrial dysfunction in fused in sarcoma-induced amyotrophic lateral sclerosis. ALS
18  2020 Promiscuous Roles of Autophagy and Proteasome in Neurodegenerative Proteinopathies. mTOR, SOD1, TDP-43, TFEB, UPS
19  2020 RNA sequence and length contribute to RNA-induced conformational change of TLS/FUS. CCND1, pncRNA, TLS
20  2020 RNA-binding protein altered expression and mislocalization in MS. ALS, PTB, RBPs, TDP-43, TMEV
21  2020 Structural and mechanistic insights into Hsp104 function revealed by synchrotron X-ray footprinting. MD, NBD1, NTD
22  2020 The Occurrence of FUS Mutations in Pediatric Amyotrophic Lateral Sclerosis: A Case Report and Review of the Literature. ALS
23  2019 A unified mechanism for LLPS of ALS/FTLD-causing FUS as well as its modulation by ATP and oligonucleic acids. ALS, AMP, CTD, DIC, LLPS, NTD, PLD, RBPs, ssDNA
24  2019 Aberrant axon branching via Fos-B dysregulation in FUS-ALS motor neurons. ALS, MNs
25  2019 Altered calcium dynamics and glutamate receptor properties in iPSC-derived motor neurons from ALS patients with C9orf72, FUS, SOD1 or TDP43 mutations. ALS, AMPA, iPSC, MNs, SOD1, TDP-43
26  2019 Behavioural impairments in mice of a novel FUS transgenic line recapitulate features of frontotemporal lobar degeneration. ALS, FTLD
27  2019 Cancer-related genes and ALS. ALS, caz, FTLD, NPM-hMLF1
28  2019 Combined fused in sarcoma-positive (FUS+) basophilic inclusion body disease and atypical tauopathy presenting with an amyotrophic lateral sclerosis/motor neurone disease (ALS/MND)-plus phenotype. ALS/MND
29  2019 Elevated FUS levels by overriding its autoregulation produce gain-of-toxicity properties that disrupt protein and RNA homeostasis. ALS, FTD
30  2019 Expanded polyglutamine impairs normal nuclear distribution of fused in sarcoma and poly (rC)-binding protein 1 in Huntington's disease. HD, INIs
31  2019 FUS (fused in sarcoma) is a component of the cellular response to topoisomerase I-induced DNA breakage and transcriptional stress. Pol II
32  2019 FUS-mediated dysregulation of Sema5a, an autism-related gene, in FUS mice with hippocampus-dependent cognitive deficits. ALS
33  2019 Fused in sarcoma silences HIV gene transcription and maintains viral latency through suppressing AFF4 gene activation. HIV, SEC
34  2019 Fused in Sarcoma: Properties, Self-Assembly and Correlation with Neurodegenerative Diseases. ALS, FTLD, LLPS, PrLDs
35  2019 Increased FUS levels in astrocytes leads to astrocyte and microglia activation and neuronal death. ALS
36  2019 Molecular Crowding Tunes Material States of Ribonucleoprotein Condensates. LCDs, RNP
37  2019 Muscleblind acts as a modifier of FUS toxicity by modulating stress granule dynamics and SMN localization. ALS, SMN
38  2019 New Mechanisms of DNA Repair Defects in Fused in Sarcoma-Associated Neurodegeneration: Stage Set for DNA Repair-Based Therapeutics? ALS, LigIII
39  2019 Off-Label Treatment of 4 Amyotrophic Lateral Sclerosis Patients With 4-Aminopyridine. 4-AP, ALS, SOD1
40  2019 Phase separation of RNA-binding proteins in physiology and disease: An introduction to the JBC Reviews thematic series. ALS, LLPS, RBPs
41  2019 Prion-Like Propagation of Protein Misfolding and Aggregation in Amyotrophic Lateral Sclerosis. ALS, TDP-43
42  2019 Review: Molecular pathology of frontotemporal lobar degenerations. FTLD, TDP-43
43  2019 Synaptic FUS Localization During Motoneuron Development and Its Accumulation in Human ALS Synapses. ALS
44  2019 The Solution Structure of FUS Bound to RNA Reveals a Bipartite Mode of RNA Recognition with Both Sequence and Shape Specificity. RRM, ZnF
45  2019 Widespread FUS mislocalization is a molecular hallmark of amyotrophic lateral sclerosis. ALS
46  2018 A cytoplasmic long noncoding RNA LINC00470 as a new AKT activator to mediate glioblastoma cell autophagy. Co-IP, RIP
47  2018 A Regulatory Circuitry Between Gria2, miR-409, and miR-495 Is Affected by ALS FUS Mutation in ESC-Derived Motor Neurons. ALS, AMPA, MNs
48  2018 ALS mutations of FUS suppress protein translation and disrupt the regulation of nonsense-mediated decay. ALS, NMD
49  2018 ALS Yeast Models-Past Success Stories and New Opportunities. ALS, RNA, TDP-43
50  2018 Amyotrophic Lateral Sclerosis after Receiving the Human Papilloma Virus Vaccine: A Case Report of a 15-year-old Girl. ALS, HPV
51  2018 Amyotrophic Lateral Sclerosis associated FUS mutation shortens mitochondria and induces neurotoxicity. ALS, pre-mRNAs
52  2018 Astrocytes expressing ALS-linked mutant FUS induce motor neuron death through release of tumor necrosis factor-alpha. ALS, AMPAR, mutFUS, TNF-alpha, WTFUS
53  2018 Atomic structures of FUS LC domain segments reveal bases for reversible amyloid fibril formation. FUS LC
54  2018 Clinical and Genetic Features of Patients with Juvenile Amyotrophic Lateral Sclerosis with Fused in Sarcoma (FUS) Mutation. JALS, NGS
55  2018 Disruption of ER-mitochondria signalling in fronto-temporal dementia and related amyotrophic lateral sclerosis. ALS, FTD, TDP-43
56  2018 Effects of gem-dihydroperoxides against mutant copper‑zinc superoxide dismutase-mediated neurotoxicity. ALS, DHPs, ROS, TDP-43
57  2018 Formation of Toxic Oligomeric Assemblies of RNA-binding Protein: Musashi in Alzheimer's disease. AD, RBPs, TIA-1
58  2018 From Mouse Models to Human Disease: An Approach for Amyotrophic Lateral Sclerosis. ALS, SOD1, TARDBP
59  2018 FUS interacts with ATP synthase beta subunit and induces mitochondrial unfolded protein response in cellular and animal models. ---
60  2018 FUS Negatively Regulates Kaposi's Sarcoma-Associated Herpesvirus Gene Expression. KSHV, PEL
61  2018 FUS Regulates Activity of MicroRNA-Mediated Gene Silencing. ALS, miRISC
62  2018 FUS(1-359) transgenic mice as a model of ALS: pathophysiological and molecular aspects of the proteinopathy. ALS
63  2018 FUS-induced neurotoxicity in Drosophila is prevented by downregulating nucleocytoplasmic transport proteins. ALS, CCAP, FTD
64  2018 Hippo, Drosophila MST, is a novel modifier of motor neuron degeneration induced by knockdown of Caz, Drosophila FUS. Caz, hpo, MST
65  2018 Human regulatory proteins associate with non-coding RNAs from the EBV IR1 region. EBV, IR, LIN28A, NONO, sis
66  2018 Hypertonic Stress Causes Cytoplasmic Translocation of Neuronal, but Not Astrocytic, FUS due to Impaired Transportin Function. ALS, FTD
67  2018 Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation. ALS, DDR, MNs, NLS, PARP
68  2018 Importance of Functional Loss of FUS in FTLD/ALS. 3R-Tau, 4R-Tau, ALS, FTLD, GluA1, SynGAP1
69  2018 Long noncoding RNA Meg3 regulates cardiomyocyte apoptosis in myocardial infarction. AAV9, MI
70  2018 Mechanisms Associated with TDP-43 Neurotoxicity in ALS/FTLD. ALS, FTLD, hnRNP A1
71  2018 MicroRNA Metabolism and Dysregulation in Amyotrophic Lateral Sclerosis. ALS, CNS, miRNAs, TDP-43
72  2018 Mitochondrial abnormalities and disruption of the neuromuscular junction precede the clinical phenotype and motor neuron loss in hFUSWT transgenic mice. NMJ
73  2018 NEK1 loss-of-function mutation induces DNA damage accumulation in ALS patient-derived motoneurons. ALS, DDR
74  2018 Neuronal cell culture from transgenic zebrafish models of neurodegenerative disease. ALS, SCA3
75  2018 NPM-hMLF1 fusion protein suppresses defects of a Drosophila FTLD model expressing the human FUS gene. ALS, FTLD, hFUS, NPM-hMLF1
76  2018 Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites. LLPS, NMR, PY-NLS
77  2018 Pathogenic commonalities between spinal muscular atrophy and amyotrophic lateral sclerosis: Converging roads to therapeutic development. ALS, C9orf72, SMA, SMN1, SOD1, TDP-43
78  2018 Perturbations in Traffic: Aberrant Nucleocytoplasmic Transport at the Heart of Neurodegeneration. ALS, FTD, HD, HTT, NPCs, RBPs, TDP-43
79  2018 Plastic roles of phenylalanine and tyrosine residues of TLS/FUS in complex formation with the G-quadruplexes of telomeric DNA and TERRA. TERRA, TLS
80  2018 Role of the visual experience-dependent nascent proteome in neuronal plasticity. BONCAT, CPPs, RPS17
81  2018 Self-assembly of FUS through its low-complexity domain contributes to neurodegeneration. ALS
82  2018 Silencing of FUS in the common marmoset (Callithrix jacchus) brain via stereotaxic injection of an adeno-associated virus encoding shRNA. AAV-shFUS, ALS, FTLD, shFUS
83  2018 Sleep and circadian abnormalities precede cognitive deficits in R521C FUS knockin rats. ALS, KI
84  2018 Synaptic Paths to Neurodegeneration: The Emerging Role of TDP-43 and FUS in Synaptic Functions. ALS, FTD, mRNP, TDP-43
85  2018 The expression of SMN1, MART3, GLE1 and FUS genes in spinal muscular atrophy. SMA
86  2018 The prionlike domain of FUS is multiphosphorylated following DNA damage without altering nuclear localization. DNA-PK
87  2018 Topography of hemispheric white matter pathology in ten cases of neuronal intermediate filament inclusion disease. FTLD, GI, NIFID, PCG
88  2018 Transcription-Dependent Formation of Nuclear Granules Containing FUS and RNA Pol II. RNA Pol II
89  2018 Ubiquilin 2 modulates ALS/FTD-linked FUS-RNA complex dynamics and stress granule formation. ALS, FTD, SG, UBQLN2
90  2018 Yeast as a Model to Unravel Mechanisms Behind FUS Toxicity in Amyotrophic Lateral Sclerosis. ALS, FTLD
91  2017 Altered nucleocytoplasmic proteome and transcriptome distributions in an in vitro model of amyotrophic lateral sclerosis. ALS, TDP-43
92  2017 Altered Tau Isoform Ratio Caused by Loss of FUS and SFPQ Function Leads to FTLD-like Phenotypes. 3R-T, 4R-T, FTLD
93  2017 An in vitro technique to identify the RNA binding-site sequences for RNA-binding proteins. RBPs
94  2017 Clinical and experimental studies of a novel P525R FUS mutation in amyotrophic lateral sclerosis. ALS
95  2017 Dendritic Homeostasis Disruption in a Novel Frontotemporal Dementia Mouse Model Expressing Cytoplasmic Fused in Sarcoma. ALS, FTD
96  2017 Diverse Supramolecular Nanofiber Networks Assembled by Functional Low-Complexity Domains. LC
97  2017 Failure to Deliver and Translate-New Insights into RNA Dysregulation in ALS. ALS
98  2017 FUS inclusions disrupt RNA localization by sequestering kinesin-1 and inhibiting microtubule detyrosination. ALS, Glu
99  2017 Fused in Sarcoma Neuropathology in Neurodegenerative Disease. ALS
100  2017 HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients. ALS, ALS, ER, HDAC6, hESCs, iPSCs, MNs