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■ Abbreviation / Long Form : GPCRs / G protein-coupled receptors

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Abbreviation:   GPCRs  (>> Co-occurring Abbreviation)
Long Form:   G protein-coupled receptors
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No. Year Title Co-occurring Abbreviation
2020 A free-energy landscape for the glucagon-like peptide 1 receptor GLP1R. GLP-1
2020 A novel molecular mechanism involved in the crosstalks between homologous and PKC-mediated heterologous regulatory pathway of dopamine D2 receptor. PDK1, PKC
2020 Age-dependent impairment of metabotropic glutamate receptor 2-dependent long-term depression in the mouse striatum by chronic ethanol exposure. CIE, DLS, DMS, LTD, mGlu2
2020 Agonist-selective recruitment of engineered protein probes and of GRK2 by opioid receptors in living cells. ---
2020 Allosteric modulation of G protein-coupled receptors by amiloride and its derivatives. Perspectives for drug discovery? ---
2020 Analyzing GPCR-Ligand Interactions with the Fragment Molecular Orbital (FMO) Method. FMO, QM, SBDD
2020 Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR. Ang II, AT1R
2020 Anticonvulsant valproic acid and other short-chain fatty acids as novel anticancer therapeutics: Possibilities and challenges. HDAC, SCFAs, VPA
2020 Antiviral activity of sertindole, raloxifene and ibutamoren against transcription and replication-competent Ebola virus-like particles. EBOV, GHS-R, trVLP
10  2020 Autophagy mediates hepatic GRK2 degradation to facilitate glucagon-induced metabolic adaptation to fasting. GRK2
11  2020 beta-Adrenergic receptor, an essential target in cardiovascular diseases. AC, betaARK, betaARs, cAMP, CVD, CVS, GRKs, HF
12  2020 beta-Arrestin-2 BRET Biosensors Detect Different beta-Arrestin-2 Conformations in Interaction with GPCRs. BRET
13  2020 beta-Arrestin2 oligomers impair the clearance of pathological tau and increase tau aggregates. ---
14  2020 Beta-arrestins operate an on/off control switch for focal adhesion kinase activity. FAK
15  2020 Biased Signaling of the G-Protein-Coupled Receptor beta2AR Is Governed by Conformational Exchange Kinetics. beta2AR, TM VII
16  2020 Biological Activity-Based Prioritization of Pharmaceuticals in Wastewater for Environmental Monitoring: G Protein-Coupled Receptor Inhibitors. TGF alpha
17  2020 Ca2+ waves coordinate purinergic receptor-evoked integrin activation and polarization. ---
18  2020 Cell-Based In Vitro Assay Automation: Balancing Technology and Data Reproducibility/Predictability. HTRF, MRL, SAR
19  2020 Characterising Inter-helical Interactions of G Protein-Coupled Receptors with the Fragment Molecular Orbital Method. FMO, TM
20  2020 Characterization of a hyperphosphorylated variant of G protein-coupled receptor kinase 5 expressed in E. coli. GRKs
21  2020 Characterizing Rhodopsin-Arrestin Interactions with the Fragment Molecular Orbital (FMO) Method. FMO, QM, XFEL
22  2020 Cholesterol interaction motifs in G protein-coupled receptors: Slippery hot spots? ---
23  2020 Combinatorial allosteric modulation of agonist response in a self-interacting G-protein coupled receptor. ---
24  2020 Combined Computational and Structural Approach into Understanding the Role of Peptide Binding and Activation of Melanocortin Receptor 4. MC4R
25  2020 Computerized screening of G-protein coupled receptors to identify and characterize olfactory receptors. ORs
26  2020 Conformational plasticity of ligand-bound and ternary GPCR complexes studied by 19F NMR of the beta1-adrenergic receptor. ---
27  2020 Controversial Roles of Gut Microbiota-Derived Short-Chain Fatty Acids (SCFAs) on Pancreatic beta-Cell Growth and Insulin Secretion. SCFAs
28  2020 CP-25 inhibits PGE2-induced angiogenesis by down-regulating EP4/AC/cAMP/PKA-mediated GRK2 translocation. AA, CIA, ECs, ERK, GRK2, Pae, PGE2, PKA, siRNA
29  2020 Cryo-Electron Microscopy: Moving Beyond X-Ray Crystal Structures for Drug Receptors and Drug Development. GABAARs
30  2020 Deciphering Imidazoline Off-Targets by Fishing in the Class A of GPCR field. ---
31  2020 Deficiency of Prebiotic Fibre and Insufficient Signalling Through Gut Metabolite Sensing Receptors Leads to Cardiovascular Disease. BP, Treg
32  2020 Design, synthesis and biological evaluation of suramin-derived dual antagonists of the proinflammatory G protein-coupled receptors P2Y2 and GPR17. ---
33  2020 Detergent-free extraction of a functional low-expressing GPCR from a human cell line. ADHD, CNS, DRs, LQs, NT, SMA
34  2020 Development of a High-Throughput Screening-Compatible Assay for Discovery of GPR3 Inverse Agonists Using a cAMP Biosensor. CNS, HTS
35  2020 Differential effects of membrane sphingomyelin and cholesterol on agonist-induced bitter taste receptor T2R14 signaling. AT1R
36  2020 DIMERBOW: exploring possible GPCR dimer interfaces. ---
37  2020 Discovery of potential asthma targets based on the clinical efficacy of Traditional Chinese Medicine formulas. ASMCs, CFs, CM, DAVID, GO, HITD, MMPs, PPI, SHRs, STRING, TCDMD, TCM, TCMDB, TCMID, TRP, TTD
38  2020 Do All Roads Lead to Rome in G-Protein Activation? G protein
39  2020 Dynamic protein interfaces and conformational landscapes of membrane protein complexes. ---
40  2020 Effect of thermostable mutations on the neurotensin receptor 1 (NTSR1) activation state. NTS, NTSR1
41  2020 Energy Landscapes Reveal Agonist Control of G Protein-Coupled Receptor Activation via Microswitches. ---
42  2020 Engineering G protein-coupled receptor signalling in yeast for biotechnological and medical purposes. ---
43  2020 Evaluation of chemical cross-linkers for in-depth structural analysis of G protein-coupled receptors through cross-linking mass spectrometry. ---
44  2020 Exploring functional consequences of GPCR oligomerization requires a different lens. ---
45  2020 Exploring G Protein-Coupled Receptor Signaling in Primary Pancreatic Islets. ---
46  2020 Extended Human G-Protein Coupled Receptor Network: Cell-Type-Specific Analysis of G-Protein Coupled Receptor Signaling Pathways. GRKs, hGPCRnet
47  2020 Free Fatty Acid Receptors in Health and Disease. FFARs, FFAs, SCFAs
48  2020 G Protein-Coupled Receptor Pharmacology at the Single-Molecule Level. ---
49  2020 G Protein-Coupled Receptors in Asthma Therapy: Pharmacology and Drug Action. ---
50  2020 G-Protein-Coupled Receptor-Membrane Interactions Depend on the Receptor Activation State. A1AR, GaMD, POPC
51  2020 G-Protein-Coupled Receptors in CNS: A Potential Therapeutic Target for Intervention in Neurodegenerative Disorders and Associated Cognitive Deficits. CNS
52  2020 Genetic deletion of gpr27 alters acylcarnitine metabolism, insulin sensitivity, and glucose homeostasis in zebrafish. Gpr27
53  2020 Glucagon and Glucagon-like Peptide-1 Receptors: Promising Therapeutic Targets for an Effective Management of Diabetes Mellitus. cAMP, GLP-1, GPCR, SAR
54  2020 Glucagon-like peptide-1 receptor undergoes importin-alpha-dependent nuclear localization in rat aortic smooth muscle cells. GLP-1R, NLS, RASMCs
55  2020 GPCR and Alcohol-Related Behaviors in Genetically Modified Mice. AUD
56  2020 GPCR Solubilization and Quality Control. ---
57  2020 GPCRs in pancreatic adenocarcinoma: Contributors to tumor biology and novel therapeutic targets. PAAD
58  2020 GRK6 regulates the hemostatic response to injury through its rate-limiting effects on GPCR signaling in platelets. GRK6, TXA2, WT
59  2020 Holothurians have a reduced GPCR and odorant receptor-like repertoire compared to other echinoderms. ORs
60  2020 Homologous G Protein-Coupled Receptors Boost the Modeling and Interpretation of Bioactivities of Ligand Molecules. MTR-GL
61  2020 Host-Receptor Post-Translational Modifications Refine Staphylococcal Leukocidin Cytotoxicity. HlgAB, LukED, PTM, PVL
62  2020 Inhibition of store-operated calcium channels by N-arachidonoyl glycine (NAGly): no evidence for the involvement of lipid-sensing G protein coupled receptors. AEA, CNS, LPA, NAGly, S1P
63  2020 Integrated structural modeling and super-resolution imaging resolve GPCR oligomers. GPHRs, LHR, PD-PALM
64  2020 Ligand binding and activation of UTP-activated G protein-coupled P2Y2 and P2Y4 receptors elucidated by mutagenesis, pharmacological and computational studies. P2YR
65  2020 Lipid-Dependent Regulation of Ion Channels and G Protein-Coupled Receptors: Insights from Structures and Simulations. ---
66  2020 Melatonin MT1 and MT2 receptor ERK signaling is differentially dependent on Gi/o and Gq/11 proteins. ERKs
67  2020 Modulation of NMDA receptors by GPCRs: role in synaptic transmission, plasticity and beyond. NMDARs
68  2020 Molecular Basis for Hormone Recognition and Activation of Corticotropin-Releasing Factor Receptors. CRF, cryo-EM
69  2020 Molecular basis of protease-activated receptor 1 signaling diversity. PAR1, PARs
70  2020 N-(2-Hydroxyphenyl)-1-[3-(2-oxo-2,3-dihydro-1H- benzimidazol-1-yl)propyl]piperidine-4-Carboxamide (D2AAK4), a Multi-Target Ligand of Aminergic GPCRs, as a Potential Antipsychotic. EPM
71  2020 Natural allosteric modulators and their biological targets: molecular signatures and mechanisms. PCA
72  2020 Neurotransmitters and Endothelins Acting on Radial Glial G-Protein-Coupled Receptors Are, Through Proteolytic NRG/ErbB4 Activation, Able to Modify the Migratory Behavior of Neocortical Cells and Mediate Bipolar-to-Multipolar Transition. mGluR5, MMPs, NRGs, TRPC3
73  2020 Not So Dry After All: DRY Mutants of the AT1A Receptor and H1 Receptor Can Induce G-Protein-Dependent Signaling. ---
74  2020 Novel M2 -selective, Gi -biased agonists of muscarinic acetylcholine receptors. ---
75  2020 Oligomerization of G protein-coupled receptors: Still doubted? ---
76  2020 Opsin3 Downregulation Induces Apoptosis of Human Epidermal Melanocytes via Mitochondrial Pathway. Opn3
77  2020 Orphan G-protein coupled receptor 183 (GPR183) potentiates insulin secretion and prevents glucotoxicity-induced beta-cell dysfunction. GPR183
78  2020 Orphan G-Protein-Coupled Receptor GPRC5B Controls Smooth Muscle Contractility and Differentiation by Inhibiting Prostacyclin Receptor Signaling. SMC
79  2020 Oscillatory cAMP signaling rapidly alters H3K4 methylation. RapGEF2
80  2020 PAR2 mediates itch via TRPV3 signaling in keratinocytes. AD, PAR2, TRP
81  2020 Peptide hormone sensors using human hormone receptor-carrying nanovesicles and graphene FETs. FETs, GCG, GCGR, HEK293, PTH, PTHR
82  2020 Preferential Coupling of Dopamine D2S and D2L Receptor Isoforms with Gi1 and Gi2 Proteins-In Silico Study. D2S
83  2020 Probing thermostability of detergent-solubilized CB2 receptor by parallel G protein-activation and ligand-binding assays. ---
84  2020 Protease-activated receptor signalling initiates alpha5beta1-integrin-mediated adhesion in non-haematopoietic cells. ---
85  2020 Protective Effect of Genistein against Compound 48/80 Induced Anaphylactoid Shock via Inhibiting MAS Related G Protein-Coupled Receptor X2 (MRGPRX2). MRGPRX2, MRGPRX2
86  2020 Revealing Conformational Transitions in G-Protein-Coupled Receptor Rhodopsin upon Phosphorylation. ---
87  2020 Rimonabant suppresses RNA transcription of hepatitis B virus by inhibiting hepatocyte nuclear factor 4alpha. HBV, HNF4alpha, mRNAs, PHH
88  2020 Role of Actin Cytoskeleton in Dynamics and Function of the Serotonin1A Receptor. ---
89  2020 Role of cholesterol-mediated effects in GPCR heterodimers. A2A
90  2020 Site-directed labeling of beta-arrestin with monobromobimane for measuring their interaction with G protein-coupled receptors. mBBr
91  2020 Small-scale approach for precrystallization screening in GPCR X-ray crystallography. ---
92  2020 Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta. EC, LEC, S1PR1
93  2020 Src-family protein tyrosine kinases: A promising target for treating chronic pain. CFA, EGF, EphBRs, NMDAR, PNI, SFKs, STZ
94  2020 Statin-Induced Chronic Cholesterol Depletion Switches GPCR Endocytosis and Trafficking: Insights from the Serotonin1A Receptor. ---
95  2020 Structural Basis for Allosteric Modulation of Class B G Protein-Coupled Receptors. ---
96  2020 Structural basis for GPCR signaling by small polar versus largelipid metabolites-discovery of non-metabolite ligands. ---
97  2020 Structural equilibrium underlying ligand-dependent activation of beta2-adrenoreceptor. ---
98  2020 Structure and function of beta-arrestins, their emerging role in breast cancer, and potential opportunities for therapeutic manipulation. ---
99  2020 Structure of formylpeptide receptor 2-Gi complex reveals insights into ligand recognition and signaling. FPRs
100  2020 Structure of the M2 muscarinic receptor-beta-arrestin complex in a lipid nanodisc. beta-arr1