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■ Abbreviation / Long Form : GRP94 / glucose-regulated protein 94

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Total Number of Papers: 125
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Abbreviation:   GRP94  (>> Co-occurring Abbreviation)
Long Form:   glucose-regulated protein 94
 Abbreviation Variation
 Long Form Variation
 Pair(Abbreviation/Long Form) Variation
No. Year Title Co-occurring Abbreviation
2020 --GRP94 Regulates M1 Macrophage Polarization and Insulin Resistance. BMDMs, ER, HFD, KO, WT
2020 Bisubstrate-Type Chemical Probes Identify GRP94 as a Potential Target of Cytosine-Containing Adenosine Analogs. ---
2020 Erythropoietin attenuates vascular calcification by inhibiting endoplasmic reticulum stress in rats with chronic kidney disease. ATF4, CKD, EPO, EPOR, ER, VC, VSMCs
2020 Overexpression of molecule GRP94 favors tumor progression in lung adenocarcinoma by interaction with regulatory T cells. AD
2020 Perturbation of the Relative Contribution of Molecular Chaperones in the Endoplasmic Reticulum. BiP, CRT, ER
2019 Antibody-Based Targeting of Cell Surface GRP94 Specifically Inhibits Cetuximab-Resistant Colorectal Cancer Growth. CRC
2019 Bovine milk-derived exosomes enhance goblet cell activity and prevent the development of experimental necrotizing enterocolitis. ER, MUC2, NEC, TFF3
2019 Different Grp94 components interact transiently with the myocilin olfactomedin domain in vitro to enhance or retard its amyloid aggregation. ER, OLF
2019 Differential expression of HSP90 isoforms and their correlations with clinicopathologic factors in patients with colorectal cancer. CRC, Hsp90, RFS, TNF
10  2019 Effects of purine-scaffold inhibitors on HUVECs: Involvement of the purinergic pathway and interference with ATP. Implications for preventing the adverse effects of extracellular Grp94. HSP
11  2019 Endoplasmic Reticulum Chaperone Glucose-Regulated Protein 94 Is Essential for Proinsulin Handling. ER, PERK
12  2019 Glucose-Regulated Protein 94 Modulates the Response of Osteosarcoma to Chemotherapy. ER, GRP94-KD, OS, PI
13  2019 GRP94 Is Involved in the Lipid Phenotype of Brain Metastatic Cells. BrM, FA
14  2019 Low-concentration HCP1 inhibits apoptosis in vascular endothelial cells. FGF-2, Hsp90, VEC
15  2019 Overexpression of miR-150 alleviates mechanical stress-accelerated the apoptosis of chondrocytes via targeting GRP94. miRs, PI
16  2019 Profile of the unfolded protein response in rat cerebellar cortical development. ATF6, ER, GRP78, IGL, IRE1, PDI, PERK, UPR
17  2019 Sodium fluoride induces apoptosis and autophagy via the endoplasmic reticulum stress pathway in MC3T3-E1 osteoblastic cells. ER, UPR
18  2019 The involvement of DAMPs-mediated inflammation in cyclophosphamide-induced liver injury and the protection of liquiritigenin and liquiritin. CPA, DAMPs, HMGB1, HSP60, IL-6, LG, LQ, MPO, NF-kappaB, TLR4
19  2018 Chlorogenic acid against palmitic acid in endoplasmic reticulum stress-mediated apoptosis resulting in protective effect of primary rat hepatocytes. CHOP, ER, GRP78
20  2018 Glucose-regulated protein 94 mediates progression and metastasis of esophageal squamous cell carcinoma via mitochondrial function and the NF-kB/COX-2/VEGF axis. COX-2, ESCC, VEGF
21  2018 Inhibition of endoplasmic reticulum stress by intermedin1-53 attenuates angiotensin II-induced abdominal aortic aneurysm in ApoE KO Mice. AAA, AMP, Ang II, ATF4, eIF2a, ERS, IMD, Tau
22  2018 The overexpression of Hsp90B1 is associated with tumorigenesis of canine mammary glands. HSP
23  2017 Citrinin induces apoptosis in human HCT116 colon cancer cells through endoplasmic reticulum stress. CTN, ER, GRP78, MOA, PBA, PDIA6, ROS, UPR, XBP1
24  2017 Cortistatin Improves Cardiac Function After Acute Myocardial Infarction in Rats by Suppressing Myocardial Apoptosis and Endoplasmic Reticulum Stress. AMI, CST, ER, GRP78
25  2017 Isoform-selective Hsp90 inhibition rescues model of hereditary open-angle glaucoma. Hsp90
26  2017 Resorcinol-Based Grp94-Selective Inhibitors. ---
27  2017 Second Generation Grp94-Selective Inhibitors Provide Opportunities for the Inhibition of Metastatic Cancer. ER
28  2017 Upregulation of endoplasmic reticulum stress is associated with diaphragm contractile dysfunction in a rat model of sepsis. CHOP, ER, ERP44, GRP78
29  2017 [Effect of oxidative stress on myocardial apoptosis, endoplasmic reticulum stress and apoptosis factor in suckling mouse atria myocardium]. bax, bcl-2, CHOP, GRP78, MDA, SOD
30  2016 A Human Variant of Glucose-Regulated Protein 94 That Inefficiently Supports IGF Production. ---
31  2016 Atf6alpha deficiency suppresses microglial activation and ameliorates pathology of experimental autoimmune encephalomyelitis. ATF6alpha, EAE, GRP78, MS
32  2016 Development of Glucose Regulated Protein 94-Selective Inhibitors Based on the BnIm and Radamide Scaffold. Hsp90
33  2016 Endoplasmic Reticulum-resident Heat Shock Protein 90 (HSP90) Isoform Glucose-regulated Protein 94 (GRP94) Regulates Cell Polarity and Cancer Cell Migration by Affecting Intracellular Transport. Hsp90
34  2016 Glucose-regulated protein 94 deficiency induces squamous cell metaplasia and suppresses PTEN-null driven endometrial epithelial tumor development. EAC, SCM
35  2016 Glucose-regulated protein 94 mediates cancer progression via AKT and eNOS in hepatocellular carcinoma. HCC, shRNA
36  2016 Glucose-regulated protein 94 mediates metastasis by CCT8 and the JNK pathway in hepatocellular carcinoma. HCC, shRNA
37  2016 Grp94 in complexes with IgG is a soluble diagnostic marker of gastrointestinal tumors and displays immune-stimulating activity on peripheral blood immune cells. ER, GI, HSP, Ig, PBMCs
38  2016 GRP94/gp96 in Cancer: Biology, Structure, Immunology, and Drug Development. Hsp90
39  2016 Oxygen-Glucose Deprivation (OGD) Modulates the Unfolded Protein Response (UPR) and Inflicts Autophagy in a PC12 Hypoxia Cell Line Model. GRP75, GRP78, Hsc70, OGD, UPR, UPR
40  2016 Sodium fluoride (NaF) induces the splenic apoptosis via endoplasmic reticulum (ER) stress pathway in vivo and in vitro. 4-PBA, cleaved caspase-12, ER, p-JNK, UPR
41  2015 Calcium-independent phospholipase A2gamma enhances activation of the ATF6 transcription factor during endoplasmic reticulum stress. ATF6, ER, GECs, GRP78, iPLA2gamma, UPR
42  2015 Differential expression of heat shock protein 90 isoforms in small cell lung cancer. Hsp90, SCLC, TNF
43  2015 Genetic ablation of N-linked glycosylation reveals two key folding pathways for R345W fibulin-3, a secreted protein associated with retinal degeneration. ER, GRP78, WT
44  2015 Glucose-regulated protein 94 is a novel glioma biomarker and promotes the aggressiveness of glioma via Wnt/beta-catenin signaling pathway. ---
45  2015 Hepatic Overexpression of GRP94 in a Rabbit Model of Parenteral Nutrition-Associated Liver Disease. ERS, PNALD, TPN
46  2015 New Mechanism of Hepatic Fibrogenesis: Hepatitis C Virus Infection Induces Transforming Growth Factor beta1 Production through Glucose-Regulated Protein 94. HCV, TGF-beta1
47  2015 Proteomic Investigation on Grp94-IgG Complexes Circulating in Plasma of Type 1 Diabetic Subjects. ---
48  2015 Recombinant LPG3 Stimulates IFN-Gamma and TNF-A Secretion by Human NK Cells. CT, IFN, LPG3, MACS, NK, NT, rLPG3, TNF
49  2015 Recombinant LPG3 Stimulates IFN-Gamma and TNF-Alpha Secretion by Human NK Cells. CT, IFN, LPG3, MACS, NK, NT, rLPG3, TNF
50  2014 Curcumin counteracts loss of force and atrophy of hindlimb unloaded rat soleus by hampering neuronal nitric oxide synthase untethering from sarcolemma. ---
51  2014 Glucose-regulated protein 94 modulates the therapeutic efficacy to taxane in cervical cancer cells. GRP94-KD
52  2014 GRP94 is encoded by two differentially expressed genes during development of rainbow trout (Oncorhynchus mykiss). ER, TLRs
53  2014 Involvement of the Akt signaling pathway in ER-alpha36/GRP94-mediated signaling in gastric cancer. ER-alpha36
54  2014 Liver-specific knockout of GRP94 in mice disrupts cell adhesion, activates liver progenitor cells, and accelerates liver tumorigenesis. CC, ER, HCC
55  2014 OS-9 facilitates turnover of nonnative GRP94 marked by hyperglycosylation. ER, ERAD, OS-9
56  2014 Parenteral nutrition-associated liver injury and increased GRP94 expression prevented by omega-3 fish oil-based lipid emulsion supplementation. TPN-FO, TPN-soy
57  2014 Structural insights into complexes of glucose-regulated Protein94 (Grp94) with human immunoglobulin G. relevance for Grp94-IgG complexes that form in vivo in pathological conditions. ---
58  2014 Targeted deletion of ER chaperone GRP94 in the liver results in injury, repopulation of GRP94-positive hepatocytes, and spontaneous hepatocellular carcinoma development in aged mice. DRs, EMT, HCC, LPC
59  2013 Identification of cisplatin-binding proteins using agarose conjugates of platinum compounds. Hsp90, VCP
60  2013 Involvement of ER-alpha36 in the malignant growth of gastric carcinoma cells is associated with GRP94 overexpression. ER-alpha36
61  2013 Iron depletion increases manganese uptake and potentiates apoptosis through ER stress. CHOP, Mn, phospho-eIF2alpha
62  2013 Melatonin treatment reduces endoplasmic reticulum stress and modulates the unfolded protein response in rabbits with lethal fulminant hepatitis of viral origin. ATF6, CHOP, ER, FHF, IRE1, JNK, RHDV, TRAF2, UPR
63  2013 Picosecond pulsed electric fields induce apoptosis in HeLa cells via the endoplasmic reticulum stress and caspase-dependent signaling pathways. C/EBP, GRP78, PEF, psPEF
64  2013 SNP discovery and High Resolution Melting Analysis from massive transcriptome sequencing in the California red abalone Haliotis rufescens. AL, FBA, HRMA, HSP70, ODC, S1AP, SNP, VTG
65  2013 Unfolded protein response and activated degradative pathways regulation in GNE myopathy. AbetaPP, ERAD, ERS, GRP78, p-tau, UPR, UPS, VCP
66  2013 [The expression and significance of unfolded protein response-related gene in synovial fluid macrophages in patients with spondyloarthritis and other arthritis]. BiP, CHOP, ERdj4, GADD34, OA, PCR, RA, SpA, UPR, XBP1
67  2012 Deletion of muscle GRP94 impairs both muscle and body growth by inhibiting local IGF production. IGFs
68  2012 Effects of porcine circovirus type 2 on expression of mRNA associated with endogenous antigen processing and presentation in pulmonary alveolar macrophages and circulating T lymphocytes in piglets. FCM, LMP7, MHC-I, PAMs, PCV2, Th, UBP
69  2012 ER Stress Proteins in Autoimmune and Inflammatory Diseases. BiP, ER, Grp170, GRP78, Herp, HSP47, HSPs, ORP150
70  2012 Glucose-regulated protein 94 triage of mutant myocilin through endoplasmic reticulum-associated degradation subverts a more efficient autophagic clearance mechanism. ER, ERAD, GRP, Hsp90
71  2012 Inhibition of immunoglobulin secretion from peripheral blood mononuclear cells by glucose-regulated protein94 (Grp94) in allergic subjects. PBMCs
72  2012 Lipid peroxidation, antioxidant activities and stress protein (HSP72/73, GRP94) expression in kidney and liver of rats under lithium treatment. hsp73
73  2012 Oxidative stress induces unfolding protein response and inflammation in nasal polyposis. GRP78, IL-8, LTB4, NP, sXBP-1, UPR
74  2012 Protein phosphorylation on tyrosine restores expression and glycosylation of cyclooxygenase-2 by 2-deoxy-D-glucose-caused endoplasmic reticulum stress in rabbit articular chondrocyte. 2-DG, ER, PAO, PTP, SOV
75  2012 Release of the glucose-regulated protein 94 by baby hamster kidney cells. ER
76  2012 Serum levels of RBP4 and adipose tissue levels of PTP1B are increased in obese men resident in northeast Scotland without associated changes in ER stress response genes. ATF4, BiP, BMI, ER, PTP1B, RBP4
77  2011 alpha-Linolenic acid prevents endoplasmic reticulum stress-mediated apoptosis of stearic acid lipotoxicity on primary rat hepatocytes. CHOP, ER, GRP78, NAFLD
78  2011 Crucial role of HSP90 in the Akt-dependent promotion of angiogenic-like effect of glucose-regulated protein94 (Grp94)-IgG complexes. HSP, HUVECs, MMP-9, PI3K, PU
79  2011 Effects of glucose-regulated protein94 (Grp94) on Ig secretion from human blood mononuclear cells. HSP, PBMCs
80  2011 Evaluation of DNA/DNA and prime-boost vaccination using LPG3 against Leishmania major infection in susceptible BALB/c mice and its antigenic properties in human leishmaniasis. CL, HSP, LPG3, rNT-LPG3, VL
81  2011 Liver-specific deletion of protein tyrosine phosphatase (PTP) 1B improves obesity- and pharmacologically induced endoplasmic reticulum stress. ATF4, BiP, ER, GADD34, HFD, L-PTP1B, PTP, PTP1B, XBP1
82  2011 Stimulation of CK2-dependent Grp94 phosphorylation by the nuclear localization signal peptide. ER, NLS
83  2010 Antibodies to the endoplasmic reticulum-resident chaperones calnexin, BiP and Grp94 in patients with rheumatoid arthritis and systemic lupus erythematosus. BiP, ER
84  2010 ER stress induced by ionising radiation in IEC-6 cells. ATF6, BiP, ER, IR, IRE1, XBP1
85  2010 GRP94 in ER quality control and stress responses. ER, ERAD
86  2010 Lead induces the expression of endoplasmic reticulum chaperones GRP78 and GRP94 in vascular endothelial cells via the JNK-AP-1 pathway. AP-1, ER, GRP78, IRE1, JNK, siRNA, UPR
87  2010 Targeted mutation of the mouse Grp94 gene disrupts development and perturbs endoplasmic reticulum stress signaling. ER, Hsp90, KO
88  2010 [Effect of endoplasmic reticulum stress-responsive protein glucose-regulated protein 78, 94 and endoplasmic reticulum apoptosis factor caspase-12 in trophocyte on the pathogenesis of preeclampsia]. GRP78, PE, RT
89  2010 [Expression of GRP78 and GRP94 in the liver tissues and their clinicopathological significance in children with hepatoblastoma]. GRP78, HB
90  2010 [Oxidized low density lipoprotein induces macrophage endoplasmic reticulum stress via CD36.]. ERS, oxLDL, p-IRE1, TM, XBP1
91  2009 An essential role for ATP binding and hydrolysis in the chaperone activity of GRP94 in cells. ER, IGF, mGFP
92  2008 A molecular chaperone glucose-regulated protein 94 blocks apoptosis induced by virus infection. FLIP, HCV, NF-kappaB, siRNA, TRAIL, XIAP
93  2008 Cytokine-induced beta-cell death is independent of endoplasmic reticulum stress signaling. ATF, CHOP, eIF, ER, IFN-gamma, IL, PBA, PERK, siRNA, XBP1
94  2008 Increased expression of GRP94 protein is associated with decreased sensitivity to adriamycin in ovarian carcinoma cell lines. ---
95  2008 [Expression of Hsp70 Grp94 and IgG in human lung carcinoma]. HSP70, IgG
96  2007 Apoptosis induced by staurosporine alters chaperone and endoplasmic reticulum proteins: Identification by quantitative proteomics. AIP1, CAF-1, GRP78, HSC-71, HSP70, PDI A3, STS
97  2007 GRP94 is essential for mesoderm induction and muscle development because it regulates insulin-like growth factor secretion. ---
98  2007 Network-based analysis of calcium-binding protein genes identifies Grp94 as a target in human oral carcinogenesis. OPLs, OSCCs
99  2007 Reduction of GRP78 expression with siRNA activates unfolded protein response leading to apoptosis in HeLa cells. ER, UPR
100  2007 The peptide-binding activity of GRP94 is regulated by calcium. ---