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■ Abbreviation / Long Form : GS / gamma-secretase

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Total Number of Papers: 15
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Abbreviation:   GS  (>> Co-occurring Abbreviation)
Long Form:   gamma-secretase
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No. Year Title Co-occurring Abbreviation
2019 APH-1A Component of gamma-Secretase Forms an Internal Water and Ion-Containing Cavity. APH-1A, GPCRs
2019 Toward the Characterization of DAPT Interactions with gamma-Secretase. ---
2018 Complexity and Selectivity of gamma-Secretase Cleavage on Multiple Substrates: Consequences in Alzheimer's Disease and Cancer. AbetaPP, AD, PSEN1
2018 Extending a Systems Model of the APP Pathway: Separation of beta- and gamma-Secretase Sequential Cleavage Steps of APP. APP, BACE1
2018 Influence of membrane lipid composition on the structure and activity of gamma-secretase. AD, APP
2017 CRISPR Transcriptional Activation Analysis Unmasks an Occult gamma-Secretase Processivity Defect in Familial Alzheimer's Disease Skin Fibroblasts. APP, FAD, PSEN
2017 Gamma secretase inhibitors: a patent review (2013 - 2015). ---
2016 Physiological and pathological roles of the gamma-secretase complex. APP
2014 Anti-nicastrin monoclonal antibodies elicit pleiotropic anti-tumour pharmacological effects in invasive breast cancer cells. mAbs, NCSTN
10  2013 Impaired Notch-MKP-1 signalling in hidradenitis suppurativa: an approach to pathogenesis by evidence from translational biology. HS, MKP-1
11  2013 The role of Notch and gamma-secretase inhibition in an ovarian cancer model. MTT, qPCR
12  2013 Toward a general predictive QSAR model for gamma-secretase inhibitors. NN
13  2012 Nicastrin regulates breast cancer stem cell properties and tumor growth in vitro and in vivo. BC, BCSC, NCT
14  2011 Biological and clinical implications of nicastrin expression in invasive breast cancer. BC, TMAs
15  2010 Gamma-secretase complexes regulate the responses of human pancreatic ductal adenocarcinoma cells to taxanes. GSIs, PDAC, PS1