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■ Abbreviation / Long Form : GS / guggulsterone

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Total Number of Papers: 26
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Abbreviation:   GS  (>> Co-occurring Abbreviation)
Long Form:   guggulsterone
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No. Year Title Co-occurring Abbreviation
2019 Guggulsterone Activates Adipocyte Beiging through Direct Effects on 3T3-L1 Adipocytes and Indirect Effects Mediated through RAW264.7 Macrophages. ---
2018 Guggulsterone, a farnesoid X receptor antagonist lowers plasma trimethylamine- N-oxide levels: An evidence from in vitro and in vivo studies. AS, HPLC, LC, MS, TMA, TMAO
2018 In-vitro metabolism, CYP profiling and metabolite identification of E- and Z- guggulsterone, a potent hypolipidmic agent. FXR
2017 Estimation of Guggulsterone E and Z in the Guggul-based Commercial Formulations Using High-performance Thin-layer Chromatography. ---
2017 Potential therapeutic targets of Guggulsterone in cancer. ---
2016 Anti-inflammatory effects of guggulsterone on murine macrophage by inhibiting LPS-induced inflammatory cytokines in NF-kappaB signaling pathway. ERK, IkappaB, IL-1beta, iNOS, JNK, LPS, NF-kappaB, PCR, TNF-alpha
2016 Guggulsterone Attenuated Lipopolysaccharide-Induced Inflammatory Responses in Mouse Inner Medullary Collecting Duct-3 Cells. COX-2, IL-6, iNOS, LPS, mIMCD-3, TNF-alpha
2016 Morphologic Damage of Rat Alveolar Epithelial Type II Cells Induced by Bile Acids Could Be Ameliorated by Farnesoid X Receptor Inhibitor Z-Guggulsterone In Vitro. AECIIs, BAs, CDCA, FXR
2015 Guggulsterone attenuates cerulein-induced acute pancreatitis via inhibition of ERK and JNK activation. AP, ERK, JNK, MPO
10  2014 Guggulsterone, a plant-derived inhibitor of NF-TB, suppresses CDX2 and COX-2 expression and reduces the viability of esophageal adenocarcinoma cells. BE, CDX2, COX-2, DCA, EAC, NF-kappaB, PGE2
11  2013 Cancer chemopreventive and therapeutic potential of guggulsterone. ---
12  2013 Guggulsterone decreases proliferation and metastatic behavior of pancreatic cancer cells by modulating JAK/STAT and Src/FAK signaling. PC
13  2012 Guggulsterone induces heme oxygenase-1 expression through activation of Nrf2 in human mammary epithelial cells: PTEN as a putative target. ARE, HO-1, Nrf2, PI3K
14  2012 Protective effect of guggulsterone against cardiomyocyte injury induced by doxorubicin in vitro. DOX, LDH, ROS
15  2011 Guggulsterone (GS) inhibits smokeless tobacco and nicotine-induced NF-kappaB and STAT3 pathways in head and neck cancer cells. COX-2, HNSCC, NF-kappaB, STAT
16  2011 Guggulsterone targets smokeless tobacco induced PI3K/Akt pathway in head and neck cancer cells. ST
17  2011 Guggulsterone-mediated enhancement of radiosensitivity in human tumor cell lines. DSB
18  2010 14-3-3 zeta is a molecular target in guggulsterone induced apoptosis in head and neck cancer cells. HNSCC, PARP, PP2A
19  2009 Anti-obesity effects of xanthohumol plus guggulsterone in 3T3-L1 adipocytes. XN
20  2009 The plant sterol guggulsterone attenuates inflammation and immune dysfunction in murine models of inflammatory bowel disease. CD, IBD, TNBS, UC
21  2008 Guggulsterone inhibits adipocyte differentiation and induces apoptosis in 3T3-L1 cells. ELISA, PPARgamma2
22  2008 Guggulsterone, a farnesoid X receptor antagonist, inhibits constitutive and inducible STAT3 activation through induction of a protein tyrosine phosphatase SHP-1. STAT3
23  2007 Enhanced effects of guggulsterone plus 1,25(OH)2D3 on 3T3-L1 adipocytes. ---
24  2007 Enhanced pro-apoptotic and anti-adipogenic effects of genistein plus guggulsterone in 3T3-L1 adipocytes. ---
25  2005 The hypolipidemic natural product guggulsterone is a promiscuous steroid receptor ligand. AR, ER, FXR, GR, MR, PR
26  2003 Guggulsterone is a farnesoid X receptor antagonist in coactivator association assays but acts to enhance transcription of bile salt export pump. BSEP, CYP7A1, FXR, IBABP, SHP