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■ Abbreviation / Long Form : HDACi / HDAC inhibitors

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Total Number of Papers: 277
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Abbreviation:   HDACi  (>> Co-occurring Abbreviation)
Long Form:   HDAC inhibitors
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No. Year Title Co-occurring Abbreviation
2022 A Class I HDAC Inhibitor Rescues Synaptic Damage and Neuron Loss in APP-Transfected Cells and APP/PS1 Mice through the GRIP1/AMPA Pathway. AD, AMPA, APP, GluR2, GRIP1, HDAC, SYP
2022 A diverse English keyword search reveals the value of scriptaid treatment for porcine embryo development following somatic cell nuclear transfer. HDAC, SCNT
2022 Development of Fluorinated Peptoid-Based Histone Deacetylase (HDAC) Inhibitors for Therapy-Resistant Acute Leukemia. HDAC
2022 Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AML. AML, HDAC, IFN, pDC
2022 Evaluation of Small-Molecule HDAC Inhibitors Through In Vitro and In Cellulo Approaches. ADME, HDACs, PAMPA
2022 HDAC Inhibition as Neuroprotection in COVID-19 Infection. CNS
2022 Histone Deacetylase (HDAC) Inhibitors: A Promising Weapon to Tackle Therapy Resistance in Melanoma. HDAC
2022 Lysine Acetylation/Deacetylation Modification of Immune-Related Molecules in Cancer Immunotherapy. HATs, HDACs, PTMs
2022 Mechanism of histone deacetylases in cardiac hypertrophy and its therapeutic inhibitors. GATA4, HAT, HDAC, Inpp5f, KLF4, MEF2, NFAT
10  2022 Molecular mechanisms of histone deacetylases and inhibitors in renal fibrosis progression. ECM, EMT, HDACs
11  2022 Novel Function of Avian p53 in Binding to ALV-J LTR Contributes to Its Antiviral Roles. ALV, RSV
12  2022 Repression of the PRELP gene is relieved by histone deacetylase inhibitors through acetylation of histone H2B lysine 5 in bladder cancer. PRELP
13  2022 Restoring erectile function by combined treatment with JNK inhibitor and HDAC inhibitor in a rat model of cavernous nerve injury. CN, CNCI, ED, JNKi, MAP, SAHA, SM, TGF
14  2022 SAHA Enhances Differentiation of CD34+CD45+ Hematopoietic Stem and Progenitor Cells from Pluripotent Stem Cells Concomitant with an Increase in Hemogenic Endothelium. HDAC, HE, HSCs, HSPCs, NK, PSCs
15  2022 Short chain fatty acid, acetate restores ovarian function in experimentally induced PCOS rat model. HDAC, PCOS
16  2022 Synthesis, Molecular Docking and Biological Characterization of Pyrazine Linked 2-Aminobenzamides as New Class I Selective Histone Deacetylase (HDAC) Inhibitors with Anti-Leukemic Activity. AML, HDAC, HDACs, SAR
17  2022 Targeting Histone Deacetylases: Opportunities for Cancer Treatment and Chemoprevention. HDAC
18  2022 The emerging roles of HDACs and their therapeutic implications in cancer. HATs, HDACs
19  2022 The HDAC inhibitor CI-994 acts as a molecular memory aid by facilitating synaptic and intracellular communication after learning. CFC, ChIP-seq, DG
20  2022 The novel histone deacetylase inhibitor pracinostat suppresses the malignant phenotype in human glioma. GTEx, HDACs, TCGA
21  2022 Transcriptomic analysis reveals the key role of histone deacetylation via mediating different phytohormone signalings in fiber initiation of cotton. ABA, GA, JA, TSA
22  2022 Transcriptomic and genomic studies classify NKL54 as a histone deacetylase inhibitor with indirect influence on MEF2-dependent transcription. TSS
23  2022 VPA and TSA Interrupt the Interplay between mutp53 and HSP70, Leading to CHK1 and RAD51 Down-Regulation and Sensitizing Pancreatic Cancer Cells to AZD2461 PARP Inhibitor. ---
24  2021 Alteration of MDM2 by the Small Molecule YF438 Exerts Antitumor Effects in Triple-Negative Breast Cancer. HDAC, MDM2, TNBC
25  2021 Biocompatible valproic acid-coupled nanoparticles attenuate lipopolysaccharide-induced inflammation. CV-S, HATs, HDACs, NPs, VPA
26  2021 Broad-Spectrum HDAC Inhibitors Promote Autophagy through FOXO Transcription Factors in Neuroblastoma. HDACs
27  2021 Class I histone deacetylases (HDAC) critically contribute to Ewing sarcoma pathogenesis. EEDi, EWS, HDAC
28  2021 Classical HDACs in the regulation of neuroinflammation. HDACs
29  2021 DNA-PKcs inhibition impairs HDAC6-mediated HSP90 chaperone function on Aurora A and enhances HDACs inhibitor-induced cell killing by increasing mitotic aberrant spindle assembly. DNA-PKcs, HDACs
30  2021 Downregulation of Cell Cycle and Checkpoint Genes by Class I HDAC Inhibitors Limits Synergism with G2/M Checkpoint Inhibitor MK-1775 in Bladder Cancer Cells. HDAC, UC, UCC
31  2021 From natural products to HDAC inhibitors: An overview of drug discovery and design strategy. HDACs
32  2021 HDAC inhibition potentiates anti-tumor activity of macrophages and enhances anti-PD-L1-mediated tumor suppression. MDSCs, TAMs, TME, TSA
33  2021 HDAC inhibition results in widespread alteration of the histone acetylation landscape and BRD4 targeting to gene bodies. HATs, HDACs
34  2021 HDAC Screening Identifies the HDAC Class I Inhibitor Romidepsin as a Promising Epigenetic Drug for Biliary Tract Cancer. BTC, HDACs
35  2021 Histone Deacetylase Inhibitors as Therapeutic Interventions on Cervical Cancer Induced by Human Papillomavirus. HAT, HDAC, HPVs, HR
36  2021 KDELR2 promotes breast cancer proliferation via HDAC3-mediated cell cycle progression. CREB1, HDACs, POC5, qRT-PCR
37  2021 Mechanisms Contributing to the Dysregulation of miRNA-124 in Pulmonary Hypertension. HAT, miR-124, PH, PH-Fibs
38  2021 MS-275 (Entinostat) Promotes Radio-Sensitivity in PAX3-FOXO1 Rhabdomyosarcoma Cells. FN, RMS, RT
39  2021 Rational Design and Development of HDAC Inhibitors for Breast Cancer Treatment. ---
40  2021 Sodium phenylbutyrate inhibits Schwann cell inflammation via HDAC and NFκB to promote axonal regeneration and remyelination. HDACs, LPS, MBP, NF-kappaB, PBA, PGP 9.5, SCs, TNF-alpha
41  2021 Structure-based virtual screening for novel potential selective inhibitors of class IIa histone deacetylases for cancer treatment. ADMET, HDAC, MD
42  2021 Sulforaphane attenuates cisplatin-induced hearing loss by inhibiting histone deacetylase expression. ABR, CIHL, HAT/HDAC, SFN
43  2021 Targeting the Interplay between HDACs and DNA Damage Repair for Myeloma Therapy. DDR, HDAC, MM, PTM
44  2021 Targeting the T-Cell Lymphoma Epigenome Induces Cell Death, Cancer Testes Antigens, Immune-Modulatory Signaling Pathways. DNMT, HDAC, PTCL
45  2021 Upregulation of ERK-EGR1-heparanase axis by HDAC inhibitors provides targets for rational therapeutic intervention in synovial sarcoma. HDACs, SS
46  2021 Valproic Acid Prodrug Affects Selective Markers, Augments Doxorubicin Anticancer Activity and Attenuates Its Toxicity in a Murine Model of Aggressive Breast Cancer. DOX, HDAC, Rom, VPA
47  2020 Application of Histone Deacetylase Inhibitors in Renal Interstitial Fibrosis. HDACs
48  2020 CAY10683 and imatinib have synergistic effects in overcoming imatinib resistance via HDAC2 inhibition in chronic myeloid leukemia. CML, HDACs, IM
49  2020 Differential effects of HDAC inhibitors on PPN oscillatory activity in vivo. PPN, RAS
50  2020 Epigenetic Evaluation of N-(2-hydroxyphenyl)-2-Propylpentanamide, a Valproic Acid Aryl Derivative with Activity Against HeLa Cells. VPA
51  2020 HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in Medulloblastoma. CSCs, HDAC, MAPK, MB, NSCs
52  2020 HDAC3 Mediates the Inflammatory Response and LPS Tolerance in Human Monocytes and Macrophages. HDACs
53  2020 HDACi mediate UNG2 depletion, dysregulated genomic uracil and altered expression of oncoproteins and tumor suppressors in B- and T-cell lines. ---
54  2020 Histone Deacetylase Inhibition in Non-small Cell Lung Cancer: Hype or Hope? HATs, HDACs, NSCLC
55  2020 Histone deacetylase inhibitors induce medulloblastoma cell death independent of HDACs recruited in REST repression complexes. HDAC, REST
56  2020 Histone Deacetylases and Histone Deacetylase Inhibitors in Neuroblastoma. HDACs
57  2020 Impact of HDAC Inhibitors on Protein Quality Control Systems: Consequences for Precision Medicine in Malignant Disease. BRD, HAT, HDAC, PQC, PTM, UPS
58  2020 Liver-Targeting Class I Selective Histone Deacetylase Inhibitors Potently Suppress Hepatocellular Tumor Growth as Standalone Agents. HAT, HDACs
59  2020 Non-histone substrates of histone deacetylases as potential therapeutic targets in epilepsy. AEDs, HDACs
60  2020 Optimal therapeutic targeting by HDAC inhibition in biopsy-derived treatment-naive diffuse midline glioma models. COL20A1, DIPGs, DMGs, TNNT1
61  2020 PTG-0861: A novel HDAC6-selective inhibitor as a therapeutic strategy in acute myeloid leukaemia. HDAC, PK
62  2020 Pyrimethamine conjugated histone deacetylase inhibitors: Design, synthesis and evidence for triple negative breast cancer selective cytotoxicity. HDAC, PYM, STAT3
63  2020 The combination of histone deacetylase inhibitors and radiotherapy: a promising novel approach for cancer treatment. ---
64  2020 The inhibitory effects of class I histone deacetylases on hippocampal neuroinflammatory regulation in aging mice with postoperative cognitive dysfunction. HDACs, POCD, WB
65  2020 The Role of HDACs and HDACi in Cartilage and Osteoarthritis. OA
66  2020 Trichostatin A augments esophageal squamous cell carcinoma cells migration by inducing acetylation of RelA at K310 leading epithelia-mesenchymal transition. EMT, ESCC, HDACs, TSA
67  2020 Updating a Strategy for Histone Deacetylases and Its Inhibitors in the Potential Treatment of Cerebral Ischemic Stroke. HATs, HDAC, HDACs
68  2019 4-phenylbutyric acid promotes migration of gastric cancer cells by histone deacetylase inhibition-mediated IL-8 upregulation. 4-PBA, EMT, HATs, HDACs
69  2019 Class I-Histone Deacetylase (HDAC) Inhibition is Superior to pan-HDAC Inhibition in Modulating Cisplatin Potency in High Grade Serous Ovarian Cancer Cell Lines. HDAC, HGSOC
70  2019 Decreased DHRS2 expression is associated with HDACi resistance and poor prognosis in ovarian cancer. HDACs, OC
71  2019 DNA Damage Changes Distribution Pattern and Levels of HP1 Protein Isoforms in the Nucleolus and Increases Phosphorylation of HP1beta-Ser88. HP1, KAP1, S88ph
72  2019 Effects of Histone Deacetylase Inhibitors on the Development of Epilepsy and Psychiatric Comorbidity in WAG/Rij Rats. EEG, HDACs, NaB, VPA
73  2019 Epigenetics of B-ALL. B-ALL, DNMTi, HAT, HATi, HDAC
74  2019 Fimepinostat, a novel dual inhibitor of HDAC and PI3K, effectively reverses HIV-1 latency ex vivo without T cell activation. cART, HDAC, HIV-1, PI3K
75  2019 HDAC3 Regulates Gingival Fibroblast Inflammatory Responses in Periodontitis. GFs, HDACs, SAHA
76  2019 HDAC6 Modulates Signaling Pathways Relevant to Synaptic Biology and Neuronal Differentiation in Human Stem-Cell-Derived Neurons. HDAC, HDAC6, HDAC6i, PFC
77  2019 Histone deacetylase 1 (HDAC1): A key player of T cell-mediated arthritis. CCR6, CIA, HDAC1, HDAC1, HDACs, RA
78  2019 Histone Deacetylase Inhibitors and Anaplastic Thyroid Carcinoma. ATC, HDAC, HNHA
79  2019 Histone deacetylase inhibitors exert anti-tumor effects on human adherent and stem-like glioma cells. GBM, HDAC
80  2019 Novel alpha,beta-unsaturated hydroxamic acid derivatives overcome cisplatin resistance. ---
81  2019 Restoring T Cell Tolerance, Exploring the Potential of Histone Deacetylase Inhibitors for the Treatment of Juvenile Idiopathic Arthritis. HDACs, JIA, Teff, Treg
82  2019 Role of Natural Products in Modulating Histone Deacetylases in Cancer. HDACs
83  2019 Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells. HDACs
84  2019 Structurally Diverse Histone Deacetylase Photoreactive Probes: Design, Synthesis, and Photolabeling Studies in Live Cells and Tissue. HDAC, PRPs
85  2018 A translational perspective on histone acetylation modulators in psychiatric disorders. HDAC, HDACis
86  2018 Combinatorial effects of histone deacetylase inhibitors (HDACi), vorinostat and entinostat, and adaphostin are characterized by distinct redox alterations. ALL, HDACs, NAC
87  2018 Histone deacetylase inhibitor ITF2357 (givinostat) reverts transformed phenotype and counteracts stemness in in vitro and in vivo models of human glioblastoma. GBM, GFAP, HDACs
88  2018 Histone deacetylase inhibitor treated cell sheet from mouse tendon stem/progenitor cells promotes tendon repair. HDAC, TSA, TSPCs, VPA
89  2018 Histone deacetylase inhibitor-based chromatin precipitation for identification of targeted genomic loci. ChIP, HDAC
90  2018 Histone deacetylase inhibitors suppress transdifferentiation of gonadotrophs to prolactin cells and proliferation of prolactin cells induced by diethylstilbestrol in male mouse pituitary. DES, FSH, LH, PRL, VPA
91  2018 Histone deacetylases (HDACs) as therapeutic target for depressive disorders. HDAC, HDACs, MDD
92  2018 Induction of Kruppel-like factor 2 reduces K/BxN serum-induced arthritis. KLF2, RA
93  2018 MC1568 Enhances Histone Acetylation During Oocyte Meiosis and Improves Development of Somatic Cell Nuclear Transfer Embryos in Pig. HDAC, SCNT
94  2018 Preclinical Studies Support Combined Inhibition of BET Family Proteins and Histone Deacetylases as Epigenetic Therapy for Cutaneous T-Cell Lymphoma. BETi, CTCL
95  2018 Radiosensitivity enhancement of human thyroid carcinoma cells by the inhibitors of histone deacetylase sodium butyrate and valproic acid. ---
96  2018 Tat controls transcriptional persistence of unintegrated HIV genome in primary human macrophages. uDNA, uTat
97  2018 Zinc Dependent Histone Deacetylase Inhibitors in Cancer Therapeutics: Recent Update. HDAC, ROS
98  2017 Acetazolamide potentiates the anti-tumor potential of HDACi, MS-275, in neuroblastoma. AZ, CAs, CSC, HDACs, NB
99  2017 Administration of a Histone Deacetylase Inhibitor into the Basolateral Amygdala Enhances Memory Consolidation, Delays Extinction, and Increases Hippocampal BDNF Levels. BLA, HDACs, IA, TSA
100  2017 HDAC Inhibitors Disrupt Programmed Resistance to Apoptosis During Drosophila Development. HDACs