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■ Abbreviation / Long Form : HRP / handle region peptide

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Total Number of Papers: 31
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Abbreviation:   HRP  (>> Co-occurring Abbreviation)
Long Form:   handle region peptide
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No. Year Title Co-occurring Abbreviation
2019 (Pro)renin Receptor Blockade Ameliorates Heart Failure Caused by Chronic Kidney Disease. Ang, CKD
2019 Aortic constriction induces hypertension and cardiac hypertrophy via (pro)renin receptor activation and the PLC‑beta3 signaling pathway. Ang, ERK, PKC, PLC
2017 Inhibition of (pro)renin Receptor Contributes to Renoprotective Effects of Angiotensin II Type 1 Receptor Blockade in Diabetic Nephropathy. Ang II, DN, MCs, MMP-2, RAS, STZ, TGF-beta1
2017 Shenfuqiangxin Capsule inhibits apoptosis through mitogen-activated protein kinase signal pathway in rats with cardio-renal syndrome induced by infrarenal aortic-clamping. CRS, MAPK, p-JNK, p-p38, RT-PCR
2016 Prorenin/renin receptor blockade promotes a healthy fat distribution in obese mice. HF/HC, SCF, VAT
2015 Different effect of handle region peptide on beta-cell function in different sexes of rats neonatally treated with sodium L-glutamate. ---
2015 The Role of the (Pro)renin Receptor in Hypertensive Disease. DOCA
2014 (Pro)renin receptor in skeletal muscle is involved in the development of insulin resistance associated with postinfarct heart failure in mice. HF, MI
2014 Combined renin inhibition/(pro)renin receptor blockade in diabetic retinopathy--a study in transgenic (mREN2)27 rats. DR, RAS, STZ
10  2014 Deterioration of kidney function by the (pro)renin receptor blocker handle region peptide in aliskiren-treated diabetic transgenic (mRen2)27 rats. RAS
11  2014 Impact of the prorenin/renin receptor on the development of obesity and associated cardiometabolic risk factors. ---
12  2013 Handle Region Peptide Ameliorating Insulin Resistance but Not beta Cell Functions in Male Rats Neonatally Treated with Sodium L-Glutamate. MSG
13  2013 The (pro)renin receptor blocker handle region peptide upregulates endothelium-derived contractile factors in aliskiren-treated diabetic transgenic (mREN2)27 rats. ETA, NOS, RAS
14  2012 (Pro)renin and its receptors: pathophysiological implications. pro
15  2012 Hemodynamic, hormonal, and renal effects of (pro)renin receptor blockade in experimental heart failure. HF
16  2012 Up-regulation of TGF-beta via the activation of extracellular signal-regulated kinase 1 and 2 induced by prorenin in human renal mesangial cells. HRMCs
17  2011 Handle region peptide counteracts the beneficial effects of the Renin inhibitor aliskiren in spontaneously hypertensive rats. MAP
18  2011 Involvement of activated prorenin in the pathogenesis of slowly progressive nephropathy in the non-clipped kidney of two kidney, one-clip hypertension. GI, TD, TGF
19  2011 Renal (pro)renin receptor contributes to development of diabetic kidney disease through transforming growth factor-beta1-connective tissue growth factor signalling cascade. CTGF, RMC, STZ, TGF-beta1
20  2010 Add-on blockade of (pro)renin receptor in imidapril-treated diabetic SHRsp. ---
21  2010 RILLKKMPSV influences the vasculature, neurons and glia, and (pro)renin receptor expression in the retina. OIR
22  2009 Inhibition of renin/prorenin receptor attenuated mesangial cell proliferation and reduced associated fibrotic factor release. siRNA, TGF-beta1
23  2009 Renin, prorenin and the kidney: a new chapter in an old saga. ---
24  2008 (Pro)renin receptor peptide inhibitor "handle-region" peptide does not affect hypertensive nephrosclerosis in Goldblatt rats. 2K1C
25  2008 Physiology and pharmacology of the (pro)renin receptor. ---
26  2008 Prorenin and renin-induced extracellular signal-regulated kinase 1/2 activation in monocytes is not blocked by aliskiren or the handle-region peptide. ERK
27  2008 Renin receptor blockade: a better strategy for renal protection than renin-angiotensin system inhibition? ---
28  2008 Role of prorenin in the pathogenesis of retinal neovascularization. Ang-2, Flk-1, Flt-1, VEGF
29  2007 Role of nonproteolytically activated prorenin in pathologic, but not physiologic, retinal neovascularization. ICAM, RAS, VEGF, VEGFR
30  2007 [Expression of renin/prorenin receptor in rat kidney and cultured mesangial cells]. FITC-HRP, MCs, RnR
31  2006 Suppression of ocular inflammation in endotoxin-induced uveitis by inhibiting nonproteolytic activation of prorenin. CCL, EIU, ICAM, IL, LPS, MCP, RAS