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■ Abbreviation / Long Form : IBMX / 3-isobutyl-1-methylxanthine

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Abbreviation:   IBMX  (>> Co-occurring Abbreviation)
Long Form:   3-isobutyl-1-methylxanthine
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No. Year Title Co-occurring Abbreviation
2022 Anesthetics and Cell-Cell Communication: Potential Ca2+-Calmodulin Role in Gap Junction Channel Gating by Heptanol, Halothane and Isoflurane. ---
2022 Antidiabetic Actions of Ethanol Extract of Camellia sinensis Leaf Ameliorates Insulin Secretion, Inhibits the DPP-IV Enzyme, Improves Glucose Tolerance, and Increases Active GLP-1 (7-36) Levels in High-Fat-Diet-Fed Rats. DPP-IV, EECS, GLP-1
2022 Changes in cAMP signaling are associated with age-related downregulation of spontaneously beating atrial tissue energetic indices. ---
2022 Increase in Ca2+-Activated cAMP/PKA Signaling Prevents Hydroxychloroquine-Induced Bradycardia of the Cardiac Pacemaker. HCQ, hiPSC-CMs, SAN
2022 Insulin Secretory Actions of Ethanol Extract of Eucalyptus citriodora Leaf, including Plasma DPP-IV and GLP-1 Levels in High-Fat-Fed Rats, as Well as Characterization of Biologically Effective Phytoconstituents. EEEC, GLP-1, HFF
2022 Insulin secretory and antidiabetic actions of Heritiera fomes bark together with isolation of active phytomolecules. H. fomes, HWHF
2022 Oxalate secretion is stimulated by a cAMP-dependent pathway in the mouse cecum. CFTR, FSK, KO, PAT1
2022 Polyphenol-Rich Leaf of Annona squamosa Stimulates Insulin Release from BRIN-BD11 Cells and Isolated Mouse Islets, Reduces (CH2O)n Digestion and Absorption, and Improves Glucose Tolerance and GLP-1 (7-36) Levels in High-Fat-Fed Rats. CVD, HFF
2022 Promoting Immortalized Adipose-Derived Stem Cell Transdifferentiation and Proliferation into Neuronal-Like Cells through Consecutive 525 nm and 825 nm Photobiomodulation. ADSCs, BHA, BME, CNTF, ELISAs, IT1, NIR, NSE, PBM
10  2022 Sorghum (Sorghum bicolor) Extract-Induced Adipogenesis Is Independent of PPARγ Ser273 Phosphorylation in 3T3-L1 Adipocytes. aP2, PPARalpha, PPARgamma, SE, TRO, TZD
11  2022 The combination of nuclear receptor NR1D1 and ULK1 promotes mitophagy in adipocytes to ameliorate obesity. ATCC, ChIP, DEX, ELISA, FBS, IF, mtROS, mut, NR1D1, qRT-PCR, SD, sh-ULK1, TG, ULK1, WT
12  2022 Tyrosinase suppresses vasculogenic mimicry in human melanoma cells. alpha-MSH, KO, TYR, VM
13  2022 α Cell dysfunction in islets from nondiabetic, glutamic acid decarboxylase autoantibody-positive individuals. AAbs, GADA, PKIB, T1D
14  2021 alpha-Poly-L-lysine functions as an adipogenic inducer in 3T3-L1 preadipocytes. DEX, MW, PLL
15  2021 cAMP Modulators before In Vitro Maturation Decrease DNA Damage and Boost Developmental Potential of Sheep Oocytes. ---
16  2021 Characterisation of ovine bone marrow-derived stromal cells (oBMSC) and evaluation of chondrogenically induced micro-pellets for cartilage tissue repair in vivo. BMSC, oACh, oBMSC, oBMSC
17  2021 Characterization of the cAMP phosphodiesterase domain in plant adenylyl cyclase/cAMP phosphodiesterase CAPE from the liverwort Marchantia polymorpha. AC, cAMP, PDE
18  2021 Effect of selected natural and synthetic substances on rabbit reproduction-A mini review. cAMP, CL, GT, YS
19  2021 Endocytic protein Pal1 regulates appressorium formation and is required for full virulence of Magnaporthe oryzae. ---
20  2021 Environmental obesogens (bisphenols, phthalates and parabens) and their impacts on adipogenic transcription factors in the absence of dexamethasone in 3T3-L1 cells. BPA, DEX, EDCs
21  2021 Functional modulation of phosphodiesterase-6 by calcium in mouse rod photoreceptors. GCAPs, PDE6
22  2021 Identification of Multiple Pancreatic and Extra-Pancreatic Pathways Underlying the Glucose-Lowering Actions of Acacia arabica Bark in Type-2 Diabetes and Isolation of Active Phytoconstituents. DPP-IV, HFF, HWAA
23  2021 Induction of Adipogenic Genes by Novel Serum-Free Conditions From Pre-adipocyte 3T3-L1 and ST2 Cells. BSA, DMEM, FBS, FFA, ITS, NIH, PPARgamma, RPMI, RT-PCR
24  2021 Nisin and non-essential amino acids: new perspective in differentiation of neural progenitors from human-induced pluripotent stem cells in vitro. AO, hiPSCs, ICC, NEAA, NI
25  2021 Novel Facet of an Old Dietary Molecule? Direct Influence of Caffeine on Glucose and Biogenic Amine Handling by Human Adipocytes. 2-DG, PrAO
26  2021 Research Note: Adipogenic differentiation of embryonic fibroblasts of chicken, turkey, duck, and quail in vitro by medium containing chicken serum alone. CEF, CS, FBS, TAG
27  2021 Selenium enhances the expression of miR-9, miR-124 and miR-29a during neural differentiation of bone marrow mesenchymal stem cells. BDNF, BMSCs, ChAT, DMEM, FGF-2, MAP-2, RT-PCR, Se
28  2021 Standardized Edible Bird's Nest Extract Prevents UVB Irradiation-Mediated Oxidative Stress and Photoaging in the Skin. UVB
29  2021 The role of NHE3 (Slc9a3) in oxalate and sodium transport by mouse intestine and regulation by cAMP. FSK, WT
30  2021 Vinpocetine alleviates lung inflammation via macrophage inflammatory protein-1beta inhibition in an ovalbumin-induced allergic asthma model. DEX, MIP-1beta, OVA, PDE
31  2020 Anti-Melanogenesis Activity of 6-O-Isobutyrylbritannilactone from Inula britannica on B16F10 Melanocytes and In Vivo Zebrafish Models. IBL, MITF, PI3K
32  2020 Anti-Melanogenic Effect of Ethanolic Extract of Sorghum bicolor on IBMX-Induced Melanogenesis in B16/F10 Melanoma Cells. 9-HODE, ABTS, DPPH, ESB, L-DOPA, MDA, MITF, S. bicolor, TPC, TRP
33  2020 Combined use of dbcAMP and IBMX minimizes the damage induced by a long-term artificial meiotic arrest in mouse germinal vesicle oocytes. cAMP, CLZ, dbcAMP, GV, MIL, PDE
34  2020 Cryptochrome 1 Alleviates the Antiproliferative Effect of Isoproterenol on Human Gastric Cancer Cells. AC, CRY1, FSK, ISO, PDE
35  2020 Evaluation of the Antidiabetic and Insulin Releasing Effects of A. squamosa, Including Isolation and Characterization of Active Phytochemicals. HWAS
36  2020 Influence of Phosphodiesterase Inhibition on CRE- and EGR1-Dependent Transcription in a Mouse Hippocampal Cell Line. CREB, EGR1, FGF, PDE, PKA
37  2020 Inhibition of germinal vesicle breakdown using IBMX increases microRNA-21 in the porcine oocyte. GVBD, MIR21, miRNA, PDCD4, PTGR
38  2020 Intrauterine growth restriction is associated with sex-specific alterations in the nitric oxide/cyclic GMP relaxing pathway in the human umbilical vein. AGA, cGMP, IUGR, NO, PDEs, sGC, UV
39  2020 Methylxanthines Inhibit Primary Amine Oxidase and Monoamine Oxidase Activities of Human Adipose Tissue. hScAT, MAO, PrAO
40  2020 Molecular Mechanisms Involved in Neural Substructure Development during Phosphodiesterase Inhibitor Treatment of Mesenchymal Stem Cells. CDK5, MAPK, MSC, PI3K
41  2020 Na+-K+-2Cl- cotransporter 2 located in the human and murine gastric mucosa is involved in secretagogue-induced gastric acid secretion and is downregulated in lipopolysaccharide-treated mice. LPS, NKCC, VAMP2
42  2020 Protein kinase A negatively regulates VEGF-induced AMPK activation by phosphorylating CaMKK2 at serine 495. ACC, AMPK, CaMKK2, PKA, VEGF
43  2020 The bitter taste receptor agonist-induced negative chronotropic effects on the Langendorff-perfused isolated rat hearts. PDEs, SA
44  2020 The Phosphodiesterase Inhibitor IBMX Blocks the Potassium Channel THIK-1 from the Extracellular Side. PKA
45  2020 The Phosphodiesterase Inhibitor, Isobutyl-1-Methylxanthine Prevents the Sudden Drop in Cyclic Adenosine Monophosphate Concentration and Modulates Glucose Metabolism of Equine Cumulus-Oocyte Complexes Matured inVitro. cAMP, COCs, IVM
46  2019 125 Iodide as a surrogate tracer for epithelial chloride transport by the mouse large intestine in vitro. FSK
47  2019 Adipogenesis induces growth inhibition of dedifferentiated liposarcoma. DDLPS, WDLPS
48  2019 Anti-melanin deposition activity and active constituents of Jatropha multifida stems. alpha-MSH
49  2019 Effect of pre-maturation with C-type natriuretic peptide and 3-isobutyl-1-methylxanthine on cumulus-oocyte communication and oocyte developmental competence in cattle. CNP, GV
50  2019 Effect of the Stromal Vascular Fraction on Changes in Melanin Formation in B16 Cells Treated by IBMX. SVF
51  2019 Effect of the TYK-2/STAT-3 pathway on lipid accumulation induced by mono-2-ethylhexyl phthalate. DEX, MEHP, qPCR, ROS
52  2019 Pharmacological and molecular dynamics analyses of differences in inhibitor binding to human and nematode PDE4: Implications for management of parasitic nematodes. MD, PDE
53  2019 Which phosphodiesterase can decrease cardiac effects of 5-HT4 receptor activation in transgenic mice? cAMP, EHNA, PDEs, Tg, WT
54  2018 A comparison of methods for effective differentiation of the frozen-thawed 3T3-L1 cells. DEX
55  2018 A novel synthetic compound, (Z)-5-(3-hydroxy-4-methoxybenzylidene)-2-iminothiazolidin-4-one (MHY773) inhibits mushroom tyrosinase. alpha-MSH
56  2018 Anti-melanogenesis potential of a new series of Morita-Baylis-Hillman adducts in B16F10 melanoma cell line. MBH
57  2018 Calcium: A novel and efficient inducer of differentiation of adipose-derived stem cells into neuron-like cells. ADSCs, GFAP, MAP2, MBP, NeuN, NSE, qRT-PCR
58  2018 cAMP/Protein Kinase A Signaling Inhibits Dlx5 Expression via Activation of CREB and Subsequent C/EBPbeta Induction in 3T3-L1 Preadipocytes. CREB, Dlx5, PKA
59  2018 Cyclic AMP Signaling Promotes the Differentiation of Human Induced Pluripotent Stem Cells into Intestinal Epithelial Cells. 8-Br-cAMP, cAMP, iPS
60  2018 Dual Activation of Phosphodiesterases 3 and 4 Regulates Basal Spontaneous Beating Rate of Cardiac Pacemaker Cells: Role of Compartmentalization? AP, cAMP, DD, PDEs, PKA, RyR, SA
61  2018 Effect of pre-in vitro maturation with cAMP modulators on the acquisition of oocyte developmental competence in cattle. AREG, DBcAMP, EGF, FSH, IVM
62  2018 Effects of pre-maturational culture duration on developmental competence of bovine small-sized oocytes. ---
63  2018 Electrophysiological determination of phosphodiesterase-6 inhibitor inhibition constants in intact mouse retina. PDEs
64  2018 Fsk and IBMX inhibit proliferation and proapoptotic of glioma stem cells via activation of cAMP signaling pathway. FSK, GSCs
65  2018 Influence of Biochemical Cues in Human Corneal Stromal Cell Phenotype. AA, ALDH3A1, FGF-2, IGF-1, ITS, RA, TGF-beta1
66  2018 Inhibition of PDE3A sustains meiotic arrest and gap junction of bovine growing oocytes in invitro growth culture. OCCs, PDE
67  2018 Linderane Suppresses Hepatic Gluconeogenesis by Inhibiting the cAMP/PKA/CREB Pathway Through Indirect Activation of PDE 3 via ERK/STAT3. cAMP, CREB, G6PC, PDE3, STAT3
68  2018 Natalenamides A⁻C, Cyclic Tripeptides from the Termite-Associated Actinomadura sp. RB99. HRESIMS, LC, MS, NMR, UV
69  2018 Treatment with cyclic adenosine monophosphate modulators prior to in vitro maturation alters the lipid composition and transcript profile of bovine cumulus-oocyte complexes and blastocysts. COCs, FSK
70  2018 Triphala, Regulates Adipogenesis through Modulation of Expression of Adipogenic Genes in 3T3-L1 Cell Line. DEX
71  2018 Voltage-dependent inward currents in smooth muscle cells of skeletal muscle arterioles. ---
72  2017 Cyclic AMP reverses the effects of aging on pacemaker activity and If in sinoatrial node myocytes. AP, cAMP, MHR, SAMs
73  2017 Dynamic monitoring of Gi/o-protein-mediated decreases of intracellular cAMP by FRET-based Epac sensors. FRET, GPCR
74  2017 Effects of chlorogenic acid on carbachol-induced contraction of mouse urinary bladder. cAMP, CCh, CGA, PDE
75  2017 Embryonic cholesterol esterification is regulated by a cyclic AMP-dependent pathway in yolk sac membrane-derived endodermal epithelial cells. EECs, PKA, SOAT
76  2017 Evaluation of human dermal fibroblasts directly reprogrammed to adipocyte-like cells as a metabolic disease model. ---
77  2017 IBMX protects human proximal tubular epithelial cells from hypoxic stress through suppressing hypoxia-inducible factor-1alpha expression. cAMP, HIF-1alpha, PDE, PKA
78  2017 Methylxanthines induce structural and functional alterations of the cardiac system in zebrafish embryos. ---
79  2017 Resveratrol enhances the inotropic effect but inhibits the proarrhythmic effect of sympathomimetic agents in rat myocardium. PDE
80  2017 Sperm capacitation pretreatment positively impacts bovine intracytoplasmic sperm injection. ICSI, MbetaCD
81  2017 The beta3 -adrenoceptor agonist mirabegron increases human atrial force through beta1 -adrenoceptors: an indirect mechanism? ---
82  2016 A proline-type fullerene derivative inhibits adipogenesis by preventing PPARgamma activation. ---
83  2016 Aged Garlic Extract Inhibits Human Platelet Aggregation by Altering Intracellular Signaling and Platelet Shape Change. AC, AGE, cGMP, sGC
84  2016 Anti-melanin deposition activity of ceramicines from Chisocheton ceramicus. alpha-MSH
85  2016 Cardiac mesenchymal progenitors differentiate into adipocytes via Klf4 and c-Myc. CMPs, PPAR, TFs
86  2016 Cocktail supplement with rosiglitazone: a novel inducer for chicken preadipocyte differentiation invitro. DEX, G0S2, GPDH, INS, PPAR
87  2016 Communication of cAMP by connexin43 gap junctions regulates osteoblast signaling and gene expression. CRE-luc, Cx43, PGE2, RANKL
88  2016 Extending prematuration with cAMP modulators enhances the cumulus contribution to oocyte antioxidant defence and oocyte quality via gap junctions. BSO, cAMP, CBX, CSC, FSK, GJC, IVM, STARR
89  2016 Fat accumulation in differentiated brown adipocytes is linked with expression of Hox genes. BAT, DEX, HOX, SVF, WAT
90  2016 Glucocorticoids Alter CRTC-CREB Signaling in Muscle Cells: Impact on PGC-1alpha Expression and Atrophy Markers. CNA, PGC-1alpha-Luc
91  2016 Induction of CCAAT/Enhancer-Binding Protein beta Expression With the Phosphodiesterase Inhibitor Isobutylmethylxanthine Improves Myoblast Engraftment Into Dystrophic Muscle. DMD
92  2016 Involvement of cAMP in the Human Serum-Induced Migration of Adipose-Derived Stem Cells. FBS, hADSCs, HS
93  2016 Obox4-silencing-activated STAT3 and MPF/MAPK signaling accelerate nuclear membrane breakdown in mouse oocytes. GV, GVBD, IFNA, MPF, Obox4, RNAi, STAT3
94  2016 Phospholamban degradation is induced by phosphorylation-mediated ubiquitination and inhibited by interaction with cardiac type Sarco(endo)plasmic reticulum Ca(2+)-ATPase. ISO, PKA, PLN
95  2016 PLD1 regulates adipogenic differentiation through mTOR - IRS-1 phosphorylation at serine 636/639. DEPTOR, HFD, IRS-1, PA, PLD1
96  2016 Pretreatment of cultured preadipocytes with arachidonic acid during the differentiation phase without a cAMP-elevating agent enhances fat storage after the maturation phase. AA, COX, PG
97  2016 Prolonged treatment with 3-isobutyl-1-methylxanthine improves the efficiency of differentiating 3T3-L1 cells into adipocytes. ---
98  2016 PTB and TIAR binding to insulin mRNA 3'- and 5'UTRs; implications for insulin biosynthesis and messenger stability. hnRNP, PTB, RBPs, UTRs
99  2016 Rapid Induction of Neural Differentiation in Human Umbilical Cord Matrix Mesenchymal Stem Cells by cAMP-elevating Agents. GFAP, hUCM, MAP-2, MSCs, NSE
100  2016 Serotonin (5-HT) and 5-HT2A receptor agonists suppress lipolysis in primary rat adipose cells. PKA