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■ Abbreviation / Long Form : IGF1R / insulin-like growth factor 1 receptor

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Total Number of Papers: 465
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Abbreviation:   IGF1R  (>> Co-occurring Abbreviation)
Long Form:   insulin-like growth factor 1 receptor
 Abbreviation Variation
 Long Form Variation
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No. Year Title Co-occurring Abbreviation
2019 A multi-targeted probe-based strategy to identify signaling vulnerabilities in cancers. INSR, NSCLC
2019 Benzyl isothiocyanate suppresses IGF1R, FGFR3 and mTOR expression by upregulation of miR-99a-5p in human bladder cancer cells. BC, BITC, FGFR3, mTOR, qPCR, RT
2019 beta-Pentagalloyl-Glucose Sabotages Pancreatic Cancer Cells and Ameliorates Cachexia in Tumor-Bearing Mice. HIF-1, IR
2019 Calycosin stimulates the osteogenic differentiation of rat calvarial osteoblasts by activating the IGF1R/PI3K/Akt signaling pathway. ALP, ALPL, BMP2, ROBs
2019 Cancer Vaccines Co-Targeting HER2/Neu and IGF1R. HER2, RTKs
2019 CuS Nanoparticles as a Photodynamic Nanoswitch for Abrogating Bypass Signaling To Overcome Gefitinib Resistance. NPs, ROS
2019 Decreased Amino Acid Concentrations are Involved in Congenital Heart Disease. AAs, AF, CHD
2019 Expression of PAPP-A2 and IGF Pathway-Related Proteins in the Hip Joint of Normal Rat and Those with Developmental Dysplasia of the Hip. DDH, IGF, IGFBP-5, PAPP-A2
2019 Ginsenoside F1 promotes angiogenesis by activating the IGF-1/IGF1R pathway. CAM, GF1, IGF-1, MCAO, MVD
10  2019 High Glucose Concentrations Negatively Regulate the IGF1R/Src/ERK Axis through the MicroRNA-9 in Colorectal Cancer. CRC, EMT, HG, miR-9
11  2019 Identification of Differentially Expressed Genes and Long Noncoding RNAs Associated with Parkinson's Disease. ceRNA, DEGs, DElncRNAs, GO, lncRNAs, PD
12  2019 Identification of nucleolar protein NOM1 as a novel nuclear IGF1R-interacting protein. MIF4G
13  2019 IGF1R as druggable target mediating PI3K-delta inhibitor resistance in a murine model of chronic lymphocytic leukemia. FOXO1, GSK3B
14  2019 Immune targeting of autocrine IGF2 hampers rhabdomyosarcoma growth and metastasis. ---
15  2019 Improvement of growth performance and parameters of intestinal function in liquid fed early weanling pigs. ATTD, CLDN2, ZO-1, ZO-2
16  2019 Insulin-like growth factor-1 receptor expression in upper tract urothelial carcinoma. CI, HR, TMAs, UTUC
17  2019 Knockdown of PSMC3IP suppresses the proliferation and xenografted tumorigenesis of hepatocellular carcinoma cell. eIF4E, HCC, PSMC3IP
18  2019 Let-7b acts as a tumor suppressor in osteosarcoma via targeting IGF1R. OS
19  2019 MicroRNA‑98 suppresses cell growth and invasion of retinoblastoma via targeting the IGF1R/k‑Ras/Raf/MEK/ERK signaling pathway. miRNAs, Rb
20  2019 Persistent endocrine-disrupting chemicals found in human follicular fluid stimulate the proliferation of granulosa tumor spheroids via GPR30 and IGF1R but not via the classic estrogen receptors. ESR1, ESR2, GCT, HCB, PCB153, PFOA, PFOS
21  2019 Phase II Study of Everolimus and Octreotide LAR in Patients with Nonfunctioning Gastrointestinal Neuroendocrine Tumors: The GETNE1003_EVERLAR Study. AEs, CI, GI-NETs, mTOR, NETs, ORR, OS, PFS, pS6, SSAs
22  2019 Possible mechanisms of prenatal cold stress induced-anxiety-like behavior depression in offspring rats. BDNF, CRHR1, DA, GABAB2, GFAP, GR, HPA, MR, NE, NeuN
23  2019 Role of miR-16-5p in the proliferation and metastasis of hepatocellular carcinoma. EMT, HCC, qRT-PCR, WB
24  2019 Sterol structure dependence of insulin receptor and insulin-like growth factor 1 receptor activation. IR
25  2019 Survivin in Insulin-Like Growth Factor-Induced Resistance to Lapatinib in Head and Neck Squamous Carcinoma Cells. EGFR, HNSCC, TKIs
26  2019 Targeting the insulin-like growth factor-1 receptor in MTAP-deficient renal cell carcinoma. MTA, MTAP, RCC
27  2019 Two prostate cancer‑associated polymorphisms in the 3'UTR of IGF1R influences prostate cancer susceptibility by affecting miRNA binding. mi, PCa, SNPs
28  2018 Ablation of insulin receptor substrates 1 and 2 suppresses Kras-driven lung tumorigenesis. IR, KRAS, NSCLC
29  2018 Activated receptor tyrosine kinases in granulosa cells of ovulating follicles in mice. eCG, EPHB1, FGF-2, FGFR2, hCG, LH, RTKs
30  2018 Analysis of genetic polymorphisms associated with intervertebral disc degeneration. IVDD, MMP2, VDR
31  2018 Anthricin‑induced caspase‑dependent apoptosis through IGF1R/PI3K/AKT pathway inhibition in A549 human non‑small lung cancer cells. ---
32  2018 Antitumor effects of beta-elemene via targeting the phosphorylation of insulin receptor. ESFTs, IR
33  2018 Characterization of an activating R1353H insulin-like growth factor 1 receptor variant in a male with extreme tall height. AR
34  2018 Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis. MS, TGFBR1, Treg
35  2018 Circulating microRNA-99 family as liquid biopsy marker in pancreatic adenocarcinoma. PDAC, ROC
36  2018 CKS1BP7, a Pseudogene of CKS1B, is Co-Amplified with IGF1R in Breast Cancers. CKS1B, CKS1BP7, CNAs, DCIS, QM-FISH
37  2018 Coffee Is Associated With Lower Breast Tumor Insulin-Like Growth Factor Receptor 1 Levels in Normal-Weight Patients and Improved Prognosis Following Tamoxifen or Radiotherapy Treatment. BMI, HR
38  2018 Controlled dimerization of insulin-like growth factor-1 and insulin receptors reveals shared and distinct activities of holo and hybrid receptors. HybRs, INSR
39  2018 Effect of acute stressors, adrenocorticotropic hormone administration, and cortisol release on milk yield, the expression of key genes, proliferation, and apoptosis in goat mammary epithelial cells. ACTH, GHR, IGF1
40  2018 Evidence for Compromised Insulin Signaling and Neuronal Vulnerability in Experimental Model of Sporadic Alzheimer's Disease. APP, i.c.v, IGF2, IR, IRS2, p-GSK3betaser9, SAD, STZ, t-GSK3beta
41  2018 Function of insulin-like growth factor 1 receptor in cancer resistance to chemotherapy. ---
42  2018 Genome-Wide Analyses Identify Filamin-A As a Novel Downstream Target for Insulin and IGF1 Action. FLNA
43  2018 Genomewide DNA Methylation Responses in Patients with beta-Thalassemia Treated with Yisui Shengxue Granules (). Hb, JAK3, MAPK10, RBCs, RET
44  2018 Identification and functional analysis of a novel G310D variant in the insulin-like growth factor 1 receptor (IGF1R) gene associated with type 2 diabetes in American Indians. OR, T2D
45  2018 Identifying Involvement of H19-miR-675-3p-IGF1R and H19-miR-200a-PDCD4 in Treating Pulmonary Hypertension with Melatonin. LV, MCT, PAH, PDCD4, RV, sPAP
46  2018 IDH1R132H Promotes Malignant Transformation of Benign Prostatic Epithelium by Dysregulating MicroRNAs: Involvement of IGF1R-AKT/STAT3 Signaling Pathway. IDH, PCa
47  2018 IGF1R signaling drives antiestrogen resistance through PAK2/PIX activation in luminal breast cancer. ---
48  2018 IGF1R signalling in testicular germ cell tumour cells impacts on cell survival and acquired cisplatin resistance. TGCTs
49  2018 IGF1R upregulation confers resistance to isoform-specific inhibitors of PI3K in PIK3CA-driven ovarian cancer. GA, OC, PI3K
50  2018 Inflammation in the hippocampus affects IGF1 receptor signaling and contributes to neurological sequelae in rheumatoid arthritis. IRS-1, RA
51  2018 Inhibition of insulin-like growth factor 1 receptor enhances the efficacy of sorafenib in inhibiting hepatocellular carcinoma cell growth and survival. HCC, VEGFR
52  2018 Insulin induces an EMT-like process in mammary epithelial cells MCF10A. EMT
53  2018 Insulin-like growth factor 1 receptor signaling regulates embryonic epicardial cell proliferation through focal adhesion kinase pathway. EPCs
54  2018 Insulin-like growth factor 1 receptor stabilizes the ETV6-NTRK3 chimeric oncoprotein by blocking its KPC1/Rnf123-mediated proteasomal degradation. ETV6, INSR, SILAC
55  2018 IRS2 mutations linked to invasion in pleomorphic invasive lobular carcinoma. IR, IRS2, PILC
56  2018 Let-7c inhibits migration and epithelial-mesenchymal transition in head and neck squamous cell carcinoma by targeting IGF1R and HMGA2. EMT, HMGA2, HNSCC
57  2018 Lnc-SNHG1 may promote the progression of non-small cell lung cancer by acting as a sponge of miR-497. NSCLC
58  2018 Long noncoding RNA PVT1 enhances the viability and invasion of papillary thyroid carcinoma cells by functioning as ceRNA of microRNA-30a through mediating expression of insulin like growth factor 1 receptor. EMT, miR-30a, PTC
59  2018 Loss of IGF1R in Human Astrocytes Alters Complex I Activity and Support for Neurons. IGF1, LUHMES
60  2018 MicroRNA-495 suppresses cell proliferation and invasion of hepatocellular carcinoma by directly targeting insulin-like growth factor receptor-1. HCC, TNM
61  2018 MicroRNA-Dependent Regulation of IGF1R Gene Expression in Hormone-Sensitive and Hormone-Resistant Prostate Cancer Cells. ---
62  2018 miR-100 inhibits the migration and invasion of nasopharyngeal carcinoma by targeting IGF1R. NPC, RT-qPCR
63  2018 MiR-30a-5p confers cisplatin resistance by regulating IGF1R expression in melanoma cells. miRNAs
64  2018 miRNA-376c-3p Mediates TWIST-1 Inhibition of Bone Marrow-Derived Stromal Cell Osteogenesis and Can Reduce Aberrant Bone Formation of TWIST-1 Haploinsufficient Calvarial Cells. ALP, BMSC, miRNAs, TWIST1
65  2018 Modulation of IGF1R Signaling Pathway by GIGYF1 in High Glucose-Induced SHSY-5Y Cells. AKT, ERK
66  2018 Nuclear translocation of IGF1R by intracellular amphiregulin contributes to the resistance of lung tumour cells to EGFR-TKI. EGFR-TKI
67  2018 Oncogenic fusion proteins adopt the insulin-like growth factor signaling pathway. ---
68  2018 POU2F3 is a master regulator of a tuft cell-like variant of small cell lung cancer. SCLC, TF
69  2018 Protegrin 1 Enhances Innate Cellular Defense via the Insulin-Like Growth Factor 1 Receptor Pathway. AMPs
70  2018 Role of Insulin-like Growth Factor 1 Receptor Signaling in Stem Cell Stemness and Therapeutic Efficacy. ---
71  2018 Role of RBP2-Induced ER and IGF1R-ErbB Signaling in Tamoxifen Resistance in Breast Cancer. ER, RBP2, SRB
72  2018 RUNX1 promotes cell growth in human T-cell acute lymphoblastic leukemia by transcriptional regulation of key target genes. T-ALL
73  2018 SM22alpha (Smooth Muscle Protein 22-alpha) Promoter-Driven IGF1R (Insulin-Like Growth Factor 1 Receptor) Deficiency Promotes Atherosclerosis. IGF-1, SMC
74  2018 Suppression of cleavage factor Im 25 promotes the proliferation of lung cancer cells through alternative polyadenylation. APA, CCND1, CFIm25, dPAS, NSCLC
75  2018 Tanshinone IIA can inhibit MiaPaCa‑2 human pancreatic cancer cells by dual blockade of the Ras/Raf/MEK/ERK and PI3K/AKT/mTOR pathways. EGFR, ERK, MEK, mTOR, PI3K, PTEN, VEGFR
76  2018 Targeted Therapy-based Combination Treatment in Rhabdomyosarcoma. ERMS
77  2018 Tescalcin/c-Src/IGF1Rbeta-mediated STAT3 activation enhances cancer stemness and radioresistant properties through ALDH1. CSC, EMT, NSCLC, STAT3, TESC
78  2018 TGFbeta and IGF1R signaling activates protein kinase A through differential regulation of ezrin phosphorylation in colon cancer cells. CRC, PKA, TGF
79  2018 The association of diabetes mellitus and insulin treatment with expression of insulin-related proteins in breast tumors. INSR
80  2018 The Long Noncoding RNA 150Rik Promotes Mesangial Cell Proliferation via miR-451/IGF1R/p38 MAPK Signaling in Diabetic Nephropathy. Ago2, DN, EdU, lncRNAs, MCs, miR-451, RIP
81  2018 The proximity-labeling technique BioID identifies sorting nexin 6 as a member of the insulin-like growth factor 1 (IGF1)-IGF1 receptor pathway. IGF1, IRS-1, SHC1, SNX6
82  2018 The Role for Exosomal microRNAs in Disruption of Regulatory T Cell Homeostasis in Multiple Sclerosis. MS, TGFBR1
83  2018 Understanding the mechanism of bias signaling of the insulin-like growth factor 1 receptor: Effects of LL37 and HASF. ---
84  2018 Up-regulation of INSR/IGF1R by C-myc promotes TSCC tumorigenesis and metastasis through the NF-kappaB pathway. INSR, TSCC
85  2018 Upregulation of IGF1 by tumor-associated macrophages promotes the proliferation and migration of epithelial ovarian cancer cells. CM, EOC, IGF1, OC, TAMs
86  2017 A Comparative Study on the WCRF International/University of Bristol Methodology for Systematic Reviews of Mechanisms Underpinning Exposure-Cancer Associations. WCRF
87  2017 A novel heterozygous IGF-1 receptor mutation associated with hypoglycemia. ---
88  2017 Adverse Events and Efficacy of Cixutumumab in Phase II Clinical Trials: A systematic Review and Meta-Analysis. CR, HR, PFS
89  2017 Association of IGF1 and IGF1R gene polymorphisms with high myopia in a Han Chinese population. IGF1, OR, SNPs
90  2017 Attenuated airway hyperresponsiveness and mucus secretion in HDM-exposed Igf1r-deficient mice. AHR, BALF, HDM
91  2017 Bioinformatics analysis to identify the critical genes, microRNAs and long noncoding RNAs in melanoma. DEGs, lncRNAs, miRNA, PPI, RT-PCR
92  2017 Carbonate apatite nanoparticles carry siRNA(s) targeting growth factor receptor genes egfr1 and erbb2 to regress mouse breast tumor. EGF, EGFR1, EGFR2, GFRs, NPs, siRNAs
93  2017 Characterization of the acute inflammatory profile and resolution of airway inflammation after Igf1r-gene targeting in a murine model of HDM-induced asthma. HDM
94  2017 Chromosome 15 structural abnormalities: effect on IGF1R gene expression and function. ---
95  2017 Co-targeting PI3K, mTOR, and IGF1R with small molecule inhibitors for treating undifferentiated pleomorphic sarcoma. Akt, UPSs
96  2017 Differential expression of microRNA let-7b-5p regulates burn-induced hyperglycemia. miRNAs, TBSA
97  2017 Direct integrin binding to insulin-like growth factor-2 through the C-domain is required for insulin-like growth factor receptor type 1 (IGF1R) signaling. IGF1
98  2017 Distinct Afatinib Resistance Mechanisms Identified in Lung Adenocarcinoma Harboring an EGFR Mutation. IGFBP-3, NSCLC, TKI
99  2017 Downregulation of microRNA-100/microRNA-125b is associated with lymph node metastasis in early colorectal cancer with submucosal invasion. CRCs, miRNAs, mTOR, XIAP
100  2017 Epithelial IGF1R is dispensable for IGF2 mediated enhanced intestinal adaptation in retinoblastoma-deficient mice. IGF2, Rb, SBR