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■ Abbreviation / Long Form : IQ / 2-amino-3-methyl-imidazo(4,5-f)quinoline

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Abbreviation:   IQ  (>> Co-occurring Abbreviation)
Long Form:   2-amino-3-methyl-imidazo(4,5-f)quinoline
 Abbreviation Variation
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No. Year Title Co-occurring Abbreviation
2018 Genotoxicity of heterocyclic amines (HCAs) on freshly isolated human peripheral blood mononuclear cells (PBMC) and prevention by phenolic extracts derived from olive, olive oil and olive leaves. HCAs, PBMC, PhIP
2017 Metabolism of Foodborne Heterocyclic Aromatic Amines by Lactobacillus reuteri DSM 20016. HAA, PhIP, PhIP-M1
2016 Prebiotics and age, but not probiotics affect the transformation of 2-amino-3-methyl-3H-imidazo[4,5-f]quinoline (IQ) by fecal microbiota - An invitro study. GI, HAAs
2015 Protective activity of probiotic bacteria against 2-amino-3-methyl-3H-imidazo[4,5-f]quinoline (IQ) and 2-amino-1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridine (PhIP) - an in vitro study. FW, HAAs, PhIP
2014 beta-Glucuronidase and beta-glucosidase activity and human fecal water genotoxicity in the presence of probiotic lactobacilli and the heterocyclic aromatic amine IQ in vitro. FW
2014 The influence of Lactobacillus casei DN 114 001 on the activity of faecal enzymes and genotoxicity of faecal water in the presence of heterocyclic aromatic amines. FW, PhIP
2013 Effects of varying degrees of doneness on the formation of heterocyclic aromatic amines in chicken and beef satay. HAs, PhIP
2013 Genotoxicity and induction of DNA damage responsive genes by food-borne heterocyclic aromatic amines in human hepatoma HepG2 cells. HAAs, PhIP
2012 Photodegradation of environmental mutagens by visible irradiation in the presence of xanthene dyes as photosensitizers. DEAE, DMPO
10  2011 Antioxidant and antigenotoxic effects of rosemary (Rosmarinus officinalis L.) extracts in Salmonella typhimurium TA98 and HepG2 cells. BaP, NQNO, PhIP, t-BOOH
11  2011 [Simultaneous determination of 9 heterocyclic aromatic amine in poultry products by solid-phase extraction-high performance liquid chromatography]. HAAs, PRS, RSDs, SPE, SPE-HPLC
12  2010 Antimutagenic effects of lycopene and tomato puree. MNU
13  2010 Effect of rapid human N-acetyltransferase 2 haplotype on DNA damage and mutagenesis induced by 2-amino-3-methylimidazo-[4,5-f]quinoline (IQ) and 2-amino-3,8-dimethylimidazo-[4,5-f]quinoxaline (MeIQx). CHO, CYP1A2, dG, HPRT, NAT2
14  2010 Xanthohumol, a prenylated flavonoid contained in beer, prevents the induction of preneoplastic lesions and DNA damage in liver and colon induced by the heterocyclic aromatic amine amino-3-methyl-imidazo[4,5-f]quinoline (IQ). XN
15  2008 Protective effects of epigallocatechin gallate on colon preneoplastic lesions induced by 2-amino-3-methylimidazo[4,5-f ] quinoline in mice. ACF, EGCG, IHC, Nrf2, UGT
16  2007 Increased susceptibility to hepatocarcinogenicity of Nrf2-deficient mice exposed to 2-amino-3-methylimidazo[4,5-f]quinoline. Nrf2
17  2005 Characterization of antimutagenic mechanism of 3-allyl-5-substituted 2-thiohydantoins against 2-amino-3-methylimidazo[4,5-f]quinoline. CYP1A, EROD
18  2005 Peroxidase-like catalytic activity of anion-exchange resins modified with metal-porphyrins in oxidative reaction of hetrocyclic amines with hydrogen peroxide. HCAs, POD
19  2004 Anti-genotoxic activity of the mushroom Lactarius vellereus extract in bacteria and in mammalian cells in vitro. 4NQO
20  2004 Antimutagenic activity of spearmint. NPD
21  2004 Effect of common Brassica vegetables (Brussels sprouts and red cabbage) on the development of preneoplastic lesions induced by 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) in liver and colon of Fischer 344 rats. ---
22  2004 Effect of intestinal microfloras from vegetarians and meat eaters on the genotoxicity of 2-amino-3-methylimidazo[4,5-f]quinoline, a carcinogenic heterocyclic amine. ---
23  2004 Uptake of heterocyclic aromatic amine by insoluble dietary fiber in artificial gastric and intestinal juice. AGJ, AIJ, CMC, DF, HAA
24  2003 Dietary low-dose sucrose modulation of IQ-induced genotoxicity in the colon and liver of Big Blue rats. ---
25  2003 Effect of high sucrose diet on cytochrome P450 1A and heterocyclic amine mutagenesis. AROD, EROD, HCAs, MROD
26  2002 Chemoprotective effects of garden cress (Lepidium sativum) and its constituents towards 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ)-induced genotoxic effects and colonic preneoplastic lesions. ACF, BITC, GST, GT, SCGE, UDPGT
27  2002 DNA damage and metallothionein synthesis in human hepatoma cells (HepG2) exposed to cadmium. ---
28  2002 Mammary gland carcinogenesis by food-derived heterocyclic amines and studies on the mechanisms of carcinogenesis of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). HCAs, PhIP
29  2001 Colonic cell proliferation, apoptosis and aberrant crypt foci development in rats given 2-amino-3-methylimidaz. ACF, BrdU, Chl, DMH, PhIP
30  2001 Contrasting effects of acute and chronic dietary exposure to 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ) on xenobiotic metabolising enzymes in the male Fischer 344 rat: implications for chemoprevention studies. ARE, NQO, pro, UGT
31  2001 Evaluation of the cytotoxicity, mutagenicity and antimutagenicity of emerging edible plants. NQNO
32  2000 "IARC group 2A Carcinogens" reported in cigarette mainstream smoke. ---
33  2000 Antimutagenicity of ethanol extracts of bee glue against environmental mutagens. 1-NP, 4-NO, ECD, EROD
34  2000 Bioactivation of the food mutagen 2-amino-3-methyl-imidazo[4, 5-f]quinoline (IQ) by prostaglandin-H synthase and by monooxygenases: DNA adduct analysis. PHS
35  2000 Effects of human intestinal flora on mutagenicity of and DNA adduct formation from food and environmental mutagens. HFA
36  2000 Evaluation of the single cell gel electrophoresis assay with human hepatoma (Hep G2) cells. CP, HMPA, NDMA, NMU, SCGE, TF
37  2000 Use of genetically engineered Salmonella typhimurium OY1002/1A2 strain coexpressing human cytochrome P450 1A2 and NADPH-cytochrome P450 reductase and bacterial O-acetyltransferase in SOS/umu assay. CYP1A2, HCAs, OAT
38  1999 A new modification of the 32P-post-labeling method to recover IQ-DNA adducts as mononucleotides. NP1, PDE I, PNK
39  1999 Antimutagenic effects and possible mechanisms of action of vitamins and related compounds against genotoxic heterocyclic amines from cooked food. FAD, HCA, N-OH-IQ, NADPH, PhIP
40  1999 Genotoxic effects of heterocyclic aromatic amines in human derived hepatoma (HepG2) cells. CHO, HAAs, MN, PhIP
41  1999 Low-dose-dependent carcinogenic potential of 2-amino-3-methylimidazo[4,5-f]quinoline in the immunodeficient (SCID) mouse colon. ACF, SCID
42  1999 Mutagenicity and co-mutagenicity of static magnetic fields detected by bacterial mutation assay. 2-AAF, 2AA, 4NQO, 9AA, AF-2, EMS, ENNG, MNNG
43  1999 New O-acetyltransferase-deficient Ames Salmonella strains generated by specific gene disruption. 1,8-DNP, 2-NF, CAT, Cmr, OAT
44  1998 Scavenging effect of various tea extracts on superoxide derived from the metabolism of mutagens. AFB1
45  1997 Effects of high- and low-risk diets on gut microflora-associated biomarkers of colon cancer in human flora-associated rats. HR, LR
46  1997 Induction of DNA damage by risk factors of colon cancer in human colon cells derived from biopsies. DNC, LCA, MNNG, PhIP
47  1997 Influence of carcinogen binding by lactic acid-producing bacteria on tissue distribution and in vivo mutagenicity of dietary carcinogens. AFB1, HMA
48  1997 The ability of two cooked food mutagens to induce aberrant crypt foci in mice. AOM, DMH-2HCl, PhIP
49  1996 Antimutagenic effect of methanolic extracts from peanut hulls. AFB1, MEPH, NQNO
50  1996 Naturally occurring diallyl disulfide inhibits the formation of carcinogenic heterocyclic aromatic amines in boiled pork juice. AM, AMS, DAD, DAS, DPD, MRPs
51  1996 Refined carbohydrate enhancement of aberrant crypt foci (ACF) in rat colon induced by the food-borne carcinogen 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ). ACF, AOM, DMH
52  1996 The role of aberrant crypt foci induced by the two heterocyclic amines 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ) and 2-amino-1-methyl-6-phenyl-imidazo[4,5-b]pyridine (PhIP) in the development of colon cancer in mice. ACF, PhIP
53  1995 DNA adducts of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) in colon, bladder, and kidney of congenic mice differing in Ah responsiveness and N-acetyltransferase genotype. ---
54  1995 Effect of cigarette smoke on the mutagenic activation of various carcinogens in hamster. AFB1, BOP, CS, MC, PB
55  1995 Inhibition of mutagenesis of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) by coumarins and furanocoumarins, chromanones and furanochromanones. ---
56  1995 Non-specific inhibition of cytochrome P450 activities by chlorophyllin in human and rat liver microsomes. ---
57  1995 Protective effect of N-acetylcysteine against heterocyclic amine-induced cardiotoxicity in cultured myocytes and in rats. HAs, PhIP
58  1994 32P-post-labelling analysis of DNA adducts formed by food-derived heterocyclic amines: evidence for incomplete hydrolysis and a procedure for adduct pattern simplification. HA, PhIP
59  1994 Antimutagenicity of Maillard reaction products from amino acid/sugar model systems against 2-amino-3-methylimidazo-[4,5-f]quinoline: the role of pyrazines. ---
60  1994 Cardiotoxicity of heterocyclic amine food mutagens in cultured myocytes and in rats. PhIP
61  1994 Cell uptake and DNA adduct formation of the 2-amino-3 methyl-imidazo (4,5-f) quinoline in human enterocytes and chick embryo liver cells. ---
62  1994 Cumulative effects of chromosome aberrations and sister chromatid exchanges in rat liver induced in vivo by heterocyclic amines. nitro-IQ, SCEs
63  1994 Genotoxicity and carcinogenicity in rats and mice of 2-amino-3,6-dihydro-3-methyl-7H-imidazolo[4,5-f]quinolin-7- one: an intestinal bacterial metabolite of 2-amino-3-methyl-3H-imidazo[4,5-f]quinoline. NMU
64  1994 Heterocyclic amines formed by cooking food: comparison of bioassay results with other chemicals in the Carcinogenic Potency Database. CPDB, HA
65  1994 In vitro effect of vegetable and fruit juices on the mutagenicity of 2-amino-3-methylimidazo[4,5-f]quinoline, 2-amino-3,4-dimethylimidazo[4,5-f]quinoline and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline. ---
66  1994 Inhibition of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ)-DNA binding in rats given chlorophyllin: dose-response and time-course studies in the liver and colon. Chl
67  1993 Antimutagenic potency of chlorophyllin in the Salmonella assay and its correlation with binding constants of mutagen-inhibitor complexes. Chl, MR50
68  1993 Application of the 32P-postlabelling assay to the inhibition of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ)-DNA adduct formation by dietary fatty acids. MO
69  1993 Conversion of IQ to 7-OHIQ by gut microflora. HFA
70  1993 Effects of risk-associated human dietary macrocomponents on processes related to carcinogenesis in human-flora-associated (HFA) rats. GF, HFA, PhIP
71  1993 Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases. ---
72  1993 Mutagenic activation of IQ, PhIP and MeIQx by hepatic microsomes from rat, monkey and man: low mutagenic activation of MeIQx in cynomolgus monkeys in vitro reflects low DNA adduct levels in vivo. PhIP
73  1993 The effects of transgalactosylated oligosaccharides on gut flora metabolism in rats associated with a human faecal microflora. TOS
74  1993 The heterocyclic amines IQ and MeIQx show no promotive effect in a short-term in vivo liver carcinogenesis assay. DEN, GST-P
75  1992 Antimutagenic effect of Maillard browning products obtained from amino acids and sugars. MRPs
76  1992 Inhibition of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ)-DNA binding by chlorophyllin: studies of enzyme inhibition and molecular complex formation. Chl
77  1992 Molecular cloning of monkey P450 1A1 cDNA and expression in yeast. 3-MC, APase
78  1992 Toxicological significance of dog liver cytochrome P-450: examination with the enzyme expressed in Saccharomyces cerevisiae using recombinant expression plasmid. ADH, cDNA
79  1990 Heterocyclic amines produced in cooked food: unavoidable xenobiotics. GST-P, PhIP
80  1990 Inhibitory effects of carcinogenic tryptophan pyrolysis products on phytohemagglutinin-induced blast transformation of human lymphocytes. PHA
81  1990 Mechanism of the in vitro antimutagenic action of retinol. ---
82  1990 Metabolic activation of aflatoxin B1 and 2-amino-3-methylimidazo[4,5-f]-quinoline by human adult and fetal livers. AFB1
83  1989 An efficient and convenient method for the purification of mutagenic heterocyclic amines in heated meat products. HPLC, PhIP
84  1989 Mutagenic nitrenes/nitrenium ions from azido-imidazoarenes and their structure-activity relationships. ---
85  1989 Preferential induction of the rat hepatic P450 I proteins by the food carcinogen 2-amino-3-methyl-imidazo[4,5-f]quinoline. ---
86  1988 Conversion of IQ, a dietary pyrolysis carcinogen to a direct-acting mutagen by normal intestinal bacteria of humans. HOIQ
87  1988 Molecular cloning of rat phosphoprotein phosphatase 2A beta cDNA and increased expressions of phosphatase 2A alpha and 2A beta in rat liver tumors. ---
88  1988 Mutagenic and carcinogenic heterocyclic amines in Chinese cooked foods. PhIP
89  1987 Anaerobic metabolism of 2-amino-3-methyl-3H-imidazo[4,5-f]quinoline (IQ) by human fecal flora. ---
90  1987 Fluorometric detection of 2-amino-3-methylimidazo[4,5-f]quinoline, 2-amino-3,4-dimethylimidazo[4,5-f]quinoline and their N-acetylated metabolites excreted by the rat. ---
91  1987 Mutagenicity of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) in the granuloma pouch assay. MNNG
92  1985 Activated c-raf gene in a rat hepatocellular carcinoma induced by 2-amino-3-methylimidazo[4,5-f]quinoline. ---
93  1985 Activated oncogenes in a rat hepatocellular carcinoma induced by 2-amino-3-methylimidazo[4,5-f]quinoline. ---
94  1985 Genotoxicity of the cooked-food mutagens IQ and MeIQ in primary cultures of rat, hamster, and guinea pig hepatocytes. ---