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■ Abbreviation / Long Form : IRF / interferon regulatory factor

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Total Number of Papers: 525
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Abbreviation:   IRF  (>> Co-occurring Abbreviation)
Long Form:   interferon regulatory factor
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No. Year Title Co-occurring Abbreviation
2019 Anthriscus sylvestris root extract reduces allergic lung inflammation by regulating interferon regulatory factor 4-mediated Th2 cell activation. OVA, Th
2019 Cooperation of PU.1 With IRF8 and NFATc1 Defines Chromatin Landscapes During RANKL-Induced Osteoclastogenesis. BMMs, NFATc1, OC, RANKL
2019 HIV-1-Mediated Suppression of IFN-alpha Production Is Associated with Inhibition of IRF-7 Translocation and PI3K/akt Pathway in Plasmacytoid Dendritic Cells. IFN-alpha, pDCs
2019 Identification, characterization and expression in response to Aeromonas hydrophila challenge of five interferon regulatory factors in Megalobrama amblycephala. ---
2019 IRF5 regulates unique subset of genes in dendritic cells during West Nile virus infection. DCs, PRR, WNV
2019 LEADeR role of miR-205 host gene as long noncoding RNA in prostate basal cell differentiation. ---
2019 Persistence of Integrase-Deficient Lentiviral Vectors Correlates with the Induction of STING-Independent CD8+ T Cell Responses. CTL, DCs, IDLVs, RIG-I, STING
2019 The Evolving Role of TRAFs in Mediating Inflammatory Responses. NF-kappaB, TNF
2019 The role of the PD-1/PD-L1 axis in macrophage differentiation and function during pregnancy. DMs, NP, PD-1, PD-L1, qRT-PCR, rh, RM
10  2019 Transfection reagent Lipofectamine triggers type I interferon signaling activation in macrophages. IFN
11  2019 UBE3A regulates the transcription of IRF, an anti-viral immunity. AS
12  2018 A Positive Feedback Amplifier Circuit That Regulates Interferon (IFN)-Stimulated Gene Expression and Controls Type I and Type II IFN Responses. GAF, IFN, ISG, ISGF3, ISRE, JAK, STAT
13  2018 Ankyrin repeat domain 1 regulates innate immune responses against herpes simplex virus 1: Apotential role in eczema herpeticum. AD, ANKRD1, HSV, NA
14  2018 Both IRF3 and especially IRF7 play a key role to orchestrate an effective cerebral inflammatory response in a mouse model of herpes simplex virus encephalitis. HSE, WT
15  2018 Cirsimarin, a flavone glucoside from the aerial part of Cirsium japonicum var. ussuriense (Regel) Kitam. ex Ohwi, suppresses the JAK/STAT and IRF-3 signaling pathway in LPS-stimulated RAW 264.7 macrophages. COX-2, IL, iNOS, JAK, MAPK, NO, PGE2, STATs, TNF-alpha
16  2018 Decitibine improve the efficiency of anti-PD-1 therapy via activating the response to IFN/PD-L1 signal of lung cancer cells. CTLs
17  2018 Deletion of interferon-regulatory factor-1 results in cognitive impairment. AT2, BCAS, IRF-1KO
18  2018 Differential regulation of NF-kB and IRF target genes as they relate to fatigue in patients with head and neck cancer. CTRA, HNC, HPV, NF-kB, PBMC
19  2018 Distinctive Roles for Type I and Type II Interferons and Interferon Regulatory Factors in the Host Cell Defense against Varicella-Zoster Virus. IFNs, VZV
20  2018 Establishment of Novel Reporter Cells Stably Maintaining Transcription Factor-driven Human Secreted Alkaline Phosphatase Expression. EBNA, LPS, NF-kB, SEAP, TLR
21  2018 Expression and functional characterization of interferon regulatory factors 4, 8, and 9 in large yellow croaker (Larimichthys crocea). CDS
22  2018 Functional elucidation of LvToll 3 receptor from P.vannamei through RNA interference and its potential role in the shrimp antiviral response. dsRNA, PAMPs, RNAi
23  2018 Genomic Characterization of Lactobacillus delbrueckii TUA4408L and Evaluation of the Antiviral Activities of its Extracellular Polysaccharides in Porcine Intestinal Epithelial Cells. APS, EPS, IFN, MxA, NF-kappaB, PIE, TLR3
24  2018 Hesperetin Prevents Bone Resorption by Inhibiting RANKL-Induced Osteoclastogenesis and Jnk Mediated Irf-3/c-Jun Activation. Hes, RANKL
25  2018 Identification and functional characterization of interferon regulatory factor 7 involved in activation JAK/STAT pathway in miiuy croaker. FSGD, IFN
26  2018 Identification of alpha-Mangostin as an Agonist of Human STING. STING
27  2018 Increased expression of toll-like receptor 3, an anti-viral signaling molecule, and related genes in Alzheimer's disease brains. AD, IFN-beta, TLR3
28  2018 Interferon-Alpha Reduces Human Hippocampal Neurogenesis and Increases Apoptosis via Activation of Distinct STAT1-Dependent Mechanisms. CREB, IL-6, ISG15, STAT1, USP18
29  2018 Interferon-stimulated genes: new platforms and computational approaches. IFN, ISGs, VSG
30  2018 IRF1 up-regulates isg15 gene expression in dsRNA stimulation or CSFV infection by targeting nucleotides -487 to -325 in the 5' flanking region. CSFV, dsRNA, IFN
31  2018 Irf8 regulates the progression of myeloproliferative neoplasm-like syndrome via Mertk signaling in zebrafish. MPN
32  2018 lncRNA AFAP1-AS1 Promotes Migration and Invasion of Non-Small Cell Lung Cancer via Up-Regulating IRF7 and the RIG-I-Like Receptor Signaling Pathway. AFAP1-AS1, ceRNAs, IFN, IL, lncRNAs, NSCLC
33  2018 Long-acting beta2-adrenoreceptor agonists suppress type 1 interferon expression in human plasmacytoid dendritic cells via epigenetic regulation. Epac, IFN, LABA, MAPK, pDCs, TLR
34  2018 MicroRNA-3662 expression correlates with antiviral drug resistance in adult T-cell leukemia/lymphoma cells. ATLL
35  2018 miR-18a-5p promotes cell invasion and migration of osteosarcoma by directly targeting IRF2. miR-18a-5p, miRNAs, OS, RT-qPCR
36  2018 Nafamostat mesilate, a serine protease inhibitor, suppresses interferon-gamma-induced up-regulation of programmed cell death ligand 1 in human cancer cells. CTLs, ERK, HLA, IFN-gamma, mRNA, NF-kB, NM, PAR, PD-1, PD-L1, STAT
37  2018 Quantitation of IRF3 Nuclear Translocation in Heterogeneous Cellular Populations from Cervical Tissue Using Imaging Flow Cytometry. IFC
38  2018 Src Family Kinases Regulate Interferon Regulatory Factor 1 K63 Ubiquitination following Activation by TLR7/8 Vaccine Adjuvant in Human Monocytes and B Cells. IRF-1, SFKs, TIR, TLRs, TRAF6
39  2018 Structural and functional analysis of interferon regulatory factors (IRFs) reveals a novel regulatory model in an invertebrate, Crassostrea gigas. IRFs
40  2018 Thymoquinone Suppresses IRF-3-Mediated Expression of Type I Interferons via Suppression of TBK1. AP-1, IFN, III-I, LPS, TBK1, TQ
41  2017 A protective role of IRF3 and IRF7 signalling downstream TLRs in the development of vein graft disease via type I interferons. IFN, TLR, VGD
42  2017 Cysteine-rich 61-associated gene expression profile alterations in human glioma cells. CYR61, DDX58, DEGs, FC, IFI, IFN, PPI, STAT1, TFs
43  2017 Estrogen Receptor-Dependent Regulation of Dendritic Cell Development and Function. cDC, DCs, ERs, IFNs, pDC
44  2017 FOXO3, IRF4, and xIAP Are Correlated with Immune Activation in HIV-1-Infected Men Who Have Sex with Men During Early HIV Infection. ELF, FOXO, HCs, RPs, XIAP
45  2017 Hydroquinone suppresses IFN-beta expression by targeting AKT/IRF3 pathway. HQ, IFN, LPS, TBK1, TRIF
46  2017 Identification of a small molecule that primes the type I interferon response to cytosolic DNA. ISGs, ISRE
47  2017 Inactivation of the putative ubiquitin-E3 ligase PDLIM2 in classical Hodgkin and anaplastic large cell lymphoma. ALCL, AP-1, cHL, HRS, JAK/STAT, NF-kappaB, PMA, TFs
48  2017 Influenza a virus NS1 protein induced A20 contributes to viral replication by suppressing interferon-induced antiviral response. IAV, IFN, ISGs, NS, RIG-I
49  2017 Interferon Regulatory Factor 5 Controls Necrotic Core Formation in Atherosclerotic Lesions by Impairing Efferocytosis. ---
50  2017 Interferon regulatory factor-1 (IRF-1) protects against chikungunya virus induced immunopathology by restricting infection in muscle cells. IFN, IRF-1, ISGs, RRV
51  2017 IRF8-dependent molecular complexes control the Th9 transcriptional program. ---
52  2017 Knockdown of IRF3 inhibits extracellular matrix expression in keloid fibroblasts. alpha-SMA, ECM, IRF3, KFs
53  2017 MicroRNA-302d targets IRF9 to regulate the IFN-induced gene expression in SLE. IFN, ISGs, SLE
54  2017 Neuropharmacological Study of ATP Receptors, Especially in the Relationship between Glia and Pain. P2X4Rs
55  2017 Oncostatin M induces RIG-I and MDA5 expression and enhances the double-stranded RNA response in fibroblasts. IFN-gamma, IL, ISG, MDA5, OSM, PML, PTPN2, RIG, SUMO1
56  2017 Putting Glioblastoma in Its Place: IRF3 Inhibits Invasion. CK
57  2017 Reciprocal regulation of the Il9 locus by counteracting activities of transcription factors IRF1 and IRF4. Th9
58  2017 Rubicon Modulates Antiviral Type I Interferon (IFN) Signaling by Targeting IFN Regulatory Factor 3 Dimerization. IFN, TLR
59  2017 Selective inhibition of EZH2 by a small molecule inhibitor regulates microglial gene expression essential for inflammation. CNS, EZH2, STAT, TFs
60  2017 STRAP positively regulates TLR3-triggered signaling pathway. IFN, NF-kappaB, TLR
61  2017 Targeting Interferon Regulatory Factor for Cardiometabolic Diseases: Opportunities and Challenges. ---
62  2017 Transcriptional mechanisms that control expression of the macrophage colony-stimulating factor receptor locus. CSF, FIRE
63  2016 Bcl6 Sets a Threshold for Antiviral Signaling by Restraining IRF7 Transcriptional Program. Bcl, IFN
64  2016 Dengue virus infection induces interferon-lambda1 to facilitate cell migration. DCs, DENV, IFN-lamda, NF-kappaB, NS1, TLR
65  2016 Disrupted cooperation between transcription factors across diverse cancer types. LUAD, LUSC, TFs
66  2016 Full Spectrum of LPS Activation in Alveolar Macrophages of Healthy Volunteers by Whole Transcriptomic Profiling. RNA-Seq, TRIF, USP
67  2016 Genetic Variation of Goat Interferon Regulatory Factor 3 Gene and Its Implication in Goat Evolution. MEC, PAML
68  2016 Grouper TRIM13 exerts negative regulation of antiviral immune response against nodavirus. MDA5, RGNNV, SGIV, TRIM
69  2016 Identification of Two Subgroups of Type I IFNs in Perciforme Fish Large Yellow Croaker Larimichthys crocea Provides Novel Insights into Function and Regulation of Fish Type I IFNs. ---
70  2016 IFN Regulatory Factors and Antiviral Innate Immunity: How Viruses Can Get Better. IFN, PRRs
71  2016 Inhibition of IRF3 expression reduces TGF-beta1-induced proliferation of hepatic stellate cells. alpha-SMA, HSC, IRF3
72  2016 Interferon regulatory factor 1 attenuates vascular remodeling; roles of angiotensin II type 2 receptor. AT2, AT2KO, IRF-1KO, WT
73  2016 Interferon Regulatory Factor 6 Has a Protective Role in the Host Response to Endotoxic Shock. ---
74  2016 IRF3 is involved in human acute myeloid leukemia through regulating the expression of miR-155. AML
75  2016 IRF3 promotes adipose inflammation and insulin resistance and represses browning. ---
76  2016 Irgm1 promotes M1 but not M2 macrophage polarization in atherosclerosis pathogenesis and development. APOE
77  2016 M2 Macrophage Transplantation Ameliorates Cognitive Dysfunction in Amyloid-beta-Treated Rats Through Regulation of Microglial Polarization. AD, NGF, TrkA
78  2016 Neddylation is required for herpes simplex virus type I (HSV-1)-induced early phase interferon-beta production. IFN-beta, IkappaB, LPS, NF-kappaB
79  2016 Pomalidomide in combination with dexamethasone results in synergistic anti-tumour responses in pre-clinical models of lenalidomide-resistant multiple myeloma. PomDex, RRMM
80  2016 Porcine circovirus type 2 induces type I interferon production via MyD88-IKKalpha-IRFs signaling rather than NF-kappaB in porcine alveolar macrophages in vitro. MyD88, PCV2
81  2016 Positive Darwinian selection within interferon regulatory factor genes of Gymnocypris przewalskii (Cyprinidae) on the Tibetan Plateau. TP
82  2016 PU.1 cooperates with IRF4 and IRF8 to suppress pre-B-cell leukemia. B-ALL
83  2016 RING domain is essential for the antiviral activity of TRIM25 from orange spotted grouper. IFP35, MyD88, RGNNV, SGIV, TRIM25
84  2016 Roles of Interferon Regulatory Factors in Chronic Myeloid Leukemia. CML
85  2016 Sequence and Expression Analysis of Interferon Regulatory Factor 10 (IRF10) in Three Diverse Teleost Fish Reveals Its Role in Antiviral Defense. IRF10, ORF
86  2016 Significant role for IRF3 in both T cell and APC effector functions during T cell responses. DCs, GrB, INAM
87  2016 STAT1 and IRF8 in Vascular Inflammation and Cardiovascular Disease: Diagnostic and Therapeutic Potential. CVD, ECs, STAT, TLR4-A, VSMCs
88  2016 Structural Basis of Intracellular TGF-beta Signaling: Receptors and Smads. FHA, R-Smads, TGF-beta
89  2016 Targeted inhibition of STATs and IRFs as a potential treatment strategy in cardiovascular disease. IFN, IL, STAT, TLR4
90  2016 Upregulation of Interferon Regulatory Factor 6 Promotes Neuronal Apoptosis After Traumatic Brain Injury in Adult Rats. TBI
91  2016 Zika Virus Infects Neural Progenitors in the Adult Mouse Brain and Alters Proliferation. ZIKV
92  2016 [The laboratory detection of intra-cellular factors of anti-viral defense under community-acquired pneumonia in evaluation of effects of low-intensity microwave radiation]. Tmem 173
93  2015 A bacterial cyclic dinucleotide activates the cytosolic surveillance pathway and mediates innate resistance to tuberculosis. c-di-AMP, cGAMP, CSP, IFN, PAMP, STING
94  2015 A role for the adaptor proteins TRAM and TRIF in toll-like receptor 2 signaling. TLRs
95  2015 A toll-like receptor 3 homologue that is up-regulated by poly I:C and DNA virus in turbot Scophthalmus maximus. ISRE, LRR, Sm, STATs, TIR, TLR3, TRBIV
96  2015 Activation of lymphotoxin-beta receptor enhances the LPS-induced expression of IL-8 through NF-kappaB and IRF-1. CREB, GSK, LTbetaR, MAPK, NF
97  2015 Activation of Vago by interferon regulatory factor (IRF) suggests an interferon system-like antiviral mechanism in shrimp. IFN, ISRE
98  2015 An Internally Translated MAVS Variant Exposes Its Amino-terminal TRAF-Binding Motifs to Deregulate Interferon Induction. IFN
99  2015 Analysis of a pair of END+ and END- viruses derived from the same bovine viral diarrhea virus stock reveals the amino acid determinants in Npro responsible for inhibition of type I interferon production. BVDV, CSFVs, END, pro
100  2015 Batf is important for IL-4 expression in T follicular helper cells. Tfh, Th