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■ Abbreviation / Long Form : KCs / Kupffer cells

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Total Number of Papers: 441
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Abbreviation:   KCs  (>> Co-occurring Abbreviation)
Long Form:   Kupffer cells
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No. Year Title Co-occurring Abbreviation
2019 alpha-ketoglutarate attenuates ischemia-reperfusion injury of liver graft in rats. alpha-KG, ALT, IRI, p-GSK3beta, SOCS1, TBIL
2019 Bioprinted liver provides early insight into the role of Kupffer cells in TGF-beta1 and methotrexate-induced fibrogenesis. MTX
2019 Bradykinin contributes to immune liver injury via B2R receptor-mediated pathways in trichloroethylene sensitized mice: A role in Kupffer cell activation. BK, KKS, OMLDT, TCE
2019 COMMD10-Guided Phagolysosomal Maturation Promotes Clearance of Staphylococcus aureus in Macrophages. ---
2019 Csf1r or Mer inhibition delays liver regeneration via suppression of Kupffer cells. CSF1R, LR, PH
2019 Effect of Soothing Gan (Liver) and Invigorating Pi (Spleen) Recipes on TLR4-p38 MAPK Pathway in Kupffer Cells of Non-alcoholic Steatohepatitis Rats. HE, HFD, IL, L-IR, H-IR, NASH, TC, TG, TLR4, TNF-alpha
2019 Exosomes from activated hepatic stellate cells contain GLUT1 and PKM2: a role for exosomes in metabolic switch of liver nonparenchymal cells. HIF-1, HSCs, LSECs
2019 Generation of mature kupffer cells from human induced pluripotent stem cells. DILI, iKCs, pKCs
2019 Lymphocyte Antigen 6 Complex, Locus C+ Monocytes and Kupffer Cells Orchestrate Liver Immune Responses Against Hepatitis B Virus in Mice. CCR2, CLD, HBV, Ly6C
10  2019 NLRP3 inflammasome activation from Kupffer cells is involved in liver fibrosis of Schistosoma japonicum-infected mice via NF-kappaB. LPS, NLRP3, SEA, SSLF
11  2019 Protective effects of curcumin against ischemia-reperfusion injury in the liver. I/R
12  2019 rhIL-1Ra reduces hepatocellular apoptosis in mice with acute liver failure mainly by inhibiting the activities of Kupffer cells. ALF, IL-1RI, rhIL-1Ra
13  2019 Role of macrophages in experimental liver injury and repair in mice. MoMo
14  2019 Self-Assembled "Off/On" Nanopomegranate for In Vivo Photoacoustic and Fluorescence Imaging: Strategic Arrangement of Kupffer Cells in Mouse Hepatic Lobules. CV, PA, PT
15  2019 STING-mediated inflammation in Kupffer cells contributes to progression of nonalcoholic steatohepatitis. HFD, MCD, mtDNA, NASH
16  2019 USP25 promotes endotoxin tolerance via suppressing K48-linked ubiquitination and degradation of TRAF3 in Kupffer cells. DUB, ET, JNK, TRAF3, USP25
17  2019 VEGF-C attenuates ischemia reperfusion injury of liver graft in rats. ALT, IRI, p-GSK3beta, SOCS1, TBIL, VEGF-C, VEGFR-3
18  2018 Abberent expression of NOR1 protein in tumor associated macrophages contributes to the development of DEN-induced hepatocellular carcinoma. HCC, NOR1, TAMs
19  2018 Activation of PPARgamma by Curcumin protects mice from ischemia/reperfusion injury induced by orthotopic liver transplantation via modulating polarization of Kupffer cells. I/R, NF-kappaB, OLT, PPARgamma, ROS
20  2018 Activin-A causes Hepatic stellate cell activation via the induction of TNFalpha and TGFbeta in Kupffer cells. HSCs, NASH
21  2018 An efficient method to isolate Kupffer cells eliminating endothelial cell contamination and selective bias. ---
22  2018 Catestatin Inhibits Obesity-Induced Macrophage Infiltration and Inflammation in the Liver and Suppresses Hepatic Glucose Production, Leading to Improved Insulin Sensitivity. CST, CST-KO, HGP, NCD
23  2018 Cathepsin B inhibition ameliorates the non-alcoholic steatohepatitis through suppressing caspase-1 activation. ASC, CTSB, ELISA, MCD, NAFLD
24  2018 Curcumin reduces Ly6Chi monocyte infiltration to protect against liver fibrosis by inhibiting Kupffer cells activation to reduce chemokines secretion. ---
25  2018 CXCL6-EGFR-induced Kupffer cells secrete TGF-beta1 promoting hepatic stellate cell activation via the SMAD2/BRD4/C-MYC/EZH2 pathway in liver fibrosis. HSC
26  2018 Danger-Associated Molecular Patterns (DAMPs): Molecular Triggers for Sterile Inflammation in the Liver. ALD, ATP, DAMPs, I/R, IFNs, NASH
27  2018 Dexamethasone restores transforming growth factor-beta activated kinase 1 expression and phagocytosis activity of Kupffer cells in cholestatic liver injury. DEX, IL, PBE, TAK1
28  2018 Dietary Lipids Differentially Shape Nonalcoholic Steatohepatitis Progression and the Transcriptome of Kupffer Cells and Infiltrating Macrophages. NAFLD, NASH
29  2018 Dysfunctional phagocytosis capacity, granulocyte recruitment and inflammatory factor secretion of Kupffer cells in diabetes mellitus reversed by Lidocaine. ICAM-1
30  2018 Extracellular Vesicles from Amnion-Derived Mesenchymal Stem Cells Ameliorate Hepatic Inflammation and Fibrosis in Rats. AMSCs, EVs, HFD, HSC, LPS, NASH, TLR4
31  2018 Fatty acid activates NLRP3 inflammasomes in mouse Kupffer cells through mitochondrial DNA release. mtDNA, NAFLD, NASH, PA
32  2018 Function and therapeutic advances of chemokine and its receptor in nonalcoholic fatty liver disease. HSCs, NAFLD, NASH
33  2018 HBeAg induces the expression of macrophage miR-155 to accelerate liver injury via promoting production of inflammatory cytokines. ---
34  2018 High Mobility Group Box-1 Drives Fibrosis Progression Signaling via the Receptor for Advanced Glycation End Products in Mice. ASH, DAMP, DILI, HCV, HMGB1, HSCs, NASH, p-ERK, PBC, pMEK, RAGE, WT
35  2018 IFI16 is involved in HBV-associated acute-on-chronic liver failure inflammation. CHB, HBV, HBV-ACLF, IFI16, PBMC
36  2018 IL-34 Inhibits Acute Rejection of Rat Liver Transplantation by Inducing Kupffer Cell M2 Polarization. AR
37  2018 IRE1alpha aggravates ischemia reperfusion injury of fatty liver by regulating phenotypic transformation of kupffer cells. ER stress, IRI, ROS
38  2018 Isoquercetin Improves Hepatic Lipid Accumulation by Activating AMPK Pathway and Suppressing TGF-beta Signaling on an HFD-Induced Nonalcoholic Fatty Liver Disease Rat Model. AMPK, HFD, IQ, LPS/FFA, NAFLD, SD, TGF-beta
39  2018 Ketamine ameliorates ischemia-reperfusion injury after liver autotransplantation by suppressing activation of Kupffer cells in rats. I/R, OLAT
40  2018 Kupffer cell depletion by gadolinium chloride aggravates liver injury after brain death in rats. BD, IL
41  2018 Kupffer Cells Survive Plasmodium berghei Sporozoite Exposure and Respond with a Rapid Cytokine Release. LDH, PRKCs
42  2018 Kupffer-derived matrix metalloproteinase-9 contributes to liver fibrosis resolution. MMPs, TAA, TIMPs
43  2018 Lipopolysaccharide Lowers Cholesteryl Ester Transfer Protein by Activating F4/80+Clec4f+Vsig4+Ly6C- Kupffer Cell Subsets. Clec4f, HDL, LPS, Ly6C, Vsig4
44  2018 Long noncoding RNA hypoxia-inducible factor 1 alpha-antisense RNA 1 promotes tumor necrosis factor-alpha-induced apoptosis through caspase 3 in Kupffer cells. ACLF, HIF1A-AS1, LEF-1, lncRNAs, PI, TNF-alpha
45  2018 Molecular hydrogen protects against ischemia-reperfusion injury in a mouse fatty liver model via regulating HO-1 and Sirt1 expression. I/R, MCDHF
46  2018 Multi-cellular transitional organotypic models to investigate liver fibrosis. HSCs, LSECs, PEMs
47  2018 Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) and liver fibrosis: A review. HSCs, NADPH
48  2018 Pivotal roles of Kupffer cells in the progression and regression of DDC-induced chronic cholangiopathy. DDC
49  2018 PPAR-gamma activation is associated with reduced liver ischemia-reperfusion injury and altered tissue-resident macrophages polarization in a mouse model. IRI
50  2018 PPARgamma alleviated hepatocyte steatosis through reducing SOCS3 by inhibiting JAK2/STAT3 pathway. IR, KCCM, NAFLD, PPARgamma, ROZ, SOCS3
51  2018 Preparation and Culture of Human Liver Resident Immune Cells. DCs, LSECs, NPCs
52  2018 Protective Effects of Apoptosis of Kupffer Cells Induced by Zoledronate Liposomes Following Hepatic Ischemia-Reperfusion Injury. ALT, AST, gamma-GT, IL-1, IRI, TNF-alpha
53  2018 RAMP1 in Kupffer cells is a critical regulator in immune-mediated hepatitis. CGRP, Con A, RAMP1
54  2018 Relationship between PK2 and number of Kupffer cells during the progression of liver fibrosis in patients with HBV HBV, PK2
55  2018 Role of altered immune cells in liver diseases: a review. NK
56  2018 Role of Kupffer cells in the progression of CRC liver metastases after the first stage of ALPPS. ALPPS, TAMs
57  2018 Role of miR-148a in Mitigating Hepatic Ischemia-Reperfusion Injury by Repressing the TLR4 Signaling Pathway via Targeting CaMKIIalpha in Vivo and in Vitro. HE, I/R
58  2018 S-allyl-glutathione improves experimental liver fibrosis by regulating Kupffer cell activation in rats. COL1A1, DAS, DMN, HSCs, HSP47, SAG
59  2018 SIRT1 upregulation protects against liver injury induced by a HFD through inhibiting CD36 and the NF‑kappaB pathway in mouse kupffer cells. HFD, NAFLD, NF, SIRT1
60  2018 Soluble fibrinogen-like protein 2 ameliorates acute rejection of liver transplantation in rat via inducing Kupffer cells M2 polarization. AAV-FGL2, AR, OLT, sFGL2
61  2018 Sphingosine kinase 1 promotes liver fibrosis by preventing miR-19b-3p-mediated inhibition of CCR2. alpha-SMA, BDL, BMT, HSCs, SphK, WT
62  2018 Spliceosome-Associated Protein 130 Exacerbates Alcohol-Induced Liver Injury by Inducing NLRP3 Inflammasome-Mediated IL-1beta in Mice. KO, SAP130, WT
63  2018 The role of hepatic macrophages in liver metastasis. ---
64  2018 The role of hepatic macrophages in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis. DAMPs, MDMs, NAFLD, NASH
65  2018 TIM‑4 blockade of KCs combined with exogenous TGF‑beta injection helps to reverse acute rejection and prolong the survival rate of mice receiving liver allografts. APC, AR, CD, LT, OLT, p38 MAPK, Th2
66  2018 TLR2 Stimulation Strengthens Intrahepatic Myeloid-Derived Cell-Mediated T Cell Tolerance through Inducing Kupffer Cell Expansion and IL-10 Production. iMDCs, P3C
67  2018 Toxicological Profiling of Metal Oxide Nanoparticles in Liver Context Reveals Pyroptosis in Kupffer Cells and Macrophages versus Apoptosis in Hepatocytes. NPs, REO
68  2018 Transcriptomic Analysis of Hepatic Cells in Multicellular Organotypic Liver Models. FAK, FXR, LSECs, NPCs, PPARalpha
69  2018 Treatment of cigarette smoke extract and condensate differentially potentiates palmitic acid-induced lipotoxicity and steatohepatitis in vitro. CS, CSE, NASH, PA, TPM
70  2018 Trichloroethene metabolite dichloroacetyl chloride induces apoptosis and compromises phagocytosis in Kupffer Cells: Activation of inflammasome and MAPKs. AIH, DCAC, TCE
71  2018 Ursolic acid ameliorates CCl4-induced liver fibrosis through the NOXs/ROS pathway. HCs, HSCs, NOXs, ROS, UA
72  2018 Use of Dual-Ligand Modification in Kupffer Cell-Targeted Liposomes To Examine the Contribution of Kupffer Cells to Accelerated Blood Clearance Phenomenon. ABC, APF, APM, DPF, DPM, PL
73  2018 [Cathepsin B in hepatic Kupffer cells regulates activation of TLR4-independent inflammatory pathways in mice with lipopolysaccharide-induced sepsis]. LPS, TLR4, WT
74  2017 A Liver Capsular Network of Monocyte-Derived Macrophages Restricts Hepatic Dissemination of Intraperitoneal Bacteria by Neutrophil Recruitment. LCMs
75  2017 A transgenic rat hepatocyte - Kupffer cell co-culture model for evaluation of direct and macrophage-related effect of poly(amidoamine) dendrimers. DILI
76  2017 Advanced Method for Isolation of Mouse Hepatocytes, Liver Sinusoidal Endothelial Cells, and Kupffer Cells. HCs, LSECs, MACS
77  2017 Asiatic acid protects against hepatic ischemia/reperfusion injury by inactivation of Kupffer cells via PPARgamma/NLRP3 inflammasome signaling pathway. AA, I/R, LPS, NLR, NPCs, PPARgamma
78  2017 Bisphenol A promotes hepatic lipid deposition involving Kupffer cells M1 polarization in male mice. BPA
79  2017 Cholesterol crystallization within hepatocyte lipid droplets and its role in murine NASH. IL-1 beta, LDs
80  2017 Decreasing CB1 receptor signaling in Kupffer cells improves insulin sensitivity in obese mice. ---
81  2017 Depletion of myeloid cells exacerbates hepatitis and induces an aberrant increase in histone H3 in mouse serum. BM, DTR, IL-6, LysM, TNF-alpha, WT
82  2017 Effect of inhibitors of endocytosis and NF-kB signal pathway on folate-conjugated nanoparticle endocytosis by rat Kupffer cells. AMR, COL, CPZ, EPI, IL-1beta, NDDS, NF-kB, NY, PDTC, TNF-alpha
83  2017 Elevated Expression of Chemokine CXCL13 in Chronic Hepatitis B Patients Links to Immune Control during Antiviral Therapy. CHB, CR, CXCL13, CXCR5, HBV
84  2017 Erythropoietin enhances Kupffer cell number and activity in the challenged liver. BM, EPO
85  2017 Exercise training enhances in vivo clearance of endotoxin and attenuates inflammatory responses by potentiating Kupffer cell phagocytosis. NAFLD
86  2017 Frontline Science: HIV infection of Kupffer cells results in an amplified proinflammatory response to LPS. ARTs
87  2017 Functionality based method for simultaneous isolation of rodent hepatic sinusoidal cells. HSCs, LSECs
88  2017 Hepatic stellate cells secreting WFA+ -M2BP: Its role in biological interactions with Kupffer cells. HSCs
89  2017 HMGA2, a driver of inflammation, is associated with hypermethylation in acute liver injury. ALI, HMGA2
90  2017 HMGB1 and Histones Play a Significant Role in Inducing Systemic Inflammation and Multiple Organ Dysfunctions in Severe Acute Pancreatitis. BT, MODS, SAP, SIRS
91  2017 Inactivation of Kupffer Cells by Selenizing Astragalus Polysaccharides Prevents CCl4-Induced Hepatocellular Necrosis in the Male Wistar Rat. APS, IFA, IHC, mRNA, sAPS3, SS
92  2017 Inhibition of NLRP3 inflammasome by thioredoxin-interacting protein in mouse Kupffer cells as a regulatory mechanism for non-alcoholic fatty liver disease development. HFD, IL-1beta, MCD, NAFL, NAFLD, NASH, NLR, PA, TXNIP, WT
93  2017 Investigating acetaminophen hepatotoxicity in multi-cellular organotypic liver models. LSECs, NPCs
94  2017 Investigation for role of tissue factor and blood coagulation system in severe acute pancreatitis and associated liver injury. SAP, TF, TF-MP
95  2017 JNK signaling is required for the MIP‑1alpha‑associated regulation of Kupffer cells in the heat stroke response. HS, IL
96  2017 Kupffer cells activation promoted binge drinking-induced fatty liver by activating lipolysis in white adipose tissues. FFA, TG
97  2017 Kupffer cells in immune activation and tolerance toward HBV/HCV infection. FasL, PD-L1, TLRs
98  2017 Melatonin protects mice against stress-induced inflammation through enhancement of M2 macrophage polarization. IL, MLT, RS, STAT
99  2017 MicroRNA-155 Deficiency in Kupffer Cells Ameliorates Liver Ischemia-Reperfusion Injury in Mice. IR, miR-155
100  2017 Molecular Imaging with Kupffer Cell-Targeting Nanobodies for Diagnosis and Prognosis in Mouse Models of Liver Pathogenesis. Clec, Con A, IHC, MCD, Nbs, SPECT, VSIG4