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■ Abbreviation / Long Form : KORs / kappa-opioid receptors

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Total Number of Papers: 91
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Abbreviation:   KORs  (>> Co-occurring Abbreviation)
Long Form:   kappa-opioid receptors
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No. Year Title Co-occurring Abbreviation
2022 Adverse Effects of Repeated, Intravenous Morphine on Recovery after Spinal Cord Injury in Young, Male Rats Are Blocked by a Kappa Opioid Receptor Antagonist. nor-BNI, SCI
2022 Dynorphin promotes stress-induced depressive behaviors by inhibiting ventral pallidal neurons in rats. VGCCs, VP
2022 Dysregulated kappa-opioid receptors in the medial prefrontal cortex contribute to working memory deficits in alcohol dependence. AUD, DYN, mPFC, nor-BNI
2022 Modulation of 5-HT release by dynorphin mediates social deficits during opioid withdrawal. DA, NAc
2022 Pharmacological activation of kappa opioid receptors in the nucleus accumbens core and ventral tegmental area increases the aversive effects of nicotine. NAcc, VTA
2022 Role of kappa-opioid and mu-opioid receptors in pruritus: Peripheral and central itch circuits. MORs
2021 100 Hz Electroacupuncture Alleviated Chronic Itch and GRPR Expression Through Activation of Kappa Opioid Receptors in Spinal Dorsal Horn. DYN, EA, GRPR, nor-BNI
2021 Amygdalar κ-opioid receptor-dependent upregulating glutamate transporter 1 mediates depressive-like behaviors of opioid abstinence. GLT-1, MAPK, NAc
2021 Blockade of kappa-opioid receptors amplifies microglia-mediated inflammatory responses. LPS, MACs
10  2021 Comparative study of dezocine, pentazocine and tapentadol on antinociception and physical dependence. alpha2-AR, MORs, NRI
11  2021 Data-driven analysis of kappa opioid receptor binding in major depressive disorder measured by positron emission tomography. HDRS, MDD, PET
12  2021 kappa-Opioid receptor antagonism reverses heroin withdrawal-induced hyperalgesia in male and female rats. ---
13  2021 Release of endogenous dynorphin opioids in the prefrontal cortex disrupts cognition. nor-BNI, PFC
14  2021 Replacing a Palatable High-Fat Diet with a Low-Fat Alternative Heightens kappa-Opioid Receptor Control over Nucleus Accumbens Dopamine. HFD, NAc
15  2021 Synthesis and Pharmacological Evaluation of Fluorinated Quinoxaline-Based kappa-Opioid Receptor (KOR) Agonists Designed for PET Studies. KOR
16  2021 The kappa opioid receptor may be a potential tumor suppressor by regulating angiogenesis in breast cancer. ---
17  2020 The kappa opioid receptor antagonist aticaprant reverses behavioral effects from unpredictable chronic mild stress in male mice. UCMS
18  2019 Kappa Opioid Receptors Drive a Tonic Aversive Component of Chronic Pain. ---
19  2019 Social status and demographic effects of the kappa opioid receptor: a PET imaging study with a novel agonist radiotracer in healthy volunteers. BMI, BSMSS, MA1, PET, TACs, VT
20  2018 Estrogen Regulation of GRK2 Inactivates Kappa Opioid Receptor Signaling Mediating Analgesia, But Not Aversion. GRK2, KOR
21  2018 Females are less sensitive than males to the motivational- and dopamine-suppressing effects of kappa opioid receptor activation. DYN, FSCV, ICSS, NAc, TH, VTA
22  2017 Age-dependent regulation of GABA transmission by kappa opioid receptors in the basolateral amygdala of Sprague-Dawley rats. BLA, CeA, sIPSCs
23  2017 Dezocine exhibits antihypersensitivity activities in neuropathy through spinal mu-opioid receptor activation and norepinephrine reuptake inhibition. DORs, MOR, NRI
24  2017 Effects of pharmacological manipulation of the kappa opioid receptors on the aversive effects of nicotine. CTA
25  2017 Heterodimerization of apelin and opioid receptors and cardiac inotropic and lusitropic effects of apelin in 2K1C hypertension: Role of pERK1/2 and PKC. ---
26  2017 Insights into the Role of Opioid Receptors in the GI Tract: Experimental Evidence and Therapeutic Relevance. DOR, MORs
27  2017 Kappa opioid receptor antagonists: A possible new class of therapeutics for migraine prevention. CeA, MOH, nor-BNI
28  2017 Kappa Opioid Receptors Mediate Heterosynaptic Suppression of Hippocampal Inputs in the Rat Ventral Striatum. HP, KOR, MSNs, VS
29  2017 Long-term plasticity of corticostriatal synapses is modulated by pathway-specific co-release of opioids through kappa-opioid receptors. LTP, SPNs, TBS
30  2017 Role of kappa-Opioid Receptors in the Bed Nucleus of Stria Terminalis in Reinstatement of Alcohol Seeking. BNST
31  2017 The long-term effects of stress and kappa opioid receptor activation on conditioned place aversion in male and female California mice. NAc
32  2016 Antidepressant-like Effects of Buprenorphine are Mediated by Kappa Opioid Receptors. BPN, DOR, FST, ORL-1, UCMS
33  2016 Dopamine and opioid systems interact within the nucleus accumbens to maintain monogamous pair bonds. DA, NAc
34  2016 Dynorphin Controls the Gain of an Amygdalar Anxiety Circuit. BLA, BNST
35  2016 Early-Life Social Isolation Stress Increases Kappa Opioid Receptor Responsiveness and Downregulates the Dopamine System. DA, GH, nor-BNI, SI
36  2016 Kappa-opioid receptors differentially regulate low and high levels of ethanol intake in female mice. DA, DAT, EtOH
37  2016 Sex Differences in Kappa Opioid Receptor Function and Their Potential Impact on Addiction. DYN, MC1R, MORs, PDYN
38  2016 The contribution of activated peripheral kappa opioid receptors (kORs) in the inflamed knee joint to anti-nociception. MSA, ORs
39  2015 Activation of kappa Opioid Receptors in Cutaneous Nerve Endings by Conorphin-1, a Novel Subtype-Selective Conopeptide, Does Not Mediate Peripheral Analgesia. ---
40  2015 Effects of acute and chronic social defeat stress are differentially mediated by the dynorphin/kappa-opioid receptor system. DA, DYN, SDS
41  2015 Functional selectivity of kappa opioid receptor agonists in peripheral sensory neurons. ERK, JNK, Sal-A
42  2015 High-dose pentazocine antagonizes the antinociception induced by high-dose morphine. nor-BNI
43  2015 Kappa opioid receptor signaling in the brain: Circuitry and implications for treatment. CRF
44  2015 mu and kappa opioid receptor distribution in the monogamous titi monkey (Callicebus cupreus): implications for social behavior and endocrine functioning. CG, MORs, NUDAPs
45  2015 Prefrontal Cortical Kappa Opioid Receptors Attenuate Responses to Amygdala Inputs. BLA, mPFC
46  2015 The kappa-opioid receptor antagonist, nor-binaltorphimine (nor-BNI), decreases morphine withdrawal and the consequent conditioned place aversion in rats. CPA, nor-BNI
47  2014 An Improved Antagonist Radiotracer for the kappa-Opioid Receptor: Synthesis and Characterization of (11)C-LY2459989. MA1
48  2014 Characteristics of TRK-130 (Naltalimide), a novel opioid ligand, as a new therapeutic agent for overactive bladder. DORs, MORs, OAB, RBCs
49  2014 Low dosage of rimonabant leads to anxiolytic-like behavior via inhibiting expression levels and G-protein activity of kappa opioid receptors in a cannabinoid receptor independent manner. CB1, CB1KO, CHO
50  2013 Ablation of kappa-opioid receptors from brain dopamine neurons has anxiolytic-like effects and enhances cocaine-induced plasticity. Cre, DA, DAT, qPCR
51  2013 Development of kappa opioid receptor antagonists. DYN, GPCRs
52  2013 Dynorphins regulate the strength of social memory. ---
53  2013 Kappa opioid receptors regulate stress-induced cocaine seeking and synaptic plasticity. VTA
54  2013 kappa-Opioid receptors in the central amygdala regulate ethanol actions at presynaptic GABAergic sites. CeA, IPSCs
55  2013 Locus coeruleus kappa-opioid receptors modulate reinstatement of cocaine place preference through a noradrenergic mechanism. CPP, LC, NA
56  2013 Pain-related depression of the mesolimbic dopamine system in rats: expression, blockade by analgesics, and role of endogenous kappa-opioids. ICSS, NAc DA, nor-BNI, PDYN
57  2013 Prefrontal cortical kappa-opioid receptor modulation of local neurotransmission and conditioned place aversion. DA, mPFC, nor-BNI
58  2013 Role of kappa-opioid receptors in stress and anxiety-related behavior. ---
59  2013 Sex differences in sensitivity to the depressive-like effects of the kappa opioid receptor agonist U-50488 in rats. ---
60  2012 Repeated stress dysregulates kappa-opioid receptor signaling in the dorsal raphe through a p38alpha MAPK-dependent mechanism. DRN, MAPK
61  2012 Stimulation of peripheral kappa opioid receptors inhibits inflammatory hyperalgesia via activation of the PI3Kgamma/AKT/nNOS/NO signaling pathway. MOR
62  2012 Targeting dynorphin/kappa opioid receptor systems to treat alcohol abuse and dependence. DYNs
63  2011 Blockade of kappa opioid receptors attenuates the development of depressive-like behaviors induced by cocaine withdrawal in rats. FST, ICSS
64  2011 Kappa opioid receptor localization and coupling to nitric oxide production in cells of the anterior chamber. ICBs, L-NAME, NO, nor-BNI, NPCE, SPR
65  2011 Kappa opioid receptors mediate where fear is expressed following extinction training. CS, i.c.v, nor-BNI
66  2011 kappa-Opioid receptor inhibition of calcium oscillations in spinal cord neurons. DIV, DYN
67  2011 Membrane-delimited proteolytic regulation of opioid receptors. MOR
68  2010 Depressive-like effects of the kappa opioid receptor agonist salvinorin A are associated with decreased phasic dopamine release in the nucleus accumbens. ICSS, NAc, salvA
69  2010 Medial dorsal hypothalamus mediates the inhibition of reward seeking after extinction. CTB, IL-PFC, MDH, PVT
70  2010 Transcriptional and epigenetic regulation of opioid receptor genes: present and future. DORs, MORs, ORs
71  2009 Dynorphin, stress, and depression. ---
72  2009 Salvinorin A inhibits colonic transit and neurogenic ion transport in mice by activating kappa-opioid and cannabinoid receptors. CB, GI, SA
73  2008 Exposure to the selective kappa-opioid receptor agonist salvinorin A modulates the behavioral and molecular effects of cocaine in rats. salvA
74  2008 Inhibitory effect of salvinorin A, from Salvia divinorum, on ileitis-induced hypermotility: cross-talk between kappa-opioid and cannabinoid CB(1) receptors. ---
75  2008 Kappa-opioid system regulates the long-lasting behavioral adaptations induced by early-life exposure to methylphenidate. MPH, PD, VEH
76  2008 The kappa-opioid agonist U69,593 blocks cocaine-induced enhancement of brain stimulation reward. ICSS, MFB
77  2007 Anxiolytic-like effects of kappa-opioid receptor antagonists in models of unlearned and learned fear in rats. EPM, FPS, norBNI, OF
78  2007 Human neural precursor cells express functional kappa-opioid receptors. MORs, NPCs, NSCs
79  2007 Opioid systems in the dentate gyrus. DG, LTP, PP
80  2005 Identification of the molecular mechanisms by which the diterpenoid salvinorin A binds to kappa-opioid receptors. GPCR
81  2004 A Purkinje cell specific GoLoco domain protein, L7/Pcp-2, modulates receptor-mediated inhibition of Cav2.1 Ca2+ channels in a dose-dependent manner. ---
82  2004 Agonist-induced regulation and trafficking of kappa opioid receptors. ---
83  2004 Kappa opioid receptors in rat spinal cord: sex-linked distribution differences. EM
84  2004 Salvinorin A: a novel and highly selective kappa-opioid receptor agonist. ---
85  2003 Activation of kappa-opioid receptors inhibits pruritus evoked by subcutaneous or intrathecal administration of morphine in monkeys. ---
86  2003 Analgesia from a peripherally active kappa-opioid receptor agonist in patients with chronic pancreatitis. ---
87  2003 Mu- and delta-opioid receptor antagonists decrease proliferation and increase neurogenesis in cultures of rat adult hippocampal progenitors. AHPs, MAPK
88  2001 Kappa opioid receptor density is consistent along the rostrocaudal axis of the female rat spinal cord. ---
89  2000 Kappa opioid receptors in rat spinal cord vary across the estrous cycle. ---
90  1996 Kappa opioid receptor-like immunoreactivity in guinea pig brain: ultrastructural localization in presynaptic terminals in hippocampal formation. KT
91  1996 kappa opioid receptors in human microglia downregulate human immunodeficiency virus 1 expression. HIV-1