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■ Abbreviation / Long Form : LC3-II / light chain 3-II

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Total Number of Papers: 218
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Abbreviation:   LC3-II  (>> Co-occurring Abbreviation)
Long Form:   light chain 3-II
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No. Year Title Co-occurring Abbreviation
2020 Activation of Mechanistic Target of Rapamycin (mTOR) in Human Endothelial Cells Infected with Pathogenic Spotted Fever Group Rickettsiae. ECs, mTOR, p70S6K, PKC
2020 Adaptive Autophagy Offers Cardiorenal Protection in Rats with Acute Myocardial Infarction. 3-MA, AMI, LVSP, uKIM1, uNGAL
2020 Chronic Stimulation of the Autophagy-inducing Ingredient of Areca Nut Promotes Tumor Growth In Vivo Through Up-regulation of Tumoral Autophagy. 3-MA, CAS, CQ, SF
2020 Clozapine protects adult neural stem cells from ketamine-induced cell death in correlation with decreased apoptosis and autophagy. BrdU, DG, NMDA, NSCs, SVZ
2020 Effect of probucol on autophagy and apoptosis in the penile tissue of streptozotocin-induced diabetic rats. Bax, Bcl-2, ICP, mTOR, SD, STZ
2020 Elevation of hepatic autophagy and antioxidative capacity by endurance exercise is associated with suppression of apoptosis in mice. ATG7, CuZnSOD, EXE, GPx, LAMP2, mTOR, pAMPK, Prx3
2020 Granulosa cells provide elimination of apoptotic oocytes through unconventional autophagy-assisted phagocytosis. ACIP, ATG5, GCs, INSERM
2020 Hinokitiol induces cell death and inhibits epidermal growth factor-induced cell migration and signaling pathways in human cervical adenocarcinoma. FAK, JNK, PARP, SA-beta-gal
2020 Hydroxysafflor yellow A induces autophagy in human liver cancer cells by regulating Beclin 1 and ERK expression. CQ, HSYA
10  2020 IGF-1 inhibits MPTP/MPP+-induced autophagy on dopaminergic neurons through the IGF-1R/PI3K-Akt-mTOR pathway and GPER. DA, GPER, IGF-1, MPTP, mTOR, PD, SN, TH
11  2020 Implications of miRNAs on TGF-beta/TAK1/mTOR pathway in mediating the renoprotective effects of pentoxifylline against cisplatin-induced nephrotoxicity in rats. CIS, mTOR, PTX, TGF-beta, TGFbetaR-1
12  2020 Inhibition of excessive mitophagy by N-acetyl-L-tryptophan confers hepatoprotection against Ischemia-Reperfusion injury in rats. 3-MA, ATG-7, CCK-8, EM, HIRI, I/R, L-NAT, mtDNA, qRT-PCR, SD
13  2020 Light-triggered selective ROS-dependent autophagy by bioactive nanoliposomes for efficient cancer theranostics. CfAc, NIR, ROS
14  2020 Ligustilide protects PC12 cells from oxygen-glucose deprivation/reoxygenation-induced apoptosis via the LKB1-AMPK-mTOR signaling pathway. AMPK, LIG, LKB1, mTOR, OGD/R
15  2020 Lysosomal Dysregulation in the Murine AppNL-G-F/NL-G-F Model of Alzheimer's Disease. AD, LAMP1
16  2020 Molecular inflammation and oxidative stress are shared mechanisms involved in both myocardial infarction and periodontitis. AMI, AMI, pAMPK, TBARS
17  2020 Neuroprotective Role of Quercetin on Rotenone-Induced Toxicity in SH-SY5Y Cell Line Through Modulation of Apoptotic and Autophagic Pathways. MMP, PARP, ROS
18  2020 Organic anion transporters and PI3K-AKT-mTOR pathway mediate the synergistic anticancer effect of pemetrexed and rhein. Cl-Caspase3, MDC, NSCLC, OATs, PTX
19  2020 Phanginin R Induces Cytoprotective Autophagy via JNK/c-Jun Signaling Pathway in Non-Small Cell Lung Cancer A549 Cells. CQ, JNK, mTOR, NSCLC, PR
20  2020 Spermidine rescues the deregulated autophagic response to oxidative stress of osteoarthritic chondrocytes. ATG5, BECN-1, OA, OS, Spd
21  2020 Sprint and Strength Training Modulates Autophagy and Proteostasis in Aging Sprinters. CTRL, EX, UPR, VL
22  2020 Systemic inhibition of miR-451 increases fibrotic signaling and diminishes autophagic response to exacerbate renal damage in Tallyho/Jng mice. AMPKa, BECN1, CAB39, KIM1, miRs, MMP-9, mTOR, NGAL
23  2020 The effect of MEK1/2 inhibitors on cisplatin-induced acute kidney injury (AKI) and cancer growth in mice. AKI, ATN, CDK4, KRAS, NSCLC, PD-L1
24  2020 Toona sinensis modulates autophagy and cytokines in lipopolysaccharide-induced RAW 264.7 macrophages. IL, LPS, mTOR, TS
25  2020 Trans-10-hydroxy-2-decenoic acid protects against LPS-induced neuroinflammation through FOXO1-mediated activation of autophagy. 10-HDA, RJ
26  2020 Zinc protects chondrocytes from monosodium iodoacetate-induced damage by enhancing ATP and mitophagy. ATG5, MIA, OA, PINK1, PTEN
27  2019 AMPKalpha1 overexpression improves postoperative cognitive dysfunction in aged rats through AMPK-Sirt1 and autophagy signaling. AMPKalpha1, POCD
28  2019 An Autophagy Inducing Triterpene Saponin Derived from Aster koraiensis. ---
29  2019 Antimony, a novel nerve poison, triggers neuronal autophagic death via reactive oxygen species-mediated inhibition of the protein kinase B/mammalian target of rapamycin pathway. mTOR
30  2019 Autophagy precedes apoptosis during degeneration of the Kolliker's organ in the development of rat cochlea. ---
31  2019 Clinicopathologic characterization and abnormal autophagy of CSF1R-related leukoencephalopathy. CSF1R, HDLS
32  2019 EPHA3 enhances macrophage autophagy and apoptosis by disrupting the mTOR signaling pathway in mice with endometriosis. ATG3, Bcl-2, EPHA3, LC3-I, mTOR
33  2019 ERbeta promotes Abeta degradation via the modulation of autophagy. AD, CQ, DPN, ERbeta, SQSTM1
34  2019 Induction of Chemerin on Autophagy and Apoptosis in Dairy Cow Mammary Epithelial Cells. BMECs, CQ
35  2019 Induction of DDIT4 Impairs Autophagy Through Oxidative Stress in Dry Eye. DDIT4, SQSTM1
36  2019 Inhibition of PDE4 by FCPR16 induces AMPK-dependent autophagy and confers neuroprotection in SH-SY5Y cells and neurons exposed to MPP+-induced oxidative insult. AMPK, PD, ROS
37  2019 Lysosomal degradation of GMPPB is associated with limb-girdle muscular dystrophy type 2T. CMS, GMPPB, LGMD 2T
38  2019 Methylmercury-induced testis damage is associated with activation of oxidative stress and germ cell autophagy. CAT, GCs, GPx, mTOR, PI3K, ROS, SOD
39  2019 NF-kappaB/mTOR-mediated autophagy can regulate diquat-induced apoptosis. 3-MA, DA, DQ, MAPK, NAC, PFT-alpha, ROS
40  2019 Protective effects on age-related macular degeneration by activated autophagy induced by amyloid-beta in retinal pigment epithelial cells. AMD, RPE
41  2019 QiDiTangShen Granules Activate Renal Nutrient-Sensing Associated Autophagy in db/db Mice. DN, QDTS, UAE
42  2019 Sevoflurane Postconditioning Inhibits Autophagy Through Activation of the Extracellular Signal-Regulated Kinase Cascade, Alleviating Hypoxic-Ischemic Brain Injury in Neonatal Rats. HIBI, p-mTOR, SPC, TSC2
43  2019 SPARC induces phenotypic modulation of human brain vascular smooth muscle cells via AMPK/mTOR-mediated autophagy. ATG5, CC, HBVSMCs, SPARC
44  2019 Wheat Bran for Colon Cancer Prevention: The Synergy between Phytochemical Alkylresorcinol C21 and Intestinal Microbial Metabolite Butyrate. AR, CHOP, CRC, PARP, WGs
45  2019 [Association between autophagy and systemic juvenile idiopathic arthritis and related mechanism: a preliminary study]. MyD88, sJIA, STS-1
46  2019 [Effect of autophagy on N-methy-D-aspartate receptor and hyperalgesia in a rat model of neuropathic pain]. 3-MA, MWT, NMDA, NP, RAP, SD, TWL
47  2019 [The relationship between myocardial remodeling and endoplasmic reticulum stress and autophagy in rats with ischemic cardiomyopathy]. Beclin-I, GRP78, LC3-I
48  2018 A Mixture of Atropisomers Enhances Neutral Lipid Degradation in Mammalian Cells with Autophagy Induction. CE, CHO-K1, DPA1
49  2018 Alterations in mitochondrial fission, fusion, and mitophagic protein expression in the gastrocnemius of mice after a sciatic nerve transection. ULK1S555
50  2018 AMPK-dependent autophagy upregulation serves as a survival mechanism in response to Tumor Treating Fields (TTFields). AMPK, ATG7, CQ, ER, TTFields
51  2018 Bone marrow mesenchymal stem cells protect against n-hexane-induced neuropathy through beclin 1-independent inhibition of autophagy. BMSC, HD, mTOR, ULK1
52  2018 Cytochalasin E increased the sensitivity of human lung cancer A549 cells to bortezomib via inhibition of autophagy. CE, LAMP2
53  2018 Diquat-induced oxidative stress increases intestinal permeability, impairs mitochondrial function, and triggers mitophagy in piglets. ---
54  2018 Dot/Icm-Translocated Proteins Important for Biogenesis of the Coxiella burnetii-Containing Vacuole Identified by Screening of an Effector Mutant Sublibrary. CCV, INSeq, Tn
55  2018 Effects of Acute Cold Stress on Liver O-GlcNAcylation and Glycometabolism in Mice. AKT, ATP, Bax, Bcl-2, caspase-3, FDP, GSK3beta, O-GlcNAcylation, PA, PFKFB2
56  2018 Glycolysis inhibition via mTOR suppression is a key step in cardamonin-induced autophagy in SKOV3 cells. AMPK, HK, LDH, MDC
57  2018 Growth Inhibition of a Novel Iron Chelator, DpdtC, against Hepatoma Carcinoma Cell Lines Partly Attributed to Ferritinophagy-Mediated Lysosomal ROS Generation. DpdtC, NCOA4
58  2018 HMGB1-induced autophagy facilitates hepatic stellate cells activation: a new pathway in liver fibrosis. AVs, ERK, HBV, HMGB1, HSCs, JNK, MAPK, mTOR, RAGE, rHMGB1, TEM
59  2018 In vitro effect of Porphyromonas gingivalis combined with influenza A virus on respiratory epithelial cells. 3-MA, IAV, LC3-I
60  2018 Iron accumulation in senescent cells is coupled with impaired ferritinophagy and inhibition of ferroptosis. ---
61  2018 LPS challenge increased intestinal permeability, disrupted mitochondrial function and triggered mitophagy of piglets. GSH-Px, mt, SOD
62  2018 Lycium barbarum polysaccharide protects diabetic peripheral neuropathy by enhancing autophagy via mTOR/p70S6K inhibition in Streptozotocin-induced diabetic rats. DM, DPN, LBP, MBP, mTOR, p70S6K, SNAP, SNCV
63  2018 Mesenchymal Stem Cell-Derived Exosomes Ameliorated Diabetic Nephropathy by Autophagy Induction through the mTOR Signaling Pathway. 3-MA, DN, MSC, mTOR
64  2018 Novel SIRT1 inhibitor 15-deoxy-Delta12,14-prostaglandin J2 and its derivatives exhibit anticancer activity through apoptotic or autophagic cell death pathways in SKOV3 cells. Bcl-2, SIRT
65  2018 Optineurin promotes autophagosome formation by recruiting the autophagy-related Atg12-5-16L1 complex to phagophores containing the Wipi2 protein. Optn
66  2018 Regulation of autophagy factors by oxidative stress and cardiac enzymes imbalance during arsenic or/and copper induced cardiotoxicity in Gallus gallus. Atg4B, ATG5, CAT, GSH-Px, HDL-C, LC3-I, MDA, mTOR, PI3K, SOD, T-CHO
67  2018 Remote ischemic postconditioning protects the brain from focal ischemia/reperfusion injury by inhibiting autophagy through the mTOR/p70S6K pathway. I/R, MCAO, mTOR, p70S6K, RIPostC, TEM
68  2018 Renal ischemia/reperfusion-induced mitophagy protects against renal dysfunction via Drp1-dependent-pathway. IRI
69  2018 Signals in Stem Cell Differentiation on Fluorapatite-Modified Scaffolds. FA, PCL
70  2018 Sitagliptin enhances the neuroprotective effect of pregabalin against pentylenetetrazole-induced acute epileptogenesis in mice: Implication of oxidative, inflammatory, apoptotic and autophagy pathways. 3-NT, BDNF, CAT, GABA, GFAP, GLP-1, GPx, MDA, NF-kappaB, Nrf2, PTZ, SOD
71  2018 Skeletal muscle from aged American Quarter Horses shows impairments in mitochondrial biogenesis and expression of autophagy markers. LAMP2, TB
72  2018 The apoptosis in arsenic-induced oxidative stress is associated with autophagy in the testis tissues of chicken. ATG5, BW, CAT, mTOR, SOD
73  2018 The Effect of Fucoidan on Cellular Oxidative Stress and the CatD-Bax Signaling Axis in MN9D Cells Damaged by 1-Methyl-4-Phenypyridinium. Bax, FUC, PD, SOD
74  2018 The role of autophagy in the radiosensitivity of the radioresistant human nasopharyngeal carcinoma cell line CNE-2R. CCK-8, CDP, IR, RAPA
75  2018 Weaning disrupts intestinal antioxidant status, impairs intestinal barrier and mitochondrial function, and triggers mitophagy in piglets. GPx-1, GPX4, GSH-Px, LC3-I, MDA, MnSOD, mtDNA, PINK1, SOD
76  2017 A standardized extract of Butea monosperma (Lam.) flowers suppresses the IL-1beta-induced expression of IL-6 and matrix-metalloproteases by activating autophagy in human osteoarthritis chondrocytes. IL-6, MMP-3, mTOR, OA, qPCR
77  2017 Autophagy Inhibits Apoptosis Induced by agrocybe aegerita Lectin in Hepatocellular Carcinoma. AAL, AVOs, CQ, HCC
78  2017 Baicalein Induces Beclin 1- and Extracellular Signal-Regulated Kinase-Dependent Autophagy in Ovarian Cancer Cells. BA
79  2017 Curcumin induces apoptosis and protective autophagy in castration-resistant prostate cancer cells through iron chelation. CRPC, FAC, IRP1, MTT, TfR1
80  2017 Effect of 1,25(OH)2D3 on high glucose‑induced autophagy inhibition in peritoneum. HG, mTOR
81  2017 Effect of intestinal epithelial autophagy on bacterial translocation in severe acute pancreatitis. BT, CL-2, SAP, TJ, ZO-1
82  2017 Effects of probiotic Bacillus as a substitute for antibiotics on antioxidant capacity and intestinal autophagy of piglets. BA, JNK, Nrf2
83  2017 Fingolimod suppresses neuronal autophagy through the mTOR/p70S6K pathway and alleviates ischemic brain damage in mice. DMS, mTOR, S1P
84  2017 Hepatoprotective Effect of Curcumin on Hepatocellular Carcinoma Through Autophagic and Apoptic Pathways. AST, HCC, MDA, SOD, SQSTM1, TAA
85  2017 Hepatoprotective Effect of Curcumin on Hepatocellular Carcinoma Through Autophagic and Apoptic Pathways. AST, HCC, MDA, SOD, SQSTM1, TAA
86  2017 Hexane fraction of Pluchea indica root extract inhibits proliferation and induces autophagy in human glioblastoma cells. AVO, H-PIRE
87  2017 In vivo cardiomyocyte response to YTX- and AZA-1-induced damage: autophagy versus apoptosis. AZAs, YTX
88  2017 Induction of reactive oxygen species-stimulated distinctive autophagy by chelerythrine in non-small cell lung cancer cells. CHE, CQ, NSCLC, ROS
89  2017 Jianpi Qingchang decoction regulates intestinal motility of dextran sulfate sodium-induced colitis through reducing autophagy of interstitial cells of Cajal. DSS, ICC, IFN-gamma, IL, JQD, NF-kappaB, TNF-alpha
90  2017 Norditerpenoids and Dinorditerpenoids from the Seeds of Podocarpus nagi as Cytotoxic Agents and Autophagy Inducers. JNK
91  2017 Osimertinib induces autophagy and apoptosis via reactive oxygen species generation in non-small cell lung cancer cells. CAT, CQ, EGFR, NAC, NSCLC, OSI, ROS, Vita E
92  2017 Protective effect of autophagy on endoplasmic reticulum stress induced apoptosis of alveolar epithelial cells in rat models of COPD. 3-MA, AECs, CHOP, COPD, CQ, CS, ER, IOD, PERK, RI, SD, TdT
93  2017 Resveratrol ameliorates diet-induced dysregulation of lipid metabolism in zebrafish (Danio rerio). pAMPKalpha, PGC-1alpha, PPARgamma, RSV, SIRT1, TG
94  2017 Roflupram, a Phosphodiesterase 4 Inhibitior, Suppresses Inflammasome Activation through Autophagy in Microglial Cells. Abeta25-35, LPS, PDE4, ROF
95  2017 Supramolecular Peptide Nanofibers Engage Mechanisms of Autophagy in Antigen-Presenting Cells. APCs
96  2017 Tenovin-6 impairs autophagy by inhibiting autophagic flux. ---
97  2017 The Role of Netrin-1 in Improving Functional Recovery through Autophagy Stimulation Following Spinal Cord Injury in Rats. APs, CTSD, LAMP1, SCI, SQSTM1, TFEB
98  2017 Upregulated Autophagy in Sertoli Cells of Ethanol-Treated Rats Is Associated with Induction of Inducible Nitric Oxide Synthase (iNOS), Androgen Receptor Suppression and Germ Cell Apoptosis. 3-MA, ETRs, iNOS, LAMP-2, SCs, TFEB
99  2017 [Effect of Xinfeng Capsule on Beclin1/PI3K-AKT-mTOR of Adjuvant Arthritis Rats]. AA, AI, Atg5, 7,12, BW, CM, mTOR, PI3K, WM, XFC
100  2017 [Xinfeng Capsule improves pulmonary function of rats with adjuvant-induced arthritis via regulating the expressions of autophagy-related proteins]. AA, AI, ATG, IL, LEF, MC, NC, SD, TNF-alpha, XFC