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■ Abbreviation / Long Form : LPA / lysophosphatidic acid

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Total Number of Papers: 2946
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Abbreviation:   LPA  (>> Co-occurring Abbreviation)
Long Form:   lysophosphatidic acid
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No. Year Title Co-occurring Abbreviation
2022 A defective lysophosphatidic acid-autophagy axis increases miscarriage risk by restricting decidual macrophage residence. C-X-C, CLDN7, dMphi
2022 A novel role of lysophosphatidic acid (LPA) in human myeloma resistance to proteasome inhibitors. ER, MM, OXPHOS, PI
2022 A type IV Autotaxin inhibitor ameliorates acute liver injury and nonalcoholic steatohepatitis. ATX
2022 Activation of the ATX/LPA/LPARs axis induces a fibrotic response in skeletal muscle. CCN2, ECM, FAPs, IM, JNK, MDs
2022 Admission Lysophosphatidic Acid Is Related to Impaired Kidney Function in Acute Aortic Dissection: 2-Year Retrospective Follow-Up Study. AAD, AKI, CKD, LASSO
2022 AgRP neurons control feeding behaviour at cortical synapses via peripherally derived lysophospholipids. AgRP
2022 Altered MYO5B Function Underlies Microvillus Inclusion Disease: Opportunities for Intervention at a Cellular Level. MVID
2022 An Update on Sphingosine-1-Phosphate and Lysophosphatidic Acid Receptor Transcripts in Rodent Olfactory Mucosa. ACE2, S1P
2022 Anti-Inflammatory, Antioxidant, and Antifibrotic Effects of Gingival-Derived MSCs on Bleomycin-Induced Pulmonary Fibrosis in Mice. BALF, BL, CON, GMSCs, LPA1, MMP-9, MSC, NE
10  2022 Application of hybrid surface technology for improving sensitivity and peak shape of phosphorylated lipids such as phosphatidic acid and phosphatidylserine. CerP, HST, LPS, PA, PIP, PS, SPBP
11  2022 Arsenic trioxide activates yes-associated protein by lysophosphatidic acid metabolism to selectively induce apoptosis of vascular smooth muscle cells. ATO, ECs, m6A, VSMCs, YAP
12  2022 ATX/LPA axis regulates FAK activation, cell proliferation, apoptosis, and motility in human pancreatic cancer cells. ATX, FAK
13  2022 Autotaxin Activity in Chronic Subdural Hematoma: A Prospective Clinical Study. ATX, BT, CSDH, CSF
14  2022 Autotaxin Has a Negative Role in Systemic Inflammation. LPARs, LPS
15  2022 Autotaxin in Breast Cancer: Role, Epigenetic Regulation and Clinical Implications. ATX, ENPP2, lysoPLD
16  2022 Autotaxin signaling facilitates β cell dedifferentiation and dysfunction induced by Sirtuin 3 deficiency. HFD, LPC, T2D
17  2022 Autotaxin/Lysophosphatidic Acid Axis: From Bone Biology to Bone Disorders. ATX, LPC
18  2022 Berberine inhibits carcinogenesis through antagonizing the ATX-LPA-LPAR2-p38-leptin axis in a mouse hepatoma model. ATX, BBR, DEN, HCC, LPAR2
19  2022 Cell-trafficking impairment in disease-associated LPA6 missense mutants and a potential pharmacoperone therapy for autosomal recessive woolly hair/hypotrichosis. ARWH/HT, ER, GPCR
20  2022 Cholestatic Itch: Our Current Understanding of Pathophysiology and Treatments. IBAT, MRGPRX4
21  2022 Compensatory Upregulation of LPA2 and Activation of the PI3K-Akt Pathway Prevent LPA5-Dependent Loss of Intestinal Epithelial Cells in Intestinal Organoids. IECs, LPAR
22  2022 Crocin ameliorates atherosclerosis by promoting the reverse cholesterol transport and inhibiting the foam cell formation via regulating PPARγ/LXR-α. ABCA1, AS, CRO, HDL-C, HFD, LDL-C, LXRalpha, PPARgamma, TC/CE
23  2022 Current Knowledge on Mammalian Phospholipase A1, Brief History, Structures, Biochemical and Pathophysiological Roles. LysoPS, PA, PLA1, PS
24  2022 Decrease in serum levels of autotaxin in COVID-19 patients. ATX, COVID-19, LPAs, SARS-CoV-2
25  2022 Deep proteomic profiling unveils arylsulfatase A as a non-alcoholic steatohepatitis inducible hepatokine and regulator of glycemic control. ARSA, LPC, NASH
26  2022 Development and validation of a simple and rapid HILIC-MS/MS method for the quantification of low-abundant lysoglycerophospholipids in human plasma. cPA, dMRM, HILIC, HOMA-IR, LPG, LPI, Lyso-GPLs, LysoPAF, LysoPS
27  2022 Different Profiles of the Triad of Lysophosphatidylcholine, Lysophosphatidic Acid, and Autotaxin in Patients with Neuropathic Pain Diseases: a Preliminary Observational Study. ANCOVA, ATX, CSF, LPC, LSCS, pNfH
28  2022 Differential activation mechanisms of lipid GPCRs by lysophosphatidic acid and sphingosine 1-phosphate. GPCRs, LPA1, MS, S1P, S1P1
29  2022 Downregulation of connexin 43 potentiates amitriptyline-induced brain-derived neurotrophic factor expression in primary astrocytes through lysophosphatidic acid receptor1/3, Src, and extracellular signal-regulated kinase. BDNF, Cx43, ERK, siRNA
30  2022 Effect of BBT-877, a novel inhibitor of ATX, on a mouse model of type 1 diabetic nephropathy. ACR, ATX, DN, NGAL, STZ
31  2022 Effects of a lysophosphatidic acid receptor 1 antagonist on hypertensive renal injury in Dahl-Iwai salt-sensitive rats. ACE, DS
32  2022 Effects of lysophosphatidic acid (LPA) signaling via LPA receptors on cellular functions associated with ATP reduction in osteosarcoma cells treated with ethidium bromide. EtBr
33  2022 Efficacy Comparison of LPA2 Antagonist H2L5186303 and Agonist GRI977143 on Ovalbumin-Induced Allergic Asthma in BALB/c Mice. OVA
34  2022 Elevated level of lysophosphatidic acid among patients with HNF1B mutations and its role in RCAD syndrome: a multiomic study. ELISA, HNF1B, kd, MODY, PKD
35  2022 Endothelin-1 mediated glycosaminoglycan synthesizing gene expression involves NOX-dependent transactivation of the transforming growth factor-β receptor. C4ST-1, CHSY1, DPI, ET-1, GAG, GPCR, NOX, ROS, TGF
36  2022 Enhancement of P2X3 Receptor-Mediated Currents by Lysophosphatidic Acid in Rat Primary Sensory Neurons. alpha,beta-meATP, DRG, PKC
37  2022 ENPP1 deletion causes mouse osteoporosis via the MKK3/p38 MAPK/PCNA signaling pathway. ENPP1, KO, MAPK, Pobs, WT
38  2022 ENPP2 Promoter Methylation Correlates with Decreased Gene Expression in Breast Cancer: Implementation as a Liquid Biopsy Biomarker. ATX, BRCA, ccfDNA, DMCs, ENPP2, PA
39  2022 Evaluation of changes in egg yolk lipids during storage based on lipidomics through UPLC-MS/MS. DG, FA, GL, GP, PA, PR, SP, ST
40  2022 G-protein coupled receptor, PI3K and Rho signaling pathways regulate the cascades of Tau and amyloid-β in Alzheimer's disease. GPCRs, NFTs, TREM2
41  2022 Generalized resistance to pruritogen-induced scratching in the C3H/HeJ strain. C3H
42  2022 Gintonin stimulates dendritic growth in striatal neurons by activating Akt and CREB. BDNF, CREB
43  2022 Guanine inhibits the growth of human glioma and melanoma cell lines by interacting with GPR23. GBPs, GPRs, Gua, HGPRT
44  2022 Hepatocyte-Secreted Autotaxin Exacerbates Nonalcoholic Fatty Liver Disease Through Autocrine Inhibition of the PPARα/FGF21 Axis. FGF21, NAFLD
45  2022 Highly Selective Potentiometric Sensing of Biologically Relevant Pyrophosphate and Lysophosphatidic Acid Using N-Alkyl/Aryl Ammonium Resorcinarenes/Extended-Resorcinarenes as Ionophores. ISEs
46  2022 Host lysolipid differentially modulates virulence factor expression and antimicrobial susceptibility in Pseudomonas aeruginosa. OM
47  2022 Human monocytes differentiate into tumor-associated macrophages upon SKOV3 cells coculture and/or lysophosphatidic acid stimulation. TAMs
48  2022 Identification of lysophosphatidic acid in serum as a factor that promotes epithelial apical junctional complex organization. AJC, AJs, FBS
49  2022 Impact of pectin with various esterification degrees on the profiles of gut microbiota and serum metabolites. DSS, L13-H, PC, PE
50  2022 Inhibition of ChREBP ubiquitination via the ROS/Akt-dependent downregulation of Smurf2 contributes to lysophosphatidic acid-induced fibrosis in renal mesangial cells. ChREBP, DN, ROS, Smurf2
51  2022 Inhibition of the enzyme autotaxin reduces cortical excitability and ameliorates the outcome in stroke. ATX
52  2022 Investigation of novel ATX inhibitor metabolites by UHPLC-orbitrap-MS/MS and molecular docking studies. LPC
53  2022 Joint Damage and Neuropathic Pain in Rats Treated With Lysophosphatidic Acid. ---
54  2022 KAI1/CD82 gene and autotaxin-lysophosphatidic acid axis in gastrointestinal cancers. ATX, lysoPLD
55  2022 Lateral access mechanism of LPA receptor probed by molecular dynamics simulation. GPCR, MD, MSM, TMs
56  2022 Lipid Metabolism in Cancer: The Role of Acylglycerolphosphate Acyltransferases (AGPATs). AGPATs, CGL, FA, LDs, LPAATs, PA, TAG
57  2022 Lipid phosphate phosphatase 3 in smooth muscle cells regulates angiotensin II-induced abdominal aortic aneurysm formation. Ang II, LPP3, NF-kappaB, SMC
58  2022 Lipidomic analysis of differently prepared platelet concentrates in additive solution during storage. BC, LP, LPC, PAS, PC, SDA
59  2022 LPA maintains innate antiviral immunity in a pro-active state via STK38L-mediated IRF3 Ser303 phosphorylation. S1P, SRF, STK38L
60  2022 LPA suppresses T cell function by altering the cytoskeleton and disrupting immune synapse formation. IS, TCR
61  2022 LPA/LPAR1 signaling induces PGAM1 expression via AKT/mTOR/HIF-1α pathway and increases aerobic glycolysis, contributing to keratinocyte proliferation. IMQ
62  2022 LPA2 Contributes to Vascular Endothelium Homeostasis and Cardiac Remodeling After Myocardial Infarction. Lpar2-KO, MI
63  2022 LPA2 promotes neuronal differentiation and neurite formation in neocortical development. LPARs
64  2022 LPA3 is a precise therapeutic target and potential biomarker for ovarian cancer. LPARs
65  2022 LPA6-RhoA signals regulate junctional complexes for polarity and morphology establishment of maturation stage ameloblasts. F-actin, LPA6, M-ABs, ZO-1
66  2022 Lpar1-Mediated Effects in Endothelial Progenitor Cells are Crucial for Lung Repair in ARDS/ALI. ARDS/ALI, EPCs, LPS
67  2022 LPAR2 correlated with different prognosis and immune cell infiltration in head and neck squamous cell carcinoma and kidney renal clear cell carcinoma. GEO, GEPIA, HNSC, HPA, KIRC, KM plotter, LPAR2, TIMER
68  2022 LPAR2-mediated action promotes human renal cell carcinoma via MAPK/NF-κB signaling to regulate cytokine network. RC
69  2022 Lysophosphatidic acid as a CSF lipid in posthemorrhagic hydrocephalus that drives CSF accumulation via TRPV4-induced hyperactivation of NKCC1. CSF, IVH, SAH, TRPV4
70  2022 Lysophosphatidic Acid Improves Human Sperm Motility by Enhancing Glycolysis and Activating L-Type Calcium Channels. BSA
71  2022 Lysophosphatidic Acid Induced Apoptosis, DNA Damage, and Oxidative Stress in Spinal Cord Neurons by Upregulating LPA4/LPA6 Receptors. LSS, SRF-RE
72  2022 Lysophosphatidic Acid Is a Proinflammatory Stimulus of Renal Tubular Epithelial Cells. CKD
73  2022 Lysophosphatidic Acid May Be a Novel Biomarker for Early Acute Aortic Dissection. AAD
74  2022 Lysophosphatidic acid production from lysophosphatidylcholine by lysophospholipase D activity of autotaxin in plasma of women with normal and adverse pregnancies. LPC, lysoPLD
75  2022 Lysophosphatidic Acid Promotes Epithelial-Mesenchymal Transition in Kidney Epithelial Cells via the LPAR1/MAPK-AKT/KLF5 Signaling Pathway in Diabetic Nephropathy. alpha-SMA, DN, EMT, ERK, JNK, KLF5
76  2022 Lysophosphatidic Acid Promotes the Expansion of Cancer Stem Cells via TRPC3 Channels in Triple-Negative Breast Cancer. BCSCs, TNBC, TRPC3
77  2022 Lysophosphatidic acid protects cervical cancer HeLa cells from apoptosis induced by doxorubicin hydrochloride. DOX
78  2022 Lysophosphatidic Acid Receptor 3 Promotes Mitochondrial Homeostasis against Oxidative Stress: Potential Therapeutic Approaches for Hutchinson-Gilford Progeria Syndrome. HGPS, OXPHOS, ROS
79  2022 Lysophosphatidic Acid Receptor 3 Suppress Neutrophil Extracellular Traps Production and Thrombosis During Sepsis. FIB, LPA3, LPS, NETs, OMPT, PT, WT
80  2022 Lysophosphatidic Acid Receptor 5 (LPA5) Knockout Ameliorates the Neuroinflammatory Response In Vivo and Modifies the Inflammatory and Metabolic Landscape of Primary Microglia In Vitro. LPA5
81  2022 Lysophosphatidic acid receptor1/3 antagonist inhibits the activation of satellite glial cells and reduces acute nociceptive responses. DRG, SGCs
82  2022 Lysophosphatidic Acid Signaling and microRNAs: New Roles in Various Cancers. miRNAs
83  2022 Lysophosphatidic acid signaling via LPA6 : A negative modulator of developmental oligodendrocyte maturation. CNS, MS, OLGs
84  2022 Lysophosphatidic acid stimulates pericyte migration via LPA receptor 1. LPARs
85  2022 Lysophosphatidic acid supports the development of vitrified ovarian follicles by decreasing the incidence of cell death: An experimental study. ---
86  2022 Lysophosphatidic acid, ceramide 1-phosphate and sphingosine 1-phosphate in peripheral blood of patients with idiopathic pulmonary fibrosis. C1P, IPF, S1P, VC
87  2022 Lysophosphatidic acid-induced amphiregulin secretion by cancer-associated fibroblasts augments cancer cell invasion. AREG, CAFs, NFs, YAP, ZEB1
88  2022 Mesenteric Adipose Tissue Contributes to Intestinal Fibrosis in Crohn's Disease Through the ATX-LPA Axis. ATX, CD, DNBS, MAT
89  2022 Molecular Pharmacology and Novel Potential Therapeutic Applications of Fingolimod. AD, cPLA2alpha, PD, PP2A, S1PRs, TRMP7
90  2022 Mucin 1 aggravates synovitis and joint damage of rheumatoid arthritis by regulating inflammation and aggression of fibroblast-like synoviocytes. GTPases, MUC1, PCR, RA
91  2022 O-GlcNAcylation regulates lysophosphatidic acid-induced cell migration by regulating ERM family proteins. ---
92  2022 Pain-like behavior in the collagen antibody-induced arthritis model is regulated by lysophosphatidic acid and activation of satellite glia cells. CAIA, DRG, RA, SGCs
93  2022 Phase 2 trial design of BMS-986278, a lysophosphatidic acid receptor 1 (LPA1) antagonist, in patients with idiopathic pulmonary fibrosis (IPF) or progressive fibrotic interstitial lung disease (PF-ILD). IPF, LPA1, PF-ILD
94  2022 Plant lipid phosphate phosphatases: current advances and future outlooks. LPPs
95  2022 Plasma membrane phospholipid phosphatase-related proteins as pleiotropic regulators of neuron growth and excitability. PLPPRs
96  2022 Potentiation of ASIC currents by lysophosphatidic acid in rat dorsal root ganglion neurons. ASICs, DRG, PKC
97  2022 Preclinical detection of lysophosphatidic acid: A new window for ovarian cancer diagnostics. ---
98  2022 Red Blood Cell-Conditioned Media from Non-Alcoholic Fatty Liver Disease Patients Contain Increased MCP1 and Induce TNF-α Release. NAFLD, S1P
99  2022 Roles of Autotaxin/Autotaxin-Lysophosphatidic Acid Axis in the Initiation and Progression of Liver Cancer. ATX
100  2022 Serum autotaxin levels in chronic disease and acute exacerbation of fibrosing interstitial lung disease. AE-IPF, ATX, ILD