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■ Abbreviation / Long Form : MCP / membrane cofactor protein

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Total Number of Papers: 249
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Abbreviation:   MCP  (>> Co-occurring Abbreviation)
Long Form:   membrane cofactor protein
 Abbreviation Variation
 Long Form Variation
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No. Year Title Co-occurring Abbreviation
2019 CD46 knock-out using CRISPR/Cas9 editing of hTERT immortalized human cells modulates complement activation. ---
2019 Endothelial lesion and complement activation in patients with Scleroderma Renal Crisis. SRC, SSc, TMA
2019 Molecular engineering of an efficient four-domain DAF-MCP chimera reveals the presence of functional modularity in RCA proteins. CCP, CFA, DAA, DAF, RCA
2018 Alternative pathway activation due to low level of complement factor H in primary antiphospholipid syndrome. APS, CRF, FH, Other CTD, PAPS
2018 Consequences of dysregulated complement regulators on red blood cells. CR1, RBCs
2017 Case report - atypical hemolytic uremic syndrome triggered by influenza B. aHUS
2017 Murine systemic thrombophilia and hemolytic uremic syndrome from a factor H point mutation. FH, TMA
2016 Complete remission of thrombotic microangiopathy after treatment with eculizumab in a patient with non-Shiga toxin-associated bacterial enteritis: A case report. aHUS, ICU, PE
2016 Depression of Complement Regulatory Factors in Rat and Human Renal Grafts Is Associated with the Progress of Acute T-Cell Mediated Rejection. ATCMR, Crry, qRT-PCR
10  2016 Proteomic characterization of macro-, micro- and nano-extracellular vesicles derived from the same first trimester placenta: relevance for feto-maternal communication. DAF, EVs, PBRF, RPS4
11  2016 Xenotransplanted Pig Sertoli Cells Inhibit Both the Alternative and Classical Pathways of Complement-Mediated Cell Lysis While Pig Islets Are Killed. DAF, MAC, NPIs, NPSCs, SCs
12  2015 Complement regulator CD46: genetic variants and disease associations. aHUS
13  2015 Mapping interactions between complement C3 and regulators using mutations in atypical hemolytic uremic syndrome. aHUS, CR1, FH
14  2015 Structural insights on complement activation. AP, CR1, DAF, FH, MG1, TED
15  2015 The molecular and structural bases for the association of complement C3 mutations with atypical hemolytic uremic syndrome. aHUS
16  2015 [Atypical HUS caused by complement-related abnormalities]. aHUS, CFB, CFH, CFI, DGKE, STEC, THBD
17  2015 [Genetics of aHUS and transplant recurrence]. aHUS, DGKE, HUS
18  2014 Adult-onset eculizumab-resistant hemolytic uremic syndrome associated with cobalamin C deficiency. HIV, HUS
19  2014 Evaluation of the markers of inflammation in the umbilical cord blood of newborns of mothers with thrombophilia. DAF
20  2014 New functional and structural insights from updated mutational databases for complement factor H, Factor I, membrane cofactor protein and C3. AMD, CFH, CFI
21  2014 Tissue-specific deletion of Crry from mouse proximal tubular epithelial cells increases susceptibility to renal ischemia-reperfusion injury. mAb
22  2013 Atypical hemolytic uremic syndrome with MCP mutations preceded by respiratory infection. HUS, PE
23  2013 Complement activation by heme as a secondary hit for atypical hemolytic uremic syndrome. aHUS, AP, DAF, FH
24  2013 Complement C3 and decay-accelerating factor expression levels are modulated by human chorionic gonadotropin in endometrial compartments during the implantation window. DAF, hCG, mRNA, RT-PCR
25  2013 Complement factor H mutation associated with membranoproliferative glomerulonephritis with transformation to atypical haemolytic uraemic syndrome. aHUS
26  2013 Complement genes strongly predict recurrence and graft outcome in adult renal transplant recipients with atypical hemolytic and uremic syndrome. aHUS
27  2013 Genetics and outcome of atypical hemolytic uremic syndrome: a nationwide French series comparing children and adults. aHUS
28  2013 Rapid recovery of membrane cofactor protein (MCP; CD46) associated atypical haemolytic uraemic syndrome with plasma exchange. aHUS
29  2013 The measles virus hemagglutinin beta-propeller head beta4-beta5 hydrophobic groove governs functional interactions with nectin-4 and CD46 but not those with the signaling lymphocytic activation molecule. MV, PVRL4, SLAM
30  2013 [Pathophysiology of atypical hemolytic uremic syndrome. Ten years of progress, from laboratory to patient]. aHUS, DGKE, HUS
31  2012 A prevalent C3 mutation in aHUS patients causes a direct C3 convertase gain of function. aHUS, FH, GEnCs
32  2012 Acquired and genetic complement abnormalities play a critical role in dense deposit disease and other C3 glomerulopathies. ---
33  2012 Atypical hemolytic uremic syndrome in children: complement mutations and clinical characteristics. aHUS, CFH, THBD
34  2012 Complement inhibitory proteins expression in placentas of thrombophilic women. DAF
35  2012 Eculizumab in the treatment of atypical hemolytic uremic syndrome in infants. CFH, eGFR, TMA
36  2012 Expression and significance of leukocyte membrane cofactor protein transcript in systemic lupus erythematosus. CIC, SLE
37  2012 The genetics of the alternative pathway of complement in the pathogenesis of HELLP syndrome. CFB, CFH, CFI
38  2011 A case-control study of membrane cofactor protein mutations in two populations of patients with early pregnancy loss. FL, RM
39  2011 aHUS caused by complement dysregulation: new therapies on the horizon. aHUS, CFB, CFH, CFHR, CFI, THBD
40  2011 Atypical hemolytic uremic syndrome. aHUS, HUS
41  2011 Mutations in complement regulatory proteins predispose to preeclampsia: a genetic analysis of the PROMISSE cohort. APL Ab, CFH, CFI, SLE
42  2011 [Atypical hemolytic-uremic syndrome related to abnormalities within the complement system]. aHUS, CFH, HUS, TMA
43  2010 Assessment of the transcription levels for the complement activation control system in eutopic endometrium in women with two or more consecutive miscarriages of unknown etiology. DAF, HB-EGF
44  2010 Domain swapping reveals complement control protein modules critical for imparting cofactor and decay-accelerating activities in vaccinia virus complement control protein. DAA, VCP
45  2010 Genetic disorders in complement (regulating) genes in patients with atypical haemolytic uraemic syndrome (aHUS). aHUS, aHUS, FB, IF
46  2010 Human C3 mutation reveals a mechanism of dense deposit disease pathogenesis and provides insights into complement activation and regulation. AP, DAF, DDD, FH, FI
47  2010 Relative role of genetic complement abnormalities in sporadic and familial aHUS and their impact on clinical phenotype. aHUS, CFH, HUS
48  2010 Screening of complement inhibitors: shielded baculoviruses increase the safety and efficacy of gene delivery. AST, C4BP, DAF, FH, VSV-G
49  2009 A novel mutation in the complement regulator clusterin in recurrent hemolytic uremic syndrome. HUS
50  2009 Cooperation of decay-accelerating factor and membrane cofactor protein in regulating survival of human cervical cancer cells. CDC, DAF, shRNA
51  2009 Successful renal transplantation in a patient with atypical hemolytic uremic syndrome carrying mutations in both factor I and MCP. aHUS, CFH
52  2008 Complement and the atypical hemolytic uremic syndrome in children. aHUS, ESRD
53  2008 Complement mutation-associated de novo thrombotic microangiopathy following kidney transplantation. aHUS, TMA
54  2008 Inherited deficiency of membrane cofactor protein expression and varying manifestations of recurrent atypical hemolytic uremic syndrome in a sibling pair. aHUS, CFH
55  2008 Membrane cofactor protein mutations in atypical hemolytic uremic syndrome (aHUS), fatal Stx-HUS, C3 glomerulonephritis, and the HELLP syndrome. aHUS, aHUS, HUS, Stx
56  2008 Non-small cell lung cancer cells produce a functional set of complement factor I and its soluble cofactors. C4BP, FI, NSCLC
57  2008 [Co-expression and synergic effect of human complement regulatory proteins DAF and MCP]. DAF, hCRPs
58  2007 A mutation in factor I that is associated with atypical hemolytic uremic syndrome does not affect the function of factor I in complement regulation. aHUS, FH, FI
59  2007 Complete factor H deficiency-associated atypical hemolytic uremic syndrome in a neonate. aHUS, FH, IF
60  2007 Differential impact of complement mutations on clinical characteristics in atypical hemolytic uremic syndrome. aHUS, IF
61  2007 Implications of the initial mutations in membrane cofactor protein (MCP; CD46) leading to atypical hemolytic uremic syndrome. CFH, IF
62  2007 Modeling how CD46 deficiency predisposes to atypical hemolytic uremic syndrome. CHO, DAF
63  2007 Primary glomerulonephritis with isolated C3 deposits: a new entity which shares common genetic risk factors with haemolytic uraemic syndrome. C3NeF, CAP, glomerulonephritis C3, HUS, MPGN
64  2007 The decay accelerating factor mutation I197V found in hemolytic uraemic syndrome does not impair complement regulation. aHUS, CFH, DAF, IF, RCA
65  2007 The interactive Factor H-atypical hemolytic uremic syndrome mutation database and website: update and integration of membrane cofactor protein and Factor I mutations with structural models. aHUS, AMD, AP, FH, FI, MPGN, SCR
66  2007 Unusual clinical severity of complement membrane cofactor protein-associated hemolytic-uremic syndrome and uniparental isodisomy. CFH, IF
67  2007 [Hemolytic uremic syndrome]. CFH, HUS, non-Stx-HUS, Stx
68  2006 A user's guide to the interactive Web database of factor H-associated hemolytic uremic syndrome. aHUS
69  2006 Atypical haemolytic uraemic syndrome. CFH, HUS, IF
70  2006 Expression of complement system regulatory molecules in the endometrium of normal ovulatory and hyperstimulated women correlate with menstrual cycle phase. DAF
71  2006 Genetic and functional analyses of membrane cofactor protein (CD46) mutations in atypical hemolytic uremic syndrome. aHUS, HUS
72  2006 Genetics of HUS: the impact of MCP, CFH, and IF mutations on clinical presentation, response to treatment, and outcome. CFH, HUS, IF, non-Stx-HUS
73  2006 Insights into hemolytic uremic syndrome: segregation of three independent predisposition factors in a large, multiple affected pedigree. ---
74  2006 Membrane cofactor protein and factor I: mutations and transplantation. CFH, IF
75  2006 Outcome of renal transplantation in patients with non-Shiga toxin-associated hemolytic uremic syndrome: prognostic significance of genetic background. IF, non-Stx-HUS
76  2006 [Clinical aspects of the complement system]. ---
77  2005 Atypical haemolytic uraemic syndrome and mutations in complement regulator genes. FH, HUS, TMA
78  2005 Complement regulatory proteins are incorporated into lentiviral vectors and protect particles against complement inactivation. CRPs, DAF
79  2005 Do poor-prognosis breast tumours express membrane cofactor proteins (CD46)? ---
80  2005 Effect of IL-4 on altered expression of complement activation regulators in rat pancreatic cells during severe acute pancreatitis. DAF, SAP
81  2005 Evolutionary history of orthopoxvirus proteins similar to human complement regulators. CR1, DAF, FH, IMP, RCA, SCRs, SPICE, VCP
82  2005 Helicobacter pylori eradication decreases the expression of glycosylphosphatidylinositol-anchored complement regulators, decay-accelerating factor and homologous restriction factor 20, in human gastric epithelium. DAF, GPI, H. pylori, HRF20
83  2005 Hemolytic uremic syndrome: an example of insufficient complement regulation on self-tissue. aHUS, HUS
84  2005 Mutations in complement factor I predispose to development of atypical hemolytic uremic syndrome. CFH, HUS, IF
85  2005 Porcine complement regulators protect aortic smooth muscle cells poorly against human complement-induced lysis and proliferation: consequences for xenotransplantation. IL, MAC, PAEC, PASMC
86  2005 Targeted and restricted complement activation on acrosome-reacted spermatozoa. CRP, IAM
87  2005 The development of atypical haemolytic-uraemic syndrome is influenced by susceptibility factors in factor H and membrane cofactor protein: evidence from two independent cohorts. aHUS, CFH, IF
88  2005 The effect of complement regulatory protein expression on pig endothelial cells to porcine endogenous retrovirus lyses by human sera. CRP, DAF, pEC, PERV, PERV-B
89  2004 Complement inhibitor membrane cofactor protein (MCP; CD46) is constitutively shed from cancer cell membranes in vesicles and converted by a metalloproteinase to a functionally active soluble form. ---
90  2004 Complement regulatory proteins are expressed at low levels in embryonic human, wild type and transgenic porcine neural tissue. DAF
91  2004 Human oligodendroglial cells express low levels of C1 inhibitor and membrane cofactor protein mRNAs. ---
92  2004 Inherited dysregulation of the complement system. ---
93  2004 Rat membrane cofactor protein (MCP; CD46) is expressed only in the acrosome of developing and mature spermatozoa and mediates binding to immobilized activated C3. ---
94  2004 The identification of an adenovirus receptor by using affinity capture and mass spectrometry. VOPBA
95  2003 Familial haemolytic uraemic syndrome and an MCP mutation. D-HUS, PCR-SSCP
96  2003 Mutations in human complement regulator, membrane cofactor protein (CD46), predispose to development of familial hemolytic uremic syndrome. HUS
97  2003 Obstacles to cancer immunotherapy: expression of membrane complement regulatory proteins (mCRPs) in tumors. CR1, DAF, mAbs, MAC, mCRPs
98  2002 Adenovirus-mediated gene transfer of triple human complement regulating proteins (DAF, MCP and CD59) in the xenogeneic porcine-to-human transplantation model. Part I: in vitro assays using porcine aortic endothelial cells. DAF, hCRPs, MOI, PAE, PAECs, RT-PCR
99  2002 Characterization of human membrane cofactor protein (MCP; CD46) on spermatozoa. Tg
100  2002 Cutting edge: inhibiting measles virus infection but promoting reproduction: an explanation for splicing and tissue-specific expression of CD46. CCPs