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■ Abbreviation / Long Form : MEP / methylerythritol phosphate

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Total Number of Papers: 419
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Abbreviation:   MEP  (>> Co-occurring Abbreviation)
Long Form:   methylerythritol phosphate
 Abbreviation Variation
 Long Form Variation
 Pair(Abbreviation/Long Form) Variation
No. Year Title Co-occurring Abbreviation
2019 Comparative transcriptomic analysis reveal the regulation mechanism underlying MeJA-induced accumulation of alkaloids in Dendrobium officinale. MeJA, MVA
2019 Dynamic changes in ABA content in water-stressed Populus nigra: effects on carbon fixation and soluble carbohydrates. ABA, ABA-GE, WUEint, WW
2019 Engineering triterpene metabolism in the oilseed of Arabidopsis thaliana. DXS, FPS, MVA
2019 Exploring natural biodiversity to expand access to microbial terpene synthesis. DMAPP, IPK, IPP, MVA
2019 Increased sesqui- and triterpene production by co-expression of HMG-CoA reductase and biotin carboxyl carrier protein in tobacco (Nicotiana benthamiana). BCCP, DMAPP, IPP, MVA, tHMGR
2019 Metabolic Engineering of Bacillus subtilis Toward Taxadiene Biosynthesis as the First Committed Step for Taxol Production. FPP, GGPP, GRAS, TXS
2019 Phytol metabolism in plants. GGR
2019 Plant hormone effects on isoprene emission from tropical tree in Ficus septica. CK, IspS, JA
2019 SEED CAROTENOID DEFICIENT Functions in Isoprenoid Biosynthesis via the Plastid MEP Pathway. HMBPP, MEcPP, SCD
10  2019 Terpenes and isoprenoids: a wealth of compounds for global use. DMAPP, IPP, MVA
11  2019 The plastidial metabolite 2-C-methyl-D-erythritol-2,4-cyclodiphosphate modulates defense responses against aphids. JA, MEcPP, SA
12  2019 Transcriptomic responses to grazing reveal the metabolic pathway leading to the biosynthesis of domoic acid and highlight different defense strategies in diatoms. DA, GPP, MEV
13  2019 [Integrating balanced mevalonate pathway into chromosome for improving lycopene production in Escherichia coli]. DMAPP, IPP, MVA
14  2018 A high-throughput screening campaign to identify inhibitors of DXP reductoisomerase (IspC) and MEP cytidylyltransferase (IspD). HTS, IspC
15  2018 A role for beta,beta-xanthophylls in Arabidopsis UV-B photoprotection. ---
16  2018 A single nucleotide mutation of IspE gene participating in the MEP pathway for isoprenoid biosynthesis causes green-revertible yellow leaf phenotype in rice. MVA
17  2018 A single nucleotide mutation of IspF gene involved in the MEP pathway for isoprenoid biosynthesis causes yellow-green leaf phenotype in rice. DMAPP, IPP
18  2018 Alternative Carbon Sources for Isoprene Emission. ---
19  2018 Apicoplast Metabolism: Parasite's Achilles' Heel. ---
20  2018 Biological Studies and Target Engagement of the 2- C-Methyl-d-Erythritol 4-Phosphate Cytidylyltransferase (IspD)-Targeting Antimalarial Agent (1 R,3 S)-MMV008138 and Analogs. CDP-ME, CTP, DMAPP, FOS, IPP
21  2018 Characterization of Plant Volatiles Reveals Distinct Metabolic Profiles and Pathways among 12 Brassicaceae Vegetables. GC-HRMS, GLs, GLVs, HS-SPME, ITCs, PCA, VOCs
22  2018 Contribution of isopentenyl phosphate to plant terpenoid metabolism. IP, IPKs, IPP, MPD, MVA, PMK
23  2018 Crystal structure of IspF from Bacillus subtilis and absence of protein complex assembly amongst IspD/IspE/IspF enzymes in the MEP pathway. CDPME2P, CMP, MEcDP
24  2018 De novo transcriptome sequencing and metabolite profiling analyses reveal the complex metabolic genes involved in the terpenoid biosynthesis in Blue Anise Sage (Salvia guaranitica L.). ---
25  2018 Enhancing carotenoid biosynthesis in rice endosperm by metabolic engineering. IPP, MVA, VAD
26  2018 Growth medium-dependent antimicrobial activity of early stage MEP pathway inhibitors. BAP, DXP
27  2018 Improved fruit alpha-tocopherol, carotenoid, squalene and phytosterol contents through manipulation of Brassica juncea 3-HYDROXY-3-METHYLGLUTARYL-COA SYNTHASE1 in transgenic tomato. HMGS, MVA, OEs, WT
28  2018 Isolation and characterization of 4-hydroxy-3-methylbut-2-enyl diphosphate reductase gene from Botryococcus braunii, race B. BbHDR, HDR
29  2018 Metabolomics Analysis Reveals that Ethylene and Methyl Jasmonate Regulate Different Branch Pathways to Promote the Accumulation of Terpenoid Indole Alkaloids in Catharanthus roseus. LC, MeJA, MVA, TIAs
30  2018 Modular pathway engineering of Bacillus subtilis to promote de novo biosynthesis of menaquinone-7. SA
31  2018 Molecular Characterization of the 1-Deoxy-D-Xylulose 5-Phosphate Synthase Gene Family in Artemisia annua. DXS
32  2018 Molecular regulatory mechanism of isoprene emission under short-term drought stress in the tropical tree Ficus septica. APX1, Cu-ZnSOD2, IspS, Mn-SOD1, POD2, ROS
33  2018 Patchoulol Production with Metabolically Engineered Corynebacterium glutamicum. ---
34  2018 Phototrophic production of heterologous diterpenoids and a hydroxy-functionalized derivative from Chlamydomonas reinhardtii. CDM
35  2018 Role of Mitochondria in Regulating Lutein and Chlorophyll Biosynthesis in Chlorella pyrenoidosa under Heterotrophic Conditions. HMBPP, ME-Cpp, mRET, PEPCK, SHAM
36  2018 Rust Infection of Black Poplar Trees Reduces Photosynthesis but Does Not Affect Isoprene Biosynthesis or Emission. ---
37  2018 Shedding light on the methylerythritol phosphate (MEP)-pathway: long hypocotyl 5 (HY5)/phytochrome-interacting factors (PIFs) transcription factors modulating key limiting steps. HY5, PIFs
38  2018 Sodorifen Biosynthesis in the Rhizobacterium Serratia plymuthica Involves Methylation and Cyclization of MEP-Derived Farnesyl Pyrophosphate by a SAM-Dependent C-Methyltransferase. FPP, SAM
39  2018 Structural characterization of 1-deoxy-D-xylulose 5-phosphate Reductoisomerase from Vibrio vulnificus. Dxp, Dxr
40  2018 Structural modeling identifies Plasmodium vivax 4-diphosphocytidyl-2C-methyl-d-erythritol kinase (IspE) as a plausible new antimalarial drug target. GHMP, IspE, MAVK, PvIspE
41  2018 Suppression of Drug Resistance Reveals a Genetic Mechanism of Metabolic Plasticity in Malaria Parasites. FSM, HAD, PF3D7_1226300, PFK9
42  2018 Synthesis and Evaluation of Fluoroalkyl Phosphonyl Analogues of 2- C-Methylerythritol Phosphate as Substrates and Inhibitors of IspD from Human Pathogens. DMADP, IDP
43  2018 Synthesis and Kinetic evaluation of an azido analogue of methylerythritol phosphate: a Novel Inhibitor of E. coli YgbP/IspD. ---
44  2018 Systematic overexpression study to find target enzymes enhancing production of terpenes in Synechocystis PCC 6803, using isoprene as a model compound. MVA
45  2018 The MEP pathway in Babesia orientalis apicoplast, a potential target for anti-babesiosis drug development. ORFs
46  2018 The Methylerythritol Phosphate Pathway: Promising Drug Targets in the Fight against Tuberculosis. DMAPP, DXS, IPP, Mtb, TB
47  2018 Toward Understanding the Chemistry and Biology of 1-Deoxy-d-xylulose 5-Phosphate (DXP) Synthase: A Unique Antimicrobial Target at the Heart of Bacterial Metabolism. d-GAP, DXP, PLP, ThDP
48  2018 Tracing the biosynthetic origin of limonoids and their functional groups through stable isotope labeling and inhibition in neem tree (Azadirachta indica) cell suspension. DXS, HMGR, MVA, UPLC
49  2018 Virus-Induced Silencing of Key Genes Leads to Differential Impact on Withanolide Biosynthesis in the Medicinal Plant, Withania somnifera. MVA, TRV, VIGS
50  2017 Characterization of 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (IspG) from Plasmodium vivax and it's potential as an antimalarial drug target. ---
51  2017 Co-expression of peppermint geranyl diphosphate synthase small subunit enhances monoterpene production in transgenic tobacco plants. GGPP, GGPPS3, GPS, MpGPS.SSU, SlDXS
52  2017 Combining Gal4p-mediated expression enhancement and directed evolution of isoprene synthase to improve isoprene production in Saccharomyces cerevisiae. IspS, MVA
53  2017 Comparative Analysis of Tocopherol Biosynthesis Genes and Its Transcriptional Regulation in Soybean Seeds. DXR, gamma-TMT3, GGDR, SK, T-toc, TAT, TC
54  2017 Comparative glandular trichome transcriptome-based gene characterization reveals reasons for differential (-)-menthol biosynthesis in Mentha species. GT, MD, MVA, TPSs
55  2017 Comparative transcriptome analysis reveals candidate genes for the biosynthesis of natural insecticide in Tanacetum cinerariifolium. ---
56  2017 Complex interplays between phytosterols and plastid development. FPS, IPP, MVA
57  2017 Comprehensive assessment of the genes involved in withanolide biosynthesis from Withania somnifera: chemotype-specific and elicitor-responsive expression. ER, MJ, MVA, SA
58  2017 Computational analysis, structural modeling and ligand binding site prediction of Plasmodium falciparum 1-deoxy-d-xylulose-5-phosphate synthase. ---
59  2017 De novo post-illumination monoterpene burst in Quercus ilex (holm oak). PiCO2B, PiMB
60  2017 Designing a New Entry Point into Isoprenoid Metabolism by Exploiting Fructose-6-Phosphate Aldolase Side Reactivity of Escherichia coli. DXP
61  2017 Direct Conversion of CO2 to alpha-Farnesene Using Metabolically Engineered Synechococcus elongatus PCC 7942. FS
62  2017 Dissecting the role of isoprene and stress-related hormones (ABA and ethylene) in Populus nigra exposed to unequal root zone water stress. ABA, WW
63  2017 Dynamics of Monoterpene Formation in Spike Lavender Plants. DMAPP, HMGR, IPP, MVA
64  2017 Enhanced performance of the methylerythritol phosphate pathway by manipulation of redox reactions relevant to IspC, IspG, and IspH. DMAPP, IPP, ME
65  2017 Exceptionally high percentage of IPP synthesis by Ginkgo biloba IspH is mainly due to Phe residue in the active site. DMAPP, HMBPP, IPP
66  2017 Exploration of the 1-deoxy-d-xylulose 5-phosphate synthases suitable for the creation of a robust isoprenoid biosynthesis system. BsDXS, DMAPP, DXS, PaDXS
67  2017 Genome-wide identification and characterization of genes involved in carotenoid metabolic in three stages of grapevine fruit development. MVA
68  2017 Identification and cytochemical immunolocalization of acetyl-CoA acetyltransferase involved in the terpenoid mevalonate pathway in Euphorbia helioscopia laticifers. AACT, DMAPP, ER, IPP, MVA
69  2017 Interference with plastome gene expression and Clp protease activity in Arabidopsis triggers a chloroplast unfolded protein response to restore protein homeostasis. cpUPR, LIN
70  2017 Liquid-phase sequence capture and targeted re-sequencing revealed novel polymorphisms in tomato genes belonging to the MEP carotenoid pathway. ---
71  2017 MEPicides: potent antimalarial prodrugs targeting isoprenoid biosynthesis. Dxr
72  2017 Metabolic engineering of Escherichia coli for production of valerenadiene. MVA
73  2017 Modeling of Dolichol Mass Spectra Isotopic Envelopes as a Tool to Monitor Isoprenoid Biosynthesis. Dols, MVA
74  2017 Molecular cloning and expression analysis of two key genes, HDS and HDR, in the MEP pathway in Pyropia haitanensis. HDR, HDS, MJ, ORF, SA
75  2017 Molecular cloning and functional identification of a cDNA encoding 4-hydroxy-3-methylbut-2-enyl diphosphate reductase from Tripterygium wilfordii. HDR, MJ, ORF
76  2017 Over-expression of DXS gene enhances terpenoidal secondary metabolite accumulation in rose-scented geranium and Withania somnifera: active involvement of plastid isoprenogenic pathway in their biosynthesis. ---
77  2017 Overexpression and Suppression of Artemisia annua 4-Hydroxy-3-Methylbut-2-enyl Diphosphate Reductase 1 Gene (AaHDR1) Differentially Regulate Artemisinin and Terpenoid Biosynthesis. AaHDR1, DMAPP, HDR, IPP
78  2017 Overexpression of endogenous 1-deoxy-d-xylulose 5-phosphate synthase (DXS) in cyanobacterium Synechocystis sp. PCC6803 accelerates protein aggregation. DXS, WT
79  2017 Overexpression of Populuscanescens isoprene synthase gene in Camelina sativa leads to alterations in its growth and metabolism. PcISPS
80  2017 Ozone Improves the Aromatic Fingerprint of White Grapes. LOX-HPL, VOCs
81  2017 Solanesol Biosynthesis in Plants. DXR, DXS, GGPPS, IPI, SDB
82  2017 The Methylerythritol Phosphate Pathway to Isoprenoids. ---
83  2017 [Research progress in multi-enzyme regulation of genetically engineered bacteria producing lycopene]. MVA
84  2016 A structural and functional study on the 2-C-methyl-d-erythritol-4-phosphate cytidyltransferase (IspD) from Bacillus subtilis. CDPME, CTP
85  2016 Aging and/or tissue-specific regulation of patchoulol and pogostone in two Pogostemon cablin (Blanco) Benth. cultivars. MVA
86  2016 Antimicrobial mechanism of theaflavins: They target 1-deoxy-D-xylulose 5-phosphate reductoisomerase, the key enzyme of the MEP terpenoid biosynthetic pathway. DXP, DXR
87  2016 Cloning and Expression Analysis of MEP Pathway Enzyme-encoding Genes in Osmanthus fragrans. ---
88  2016 Combinatorial engineering of hybrid mevalonate pathways in Escherichia coli for protoilludene production. DMAPP, FPP, IPP, MVA
89  2016 Combinatorial pathway optimization in Escherichia coli by directed co-evolution of rate-limiting enzymes and modular pathway engineering. ---
90  2016 Differential Contribution of the First Two Enzymes of the MEP Pathway to the Supply of Metabolic Precursors for Carotenoid and Chlorophyll Biosynthesis in Carrot (Daucus carota). DXS
91  2016 Differential Subplastidial Localization and Turnover of Enzymes Involved in Isoprenoid Biosynthesis in Chloroplasts. DXS
92  2016 Engineering of Recombinant Poplar Deoxy-D-Xylulose-5-Phosphate Synthase (PtDXS) by Site-Directed Mutagenesis Improves Its Activity. DMADP, DXS, IDP, PtDXS, ThDP
93  2016 Enhanced Diterpene Tanshinone Accumulation and Bioactivity of Transgenic Salvia miltiorrhiza Hairy Roots by Pathway Engineering. ---
94  2016 Environmental and Genetic Factors Associated with Solanesol Accumulation in Potato Leaves. MVA
95  2016 Expression of Terpenoid Biosynthetic Genes and Accumulation of Chemical Constituents in Valeriana fauriei. GC-MS, MVA, qRT-PCR, V. fauriei
96  2016 Farnesol-mediated shift in the metabolic origin of prenyl groups used for protein prenylation in plants. MVA
97  2016 Functional classification of rice flanking sequence tagged genes using MapMan terms and global understanding on metabolic and regulatory pathways affected by dxr mutant having defects in light response. DXR, FSTs, GO, IRFGC, non-TE
98  2016 Genome Sequence of the Red Pigment-Forming Meiothermus taiwanensis Strain RP Isolated from Paniphala Hot Spring, India. ---
99  2016 Isopentenyl diphosphate (IPP)-bypass mevalonate pathways for isopentenol production. IPP, MVA, PMD
100  2016 Molecular Mechanism of Action of Antimalarial Benzoisothiazolones: Species-Selective Inhibitors of the Plasmodium spp. MEP Pathway enzyme, IspD. ---