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■ Abbreviation / Long Form : MVA / mevalonic acid

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Total Number of Papers: 129
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Abbreviation:   MVA  (>> Co-occurring Abbreviation)
Long Form:   mevalonic acid
 Abbreviation Variation
 Long Form Variation
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No. Year Title Co-occurring Abbreviation
2019 Constructing Yeast Chimeric Pathways To Boost Lipophilic Terpene Synthesis. ---
2019 Engineering triterpene metabolism in the oilseed of Arabidopsis thaliana. DXS, FPS, MEP
2019 Terpenes and isoprenoids: a wealth of compounds for global use. DMAPP, IPP, MEP
2018 Anti-inflammatory fusicoccane-type diterpenoids from the phytopathogenic fungus Alternaria brassicicola. ---
2018 beta-Ecdysterone accumulation and regulation in Ajuga multiflora Bunge suspension culture. beta-EC, l-Phe, NO
2018 Synthesis of Heterologous Mevalonic Acid Pathway Enzymes in Clostridium ljungdahlii for the Conversion of Fructose and of Syngas to Mevalonate and Isoprene. IspS
2018 Tracing the biosynthetic origin of limonoids and their functional groups through stable isotope labeling and inhibition in neem tree (Azadirachta indica) cell suspension. DXS, HMGR, MEP, UPLC
2017 Combining Gal4p-mediated expression enhancement and directed evolution of isoprene synthase to improve isoprene production in Saccharomyces cerevisiae. IspS, MEP
2017 Comparative glandular trichome transcriptome-based gene characterization reveals reasons for differential (-)-menthol biosynthesis in Mentha species. GT, MD, MEP, TPSs
10  2017 Complex interplays between phytosterols and plastid development. FPS, IPP, MEP
11  2017 Inhibition of Prenylation Promotes Caspase 3 Activation, Lamin B Degradation and Loss in Metabolic Cell Viability in Pancreatic beta-Cells. ER
12  2017 [Research progress in multi-enzyme regulation of genetically engineered bacteria producing lycopene]. MEP
13  2016 Effect of mevalonic acid on cholesterol synthesis in bovine intramuscular and subcutaneous adipocytes. BIPs, BSPs, HDL-C, HMGR, LDL-C, PCR, TC
14  2016 Environmental and Genetic Factors Associated with Solanesol Accumulation in Potato Leaves. MEP
15  2016 Expression of Terpenoid Biosynthetic Genes and Accumulation of Chemical Constituents in Valeriana fauriei. GC-MS, MEP, qRT-PCR, V. fauriei
16  2016 Statins inhibit blastocyst formation by preventing geranylgeranylation. FPP, GGPP, HMG-CoA, YAP
17  2016 Sustainable heterologous production of terpene hydrocarbons in cyanobacteria. PHLS
18  2016 The potential of the mevalonate pathway for enhanced isoprenoid production. IPP, MEP
19  2016 The Transcript Profile of a Traditional Chinese Medicine, Atractylodes lancea, Revealing Its Sesquiterpenoid Biosynthesis of the Major Active Components. MEP, SSRs
20  2015 Allocate carbon for a reason: priorities are reflected in the C/C ratios of plant lipids synthesized via three independent biosynthetic pathways. ACT, DXP
21  2015 Breaking new ground in the regulation of the early steps of plant isoprenoid biosynthesis. MEP
22  2015 Characterization and function of the 3-hydroxy-3-methylglutaryl-CoA reductase gene in Alisma orientale (Sam.) Juz. and its relationship with protostane triterpene production. HMG-CoA, HMGR, ORF, Sam
23  2015 Effect of Enzyme Inhibitors on Terpene Trilactones Biosynthesis and Gene Expression Profiling in Ginkgo biloba Cultured Cells. MEP
24  2015 Insight into yeast: A study model of lipid metabolism and terpenoid biosynthesis. ---
25  2015 Jasmonate-induced biosynthesis of andrographolide in Andrographis paniculata. MeJA, MEP
26  2015 Orthologs of the archaeal isopentenyl phosphate kinase regulate terpenoid production in plants. DMAPP, IPK, IPP, MEP
27  2015 Skeletal muscle-specific HMG-CoA reductase knockout mice exhibit rhabdomyolysis: A model for statin-induced myopathy. HMGCR
28  2014 Biosynthesis of Taxadiene in Saccharomyces cerevisiae : selection of geranylgeranyl diphosphate synthase directed by a computer-aided docking strategy. FPP, GGPP, GGPPS, GGPPSbc, TCA
29  2014 Cloning and characterization of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR) gene from Paris fargesii Franch. HMGR, pI
30  2014 Enhanced isoprene biosynthesis in Saccharomyces cerevisiae by engineering of the native acetyl-CoA and mevalonic acid pathways with a push-pull-restrain strategy. ---
31  2014 Enhancing production of ergosterol in Pichia pastoris GS115 by over-expression of 3-hydroxy-3-methylglutaryl CoA reductase from Glycyrrhiza uralensis. GA, HMGR
32  2014 Heterologous expression of the mevalonic acid pathway in cyanobacteria enhances endogenous carbon partitioning to isoprene. DMAPP, IPP, MEP
33  2014 Influence of mevinolin on chloroplast terpenoids in Cannabis sativa. MEP, THC
34  2014 Measurement of HMG CoA reductase activity in different human cell lines by ultra-performance liquid chromatography tandem mass spectrometry. HMGCR, MVL
35  2014 Quantification of plant resistance to isoprenoid biosynthesis inhibitors. MEP
36  2014 Quantification of urinary mevalonic acid as a biomarker of HMG-CoA reductase activity by a novel translational LC-MS/MS method. ---
37  2014 S-carvone suppresses cellulase-induced capsidiol production in Nicotiana tabacum by interfering with protein isoprenylation. HMGR, MEP
38  2013 Biosynthesis of sesquiterpenes in grape berry exocarp of Vitis vinifera L.: evidence for a transport of farnesyl diphosphate precursors from plastids to the cytosol. HS-SPME-GC-MS
39  2013 Cloning and characterization of a cDNA coding 3-hydroxy-3-methylglutary CoA reductase involved in glycyrrhizic acid biosynthesis in Glycyrrhiza uralensis. HMGR
40  2013 Current development in isoprenoid precursor biosynthesis and regulation. DMAPP, IPP, MEP
41  2013 Methylerythritol phosphate pathway of isoprenoid biosynthesis. MEP
42  2013 Regulatory T cells contribute to rosuvastatin-induced cardioprotection against ischemia-reperfusion injury. cTnI, IR, IRI, RSV
43  2013 Statistical experimental design guided optimization of a one-pot biphasic multienzyme total synthesis of amorpha-4,11-diene. AD, DMAPP, FPP, IPP, IspA
44  2013 The SUD1 gene encodes a putative E3 ubiquitin ligase and is a positive regulator of 3-hydroxy-3-methylglutaryl coenzyme a reductase activity in Arabidopsis. dry2, ERAD-C, HMGR, SUD1
45  2012 3-Hydroxy-3-methylglutaryl coenzyme A reductase 1 (HMG1) is highly associated with the cell division during the early stage of fruit development which determines the final fruit size in Litchi chinensis. HMG1
46  2012 An ultrasensitive enzymatic method for measuring mevalonic acid in serum. HMGR, MVK
47  2012 De novo characterization of the root transcriptome of a traditional Chinese medicinal plant Polygonum cuspidatum. MEP
48  2012 Modular pathway engineering of diterpenoid synthases and the mevalonic acid pathway for miltiradiene production. MEP, MOPE
49  2012 No evidence for mevalonate shunting in moderately affected children with Smith-Lemli-Opitz syndrome. 7-DHC, SLOS, U-3MGC
50  2012 [Atorvastatin attenuates parathyroid hormone 1-34 induced cardiomyocytes hypertrophy through downregulating K-Ras-ERK1/2 pathway]. ANP, BNP, PTH 1-34
51  2011 Evidence of isoprenoid precursor toxicity in Bacillus subtilis. DMAPP, IPP, MEP
52  2011 Francisella tularensis 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase: kinetic characterization and phosphoregulation. MEP
53  2011 Liquid chromatography-tandem mass spectrometry method for the measurement of serum mevalonic acid: a novel marker of hydroxymethylglutaryl coenzyme A reductase inhibition by statins. HMG-CoA, MVAL
54  2011 Peroxisomal localisation of the final steps of the mevalonic acid pathway in planta. MVD, MVK, PMK, YFP
55  2011 The validation of a simple LC/MS/MS method for determining the level of mevalonic acid in human plasma. ---
56  2010 A genomics resource for investigating regulation of essential oil production in Lavandula angustifolia. DXP, DXS, ESTs, HMGR, LinS
57  2010 Pharmacokinetic/pharmacodynamic modeling and simulation of rosuvastatin using an extension of the indirect response model by incorporating a circadian rhythm. PK/PD
58  2010 The effects of rosuvastatin on the serum cortisol, serum lipid, and serum mevalonic acid levels in the healthy Indian male population. ---
59  2009 Effects of gibberellic acid on primary terpenoids and delta-tetrahydrocannabinol in Cannabis sativa at flowering stage. DXS, HMGR, MEP
60  2008 Molecular cloning and characterization of two cDNAs encoding 1-deoxy-D-xylulose 5-phosphate reductoisomerase from Hevea brasiliensis. MEP, ORF
61  2007 Are pleiotropic effects of statins real? HMG-CoA, LDL-C
62  2007 Up-regulation of an N-terminal truncated 3-hydroxy-3-methylglutaryl CoA reductase enhances production of essential oils and sterols in transgenic Lavandula latifolia. ---
63  2006 Cloning and characterization of a root-specific expressing gene encoding 3-hydroxy-3-methylglutaryl coenzyme A reductase from Ginkgo biloba. ---
64  2006 Effects of exogenous mevalonic acid on sterol lipid classes in Larix kaempferi callus. AS, FS
65  2006 Effects of various statins on cytokine-dependent growth and IgE-dependent release of histamine in human mast cells. HMG-CoA, IgE, IL, MCs, SCF
66  2006 Herbicidal effects of statin pharmaceuticals in Lemna gibba. HMGR, MEP
67  2006 Validation of the LC-MS/MS method for the quantification of mevalonic acid in human plasma and determination of the matrix effect. ---
68  2005 Metabolic engineering of the mevalonate and non-mevalonate isopentenyl diphosphate-forming pathways for the production of health-promoting isoprenoids in tomato. CaMV, dxs, IPP, MEP
69  2004 Are iridoids in leaf beetle larvae synthesized de novo or derived from plant precursors? A methodological approach. MEP
70  2004 Biosynthesis of the irregular monoterpene artemisia ketone, the sesquiterpene germacrene D and other isoprenoids in Tanacetum vulgare L. (Asteraceae). MEP
71  2004 Distinct light-mediated pathways regulate the biosynthesis and exchange of isoprenoid precursors during Arabidopsis seedling development. FSM, MEP, MEV
72  2004 The MEP pathway: a new target for the development of herbicides, antibiotics and antimalarial drugs. DMAPP, IPP, MEP
73  2003 Cross-talk between the cytosolic mevalonate and the plastidial methylerythritol phosphate pathways in tobacco bright yellow-2 cells. DX, HMGR, MEP, TBY-2
74  2003 Extracellular signal-regulated kinase inhibition by statins inhibits neutrophil activation by ANCA. ANCA, HMG-CoA, MAPK, MPO, NBT, PMN, PR3, TNF-alpha
75  2003 Lovastatin and phospholipase Cgamma regulate constitutive and protein kinase C dependent integrin mediated interactions of human T-cells with collagen. HVS, IFN, IL, mAb, PB, PK, PLC, PMA, VLA
76  2002 ATP depletion is an important factor in DHEA-induced growth inhibition and apoptosis in BV-2 cells. 2,4-DNP, DHEA, DN, IAA, RN
77  2002 Inhibitory effect of fluvastatin on lysophosphatidylcholine-induced nonselective cation current in Guinea pig ventricular myocytes. LPC
78  2002 Isoprenoid biosynthesis in higher plants and in Escherichia coli: on the branching in the methylerythritol phosphate pathway and the independent biosynthesis of isopentenyl diphosphate and dimethylallyl diphosphate. DMAPP, IPP, MEP
79  2002 Overexpression of Arabidopsis thaliana farnesyl diphosphate synthase (FPS1S) in transgenic Arabidopsis induces a cell death/senescence-like response and reduced cytokinin levels. 2iP, FPS
80  2002 Pharmacodynamic effects and pharmacokinetics of a new HMG-CoA reductase inhibitor, rosuvastatin, after morning or evening administration in healthy volunteers. HMG-CoA, LDL-C
81  2002 Validation and application of an assay for the determination of mevalonic acid in human plasma by liquid chromatography tandem mass spectrometry. HPLC-MS-MS, LLOQ
82  2001 Determinants of variable response to statin treatment in patients with refractory familial hypercholesterolemia. LDL
83  2001 Simvastatin inhibits noradrenaline-induced hypertrophy of cultured neonatal rat cardiomyocytes. NA, ROS
84  2001 The biosynthetic incorporation of the intact leucine skeleton into sterol by the trypanosomatid Leishmania mexicana. HMG-CoA
85  2000 Inhibition of cholesterol synthesis by atorvastatin in homozygous familial hypercholesterolaemia. HoFH, LDL
86  1999 Elucidation of carbon sources used for the biosynthesis of fatty acids and sterols in the trypanosomatid Leishmania mexicana. PL, TAG
87  1998 Apolipoprotein E genotype and cholesterogenesis in polygenic hypercholesterolemia. apo, LDL, PH
88  1998 Cholesterol synthesis is increased in mixed hyperlipidaemia. ---
89  1998 Direct vascular effects of HMG-CoA reductase inhibitors. HMG-CoA, SMC
90  1998 Dolichol-like lipids with stimulatory effect on DNA synthesis: substrates for protein dolichylation? HMG-CoA
91  1998 Effects of mevinolin on cell cycle progression and viability of tobacco BY-2 cells. ---
92  1998 Enzyme immunoassay of urinary mevalonic acid and its clinical application. HMG-CoA
93  1998 Use of cholesterol precursors to assess changes in cholesterol synthesis under non-steady-state conditions. apoB, HMG-CoA, L/C, LDL
94  1997 A sensitive and selective method for the determination of mevalonic acid in dog plasma by gas chromatography/negative ion chemical ionization-mass spectrometry. PFB
95  1997 Direct association between the hepatic secretion of very-low-density lipoprotein apolipoprotein B-100 and plasma mevalonic acid and lathosterol concentrations in man. apoB, ASR, GC-MS, VLDL
96  1997 Upregulation of cholesterol synthesis after acute reduction of low density lipoprotein by apheresis in normocholesterolaemic subjects: evidence for a threshold effect. L/C, LDL
97  1997 [Pharmacological control of biosynthesis pathway of mevalonate: effect on the proliferation of arterial smooth muscle cells]. PFTase, SMC
98  1996 Acute hyperinsulinaemia decreases cholesterol synthesis less in subjects with non-insulin-dependent diabetes mellitus than in non-diabetic subjects. NIDDM, TC, TG
99  1996 Mevalonic acid is limiting for N-linked glycosylation and translocation of the insulin-like growth factor-1 receptor to the cell surface. Evidence for a new link between 3-hydroxy-3-methylglutaryl-coenzyme a reductase and cell growth. HMG-CoA, IGF-1, IGF-1R
100  1996 Plasma mevalonic acid, an index of cholesterol synthesis in vivo, and responsiveness to HMG-CoA reductase inhibitors in familial hypercholesterolaemia. FH, LDL