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■ Abbreviation / Long Form : NHERF / Na(+)/H(+) exchanger regulatory factor

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Total Number of Papers: 51
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Abbreviation:   NHERF  (>> Co-occurring Abbreviation)
Long Form:   Na(+)/H(+) exchanger regulatory factor
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No. Year Title Co-occurring Abbreviation
2019 Loss of the Na+/H+ Exchange Regulatory Factor 1 Increases Susceptibility to Cisplatin-Induced Acute Kidney Injury. AKI
2019 NHERF3 is necessary for Escherichia coli heat-stable enterotoxin-induced inhibition of NHE3: differences in signaling in mouse small intestine and Caco-2 cells. ETEC, ST
2017 Dynamic NHERF interaction with TRPC4/5 proteins is required for channel gating by diacylglycerol. DAG, PLC
2017 FGF23-Klotho signaling axis in the kidney. FGF23, SGK1
2017 Na+/H+ exchange regulatory factor 1 is required for ROMK1 K+ channel expression in the surface membrane of cultured M-1 cortical collecting duct cells. CCD
2017 PDZ domain-dependent regulation of NHE3 protein by both internal Class II and C-terminal Class I PDZ-binding motifs. PBMs, PM
2016 Deletion of Na+/H+ exchanger regulatory factor 2 represses colon cancer progress by suppression of Stat3 and CD24. CRC, LPA2
2016 NHERF1 regulates actin cytoskeleton organization through modulation of alpha-actinin-4 stability. F-actin
2015 Drug Transporters and Na+/H+ Exchange Regulatory Factor PSD-95/Drosophila Discs Large/ZO-1 Proteins. PDZ
10  2015 The NHERF2 sequence adjacent and upstream of the ERM-binding domain affects NHERF2-ezrin binding and dexamethasone stimulated NHE3 activity. EBRS, ERM, OK
11  2014 Lysophosphatidic acid stimulation of NHE3 exocytosis in polarized epithelial cells occurs with release from NHERF2 via ERK-PLC-PKCdelta signaling. BB, EGFR, LPA, MV, NHE3, OK, ROCK
12  2013 Differential association of the Na+/H+ Exchanger Regulatory Factor (NHERF) family of adaptor proteins with the raft- and the non-raft brush border membrane fractions of NHE3. BBM
13  2013 Ezrin, a membrane cytoskeletal cross-linker, is essential for the regulation of phosphate and calcium homeostasis. ---
14  2013 NHERF2 protein mobility rate is determined by a unique C-terminal domain that is also necessary for its regulation of NHE3 protein in OK cells. ERM, PDZ
15  2012 FGF23 acts directly on renal proximal tubules to induce phosphaturia through activation of the ERK1/2-SGK1 signaling pathway. FGF23
16  2011 NHERF1 and NHERF2 are necessary for multiple but usually separate aspects of basal and acute regulation of NHE3 activity. BB, cGK, HA, KD, NHE3, shRNA, siRNA
17  2011 Regulation of G protein-coupled receptor function by Na+/H+ exchange regulatory factors. GPCR, PTB, SH3
18  2009 GABARAP deficiency modulates expression of NaPi-IIa in renal brush-border membranes. BBM, GABARAP, TRL
19  2008 The epithelial brush border Na+/H+ exchanger NHE3 associates with the actin cytoskeleton by binding to ezrin directly and via PDZ domain-containing Na+/H+ exchanger regulatory factor (NHERF) proteins. BB
20  2007 Canonical transient receptor potential 5. PI
21  2007 NHERF links the N-cadherin/catenin complex to the platelet-derived growth factor receptor to modulate the actin cytoskeleton and regulate cell motility. PDGFRbeta, PDZ
22  2007 NHERF1/EBP50 head-to-tail intramolecular interaction masks association with PDZ domain ligands. EBP50, ERM
23  2006 Structural basis for NHERF recognition by ERM proteins. ---
24  2005 Beyond the brush border: NHERF4 blazes new NHERF turf. ---
25  2005 Expression of TRPC4 channel protein that interacts with NHERF-2 in rat descending vasa recta. DVR, TRPC
26  2005 Ezrin controls the macromolecular complexes formed between an adapter protein Na+/H+ exchanger regulatory factor and the cystic fibrosis transmembrane conductance regulator. CFTR
27  2005 Gp135/podocalyxin and NHERF-2 participate in the formation of a preapical domain during polarization of MDCK cells. PDZ
28  2004 Control of epithelial ion transport by Cl- and PDZ proteins. CFTR, ENaC
29  2004 Phosphorylation of the platelet-derived growth factor receptor-beta by G protein-coupled receptor kinase-2 reduces receptor signaling and interaction with the Na(+)/H(+) exchanger regulatory factor. EGFR, GRK2, PDGFRbeta
30  2004 The Na+/H+ exchanger regulatory factor stabilizes epidermal growth factor receptors at the cell surface. EGFRs, RTKs
31  2003 A kinase-regulated mechanism controls CFTR channel gating by disrupting bivalent PDZ domain interactions. CFTR, PDZ, Po
32  2003 Crystallographic characterization of the radixin FERM domain bound to the C-terminal region of the human Na+/H+-exchanger regulatory factor (NHERF). NHERFs
33  2003 Localization and interaction of NHERF isoforms in the renal proximal tubule of the mouse. ---
34  2003 Stimulation of beta 2-adrenergic receptor increases cystic fibrosis transmembrane conductance regulator expression in human airway epithelial cells through a cAMP/protein kinase A-independent pathway. CFTR, HAEC, PDZ
35  2003 The role of the C terminus and Na+/H+ exchanger regulatory factor in the functional expression of cystic fibrosis transmembrane conductance regulator in nonpolarized cells and epithelia. CFTR, PDZ
36  2002 Na(+)/H(+ ) exchanger regulatory factor 2 directs parathyroid hormone 1 receptor signalling. PTH1R, PTHrP
37  2002 Structural determinants of the Na+/H+ exchanger regulatory factor interaction with the beta 2 adrenergic and platelet-derived growth factor receptors. ---
38  2002 Targeted disruption of the mouse NHERF-1 gene promotes internalization of proximal tubule sodium-phosphate cotransporter type IIa and renal phosphate wasting. PDZ
39  2001 Crystal structure of the PDZ1 domain of human Na(+)/H(+) exchanger regulatory factor provides insights into the mechanism of carboxyl-terminal leucine recognition by class I PDZ domains. CFTR, PDGFR
40  2001 Crystallographic characterization of the PDZ1 domain of the human Na+/H+ exchanger regulatory factor. ---
41  2001 Differential renal distribution of NHERF isoforms and their colocalization with NHE3, ezrin, and ROMK. NHE3
42  2001 Essential role for NHERF in cAMP-mediated inhibition of the Na+-HCO3- co-transporter in BSC-1 cells. PKA
43  2001 Ezrin binding domain-deficient NHERF attenuates cAMP-mediated inhibition of Na(+)/H(+) exchange in OK cells. 8-BrcAMP, NHE3, OK
44  2001 NHERF: targeting and trafficking membrane proteins. NHE3
45  2001 Phosphorylation and cell cycle-dependent regulation of Na+/H+ exchanger regulatory factor-1 by Cdc2 kinase. ---
46  2001 Regulation of cystic fibrosis transmembrane conductance regulator single-channel gating by bivalent PDZ-domain-mediated interaction. CFTR
47  2001 Structural basis of the Na+/H+ exchanger regulatory factor PDZ1 interaction with the carboxyl-terminal region of the cystic fibrosis transmembrane conductance regulator. CFTR
48  2000 Platelet-derived growth factor receptor association with Na(+)/H(+) exchanger regulatory factor potentiates receptor activity. ERK, PDGF, PDGFR, PDGFR-CT
49  1999 G protein-coupled receptor kinase 6A phosphorylates the Na(+)/H(+) exchanger regulatory factor via a PDZ domain-mediated interaction. HEK293
50  1998 A C-terminal motif found in the beta2-adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na+/H+ exchanger regulatory factor family of PDZ proteins. ---
51  1998 The beta2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange. NHE, NHE3