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■ Abbreviation / Long Form : NUPR1 / nuclear protein 1

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Total Number of Papers: 47
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Abbreviation:   NUPR1  (>> Co-occurring Abbreviation)
Long Form:   nuclear protein 1
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No. Year Title Co-occurring Abbreviation
2020 Combination of AAV‑mediated NUPR1 knockdown and trifluoperazine induces premature senescence in human lung adenocarcinoma A549cells in nude mice. AAV, TFP
2020 Downregulation of nuclear protein-1 induces cell cycle arrest in G0/G1 phase in glioma cells in vivo and in vitro via P27. ---
2020 Epigenetic silencing of microRNA-874-3p implicates in erectile dysfunction in diabetic rats by activating the Nupr1/Chop-mediated pathway. CSMCs, DMED, miR-874-3p, TBARS
2020 Nuclear protein 1 imparts oncogenic potential and chemotherapeutic resistance in cancer. COM1
2020 NUPR1 Silencing Induces Autophagy-Mediated Apoptosis in Multiple Myeloma Cells Through the PI3K/AKT/mTOR Pathway. DS, MM, R-ISS
2020 Single-Cell Transcriptomics Analysis Identifies Nuclear Protein 1 as a Regulator of Docetaxel Resistance in Prostate Cancer Cells. scRNA-seq
2020 Tetrandrine partially reverses multidrug resistance of human laryngeal cancer cells. HTRA1, MDR, MDR1, RGS10, VCR
2020 Trifluoperazine induces cellular apoptosis by inhibiting autophagy and targeting NUPR1 in multiple myeloma. MM, TFP
2020 ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents. DDR
10  2019 Deficiency of stress-associated gene Nupr1 increases bone volume by attenuating differentiation of osteoclasts and enhancing differentiation of osteoblasts. SOST
11  2019 Gene Expression Analysis of the Activating Factor 3/Nuclear Protein 1 Axis in a Non-alcoholic Steatohepatitis Mouse Model. ATF3, CHOP, ER, FLS, NAFLD/NASH, TUNEL
12  2019 Induction of nuclear protein-1 by thyroid hormone enhances platelet-derived growth factor A mediated angiogenesis in liver cancer. HCC, HUVECs, PDGF-A
13  2019 Nupr1 regulates palmitate-induced apoptosis in human articular chondrocytes. ATF4, CC3, CHOP, FFA, OA, TRB3
14  2019 Targeting the Stress-Induced Protein NUPR1 to Treat Pancreatic Adenocarcinoma. IDP, NLS
15  2019 Targeting XPO1 and PAK4 in 8505C Anaplastic Thyroid Cancer Cells: Putative Implications for Overcoming Lenvatinib Therapy Resistance. PFS, TKI
16  2018 Amphipathic helical peptides hamper protein-protein interactions of the intrinsically disordered chromatin nuclear protein 1 (NUPR1). C-RING1B, CD, IDP, ITC, MD, NMR, PDAC, PLAs, TFP
17  2018 Knockdown of NUPR1 inhibits the growth of U266 and RPMI8226 multiple myeloma cell lines via activating PTEN and caspase activation‑dependent apoptosis. MM, PTEN
18  2018 Serum from Chronic Hepatitis B Patients Promotes Growth and Proliferation via the IGF-II/IGF-IR/MEK/ERK Signaling Pathway in Hepatocellular Carcinoma Cells. HBV, HCC, HDs, HRP-2, IGF, IGF-IR, siRNA
19  2017 Glucose Restriction Combined with Autophagy Inhibition and Chemotherapy in HCT 116 Spheroids Decreases Cell Clonogenicity and Viability Regulated by Tumor Suppressor Genes. Per2
20  2017 Inhibition of the Cell Death Pathway in Nonalcoholic Steatohepatitis (NASH)-Related Hepatocarcinogenesis Is Associated with Histone H4 lysine 16 Deacetylation. HCC, NASH
21  2017 Knockdown of NUPR1 inhibits the proliferation of glioblastoma cells via ERK1/2, p38 MAPK and caspase-3. IHC
22  2017 [Knockdown of nuclear protein 1 (NUPR1) gene inhibits proliferation and promotes apoptosis of human multiple myeloma U266 cells]. NUPR1-shRNA, qRT-PCR
23  2016 A liver stress-endocrine nexus promotes metabolic integrity during dietary protein dilution. DPD, FGF21, NEAAs, T2D, UCP1
24  2016 Downregulation of YAP-dependent Nupr1 promotes tumor-repopulating cell growth in soft matrices. TRCs
25  2016 NUPR1, a new target in liver cancer: implication in controlling cell growth, migration, invasion and sorafenib resistance. HCC
26  2015 Functional Characterization of Nupr1L, A Novel p53-Regulated Isoform of the High-Mobility Group (HMG)-Related Protumoral Protein Nupr1. HMG, NUPR1L
27  2015 Hepatitis B virus X promotes hepatocellular carcinoma development via nuclear protein 1 pathway. HBV, HBx, HCC
28  2015 Identification of a mitochondrial defect gene signature reveals NUPR1 as a key regulator of liver cancer progression. ---
29  2015 Integrated analysis of microRNAs, transcription factors and target genes expression discloses a specific molecular architecture of hyperdiploid multiple myeloma. miRNA, MM, STAT, TGF-beta
30  2015 Mitochondrial defect-responsive gene signature in liver-cancer progression. CMD, GRN, HCC
31  2015 Nidogen 1 and Nuclear Protein 1: novel targets of ETV5 transcription factor involved in endometrial cancer invasion. NID1
32  2015 Reduced nuclear protein 1 expression improves insulin sensitivity and protects against diet-induced glucose intolerance through up-regulation of heat shock protein 70. HSP70
33  2015 [Nuclear protein 1 knockdown inhibits proliferation and migration of HepG2 cells]. shRNAs
34  2014 Brief report: stress-inducible nuclear protein 1 regulates matrix metalloproteinase 13 expression in human articular chondrocytes. DMM, IL-1beta, MMP-13, mRNA, OA, TBHP
35  2014 Genetic inactivation of Nupr1 acts as a dominant suppressor event in a two-hit model of pancreatic carcinogenesis. PanINs, PDAC, QM
36  2014 Genetic inactivation of the pancreatitis-inducible gene Nupr1 impairs PanIN formation by modulating Kras(G12D)-induced senescence. PanIN
37  2012 Cytoplasmic translocation of p21 mediates NUPR1-induced chemoresistance: NUPR1 and p21 in chemoresistance. ---
38  2012 Expression and roles of NUPR1 in cholangiocarcinoma cells. ---
39  2012 Homotypic cell cannibalism, a cell-death process regulated by the nuclear protein 1, opposes to metastasis in pancreatic cancer. HoCC, PDAC
40  2012 Lentivirus-mediated RNAi knockdown of NUPR1 inhibits human nonsmall cell lung cancer growth in vitro and in vivo. NSCLC, siRNA
41  2012 Nuclear protein 1 promotes pancreatic cancer development and protects cells from stress by inhibiting apoptosis. IER3, PanINs, PDAC
42  2012 The human NUPR1/P8 gene is transcriptionally activated by transforming growth factor beta via the SMAD signalling pathway. 5'-UTR, COM1
43  2010 Stress-inducible protein p8 is involved in several physiological and pathological processes. ---
44  2009 Emerging role of nuclear protein 1 (NUPR1) in cancer biology. ---
45  2009 Nuclear protein 1 induced by ATF4 in response to various stressors acts as a positive regulator on the transcriptional activation of ATF4. ATF4
46  2007 EPO modulation of cell-cycle regulatory genes, and cell division, in primary bone marrow erythroblasts. Bcl-6, Egr-1, GSPT1, NAB2
47  2007 Gene expression in the liver of rainbow trout, Oncorhynchus mykiss, during the stress response. G6Pase, MHC1