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■ Abbreviation / Long Form : OFQ/N / orphanin FQ/nociceptin

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Total Number of Papers: 84
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Abbreviation:   OFQ/N  (>> Co-occurring Abbreviation)
Long Form:   orphanin FQ/nociceptin
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No. Year Title Co-occurring Abbreviation
2016 Estradiol Rapidly Attenuates ORL-1 Receptor-Mediated Inhibition of Proopiomelanocortin Neurons via Gq-Coupled, Membrane-Initiated Signaling. Akt, ER, GIRK, Gq-mER, MPN, nNOS, ORL, PI3K, PKA, PKC, PLC, POMC
2016 Modulatory influences of estradiol and other anorexigenic hormones on metabotropic, Gi/o-coupled receptor function in the hypothalamic control of energy homeostasis. ORL, PI3K, POMC
2014 Gonadal steroids differentially modulate the actions of orphanin FQ/nociceptin at a physiologically relevant circuit controlling female sexual receptivity. GIRK, mEPSCs, mIPSCs, POMC
2014 Interactions of orphanin FQ/nociceptin (OFQ/N) system with immune system factors and hypothalamic-pituitary-adrenal (HPA) axis. HPA
2013 Estradiol negatively modulates the pleiotropic actions of orphanin FQ/nociceptin at proopiomelanocortin synapses. mEPSCs, MPN, ORL, POMC
2012 Biphasic regulation of the acute mu-withdrawal and CCk-8 contracture responses by the ORL-1 system in guinea pig ileum. CCK-8, GPI
2011 Orphanin FQ/nociceptin activates nuclear factor kappa B. GPCR, NF-kappaB, NOPr
2010 Orphanin FQ/nociceptin not only blocks but also reverses behavioral adaptive changes induced by repeated cocaine in mice. ---
2010 Role of opioid receptor like-1 receptor in modulation of endocrine, immunological, and behavioral responses to the T-cell superantigen staphylococcal enterotoxin A. SEA
10  2010 The role of the NOP receptor in regulating food intake, meal pattern, and the excitability of proopiomelanocortin neurons. ARC, GIRK, NOP, POMC
11  2008 Alterations in the level of OFQ/N-IR in rat brain regions by cocaine. ---
12  2008 The anxiolytic-like effects of the novel, orally active nociceptin opioid receptor agonist 8-[bis(2-methylphenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol (SCH 221510). CDP, NOP
13  2008 The endogenous OFQ/N/ORL-1 receptor system regulates the rewarding effects of acute cocaine. CPP
14  2008 The orphanin FQ/nociceptin (OFQ/N) system. GPCR
15  2008 The role of the opioid receptor-like (ORL1) receptor in motor stimulatory and rewarding actions of buprenorphine and morphine. ---
16  2007 Effect of orphanin FQ/nociceptin (OFQ/N) and isoflurane on the prolactin secretory response in OFQ/N knockout mice. ---
17  2007 Orphanin FQ/nociceptin interacts with the basolateral amygdala noradrenergic system in memory consolidation. BLA
18  2007 Release of orphanin FQ/nociceptin in the medial preoptic nucleus and ventromedial nucleus of the hypothalamus facilitates lordosis. MPN, VMH
19  2006 Endogenous orphanin FQ/nociceptin is involved in the development of morphine tolerance. ---
20  2006 Immunolocalization of orphanin FQ in rat cochlea. ---
21  2006 Orphanin FQ/nociceptin interactions with the immune system in vivo: gene expression changes in lymphoid organs and regulation of the cytokine response to staphylococcal enterotoxin A. SEA
22  2006 Orphanin FQ/nociceptin is a physiological regulator of prolactin secretion in female rats. comp-B, ORL-1, TIDA
23  2006 The Orphanin FQ / Nociceptin receptor as a novel drug target in psychiatric disorders. ---
24  2005 Lack of involvement of dopamine and serotonin during the orphanin FQ/Nociceptin (OFQ/N)-induced prolactin secretory response. ---
25  2005 Orphanin FQ/nociceptin potentiates [D-Ala2,N-Me-Phe4,Gly5-ol]-enkephalin-Induced mu-opioid receptor phosphorylation. GRK, NOP
26  2004 Orphanin FQ/nociceptin suppresses motor activity through an action along the mesoaccumbens axis in rats. VTA
27  2003 Acetyl-RYYRIK-NH2, a purported orphanin FQ antagonist, does not block the orphanin FQ-induced prolactin secretory response in female rats. ---
28  2003 Mu-opioid-induced desensitization of opioid receptor-like 1 and mu-opioid receptors: differential intracellular signaling determines receptor sensitivity. GRKs, ORL1
29  2003 Orphanin FQ/nociceptin: from neural circuitry to behavior. ---
30  2002 A combined pharmacological and genetic approach to investigate the role of orphanin FQ in learning and memory. KO, ORL1
31  2002 Characterization of rat prepro-orphanin FQ/nociceptin((154-181)): nociceptive processing in supraspinal sites. LC, RVM, vlPAG
32  2002 Dimerization of morphine and orphanin FQ/nociceptin receptors: generation of a novel opioid receptor subtype. ---
33  2002 Expression of orphanin FQ/nociceptin and its receptor in rat peripheral ganglia and spinal cord. ---
34  2002 Immunological challenge modulates brain orphanin FQ/nociceptin and nociceptive behavior. LPS, SEA
35  2002 Induction of G protein-coupled receptor kinases 2 and 3 contributes to the cross-talk between mu and ORL1 receptors following prolonged agonist exposure. GRKs, ORL1, PKC
36  2002 Involvement of the neuropeptide orphanin FQ/nociceptin in kainate and kindling seizures and epileptogenesis. mRNA
37  2002 Novel orphanin FQ/nociceptin transcripts are expressed in human immune cells. PBLs
38  2002 Orphanin FQ/nociceptin blocks chronic morphine-induced tyrosine hydroxylase upregulation. ERKs, LC, ORL1, VTA
39  2002 Orphanin FQ/nociceptin blocks cocaine-induced behavioral sensitization in rats. aCSF
40  2002 Orphanin FQ/nociceptin but not Ro 65-6570 inhibits the expression of cocaine-induced conditioned place preference. CPP, DA, i.c.v, ORL-1
41  2002 Orphanin FQ/nociceptin-mediated desensitization of opioid receptor-like 1 receptor and mu opioid receptors involves protein kinase C: a molecular mechanism for heterologous cross-talk. GRK2, ORL1
42  2002 Rat ventral midbrain dopamine neurons express the orphanin FQ/nociceptin receptor ORL-1. ---
43  2002 Sensitization to cocaine after a single intra-cerebral injection of orphanin FQ/nociceptin. ---
44  2001 Analgesia elicited by OFQ/nociceptin and its fragments from the amygdala in rats. ---
45  2001 Carboxyl terminal peptides derived from prepro-orphanin FQ/nociceptin (ppOFQ/N) are produced in the hypothalamus and possess analgesic bioactivities. ---
46  2001 Differential antagonism by naloxone benzoylhydrazone of the activation of inward rectifying K+ channels by nociceptin and a mu-opioid in rat periaqueductal grey slices. NalBzoH, PAG
47  2001 Differential splicing of transcripts encoding the orphanin FQ/nociceptin precursor. ---
48  2001 Dynorphin A inhibits nociceptin-converting enzyme from the rat spinal cord. NCE
49  2001 Orphanin FQ/nociceptin and naloxone benzoylhydrazone activate distinct receptors in BE(2)-C human neuroblastoma cells. NalBzoH
50  2001 Orphanin FQ/nociceptin attenuates the development of morphine tolerance in rats. aCSF
51  2001 Orphanin FQ/nociceptin binds to functionally coupled ORL1 receptors on human immune cell lines and alters peripheral blood mononuclear cell proliferation. ---
52  2001 Pharmacological characterization of the novel nonpeptide orphanin FQ/nociceptin receptor agonist Ro 64-6198: rapid and reversible desensitization of the ORL1 receptor in vitro and lack of tolerance in vivo. ---
53  2001 The molecular and behavioral pharmacology of the orphanin FQ/nociceptin peptide and receptor family. ---
54  2000 A cellular mechanism for the bidirectional pain-modulating actions of orphanin FQ/nociceptin. ---
55  2000 Effects of supraspinal orphanin FQ/nociceptin. ---
56  2000 Integrity of tritiated orphanin FQ/nociceptin: implications for establishing a reliable binding assay. HPLC
57  2000 Neurohumoral effects of orphanin FQ/nociceptin: relevance to cardiovascular and renal function. ---
58  2000 Orphanin FQ/nociceptin and [Phe(1)Psi(CH(2)-NH)Gly(2)] nociceptin(1-13)-NH(2) stimulate gastric motor function in anaesthetized rats. ---
59  2000 Orphanin FQ/nociceptin inhibits morphine withdrawal. i.p
60  2000 Orphanin FQ/nociceptin: a novel neuromodulator of gastrointestinal function? ---
61  2000 Pharmacological characterization of the nociceptin receptor, ORL1. Insight from the inward rectifier activation in the periaqueductal gray. NBZ
62  2000 The orphanin FQ/nociceptin gene: structure, tissue distribution of expression and functional implications obtained from knockout mice. ---
63  1999 Activation of an inwardly rectifying K+ conductance by orphanin-FQ/nociceptin in vasopressin-containing neurons. CARB, SON
64  1999 Cardiovascular and renal responses produced by central orphanin FQ/nociceptin occur independent of renal nerves. RSNA
65  1999 Central administration of [Phe1psi(CH2-NH)Gly2]nociceptin(1-13)-NH2 and orphanin FQ/nociceptin (OFQ/N) produce similar cardiovascular and renal responses in conscious rats. ---
66  1999 Identification of a high-affinity orphanin FQ/nociceptin(1-11) binding site in mouse brain. ---
67  1999 Injection of orphanin FQ/nociceptin into the periaqueductal gray suppresses the forebrain-elicited vocalization in the guinea pig. AC, FEV, PAG
68  1999 Metabolic fate of nociceptin/orphanin FQ in the rat spinal cord and biological activity of its released fragment. ---
69  1999 Orphanin FQ/nociceptin blocks acquisition of morphine place preference. ---
70  1999 Orphanin-FQ/nociceptin (OFQ/N) modulates the activity of suprachiasmatic nucleus neurons. NOR, SCN
71  1999 Peripheral orphanin FQ/nociceptin analgesia in the mouse. ---
72  1999 Strain-dependent effects of supraspinal orphanin FQ/nociceptin on thermal nociceptive sensitivity in mice. i.c.v, SIA
73  1999 [(125)I]orphanin FQ/nociceptin binding in Raji cells. ---
74  1999 [Phe1psi(CH2-NH)Gly2]nociceptin-(1 - 13)-NH2 activation of an inward rectifier as a partial agonist of ORL1 receptors in rat periaqueductal gray. ---
75  1998 Analgesic activity of orphanin FQ2, murine prepro-orphanin FQ141-157 in mice. OFQ2, ppOFQ
76  1998 Antinociceptive analogs of orphanin FQ/nociceptin(1-11). ---
77  1998 Functional blockade of opioid analgesia by orphanin FQ/nociceptin. ---
78  1998 Orphanin FQ/nociceptin analgesia in the rat. ---
79  1998 [Phe1psi(CH2-NH)Gly2]nociceptin-(1-13)-NH2 acts as an agonist of the orphanin FQ/nociceptin receptor in vivo. ---
80  1997 Biochemical evidence for orphanin FQ/nociceptin receptor heterogeneity in mouse brain. ---
81  1997 Orphanin FQ/nociceptin in the ventromedial nucleus facilitates lordosis in female rats. VMH
82  1997 Pharmacological characterization of orphanin FQ/nociceptin and its fragments. ---
83  1997 Spinal analgesic activity of orphanin FQ/nociceptin and its fragments. ---
84  1996 Dissociation of affinity and efficacy in KOR-3 chimeras. ---