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■ Abbreviation / Long Form : P-gp / permeability glycoprotein

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Total Number of Papers: 120
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Abbreviation:   P-gp  (>> Co-occurring Abbreviation)
Long Form:   permeability glycoprotein
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No. Year Title Co-occurring Abbreviation
2020 Activity and mechanism of flavokawain A in inhibiting P-glycoprotein expression in paclitaxel resistance of lung cancer. FKA, PTX
2020 Long Noncoding RNA Plasmacytoma Variant Translocation 1 Regulates Cisplatin Resistance via miR-3619-5p/TBL1XR1 Axis in Gastric Cancer. GC, GST-pi, lncRNA, miR, PVT1, TBL1XR1
2020 Raised CD40L expression attenuates drug resistance in Adriamycin-resistant THP-1 cells. ADM, CD40L, DNR, MDR, MRP1
2019 18 F-Labeled benzylpiperazine derivatives as highly selective ligands for imaging sigma1 receptor with positron emission tomography. EOS, RCP
2019 CD73 Promotes Glioblastoma Pathogenesis and Enhances Its Chemoresistance via A2B Adenosine Receptor Signaling. AR, GB, MRP1
2019 Effects of simvastatin on the PXR signaling pathway and the liver histology in Mugilogobius abei. CAT, CYP3A, ERND, GST, MDA, PXR, SOD
2019 Image-based QSAR Model for the Prediction of P-gp Inhibitory Activity of Epigallocatechin and Gallocatechin Derivatives. ANN, CCC, PCR, PCs, QSAR, RMSE, SVM
2019 Nucleic acid sensing activates the innate cytosolic surveillance pathway and promotes parasite survival in visceral leishmaniasis. cGAS, CSP, Ld-DNA, PAMP, SBR-LD, TREX-1
2019 Pharmacokinetic and Drug-Drug Interaction Profiles of the Combination of Tezacaftor/Ivacaftor. AUC, DDI, PKs
10  2019 Prolactin Elevations and Permeability Glycoprotein. ---
11  2019 Protein Abundance of Clinically Relevant Drug Transporters in the Human Liver and Intestine: A Comparative Analysis in Paired Tissue Specimens. ABC, BCRP, MCT, MRP, OATP, OCT
12  2019 Reduced pim-1 expression increases chemotherapeutic drug sensitivity in human androgen-independent prostate cancer cells by inducing apoptosis. shRNA
13  2019 Tablet formulation of Famotidine-loaded P-gp inhibiting nanoparticles using PLA-g-PEG grafted polymer. NPs, PLA
14  2019 The Effect of Compound Sophora on Fluorouracil and Oxaliplatin Resistance in Colorectal Cancer Cells. ABCG2, ANXA1
15  2019 The pharmacokinetic properties of HIV-1 protease inhibitors: A computational perspective on herbal phytochemicals. COA-FS, HIV, PIs
16  2019 Up-regulation of P-gp via NF-kappaB activation confers protection against oxidative damage in the retinal pigment epithelium cells. MDR1, NF-kappaB, RPE, siRNA
17  2019 Verapamil as a culprit of palbociclib toxicity. ---
18  2018 10-Phenyltriazoyl Artemisinin is a Novel P-glycoprotein Inhibitor that Suppresses the Overexpression and Function of P-glycoprotein. ---
19  2018 Drug-Drug Interaction Study of Apixaban with Cyclosporine and Tacrolimus in Healthy Volunteers. BCRP, CIs, Cmax, GMRs
20  2018 Post-mortem analysis of suicide victims shows ABCB1 haplotype 1236T-2677T-3435T as a candidate predisposing factor behind adverse drug reactions in females. ---
21  2018 Using LC-MS/MS-based targeted proteomics to monitor the pattern of ABC transporters expression in the development of drug resistance. ABC transporters, ADM, BCRP, MDR, MS, MTX, MX
22  2017 Clinical pharmacokinetics of an amorphous solid dispersion tablet of elacridar. ASD, BCRP
23  2017 Effects on P-Glycoprotein Expression after Blood-Brain Barrier Disruption Using Focused Ultrasound and Microbubbles. BBB-D, FUS
24  2017 Investigating Structural Requirements for the Antiproliferative Activity of Biphenyl Nicotinamides. ---
25  2017 Knockdown of PKM2 and GLS1 expression can significantly reverse oxaliplatin-resistance in colorectal cancer cells. CRC, PCR, PKM2
26  2017 Recurrent venous thrombosis under rivaroxaban and carbamazepine for symptomatic epilepsy. CYP3A4, DOAC, VKAs
27  2017 Relationship Between ABCB1 Polymorphisms and Cold Pain Sensitivity Among Healthy Opioid-naive Malay Males. CPT
28  2017 Therapeutic Potential and Utility of Elacridar with Respect to P-glycoprotein Inhibition: An Insight from the Published In Vitro, Preclinical and Clinical Studies. ---
29  2017 Zebrafish as a Screening Model for Testing the Permeability of Blood-Brain Barrier to Small Molecules. LPM
30  2016 (18)F-FCWAY, a serotonin 1A receptor radioligand, is a substrate for efflux transport at the human blood-brain barrier. BCRP, FACS, PET
31  2016 A common polymorphism in the ABCB1 gene is associated with side effects of PGP-dependent antidepressants in a large naturalistic Dutch cohort. SNP
32  2016 Does the Clearance of Inhaled (99m)Tc-Sestamibi Correlate with Multidrug Resistance Protein 1 Expression in the Human Lung? MRP1
33  2016 Drug Interactions of Direct-Acting Oral Anticoagulants. DOACs
34  2016 Identification of a key role for permeability glycoprotein in enhancing the cellular defense mechanisms of fertilized oocytes. DSBs
35  2016 Image-Based Analysis to Predict the Activity of Tariquidar Analogs as P-Glycoprotein Inhibitors: The Importance of External Validation. CCC, PCs, QSAR
36  2016 Influence of P-Glycoprotein Function on Chronic Rhinosinusitis/Nasal Polyps Pathophysiology. CRS
37  2016 Knockdown of MACC1 expression increases cisplatin sensitivity in cisplatin-resistant epithelial ovarian cancer cells. Bcl-2, MACC1
38  2016 Predictive value of microparticle-associated tissue factor activity for permeability glycoprotein-mediated multidrug resistance in cancer. FVII, MDR, MPs, TF
39  2016 Relationship between ABCB1 polymorphisms and serum methadone concentration in patients undergoing methadone maintenance therapy (MMT). DNA, MMT, PCR
40  2016 Reversal of Chemoresistance in Ovarian Cancer by Co-Delivery of a P-Glycoprotein Inhibitor and Paclitaxel in a Liposomal Platform. LP, PCT
41  2016 Synergistic anticancer effect of exogenous wild-type p53 gene combined with 5-FU in human colon cancer resistant to 5-FU in vivo. 5-FU, 5-FU, MRP1, PKC, rAd-p53
42  2016 Using the Variable-Nearest Neighbor Method To Identify P-Glycoprotein Substrates and Inhibitors. QSAR, v-NN
43  2015 A comparative PET imaging study with the reversible and irreversible EGFR tyrosine kinase inhibitors [(11)C]erlotinib and [(18)F]afatinib in lung cancer-bearing mice. EGFR, NSCLC, PET, TKIs
44  2015 Acquisition of docetaxel resistance in breast cancer cells reveals upregulation of ABCB1 expression as a key mediator of resistance accompanied by discrete upregulation of other specific genes and pathways. ---
45  2015 Assessment of modulated cytostatic drug resistance by automated gammaH2AX analysis. CsA, DSB, ETP, MDR, RAPA
46  2015 Chitosan Influences the Expression of P-gp and Metabolism of Norfloxacin in Grass Carp. AUC, CTS, NOR
47  2015 Increased permeability-glycoprotein inhibition at the human blood-brain barrier can be safely achieved by performing PET during peak plasma concentrations of tariquidar. dLop
48  2015 Multidrug resistance 1 (MDR1) 3435C>T gene polymorphism influences the clinical phenotype and methotrexate-induced adverse events in South Indian Tamil rheumatoid arthritis. MDR1, MTX, RA
49  2015 Myriad Molecules to Overcome Efflux Drug Transporters and Drug-Metabolizing Enzymes: A Journey from Synthetic to Natural. ---
50  2015 Pharmacodynamic profile and drug interactions with non-vitamin K antagonist oral anticoagulants: implications for patients with atrial fibrillation. NOACs
51  2015 Polymeric Drug-Delivery Systems: Role in P-gp Efflux System Inhibition. GIT, MDR
52  2015 Ultrasensitive detection of drug resistant cancer cells in biological matrixes using an amperometric nanobiosensor. APBA, HYD, MDR, MDRCC, MWCNT
53  2015 [Interleukin-23 strengthens the anti-apoptotic and drug resistance of human tongue squamous cell carcinoma through the Wingless-related integration site/beta-catenin pathway]. ABCG2, Bcl-2, IL-23, qRT-PCR, siRNA, Wnt
54  2014 Aspirin decreases systemic exposure to clopidogrel through modulation of P-glycoprotein but does not alter its antithrombotic activity. AUC, RPI
55  2014 Combined administration of antibiotics and direct oral anticoagulants: a renewed indication for laboratory monitoring? DOACs
56  2014 Evaluation of the effect of curcumin capsules on glyburide therapy in patients with type-2 diabetes mellitus. AUMC
57  2014 Modeling study of phenylsulfonylfuroxan derivatives as P-gp inhibitors: a combined approach of CoMFA, CoMSIA and HQSAR. CoMFA, CoMSIA, HQSAR, MDR
58  2014 Nanocarrier mediated delivery of siRNA/miRNA in combination with chemotherapeutic agents for cancer therapy: current progress and advances. miRNA, MRP-1, RNAi, siRNA
59  2014 P-glycoprotein and vacuolar ATPase synergistically confer anthracycline resistance to fission yeast and human cells. V-ATPase
60  2014 Relationship between permeability glycoprotein (P-gp) gene expression and enrofloxacin metabolism in Nile Tilapia. ENR, qRT-PCR
61  2014 Same-single-cell analysis using the microfluidic biochip to reveal drug accumulation enhancement by an amphiphilic diblock copolymer drug formulation. MDR, MePEG-b-PCL, PCL5, SASCA-A
62  2014 Synergist bioassays: A simple method for initial metabolic resistance investigation of field Anopheles gambiae s.l. populations. ---
63  2014 Synthesis and evaluation of novel podophyllotoxin derivatives as potential antitumor agents. MDR
64  2013 11C-LY2428703, a positron emission tomographic radioligand for the metabotropic glutamate receptor 1, is unsuitable for imaging in monkey and human brains. BCRP, mGluR1
65  2013 Association between reversal of multidrug resistance by methyl jasmonate and P-glycoprotein ATPase activity in hepatocellular carcinoma. ATP, MTT
66  2013 Baicalin pharmacokinetic profile of absorption process using novel in-vitro model: cytochrome P450 3A4-induced Caco-2 cell monolayers combined with rat intestinal rinse fluids. CYP3A, IF
67  2013 Characterization of efflux transporters involved in distribution and disposition of apixaban. BCRP
68  2013 Ex vivo and in vivo investigations of the effects of extracts of Vernonia amygdalina, Carica papaya and Tapinanthus sessilifolius on digoxin transport and pharmacokinetics: assessing the significance on rat intestinal P-glycoprotein efflux. CP, VA
69  2013 New oral anticoagulants: comparative pharmacology with vitamin K antagonists. DTIs, FXa, INR, OACs, VKAs
70  2013 Pharmacokinetic and pharmacodynamic drug interactions with new oral anticoagulants: what do they mean for patients with atrial fibrillation? CYP, DDIs
71  2013 Radiolabelling and PET brain imaging of the alpha₁-adrenoceptor antagonist Lu AE43936. CsA, MDCK, PET
72  2013 The P-glycoprotein transport system and cardiovascular drugs. ---
73  2012 Antinociceptive effect of intrathecal loperamide: role of mu-opioid receptor and calcium channels. ---
74  2012 Blood-brain barrier permeation and efflux exclusion of anticholinergics used in the treatment of overactive bladder. BBB, CNS, OAB
75  2012 Clinical pharmacokinetics and pharmacodynamics of linagliptin. AUC, DPP
76  2012 Drug efflux transporters and multidrug resistance in acute leukemia: therapeutic impact and novel approaches to mediation. ABC, MDR
77  2012 Drug-drug interactions between ketoconazole and berberine in rats: pharmacokinetic effects benefit pharmacodynamic synergism. AUC, BBR, IC, KTZ
78  2012 Effect of grapefruit juice and ritonavir on pharmacokinetics of lopinavir in Wistar rats. CYP3A, GFJ, LPV, RTV
79  2012 Has the era of individualised medicine arrived for antifungals? A review of antifungal pharmacogenomics. BSEP, CYP450, HSCT, MRP, OAT, OATP
80  2012 HDAC inhibitors synergize antiproliferative effect of sorafenib in renal cell carcinoma cells. ELISA, ERK, HDACIs, RCCs, VEGF, VHL
81  2012 Prognostic evaluation of CapG, gelsolin, P-gp, GSTP1, and Topo-II proteins in non-small cell lung cancer. CapG, CI, HR, IHC, MDR, NSCLC, topo II
82  2011 Adenovirus-mediated p53 gene therapy reverses resistance of breast cancer cells to adriamycin. Ad-p53
83  2011 Expression of multidrug resistance-associated P-glycoprotein in feline tumours. MDR
84  2011 The effect of desacetyluvaricin on the expression of TLR4 and P53 protein in Hepg 2.2.15. Des, HCC, TLR4
85  2010 CRIM1 is expressed at higher levels in drug-resistant than in drug-sensitive myeloid leukemia HL60 cells. DNR
86  2010 Desvenlafaxine for major depressive disorder: incremental clinical benefits from a second-generation serotonin-norepinephrine reuptake inhibitor. SNRI
87  2010 Multidrug resistance reversal agent, NSC77037, identified with a cell-based screening assay. BCRP, MDR, MRP1
88  2010 P-glycoprotein function at the blood-brain barrier in humans can be quantified with the substrate radiotracer 11C-N-desmethyl-loperamide. ---
89  2010 The permeability P-glycoprotein: a focus on enantioselectivity and brain distribution. ---
90  2010 The potential for serum p53 to predict the response to chemotherapy of patients with gastric cancer. ---
91  2010 The role of multixenobiotic transporters in predatory marine molluscs as counter-defense mechanisms against dietary allelochemicals. MRP
92  2009 Tissue distribution of p-glycoprotein in cats. ---
93  2008 11C-loperamide and its N-desmethyl radiometabolite are avid substrates for brain permeability-glycoprotein efflux. ---
94  2008 Assessment of P-gp and MRP1 activities using MultiDrugQuant Assay Kit: a preliminary study of correlation between protein expressions and its functional activities in newly diagnosed acute leukaemia patients. ALL, AML, MDR, MRP1
95  2008 Effect of ivermectin on male fertility and its interaction with P-glycoprotein inhibitor (verapamil) in rats. ---
96  2008 Inhibition of ABC transporters abolishes antimony resistance in Leishmania Infection. KA, MRP1, SAG, Sbr, Sbs
97  2008 Recent advances in the research of P-glycoprotein inhibitors. MDR
98  2008 Retroviral-mediated transfer and functional expression of multidrug resistance gene in human placenta mesenchymal stem cells. GFP, P-MSCs
99  2007 A potential genomic biomarker for the detection of polycyclic aromatic hydrocarbon pollutants: multidrug resistance gene 49 in Drosophila melanogaster. MDR, mdr49, PAHs, PCR
100  2007 ABC transporters and drug resistance in leukemia: was P-gp nothing but the first head of the Hydra? ABC transporters