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■ Abbreviation / Long Form : PA / plasminogen activator

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Abbreviation:   PA  (>> Co-occurring Abbreviation)
Long Form:   plasminogen activator
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No. Year Title Co-occurring Abbreviation
2018 A novel mechanism of plasminogen activation in epithelial and mesenchymal cells. ---
2018 Characteristics of fibrinolytic disorders in acute promyelocytic leukemia. APL, ATO, PAI-1, Pg, Pn, tPA, uPA, uPAR
2018 Computational simulations assessment of mutations impact on streptokinase (SK) from a group G streptococci with enhanced activity - insights into the functional roles of structural dynamics flexibility of SK and stabilization of SK-muplasmin catalytic complex. Pg, Pm, RINs, SK
2018 Effects of TGF-beta1 on plasminogen activation in human dental pulp cells: Role of ALK5/Smad2, TAK1 and MEK/ERK signalling. ELISA, PAI-1, suPAR, TGF-beta1, uPA, uPAR
2018 Lack of durable protection against cotton smoke-induced acute lung injury in sheep by nebulized single chain urokinase plasminogen activator or tissue plasminogen activator. BAL, ISIALI, SCMV
2018 Multifaceted Role of the Urokinase-Type Plasminogen Activator (uPA) and Its Receptor (uPAR): Diagnostic, Prognostic, and Therapeutic Applications. uPA
2018 Plasminogen activator system homeostasis and its dysregulation by ethanol in astrocyte cultures and the developing brain. FASD, PD, tPA
2018 The effect of extended milking intervals (24, 48 and 72 h) on milk yield, milk composition, mammary physiology and welfare traits in dairy ewes. Pg, PL
2018 The Plasminogen Activation System Promotes Neurorepair in the Ischemic Brain. CNS, tPA, uPA, uPAR
10  2018 uPA/uPAR signaling in rheumatoid arthritis: Shedding light on its mechanism of action. FLS, M-CSF, MMPs, RA, suPAR, tPA, uPA
11  2017 Dietary omega-3 polyunsaturated fatty acids induce plasminogen activator activity and DNA damage in rabbit spermatozoa. DPA, omega-3 PUFA
12  2017 tPA Modulation of the Blood-Brain Barrier: A Unifying Explanation for the Pleiotropic Effects of tPA in the CNS. CNS, tPA
13  2017 Tranexamic acid in treatment of melasma: A comprehensive review of clinical studies. TA
14  2017 Urokinase plasminogen activator and receptor promote collagen-induced arthritis through expression in hematopoietic cells. CIA, uPA
15  2016 Combination of Ligusticum chuanxiong and Radix Paeoniae ameliorate focal cerebral ischemic in MCAO rats via endoplasmic reticulum stress-dependent apoptotic signaling pathway. ATF6, Bax, Bcl-2, CHOP, CX, GRP78, H-E, IHC, PAI-1, PERK, qPCR, RT-PCR, TIMP-1, TTC, VEGF, WB, XBP1
16  2016 Decreased expression of the plasminogen activator inhibitor type 1 is involved in degradation of extracellular matrix surrounding cervical cancer stem cells. CSCs, ECM, PAI-1, proMMP-2
17  2016 The plasminogen activation system in neuroinflammation. ---
18  2015 Breaking boundaries-coagulation and fibrinolysis at the neurovascular interface. AD, CNS, MS, NVU
19  2015 Plasminogen Activator Inhibitor-1 in Cancer: Rationale and Insight for Future Therapeutic Testing. PAI-1
20  2015 Targeting of plasminogen activator inhibitor 1 improves fibrinolytic therapy for tetracycline-induced pleural injury in rabbits. alphaM, IPFT, mAbs, PAI-1, PF, sc
21  2014 Elevated tissue plasminogen activator and reduced plasminogen activator inhibitor promote hyperfibrinolysis in trauma patients. ---
22  2014 Serpins promote cancer cell survival and vascular co-option in brain metastasis. ---
23  2014 Transforming growth factor-beta signaling leads to uPA/PAI-1 activation and metastasis: a study on human breast cancer tissues. PAI-1, TGF-beta, TMA, uPA
24  2014 Urokinase plasminogen activator receptor (uPAR) and plasminogen activator inhibitor-1 (PAI-1) are potential predictive biomarkers in early stage oral squamous cell carcinomas (OSCC). OSCC, PAI-1, TMA, uPAR
25  2014 [Thrombolytic agents]. u-PA
26  2013 Cathepsin D stimulates the activities of secreted plasminogen activators in the breast cancer acidic environment. cath-D, PAI-1, tPA, uPA
27  2013 CCl4 induces tissue-type plasminogen activator in rat brain; protective effects of oregano, rosemary or vitamin E. PAI-1, ROS, tPA
28  2013 Effect of growth hormone on plasminogen activator and inhibitor activity in rat. CKD, GH, PAI
29  2013 Expression, purification and characterization of recombinant plasminogen activator from Gloydius brevicaudus venom in Escherichia coli. ELT, GBV-PA, IPTG, rGBV-PA, SV-PA
30  2013 Regulation of plasminogen activator activity and expression by cyclic mechanical stress in rat mandibular condylar chondrocytes. MCCs, TMJ, tPA, uPA, uPAR
31  2013 The plasminogen activator system in the ovine placentome during late gestation and stage-two of parturition. MMP, PLAU, SERPINE1
32  2013 Thrombolysis or anticoagulation for cerebral venous thrombosis: rationale and design of the TO-ACT trial. CVT, mRS, TO-ACT
33  2012 Blood-brain barrier invasion by Cryptococcus neoformans is enhanced by functional interactions with plasmin. BMEC
34  2012 Effect of Escherichia coli lipopolysaccharide on u-PA activity and u-PA and u-PAR RNA expression in a bovine mammary epithelial cell line. LPS, u-PAR
35  2012 Effect of thyroxine on fibrinolytic system in rat. PAI
36  2012 Expression of plasminogen activator-related genes in the adipose tissue of lactating dairy sheep in the early post-weaning period. PAI-1, PAI-2, uPA, uPAR
37  2012 Fertilization outcome could be regulated by binding of oviductal plasminogen to oocytes and by releasing of plasminogen activators during interplay between gametes. OF, ZP
38  2012 Genetic polymorphism of urokinase-type plasminogen activator is interacting with plasminogen activator inhibitor-1 to raise risk of cervical neoplasia. PAI-1, uPA, uPAR
39  2012 Regulation of human thyroid follicular cell function by inhibition of vascular endothelial growth factor receptor signalling. VEGFR, VEGFs
40  2012 Role of vegetation-associated protease activity in valve destruction in human infective endocarditis. IE, MMP, MPO, NETs, PMNs, VG
41  2012 Safety of catheter-delivered plasmin in patients with acute lower extremity arterial or bypass graft occlusion: phaseI results. ---
42  2012 The plasminogen activation system modulates differently adipogenesis and myogenesis of embryonic stem cells. ECM, ESC, iPSCs
43  2012 Tumor necrosis factor alpha stimulates expression and secretion of urokinase plasminogen activator in human dental pulp cells. TNF-alpha, tPA, uPA
44  2012 Ventilator-associated pneumonia is characterized by excessive release of neutrophil proteases in the lung. BALF, HNE, MMPs, TIMPs, VAP
45  2011 A bi-functional anti-thrombosis protein containing both direct-acting fibrin(ogen)olytic and plasminogen-activating activities. ---
46  2011 Historical perspective and future direction of thrombolysis research: the re-discovery of plasmin. ---
47  2011 Regulation of the endothelial plasminogen activator system by fluvastatin. Role of Rho family proteins, actin polymerisation and p38 MAP kinase. DN, EC, PAI-1, tPA
48  2011 Spatiotemporal expression of SERPINE2 in the human placenta and its role in extravillous trophoblast migration and invasion. si
49  2011 Therapeutic modulation of coagulation and fibrinolysis in acute lung injury and the acute respiratory distress syndrome. ALI, ARDS, PAI-1, TF
50  2010 A novel urokinase receptor-targeted inhibitor for plasmin and matrix metalloproteinases suppresses vein graft disease. ATF, BPTI, MMP
51  2010 Effects of intra-articular administration of sodium hyaluronate on plasminogen activator system in temporomandibular joints with osteoarthritis. OA, PAI-1, SH, suPAR, TMJ, uPA
52  2010 In vivo suppression of vein graft disease by nonviral, electroporation-mediated, gene transfer of tissue inhibitor of metalloproteinase-1 linked to the amino terminal fragment of urokinase (TIMP-1.ATF), a cell-surface directed matrix metalloproteinase inhibitor. ATF, MMP, SMC, TIMP-1
53  2010 Inhibition of proteases involved in embryo implantation by cholesterol sulfate. CS, MMPs
54  2010 Nobiletin, a citrus polymethoxyflavonoid, suppresses multiple angiogenesis-related endothelial cell functions and angiogenesis in vivo. EC, ECGS, FGFs, HUVEC, proMMP-2
55  2010 Plasminogen activator inhibitor-1 and vitronectin expression level and stoichiometry regulate vascular smooth muscle cell migration through physiological collagen matrices. LRP, PAI-1, Tg, VN, VSMC, WT
56  2010 Seasonal variation of plasminogen activator activity in spermatozoa and seminal plasma of boar, buck, bull and stallion. PAA
57  2010 Skin wound healing in MMP2-deficient and MMP2 / plasminogen double-deficient mice. MMP, PLG
58  2010 Spatiotemporal expression of the serine protease inhibitor, SERPINE2, in the mouse placenta and uterus during the estrous cycle, pregnancy, and lactation. LC, SERPIN
59  2010 The plasminogen activator system in fibroblasts from systemic sclerosis. dSSc, lSSc, SSc
60  2009 Altered fibrinolytic activities in gastric cancer and uremic patients after intervention. Pg
61  2009 Cell-type specificity of interleukins 1alpha and 1beta on prostaglandin and plasminogen activator production in bovine endometrial cells. 2alpha, IL, IL-1R
62  2009 Differences of proteolytic enzymes and pathological changes in permissive and nonpermissive animal hosts for Angiostrongylus cantonensis infection. CSF, MMP-9
63  2009 Effect of thyroxine on plasminogen activator and inhibitor activity in rat. PAI
64  2009 Glucocorticoid suppression of intraovarian levels of prostaglandins and plasminogen activator activity at ovulation in the rat ovary. DEX, IBMX, LH, PG
65  2009 Keeping the blood flowing-plasminogen activator genes and feeding behavior in vampire bats. ---
66  2009 Novel laminin 5 gamma 2-chain fragments potentiating the limbal epithelial cell outgrowth on amniotic membrane. AM, ECM, Ln5, MMPs, RT-PCR
67  2009 Prostaglandin E2 acts via multiple receptors to regulate plasminogen-dependent proteolysis in the primate periovulatory follicle. hCG, PAI-1, PGE2, tPA
68  2009 Role of hypoxia-inducible factor-1 alpha in the regulation of plasminogen activator activity in rat knee joint chondrocytes. ChIP, ELISA, HIF-1alpha, HRE, IL-1beta, PAI-1, RT-PCR, t-PA, uPA, uPAR
69  2009 Therapeutic administration of plasminogen activator inhibitor-1 prevents hypoxic-ischemic brain injury in newborns. BBB, HI, MMP-9, PAI-1, tPA
70  2009 Thrombospondin 2 inhibits metastasis of human malignant melanoma through microenvironment-modification in NOD/SCID/gammaCnull (NOG) mice. MMPs, NOG, PAI-1, TSP
71  2009 Tissue-type plasminogen activator deficiency attenuates peritoneal fibrosis in mice. alpha-SMA, MMP, MT1, PF, TGF-beta1, TIMP, tPA
72  2008 Comparative efficacies of albendazole and the Chinese herbal medicine long-dan-xie-gan-tan, used alone or in combination, in the treatment of experimental eosinophilic meningitis induced by Angiostrongylus cantonensis. CSF, LDXGT, MMP-9
73  2008 Components of the plasminogen activator system and their complexes in renal cell and bladder cancer: comparison between normal and matched cancerous tissues. PAI, RCC, tPA, uPA
74  2008 Effect of high-pressure treatment at various temperatures on indigenous proteolytic enzymes and whey protein denaturation in bovine milk. HP, PL
75  2008 Effects of different molecular weight hyaluronan products on the expression of urokinase plasminogen activator and inhibitor and gelatinases during the early stage of osteoarthritis. HA, MMP, MW, OA, PAI-1, uPA
76  2008 Elevated urinary plasmin activity resistant to alpha2-antiplasmin in acute poststreptococcal glomerulonephritis. APSGN, IgAN, SI
77  2008 Intraperitoneal infusion of recombinant plasminogen activator inhibitor type 2 induced apoptosis in implanted human colon cancer and inhibited its growth and liver metastasis. rPAI-1
78  2008 Naproxen, meloxicam and methylprednisolone inhibit urokinase plasminogen activator and inhibitor and gelatinases expression during the early stage of osteoarthritis. ELISA, MMP, OA, PAI-1, uPA
79  2008 PAI-1 and functional blockade of SNAI1 in breast cancer cell migration. PAI-1, SNAI1, uPA
80  2008 Plasminogen activator induction facilitates recovery of respiratory function following spinal cord injury. CPP, PMN
81  2008 Plasminogen activators are involved in the degradation of bone by osteoclasts. MMPs
82  2008 Pre-clinical studies of plasmin: superior benefit-to-risk ratio of plasmin compared to tissue plasminogen activator. tPA
83  2008 Protein kinase C synergistically stimulates tumor necrosis factor-alpha-induced secretion of urokinase-type plasminogen activator in human dental pulp cells. PKC, PMA, TNF-alpha, tPA, uPA
84  2008 Pulmonary coagulopathy as a new target in lung injury--a review of available pre-clinical models. ALI, APC, ARDS, AT, TF-FVIIa, TM
85  2008 Review of the role of the plasminogen activator system and vascular endothelial growth factor in subfertility. VEGF
86  2008 Serum amyloid A enhances plasminogen activation: implication for a role in colon cancer. SAA
87  2008 Structural consideration of the formation of the activation complex between the staphylokinase-like streptococcal plasminogen activator PadA and bovine plasminogen. PLG
88  2008 The effect of dietary supplementation with limonene or myo-inositol on the induction of neoplasia and matrix metalloproteinase and plasminogen activator activities in accessory sex organs of male Lobund-Wistar rats. NMU-T, tPA
89  2007 Contribution of macrophages to proteolysis and plasmin activity in ewe bulk milk. Pg, PL, uPA
90  2007 Effect of staphylokinase-derived nonadecapeptide on the activation of plasminogen. LBS, SAK
91  2007 Expression analysis and RNA localization of PAI-RBP1 (SERBP1) in epithelial ovarian cancer: association with tumor progression. PAI-1, PAI-RBP1
92  2007 Expression and localization of extracellular matrix-degrading proteinases and their inhibitors in the bovine mammary gland during development, function, and involution. MMP, TIMP
93  2007 Factors affecting the plasmin-plasminogen system in milk obtained from three Greek dairy sheep breeds with major differences in milk production capacity. Pg, PL, SCC
94  2007 IL-1beta stimulates urokinase-type plasminogen activator expression and secretion in human dental pulp cells. IL-1beta, tPA, uPA
95  2007 Involvement of plasminogen activator and plasminogen activator inhibitor type 1 in spermatogenesis, sperm capacitation, and fertilization. PAI-1, tPA, uPA, uPAR
96  2007 Plasminogen activation by fibroblasts from periodontal ligament and gingiva is not directly affected by chemokines in vitro. GF, PAI, PDL
97  2007 Possible role of the plasminogen activation system in human subfertility. FF, ICSI, OR, PAI-1, tPA, uPA
98  2007 Selective vitamin D receptor modulators and their effects on colorectal tumor growth. DG, MMPs, SVDRM
99  2007 Specific amino acid dependency regulates the cellular behavior of melanoma. FAK, Phe, Tyr
100  2007 The plasminogen activation system in lung disease. PAI-1