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■ Abbreviation / Long Form : PBN / alpha-phenyl-N-tert-butylnitrone

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Abbreviation:   PBN  (>> Co-occurring Abbreviation)
Long Form:   alpha-phenyl-N-tert-butylnitrone
 Abbreviation Variation
 Long Form Variation
 Pair(Abbreviation/Long Form) Variation
No. Year Title Co-occurring Abbreviation
2019 [EXPRESS] Peripheral and central oxidative stress in chemotherapy-induced neuropathic pain. CIPN, ROS, TRPV1
2018 Imaging of a clickable anticancer iridium catalyst. CuAAC, SPAAC
2017 alpha-Phenyl-N-cyclohexyl Nitrones: Preparation and Use as Spin-Traps. ---
2017 Catalytic 1,2-dihydronaphthalene and E-aryl-diene synthesis via CoIII-Carbene radical and o-quinodimethane intermediates. o-QDM
2017 Characterization of a rat model of bortezomib-induced painful neuropathy. ---
2017 Cholesterol-nitrone conjugates as protective agents against lipid oxidation: A model membrane study. DLPC
2017 Mutagenic and Cytotoxicity LQB 123 Profile: Safety and Tripanocidal Effect of a Phenyl-t-Butylnitrone Derivative. ---
2017 Reactive oxygen species increase neuronal excitability via activation of nonspecific cation channel in rat medullary dorsal horn neurons. DIDS, NSCC, ROS, SOD, X/XO
10  2017 Variation in Free Radical Yields from U.S. Marketed Cigarettes. EPR
11  2016 alpha-Aryl-N-aryl nitrones: Synthesis and screening of a new scaffold for cellular protection against an oxidative toxic stimulus. ---
13  2016 Co(III)-Carbene Radical Approach to Substituted 1H-Indenes. DBPO, TEMPO
14  2016 Deficient DNA repair exacerbates ethanol-initiated DNA oxidation and embryopathies in ogg1 knockout mice: gender risk and protection by a free radical spin trapping agent. 8-oxodGuo, ANPC, CRL, HL, OGG1, ROS, YSD
15  2016 Divalent Amino-Acid-Based Amphiphilic Antioxidants: Synthesis, Self-Assembling Properties, and Biological Evaluation. ---
16  2016 Enhanced NADPH oxidases and reactive oxygen species in the mechanism of methanol-initiated protein oxidation and embryopathies in vivo and in embryo culture. DPI, ETYA, MeOH, NOXs, PHS, ROS
17  2016 microRNA-34a-Mediated Down-Regulation of the Microglial-Enriched Triggering Receptor and Phagocytosis-Sensor TREM2 in Age-Related Macular Degeneration. AM, AM-34a, AMD, CAPE, MG, TREM2
18  2016 Protective effects of alpha phenyl-tert-butyl nitrone and ascorbic acid in human adipose derived mesenchymal stem cells from differently aged donors. AA, ADSCs
19  2016 Redox Imbalance in the Peripheral Mechanism Underlying the Mirror-Image Neuropathic Pain Due to Chronic Compression of Dorsal Root Ganglion. DRG, MDA, MINP, PWMT, ROS, SOD
20  2016 Spinal mitochondrial-derived ROS contributes to remifentanil-induced postoperative hyperalgesia via modulating NMDA receptor in rats. NMDA, PWL, PWT, ROS
21  2016 Tlr4-mutant mice are resistant to acute alcohol-induced sterol-regulatory element binding protein activation and hepatic lipid accumulation. SREBP, TG
22  2015 Antinociceptive effects of fisetin against diabetic neuropathic pain in mice: Engagement of antioxidant mechanisms and spinal GABAA receptors. DRG, i.p, ROS, t-BOOH
23  2015 EPR-Spin Trapping and Flow Cytometric Studies of Free Radicals Generated Using Cold Atmospheric Argon Plasma and X-Ray Irradiation in Aqueous Solutions and Intracellular Milieu. Ar-CAP, DBNBS, DMPO, EPR
24  2015 Highly reactive free radicals in electronic cigarette aerosols. EC, EPR
25  2015 Noise-Induced Neural Degeneration and Therapeutic Effect of Antioxidant Drugs. ---
26  2015 OKN-007 decreases free radical levels in a preclinical F98 rat glioma model. DMPO, IST, mMRI
27  2015 PBN (Phenyl-N-Tert-Butylnitrone)-Derivatives Are Effective in Slowing the Visual Cycle and Rhodopsin Regeneration and in Protecting the Retina from Light-Induced Damage. AMD, ERG, PBNDs, RPE
28  2015 Secoisolariciresinol diglycoside, a flaxseed lignan, exerts analgesic effects in a mouse model of type 1 diabetes: Engagement of antioxidant mechanism. i.p, SDG, t-BOOH
29  2014 Dual effect of exogenous nitric oxide on neuronal excitability in rat substantia gelatinosa neurons. cPTIO, CTX, NEM, NO, SG, sGC, SNP, TEA
30  2014 Effect of dietary antioxidants on the cytostatic effect of acrylamide during copper-deficiency in Saccharomyces cerevisiae. CDM, DCF, YPD
31  2014 Non-specific inhibition of ischemia- and acidosis-induced intracellular calcium elevations and membrane currents by alpha-phenyl-N-tert-butylnitrone, butylated hydroxytoluene and trolox. BHT
32  2014 Tempol, an intracellular antioxidant, inhibits tissue factor expression, attenuates dendritic cell function, and is partially protective in a murine model of cerebral malaria. CM, ECs, EGCG, LPS, MitoQ, NADPH, ROS, SOD
33  2013 A role for glutathione, independent of oxidative stress, in the developmental toxicity of methanol. 8-oxodG, BSO, DCFH-DA, EtOH, GD, i.p, MeOH, ROS
34  2013 Activation of C-H bonds in nitrones leads to iridium hydrides with antitumor activity. ICR
35  2013 Effect of pulmonary-generated reactive oxygen species on left-ventricular dysfunction associated with cardio-pulmonary ischemia-reperfusion injury. IR, ROS
36  2013 Nitrone-based therapeutics for neurodegenerative diseases: their use alone or in combination with lanthionines. ---
37  2013 The free radical spin trapping agent phenylbutylnitrone reduces fetal brain DNA oxidation and postnatal cognitive deficits caused by in utero exposure to a non-structurally teratogenic dose of ethanol: a role for oxidative stress. EtOH, ROS
38  2012 2-Benzazepine nitrones protect dopaminergic neurons against 6-hydroxydopamine-induced oxidative toxicity. DA, PCC
39  2012 Antinociceptive effect of phenyl N-tert-butylnitrone, a free radical scavenger, on the rat formalin test. i.p, IT, ROS
40  2012 Atmospheric oxygen tension slows myoblast proliferation via mitochondrial activation. NAC, ROS
41  2012 D-Amino acid oxidase-mediated increase in spinal hydrogen peroxide is mainly responsible for formalin-induced tonic pain. DAAO, ROS
42  2012 Free radical generation induces epithelial-to-mesenchymal transition in lung epithelium via a TGF-beta1-dependent mechanism. BAL, COPD, EMT, IPF, PBECs, SOD3, TGF-beta1
43  2012 Inhibition of ROS-induced apoptosis in endothelial cells by nitrone spin traps via induction of phase II enzymes and suppression of mitochondria-dependent pro-apoptotic signaling. BAEC, DMPO, Nrf2
44  2012 Microwave-assisted synthesis of hydroxyphenyl nitrones with protective action against oxidative stress. LPS, ORAC, PD
45  2012 PBN fails to suppress in delayed neuronal death of hippocampal CA1 injury following transient forebrain ischemia in gerbils. ---
46  2012 Soluble mediators released from PI-IBS patients' colon induced alteration of mast cell: involvement of reactive oxygen species. PARs, PI-IBS, PMCs, ROS, SUP
47  2011 Alpha-phenyl-N-tert-butylnitrone (PBN) prevents light-induced degeneration of the retina by inhibiting RPE65 protein isomerohydrolase activity. ---
48  2011 Alpha-phenyl-N-tert-butylnitrone prevents oxidative stress in a haloperidol-induced animal model of tardive dyskinesia: investigating the behavioural and biochemical changes. AIF, HP, TD, VCMs
49  2011 Desorption electrospray ionisation mass spectrometry reveals in situ modification of a hindered amine light stabiliser resulting from direct N-OR bond cleavage. DESI-MS, HALS
50  2011 Embryopathic effects of thalidomide and its hydrolysis products in rabbit embryo culture: evidence for a prostaglandin H synthase (PHS)-dependent, reactive oxygen species (ROS)-mediated mechanism. 8-oxoG, ASA, ear, ETYA, PGA, PGMA, PHS, ROS, TD
51  2011 Intrathecal administration of antioxidants attenuates mechanical pain hypersensitivity induced by REM sleep deprivation in the rat. i.t, REMSD, ROS, t-BOOH, TEMPOL
52  2011 Isolation of mouse mesenchymal stem cells with normal ploidy from bone marrows by reducing oxidative stress in combination with extracellular matrix. ECM, iPS, MEF-ECM, mMSCs, NAC
53  2011 Reactive oxygen species contribute to neuropathic pain by reducing spinal GABA release. ROS, SG, SNL, t-BOOH
54  2011 Up-regulation of NF-kB-sensitive miRNA-125b and miRNA-146a in metal sulfate-stressed human astroglial (HAG) primary cell cultures. AD, HAG, miRNAs, PDTC, RNAs, ROS
55  2010 Anti-cancer activity of nitrones in the Apc(Min/+) model of colorectal cancer. MRI
56  2010 Antioxidants have a rapid and long-lasting effect on neuritic abnormalities in APP:PS1 mice. AD
57  2010 Calicheamicin gamma1(I) and phenyl tert-butyl nitrone (PBN): observation of a kinetic isotope effect by an ESR study. ---
58  2010 Decreased brainstem function following cardiac arrest and resuscitation in aged rat. HVR
59  2010 Enhancement of the photocatalytic activity of TiO2 nanoparticles by water-soluble complexes of carotenoids. DMSO, EPR
60  2010 Induction of neurite outgrowth by alpha-phenyl-N-tert-butylnitrone through nitric oxide release and Ras-ERK pathway in PC12 cells. NO
61  2010 Interleukin-1beta-induced brain injury and neurobehavioral dysfunctions in juvenile rats can be attenuated by alpha-phenyl-n-tert-butyl-nitrone. IL-1beta
62  2010 Multiparametric assessment of the anti-glioma properties of OKN007 by magnetic resonance imaging. ---
63  2010 Phenyl N-tert-butylnitrone, a free radical scavenger, reduces mechanical allodynia in chemotherapy-induced neuropathic pain in rats. ---
64  2010 Phenyl-alpha-tert-butyl-nitrone and benzonidazole treatment controlled the mitochondrial oxidative stress and evolution of cardiomyopathy in chronic chagasic Rats. BZ
65  2009 Pharmacological assessments of nitric oxide synthase isoforms and downstream diversity of NO signaling in the maintenance of thermal and mechanical hypersensitivity after peripheral nerve injury in mice. AMT, iNOS, l-NAME, nNOS, NOS, ROS, TEMPOL
66  2009 Preparation and evaluation of alpha-phenyl-n-tert-butyl nitrone (PBN)-encapsulated chitosan and PEGylated chitosan nanoparticles. CS, CS-PEG, TEM
67  2009 Reversed redox generation of silyl radicals in a four-electrode flow-through EPR spectroelectrochemical cell. ---
68  2009 Serendipitous findings while researching oxygen free radicals. MB
69  2008 Alpha-phenyl-N-tert-butyl nitrone has scavenging activity against singlet oxygen ((1)O(2)) and attenuates (1)O(2)-induced neuronal cell death. ---
70  2008 Alpha-phenyl-n-tert-butyl-nitrone ameliorates hippocampal injury and improves learning and memory in juvenile rats following neonatal exposure to lipopolysaccharide. HP, LPS
71  2008 alpha-Phenyl-n-tert-butyl-nitrone attenuates lipopolysaccharide-induced brain injury and improves neurological reflexes and early sensorimotor behavioral performance in juvenile rats. i.c, i.c, LPS
72  2008 Alpha-Phenyl-n-tert-butyl-nitrone attenuates lipopolysaccharide-induced neuronal injury in the neonatal rat brain. LPS, PVL
73  2008 alpha-Phenyl-n-tert-butyl-nitrone reduces lipopolysaccharide-induced white matter injury in the neonatal rat brain. LPS, OLs
74  2008 Effectiveness of 4-hydroxy phenyl N-tert-butylnitrone (4-OHPBN) alone and in combination with other antioxidant drugs in the treatment of acute acoustic trauma in chinchilla. AAT, ALCAR, NAC
75  2008 Genetic and pharmacologic manipulation of oxidative stress after neonatal hypoxia-ischemia. 7-NI, GPX1, HI, WT
76  2008 Heteroarylnitrones as drugs for neurodegenerative diseases: synthesis, neuroprotective properties, and free radical scavenger properties. ESR, ORAC
77  2008 In vitro electron paramagnetic resonance characterization of free radicals: relevance to exercise-induced lipid peroxidation and implications of ascorbate prophylaxis. EPR, HCC, PUFA
78  2008 Increased production of mitochondrial superoxide in the spinal cord induces pain behaviors in mice: the effect of mitochondrial electron transport complex inhibitors. ROS, TEMPOL
79  2008 Inhibition of 6-hydroxydopamine-induced oxidative damage by 4,5-dihydro-3H-2-benzazepine N-oxides. 6-OHDA, LPO, PCO, PD
80  2008 Luminal antioxidants enhance the effects of mesalamine in the treatment of chemically induced colitis in rats. MPO, TNBS
81  2008 Maternally administered lipopolysaccharide (LPS) upregulates the expression of heme oxygenase-1 in fetal liver: the role of reactive oxygen species. AG, HO-1, iNOS, LPS, NO, PTX, ROS, TNF-alpha
82  2008 Mitochondrial dysfunction in aging rat brain following transient global ischemia. HNE
83  2008 Mitochondrial generation of reactive oxygen species is enhanced at the Q(o) site of the complex III in the myocardium of Trypanosoma cruzi-infected mice: beneficial effects of an antioxidant. ROS
84  2008 Molecular detection of exercise-induced free radicals following ascorbate prophylaxis in type 1 diabetes mellitus: a randomised controlled trial. ---
85  2008 Nitrones as therapeutics. ---
86  2008 Oxidative stress in the spinal cord is an important contributor in capsaicin-induced mechanical secondary hyperalgesia in mice. ROS, TEMPOL
87  2008 Pharmacological interventions to decompression sickness in rats: comparison of five agents. DCS, MP, TSC
88  2008 Phenyl N-t-butylnitrone, a reactive oxygen species scavenger, reduces zymosan-induced visceral pain in rats. CRD, EMGs, ROS
89  2008 Phenyl-tert-butylnitrone induces tumor regression and decreases angiogenesis in a C6 rat glioma model. MR
90  2008 Reactivity of superoxide radical anion and hydroperoxyl radical with alpha-phenyl-N-tert-butylnitrone (PBN) derivatives. DFT, DMPO, EPR, PR
91  2008 Visualization of the protective ability of a free radical trapping compound against rat C6 and F98 gliomas with diffusion tensor fiber tractography. ADC, CC, DTI, FA, PDW, T2W
92  2007 A new amphiphilic derivative, N-{[4-(lactobionamido)methyl]benzylidene}-1,1-dimethyl-2-(octylsulfanyl)ethylamine N-oxide, has a protective effect against copper-induced fulminant hepatitis in Long-Evans Cinnamon rats at an extremely low concentration compared with its original form alpha-phenyl-N-(tert-butyl) nitrone. LEC
93  2007 Alpha-phenyl-N-tert-butyl nitrone (PBN) derivatives: synthesis and protective action against microvascular damages induced by ischemia/reperfusion. ---
94  2007 Alpha-phenyl-N-tert-butylnitrone-type derivatives bound to beta-cyclodextrins: syntheses, thermokinetics of self-inclusion and application to superoxide spin-trapping. Me2CD-PBN
95  2007 Biphasic mechanism of the toxicity induced by 1-methyl-4-phenylpyridinium ion (MPP+) as revealed by dynamic changes in glucose metabolism in rat brain slices. CMRglc, DAT
96  2007 Delayed loss of cone and remaining rod photoreceptor cells due to impairment of choroidal circulation after acute light exposure in rats. 4-HNE, ONL, RPE, TEM
97  2007 Effect of thiocyanate on the peroxidase and pseudocatalase activities of Leishmania major ascorbate peroxidase. LmAPX, MDA
98  2007 Evaluation of oxidative stress in D-serine induced nephrotoxicity. 4-HNE, ATZ, CAT, HO-1, MDA, NAG, ROS
99  2007 Fine-tuning the amphiphilicity: a crucial parameter in the design of potent alpha-phenyl-N-tert-butylnitrone analogues. ---
100  2007 Gene expression in enhanced apoptosis of human lymphoma U937 cells treated with the combination of different free radical generators and hyperthermia. 6FP